Low-Ceiling Diuretics, Excl. Thiazides

Low-Ceiling Diuretics, Excl. Thiazides
Accession Number

Not Available

ATC Classification
DrugDrug Description
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
QuinethazoneUsed to treat hypertension.
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
MersalylElevated blood pressure, edema [L1577, L1585].
CicletanineCicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
MeticraneMeticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure .
MefrusideNot Annotated
ClorexoloneNot Annotated
ClofenamideNot Annotated
FenquizoneNot Annotated
ClopamideClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
XipamideA diuretic indicated in the treatment of edema.
ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
MetolazoneA thiazide-like diuretic used to treat hypertension.
PotassiumA medication used to treat hypokalemic conditions and to clear the colon prior to colonoscopy.
Drugs & Drug Targets
IndapamideCytochrome P450 3A4enzyme
IndapamideSolute carrier family 12 member 3target
IndapamideEpoxide hydrolase 1enzyme
Indapamidealpha1-acid glycoproteincarrier
IndapamideSerum albumincarrier
QuinethazoneCarbonic anhydrase 1target
QuinethazoneCarbonic anhydrase 2target
QuinethazoneSolute carrier family 12 member 1target
QuinethazoneSolute carrier family 12 member 2target
QuinethazoneSolute carrier family 12 member 3target
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
MersalylAlkaline phosphatase, tissue-nonspecific isozymetarget
MersalylMonocarboxylate transporter 1target
MersalylInter-alpha-trypsin inhibitor heavy chain H1enzyme
MersalylPhosphoenolpyruvate carboxykinase, cytosolic [GTP]enzyme
ChlorthalidoneSolute carrier family 12 member 1target
ChlorthalidoneSerum albumincarrier
ChlorthalidoneCarbonic anhydrase 1target
MetolazoneSolute carrier family 12 member 3target
PotassiumSodium/potassium-transporting ATPase subunit alpha-1target
PotassiumSodium/potassium-transporting ATPase subunit alpha-1transporter
PotassiumSolute carrier family 12 member 1transporter