Topical Products for Joint and Muscular Pain

Name
Topical Products for Joint and Muscular Pain
Accession Number
DBCAT002314
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Dimethyl sulfoxideA reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
OxyphenbutazoneA nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain.
TolperisoneA muscle relaxant used to relieve spasticity after stroke in adults.
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
FelbinacNot Available
EtofenamateAn NSAID used to treat muscle and joint pain.
ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
FentiazacNot Annotated
SuxibuzoneNot Annotated
IdrocilamideNot Annotated
NifenazoneNot Annotated
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
TolazolineA vasodilator used to treat pulmonary artery anomalies.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Niflumic acidA cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
NimesulideA cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
BenzydamineA locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy.
DexketoprofenAn NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain.
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
FeprazoneNot Annotated
BendazacA non-steroidal anti-inflammatory drug (NSAID) available as an eye drop for the treatment of cataracts and as a topical cream for the treatment of dermatitis, eczema, hives, skin ulcers and other inflammatory skin conditions.
MofebutazoneNot Annotated
LoxoprofenAn NSAID used to treat pain and inflammation in musculoskeletal conditions.
EsflurbiprofenAn NSAID formulated as a topical product for osteoarthritis associated joint pain and inflammation.
Drugs & Drug Targets
DrugTargetType
TolmetinProstaglandin G/H synthase 1target
TolmetinProstaglandin G/H synthase 2target
TolmetinSolute carrier family 22 member 6transporter
TolmetinTryptophan 2,3-dioxygenaseenzyme
TolmetinMyeloperoxidaseenzyme
TolmetinAlbumincarrier
PhenylbutazoneProstaglandin G/H synthase 2target
PhenylbutazoneProstacyclin synthasetarget
PhenylbutazoneCytochrome P450 2C9enzyme
PhenylbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneOrganic anion transporter 3transporter
PhenylbutazoneSolute carrier family 22 member 11transporter
PhenylbutazoneProstaglandin G/H synthase 1target
PhenylbutazoneCytochrome P450 3A4enzyme
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidPolyunsaturated fatty acid 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
Dimethyl sulfoxideTransthyretincarrier
Dimethyl sulfoxideCytochrome P450 2C19enzyme
Dimethyl sulfoxideCytochrome P450 2D6enzyme
Dimethyl sulfoxideCytochrome P450 3A4enzyme
Dimethyl sulfoxideInterleukin-5 receptor subunit alphatarget
Dimethyl sulfoxideMucin-16target
Dimethyl sulfoxideMyc proto-oncogene proteintarget
OxyphenbutazoneGroup IIE secretory phospholipase A2target
OxyphenbutazoneAlbumincarrier
OxyphenbutazoneSolute carrier family 22 member 6transporter
OxyphenbutazoneAlbumintarget
TolperisoneCytochrome P450 1A2enzyme
TolperisoneSodium channel protein type 11 subunit alphatarget
AceclofenacCytochrome P450 2C9enzyme
AceclofenacProstaglandin G/H synthase 2target
AceclofenacProstaglandin G/H synthase 1target
FelbinacProcathepsin Ltarget
FelbinacProstaglandin G/H synthase 1target
FelbinacProstaglandin G/H synthase 2target
EtofenamateThyroxine-binding globulincarrier
ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
ZucapsaicinCytochrome P450 1A2enzyme
ZucapsaicinCytochrome P450 2C19enzyme
ZucapsaicinCytochrome P450 2C9enzyme
ZucapsaicinCytochrome P450 2E1enzyme
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1A9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinAlbumincarrier
IndomethacinATP-binding cassette sub-family C member 3transporter
IndomethacinATP-binding cassette sub-family C member 4transporter
IndomethacinATP-binding cassette sub-family C member 6transporter
IndomethacinATP-dependent translocase ABCB1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinOrganic anion transporter 3transporter
IndomethacinATP-binding cassette sub-family C member 2transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinHepatic sodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1A1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
