BCRP/ABCG2 Inhibitors

Accession Number

DBCAT002662

Description

Not Available

Drugs

Drug	Drug Description
Quercetin	Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Naringenin	Not Available
Novobiocin	For the treatment of infections due to staphylococci and other susceptible organisms
Estrone	An estrogen used to treat perimenopausal and postmenopausal symptoms.
Saquinavir	An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
Omeprazole	A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
Hesperetin	For lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase...
Genistein	Currently Genistein is being studied in clinical trials as a treatment for prostate cancer.
Nelfinavir	A viral protease inhibitor used in the treatment of HIV infection.
Diethylstilbestrol	Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
Ritonavir	An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Pantoprazole	A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
Cyclosporine	A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
Taurocholic acid	The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats...
Imatinib	A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
Estradiol	An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
Daidzin	Not Available
Sorafenib	A kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
Sunitinib	A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Dronabinol	A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
Buprenorphine	A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
Sulfasalazine	An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
Telmisartan	An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
Dexamethasone	A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Dasatinib	A tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
Rabeprazole	A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Elacridar	For the treatment of solid tumors.
Nilotinib	A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
Erlotinib	An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
Vandetanib	An antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
Cabazitaxel	An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
Rilpivirine	A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
Vismodegib	A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
Regorafenib	A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
Ponatinib	A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
Dabrafenib	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Afatinib	An antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.
Cobicistat	A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
Rolapitant	A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy.
Daclatasvir	A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Alectinib	A kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Dasabuvir	A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Velpatasvir	A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis.
Simeprevir	A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
Topiroxostat	Indicated for the treatment of gout and hyperurcemia in Japan.
Voxilaprevir	A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
Enasidenib	An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Pibrentasvir	A Hepatitis C NS5A inhibitor used to treat Hepatitis C.
Glecaprevir	A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
Abemaciclib	A medication used to treat HR+ HER2- advanced or metastatic breast cancer.
Letermovir	An antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).
Brigatinib	An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Rucaparib	An anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
Baricitinib	A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
Cannabidiol	An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
Estradiol acetate	An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause.
Estradiol benzoate	Estradiol benzoate is not currently available in any FDA or Health Canada approved products.
Estradiol cypionate	An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism.
Estradiol dienanthate	Estradiol dienanthate is not currently available in any FDA or Health Canada approved products.
Estradiol valerate	An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception.
Isavuconazole	Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
Nabiximols	In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have...
Medical Cannabis	The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
Avatrombopag	A thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease who are scheduled to undergo a procedure.
Gefitinib	A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
Safinamide	A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
Paritaprevir	A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Fostamatinib	A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
Lansoprazole	A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Pravastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
Dovitinib	Investigated for use/treatment in multiple myeloma and solid tumors.
Eltrombopag	A thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
Teriflunomide	A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
Vemurafenib	A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
Progesterone	A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
Fusidic acid	A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
Dacomitinib	A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
Venetoclax	A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
Gilteritinib	An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.
Glasdegib	A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy.
Olaparib	A chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.
Palbociclib	An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
Beclomethasone dipropionate	An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
Fedratinib	Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk.
Istradefylline	A selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease.
Caffeine	A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
Lasmiditan	An oral 5HT1F agonist used for the acute treatment of migraine headache with or without aura.
Darolutamide	An androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer.
Upadacitinib	An oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis in adult patients who did not respond well to methotrexate.
Tafamidis	A medication used to treat transthyretin-mediated amyloidosis.
Capmatinib	A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping.
Selpercatinib	A RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations.
Ripretinib	A kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST).
Clofazimine	A riminophenazine antimycobacterial used to treat leprosy.
Dexamethasone acetate	Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
Fostemsavir	An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.
Pralsetinib	A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
Lonafarnib	A potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies.
Relugolix	An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.

