Corticosteroids for Systemic Use

Name
Corticosteroids for Systemic Use
Accession Number
DBCAT002378
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
FludrocortisoneA mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
ParamethasoneFor the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
AldosteroneA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
MeprednisoneNot Annotated
DeflazacortA corticosteroid used to treat Duchenne muscular dystrophy.
CortivazolCortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
PrednylidenePrednylidene is an experimental systemic glucocorticoid.
CloprednolCloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma. [A31775,A31776]
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
FluprednisoloneA synthetic glucocorticoid with anti-inflammatory properties.
MelengestrolMelengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals.
FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
CortisoneA naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to...
OsilodrostatAn oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
Drugs & Drug Targets
DrugTargetType
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
CorticotropinAdrenocorticotropic hormone receptortarget
CorticotropinCorticoliberintarget
Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CorticotropinCytochrome P450 3A4enzyme
FludrocortisoneMineralocorticoid receptortarget
FludrocortisoneGlucocorticoid receptortarget
FludrocortisoneCytochrome P450 3A4enzyme
FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
FludrocortisoneSerum albumincarrier
FludrocortisoneCorticosteroid-binding globulincarrier
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
TrilostaneEstrogen receptor betatarget
TrilostaneEstrogen receptor alphatarget
ParamethasoneCorticosteroid-binding globulincarrier
ParamethasoneGlucocorticoid receptortarget
ParamethasoneCytochrome P450 3A4enzyme
ParamethasoneCytochrome P450 3A5enzyme
AldosteroneMineralocorticoid receptortarget
AldosteroneP-glycoprotein 1transporter
AldosteroneSolute carrier family 22 member 5transporter
AldosteroneSolute carrier organic anion transporter family member 1A2transporter
AldosteroneCytochrome P450 11B1, mitochondrialenzyme
AldosteroneCytochrome P450 11B2, mitochondrialenzyme
AldosteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
AldosteroneGlucocorticoid receptortarget
AldosteroneCytochrome P450 3A4enzyme
MeprednisoneSerum albumincarrier
MeprednisoneCytochrome P450 3A4enzyme
MeprednisoneCytochrome P450 3A5enzyme
DeflazacortCytochrome P450 3A4enzyme
DeflazacortGlucocorticoid receptortarget
DeflazacortCytochrome P450 3A5enzyme
CortivazolGlucocorticoid receptortarget
CortivazolCytochrome P450 3A4enzyme
CortivazolCytochrome P450 3A5enzyme
PrednylideneCytochrome P450 3A4enzyme
PrednylideneCytochrome P450 3A5enzyme
CloprednolCytochrome P450 3A4enzyme
CloprednolCytochrome P450 3A5enzyme
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneP-glycoprotein 1transporter
BetamethasoneCytochrome P450 19A1enzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneSerum albumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneSerum albumincarrier
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneP-glycoprotein 1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneSolute carrier family 22 member 8transporter
Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
PrednisoloneCorticosteroid-binding globulincarrier
PrednisoloneCytochrome P450 3A4enzyme
PrednisoloneGlucocorticoid receptortarget
PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
PrednisoloneP-glycoprotein 1transporter
PrednisoloneSerum albumincarrier
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
Cortisone acetateGlucocorticoid receptortarget
Cortisone acetateCytochrome P450 3A4enzyme
Cortisone acetateCytochrome P450 3A5enzyme
FluprednisoloneCytochrome P450 3A4enzyme
MelengestrolCytochrome P450 3A4enzyme
FlunisolideCorticosteroid-binding globulincarrier
FlunisolideGlucocorticoid receptortarget
FlunisolideCytochrome P450 3A4enzyme
CortisoneCytochrome P450 3A4enzyme
CortisoneCytochrome P450 3A5enzyme
OsilodrostatCytochrome P450 11B1, mitochondrialtarget
OsilodrostatCytochrome P450 11B2, mitochondrialtarget
OsilodrostatCytochrome P450 3A4enzyme
OsilodrostatCytochrome P450 2B6enzyme
OsilodrostatCytochrome P450 2D6enzyme
OsilodrostatUDP-glucuronosyltransferase 1-4enzyme
OsilodrostatUDP-glucuronosyltransferase 2B7enzyme
OsilodrostatUDP-glucuronosyltransferase 2B10enzyme
OsilodrostatCytochrome P450 3A5enzyme
OsilodrostatCytochrome P450 1A2enzyme
OsilodrostatCytochrome P450 2C19enzyme
OsilodrostatCytochrome P450 2E1enzyme
OsilodrostatUDP-glucuronosyltransferase 1A1enzyme
OsilodrostatSolute carrier organic anion transporter family member 1B1transporter
OsilodrostatSolute carrier family 22 member 1transporter
OsilodrostatSolute carrier family 22 member 2transporter
OsilodrostatSolute carrier family 22 member 6transporter
OsilodrostatSolute carrier family 22 member 8transporter
OsilodrostatMultidrug and toxin extrusion protein 1transporter