IndomethacinInterferon-induced, double-stranded RNA-activated protein kinasetarget
IndomethacinHuman Cyclooxygenasestarget
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamAlbumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamOrganic anion transporter 3transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacAlbumincarrier
DiclofenacATP-binding cassette sub-family C member 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacOrganic anion transporter 3transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1A3enzyme
DiclofenacUDP-glucuronosyltransferase 1A9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacPolyunsaturated fatty acid 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacATP-dependent translocase ABCB1transporter
FlurbiprofenProstaglandin G/H synthase 2target
FlurbiprofenProstaglandin G/H synthase 1target
FlurbiprofenCytochrome P450 2C9enzyme
FlurbiprofenAlbumincarrier
FlurbiprofenATP-binding cassette sub-family C member 4transporter
FlurbiprofenSolute carrier family 22 member 6transporter
FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
FlurbiprofenUDP-glucuronosyltransferase 1A1enzyme
FlurbiprofenUDP-glucuronosyltransferase 1A3enzyme
FlurbiprofenUDP-glucuronosyltransferase 1A9enzyme
FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenAlbumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenATP-dependent translocase ABCB1transporter
NaproxenUDP-glucuronosyltransferase 1A3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1A7enzyme
NaproxenUDP-glucuronosyltransferase 1A8enzyme
NaproxenUDP-glucuronosyltransferase 1A9enzyme
NaproxenUDP-glucuronosyltransferase 1A10enzyme
NaproxenOrganic anion transporter 3transporter
NaproxenPancreatic triacylglycerol lipasetarget
TolazolineAlpha-1A adrenergic receptortarget
TolazolineAlpha-2A adrenergic receptortarget
TolazolineHistamine H1 receptortarget
TolazolineHistamine H2 receptortarget
TolazolineAlpha-2C adrenergic receptortarget
TolazolineAlpha-2B adrenergic receptortarget
TolazolineD(2) dopamine receptortarget
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenAlbumincarrier
KetoprofenATP-binding cassette sub-family C member 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenOrganic anion transporter 3transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1A1enzyme
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenAlbumincarrier
IbuprofenATP-binding cassette sub-family C member 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenOrganic anion transporter 3transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenATP-dependent translocase ABCB1transporter
IbuprofenUDP-glucuronosyltransferase 1A3enzyme
IbuprofenUDP-glucuronosyltransferase 1A9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
IbuprofenC-X-C chemokine receptor type 1target
IbuprofenC-X-C chemokine receptor type 2target
IbuprofenInterleukin-8target
RabeprazolePotassium-transporting ATPase alpha chain 1target
RabeprazoleCytochrome P450 3A4enzyme
RabeprazoleCytochrome P450 2C19enzyme
RabeprazoleBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
RabeprazoleCytochrome P450 1A1enzyme
RabeprazoleCytochrome P450 1A2enzyme
RabeprazoleCytochrome P450 2C9enzyme
RabeprazoleCytochrome P450 2D6enzyme
RabeprazoleCytochrome P450 2C8enzyme
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1A9target
Niflumic acidUDP-glucuronosyltransferase 1A9enzyme
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
NimesulideTumor necrosis factor ligand superfamily member 10target
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
BenzydamineProstaglandin G/H synthase 1target
BenzydamineProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacPolyamine deacetylase HDAC10target
BendazacFree radicalstarget
BendazacProstaglandin G/H synthase 1target
BendazacProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 1target
LoxoprofenCarbonyl reductase [NADPH] 1enzyme
LoxoprofenCytochrome P450 3A Subfamilyenzyme
LoxoprofenUDP-glucuronosyltransferase 2B7enzyme
EsflurbiprofenGamma-secretase subunit APH-1Atarget
EsflurbiprofenGamma-secretase subunit PEN-2target
EsflurbiprofenPresenilin-1target
EsflurbiprofenPresenilin-2target
EsflurbiprofenProstaglandin G/H synthase 2target
EsflurbiprofenProstaglandin G/H synthase 1target
EsflurbiprofenGamma-secretase subunit APH-1Btarget
EsflurbiprofenNicastrintarget