Name
Estranes
Accession Number
DBCAT001043
Description

A group of compounds forming the nucleus of the estrogenic steroid family.

Drugs
DrugDrug Description
EstradiolAn estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
FulvestrantAn estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
Nandrolone decanoateAn anabolic steroid indicated for the management of the anemia of renal insufficiency by increasing hemoglobin and red cell mass.
EstetrolAn estrogen used in combination with drospirenone for oral contraception.
Fluoroestradiol F-18A radiolabeled analog of estradiol used as a contrast agent in the PET imaging of estrogen receptor-positive breast cancer lesions.
Drugs & Drug Targets
DrugTargetType
EstradiolEstrogen receptor alphatarget
EstradiolNuclear receptor subfamily 1 group I member 2target
EstradiolSex hormone-binding globulincarrier
EstradiolEstrogen receptor betatarget
EstradiolCytochrome P450 1A2enzyme
EstradiolUDP-glucuronosyltransferase 1-1enzyme
EstradiolSerum albumincarrier
EstradiolFatty acid-binding protein, intestinalcarrier
EstradiolCytochrome P450 3A4enzyme
EstradiolCytochrome P450 3A5enzyme
EstradiolCytochrome P450 3A7enzyme
EstradiolSolute carrier family 22 member 2transporter
EstradiolSolute carrier family 22 member 3transporter
EstradiolMultidrug resistance-associated protein 7transporter
EstradiolSolute carrier family 22 member 11transporter
EstradiolATP-binding cassette sub-family G member 2transporter
EstradiolSolute carrier organic anion transporter family member 1B1transporter
EstradiolP-glycoprotein 1transporter
EstradiolCytochrome P450 1A1enzyme
EstradiolCytochrome P450 1B1enzyme
EstradiolCytochrome P450 2C19enzyme
EstradiolCytochrome P450 2C8enzyme
EstradiolCytochrome P450 2C9enzyme
EstradiolSolute carrier family 22 member 8transporter
EstradiolSolute carrier organic anion transporter family member 1B3transporter
EstradiolSolute carrier organic anion transporter family member 1C1transporter
EstradiolNeuronal acetylcholine receptor subunit alpha-4target
EstradiolG-protein coupled estrogen receptor 1target
EstradiolATP synthase subunit atarget
EstradiolBeclin-1target
EstradiolUDP-glucuronosyltransferase 2B15enzyme
EstradiolCatechol O-methyltransferaseenzyme
EstradiolUDP-glucuronosyltransferases (UGTs)enzyme
FulvestrantEstrogen receptor alphatarget
FulvestrantCytochrome P450 3A4enzyme
FulvestrantUDP-glucuronosyltransferase 1-1enzyme
Nandrolone decanoateAndrogen receptortarget
Nandrolone decanoateCytochrome P450 19A1enzyme
Nandrolone decanoateAmine oxidase [flavin-containing] Benzyme
Nandrolone decanoateAmine oxidase [flavin-containing] Aenzyme
Nandrolone decanoateProto-oncogene c-Fostarget
Nandrolone decanoate5-hydroxytryptamine 2 receptortarget
Nandrolone decanoate5-hydroxytryptamine receptor 1Btarget
Nandrolone decanoateInsulin-like growth factor 1 receptortarget
Nandrolone decanoateDopamine receptortarget
Nandrolone decanoateUDP-glucuronosyltransferase 2B7enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-4enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 2B4enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-3enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-1enzyme
Nandrolone decanoateUDP-glucuronosyltransferase 1-10enzyme
Nandrolone decanoateSex hormone-binding globulincarrier
EstetrolSerum albumincarrier
EstetrolCytochrome P450 3A4enzyme
EstetrolUDP-glucuronosyltransferase 2B7enzyme
EstetrolEstrogen receptor alphatarget
EstetrolEstrogen receptor betatarget
EstetrolAlpha-1-acid glycoprotein 1carrier
Fluoroestradiol F-18Estrogen receptor alphatarget
Fluoroestradiol F-18Estrogen receptor betatarget
Fluoroestradiol F-18Sex hormone-binding globulincarrier
Fluoroestradiol F-18Serum albumincarrier