Carbapenems

Name
Carbapenems
Accession Number
DBCAT001395
Description

A group of beta-lactam antibiotics in which the sulfur atom in the thiazolidine ring of the penicillin molecule is replaced by a carbon atom. THIENAMYCINS are a subgroup of carbapenems which have a sulfur atom as the first constituent of the side chain.

ATC Classification
Drugs
DrugDrug Description
ImipenemA carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.
MeropenemA carbapenem antibiotic used to treat a wide variety of infections in the body.
BiapenemA carbapenem antibiotic indicated in the treatment of bacterial infections.
ErtapenemA carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms.
DoripenemAn antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections.
Drugs & Drug Targets
DrugTargetType
ImipenemPenicillin-binding protein 1Atarget
ImipenemPenicillin-binding protein 1Btarget
ImipenemPenicillin-binding protein 2target
ImipenemPenicillin-binding protein 3target
ImipenemDipeptidase 1enzyme
ImipenemPenicillin-binding protein 4target
ImipenemBeta-lactamase SHV-1enzyme
ImipenemBeta-lactamase TEMenzyme
ImipenemBeta-lactamase CTX-Menzyme
ImipenemBeta-lactamase (KPC-2)enzyme
MeropenemD-alanyl-D-alanine carboxypeptidase DacBtarget
MeropenemBeta-lactamase OXA-10enzyme
MeropenemDipeptidase 1enzyme
ErtapenemPenicillin-binding protein 2target
ErtapenemPeptidoglycan synthase FtsItarget
ErtapenemPenicillin-binding protein 1Atarget
ErtapenemD-alanyl-D-alanine carboxypeptidase DacCtarget
ErtapenemD-alanyl-D-alanine carboxypeptidase DacBtarget
ErtapenemPenicillin-binding protein 1Btarget
ErtapenemPeptidoglycan synthase FtsItarget
ErtapenemPenicillin-binding protein 2target
DoripenemDipeptidase 1enzyme
DoripenemPenicillin-binding protein 1Atarget
DoripenemPenicillin-binding protein 1Btarget
DoripenemPenicillin-binding protein 2target
DoripenemPenicillin-binding protein 3target
DoripenemPenicillin-binding protein 4target
DoripenemSolute carrier family 22 member 8transporter