Metals, Alkaline Earth

Name
Metals, Alkaline Earth
Accession Number
DBCAT001352
Description

Metals that constitute the group 2 (formerly group IIa) of the periodic table.

Drugs
DrugDrug Description
CalciumA mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency.
Radium Ra 223 dichlorideA radiopharmaceutical agent used to treat patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease.
Magnesium carbonateAn antacid used for symptomatic relief of heartburn, indigestion, and upset stomach.
Strontium chloride Sr-89A radiopharmaceutical agent used for the relief of bone pain in patients with painful skeletal metastases.
BariumBarium is under investigation for the diagnostic of Known or Suspected Abdominal Disease.
Strontium chlorideA medication used to treat bone pain in skeletal metastases.
MagnesiumA medication used for many purposes including constipation, indigestion, magnesium deficiency, and pre-eclampsia.
Radium Ra-223Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC).
Calcium citrateAn ingredient found in a variety of supplements and vitamins.
Drugs & Drug Targets
DrugTargetType
CalciumProtein S100-Btarget
CalciumCalpastatintarget
CalciumCartilage oligomeric matrix proteintarget
CalciumCalmodulintarget
CalciumSpectrin beta chain, non-erythrocytic 1target
CalciumVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
CalciumTroponin C, skeletal muscletarget
CalciumTroponin C, slow skeletal and cardiac musclestarget
CalciumCalcium-transporting ATPase type 2C member 1target
CalciumAmiloride-sensitive amine oxidase [copper-containing]target
CalciumProtein S100-A13target
CalciumAlkaline phosphatase, placental typetarget
CalciumProtein S100-A8target
CalciumProtein S100-A9target
CalciumProtein S100-A2target
CalciumCeruloplasmintarget
CalciumBone morphogenetic protein 4target
CalciumMatrix Gla proteintarget
CalciumProtocadherin-19target
CalciumProgrammed cell death protein 6target
Magnesium carbonateTransient receptor potential cation channel subfamily M member 6transporter
Magnesium carbonateSolute carrier family 41 member 3transporter
Magnesium carbonateMetal transporter CNNM2transporter
Magnesium carbonateTransient receptor potential cation channel subfamily M member 7transporter
Magnesium carbonateGlutamate (NMDA) receptortarget
Strontium chloride Sr-89Alkaline phosphatase, placental-likeenzyme
Strontium chloride Sr-89Alkaline phosphatase, tissue-nonspecific isozymeenzyme
Strontium chloride Sr-89Adenosine triphosphate (ATP)enzyme
Strontium chloride Sr-89Sodium/calcium exchanger 1transporter
Strontium chloride Sr-89Voltage-dependent T-type calcium channel subunit alpha-1Itransporter
MagnesiumSerum albumincarrier
MagnesiumClaudin-16transporter
MagnesiumTransient receptor potential cation channel subfamily M member 6transporter
MagnesiumTransient receptor potential cation channel subfamily M member 7transporter
MagnesiumSolute carrier family 41 member 1transporter
MagnesiumSolute carrier family 41 member 3transporter
MagnesiumMagnesium transporter MRS2 homolog, mitochondrialtransporter
Calcium citrateTransient receptor potential cation channel subfamily V member 6transporter
Calcium citrateCalbindincarrier
Calcium citrateProtein S100-Gcarrier
Calcium citrateSodium/calcium exchanger 1transporter
Calcium citrateTransient receptor potential cation channel subfamily V member 5transporter
Calcium citrateExtracellular calcium-sensing receptortarget
Calcium citrateCalreticulintarget
Calcium citrateCalcium and integrin-binding protein 1target
Calcium citrateProgrammed cell death protein 6target
Calcium citrateSorcintarget
Calcium citrateCalcineurin B homologous protein 1target
Calcium citrateSPARCtarget
Calcium citrateCalnexintarget
Calcium citrateFibrillin-2target
Calcium citrateProtein S100-Btarget
Calcium citrateCalsequestrin-2target
Calcium citrateRegucalcintarget
Calcium citratePeflintarget
Calcium citrateProtein S100-A6target
Calcium citrateTranslationally-controlled tumor proteintarget
Calcium citrateCalcium and integrin-binding family member 2target
Calcium citrateProtein S100-A13target
Calcium citrateCalsequestrin-1target
Calcium citrateNucleobindin-1target
Calcium citrateNucleobindin-2target
Calcium citrateCalmodulintarget
Calcium citrateFibrillin-3target
Calcium citrateGrancalcintarget
Calcium citrateCalcium-dependent secretion activator 1target
Calcium citrateSerum albumincarrier
Calcium citrateCalmodulin-2target
Calcium citrateCalmodulin-3target
Calcium citrateProtein S100-A16target
Calcium citrateCalretinintarget
Calcium citrateCalcyphosintarget
Calcium citrateCalcium-dependent secretion activator 2target
Calcium citrateCalreticulin-3target
Calcium citrateRyanodine receptor 1transporter
Calcium citrateRyanodine receptor 2transporter
Calcium citratePolycystic kidney disease 2-like 1 proteintransporter
Calcium citrateNeurexin-1target
Calcium citrateNeuronal calcium sensor 1target
Calcium citrateRyanodine receptor 3transporter
Calcium citratePolycystic kidney disease protein 1-like 3transporter
Calcium citrateCation channel sperm-associated protein 1transporter
Calcium citrateVoltage-dependent L-type calcium channeltransporter
Calcium citrateVoltage-dependent P/Q-type calcium channeltransporter
Calcium citrateVoltage-dependent T-type calcium channeltransporter
Calcium citrateVoltage-dependent R-type calcium channeltransporter