- Plasma Substitutes
- Accession Number
Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.
Drug Drug Description Hydroxyethyl Starch A plasma volume substitute used to treat and prevent hypovolemia. Dextran A low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures. Pentastarch A plasma volume expander used as an adjunct in the management of shock due to hemorrhage, surgery, sepsis, burns or other trauma. Povidone When in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns. Plasma protein fraction (human) A plasma protein solution used to treat coagulation factor deficiencies, reverse anticoagulant effects, and shock from a loss of plasma fluids, and is also used in plasma exchange procedures. Polygeline A medication used for plasma volume expansion. Perfluorodecalin Perfluorodecalin is under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh... Succinylated gelatin A plasma volume expander indicated alone or in combination with blood transfusions.
- Drugs & Drug Targets
Drug Target Type