Histamine H2 Antagonists
- Name
- Histamine H2 Antagonists
- Accession Number
- DBCAT000933 (DBCAT002400, DBCAT002656, DBCAT003361, DBCAT003696)
- Description
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
- ATC Classification
- Drugs
Drug Drug Description Asenapine An atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia. Cimetidine A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. Doxepin A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Ebrotidine Ebrotidine is a small molecule drug. The usage of the INN stem '-tidine' in the name indicates that Ebrotidine is a histamine- H2-receptor antagonist, cimetidine derivative. Ebrotidine has a monoisotopic... Epinastine An H1 receptor antagonist used to prevent itching in allergic conjunctivitis. Famotidine A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. Lafutidine Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD). Lavoltidine Lavoltidine has been used in trials studying the diagnostic of Reflux, Gastroesophageal and Gastroesophageal Reflux Disease. Methantheline For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. Metiamide Potential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion. Mifentidine Mifentidine is a small molecule drug. The usage of the INN stem '-tidine' in the name indicates that Mifentidine is a histamine- H2-receptor antagonist, cimetidine derivative. Mifentidine has a monoisotopic... Niperotidine Not Annotated Nizatidine An H2 receptor antagonist used to treat GERD and a variety of ulcers. Olanzapine An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders. Oxmetidine Oxmetidine is a small molecule drug. The usage of the INN stem '-tidine' in the name indicates that Oxmetidine is a histamine- H2-receptor antagonist, cimetidine derivative. Oxmetidine has a monoisotopic... Promethazine A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. Ranitidine A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis. Roxatidine acetate For the treatment of disorders of the upper gastro-intestinal region that are due to an excess of hydrochloric acid in the gastric juice, i.e. duodenal ulcers, benign gastric ulcers. Also... Tiotidine Tiotidine is a small molecule drug. The usage of the INN stem '-tidine' in the name indicates that Tiotidine is a histamine- H2-receptor antagonist, cimetidine derivative. Tiotidine has a monoisotopic... Viloxazine A selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children.