Drugs & Drug Targets

Drug	Target	Type
Quercetin	Tyrosine-protein kinase HCK	target
Quercetin	Cytochrome P450 2C8	enzyme
Quercetin	Multidrug resistance-associated protein 1	transporter
Quercetin	Canalicular multispecific organic anion transporter 1	transporter
Quercetin	Monocarboxylate transporter 2	transporter
Quercetin	Solute carrier organic anion transporter family member 2B1	transporter
Quercetin	P-glycoprotein 1	transporter
Quercetin	Monocarboxylate transporter 1	transporter
Quercetin	ATP-binding cassette sub-family G member 2	transporter
Quercetin	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	target
Quercetin	UDP-glucuronosyltransferase 3A1	target
Quercetin	ATP synthase subunit alpha, mitochondrial	target
Quercetin	ATP synthase subunit beta, mitochondrial	target
Quercetin	ATP synthase subunit gamma, mitochondrial	target
Quercetin	Serine/threonine-protein kinase pim-1	target
Quercetin	HTH-type transcriptional regulator TtgR	target
Quercetin	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	target
Quercetin	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ	target
Quercetin	Serine/threonine-protein kinase 17B	target
Quercetin	Estrogen receptor alpha	target
Quercetin	Estrogen receptor beta	target
Quercetin	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Quercetin	Serum albumin	carrier
Quercetin	Aryl hydrocarbon receptor	target
Quercetin	Cytochrome P450 1B1	target
Quercetin	Actin, cytoplasmic 1	target
Quercetin	Casein kinase II subunit alpha	target
Quercetin	Casein kinase II subunit beta	target
Quercetin	Eukaryotic translation initiation factor 3 subunit F	target
Quercetin	Heat shock protein HSP 90-alpha	target
Quercetin	Heat shock-related 70 kDa protein 2	target
Quercetin	RuvB-like 2	target
Quercetin	Splicing factor 3B subunit 3	target
Quercetin	Ubiquitin-like modifier-activating enzyme 1	target
Quercetin	Sex hormone-binding globulin	target
Quercetin	Carbonyl reductase [NADPH] 1	target
Quercetin	CCAAT/enhancer-binding protein beta	target
Quercetin	Nuclear receptor subfamily 1 group I member 2	target
Quercetin	Solute carrier organic anion transporter family member 1B1	transporter
Naringenin	Solute carrier organic anion transporter family member 2B1	transporter
Naringenin	P-glycoprotein 1	transporter
Naringenin	Multidrug resistance-associated protein 1	transporter
Naringenin	ATP-binding cassette sub-family G member 2	transporter
Naringenin	HTH-type transcriptional regulator TtgR	target
Naringenin	Estrogen receptor alpha	target
Naringenin	Aldo-keto reductase family 1 member C1	target
Naringenin	Cytochrome P450 1B1	target
Naringenin	KAT8 regulatory NSL complex subunit 3	target
Naringenin	Sex hormone-binding globulin	target
Naringenin	Cytochrome P450 19A1	target
Naringenin	Estrogen receptor beta	target
Novobiocin	DNA gyrase subunit B	target
Novobiocin	Solute carrier family 22 member 6	transporter
Novobiocin	Solute carrier family 22 member 8	transporter
Novobiocin	Solute carrier family 22 member 11	transporter
Novobiocin	ATP-binding cassette sub-family G member 2	transporter
Novobiocin	DNA topoisomerase 1	target
Novobiocin	Solute carrier organic anion transporter family member 1B1	transporter
Novobiocin	Solute carrier organic anion transporter family member 1B3	transporter
Novobiocin	Solute carrier organic anion transporter family member 2B1	transporter
Estrone	Estrogen receptor alpha	target
Estrone	Cytochrome P450 1A2	enzyme
Estrone	Cytochrome P450 1A1	enzyme
Estrone	Serum albumin	carrier
Estrone	Solute carrier organic anion transporter family member 2B1	transporter
Estrone	P-glycoprotein 1	transporter
Estrone	Solute carrier organic anion transporter family member 1A2	transporter
Estrone	ATP-binding cassette sub-family G member 2	transporter
Estrone	Solute carrier organic anion transporter family member 1B1	transporter
Estrone	Cytochrome P450 3A4	enzyme
Estrone	Cytochrome P450 1B1	enzyme
Estrone	Cytochrome P450 2B6	enzyme
Estrone	Cytochrome P450 2C9	enzyme
Estrone	Cytochrome P450 2E1	enzyme
Estrone	Cytochrome P450 3A5	enzyme
Estrone	Estrogen receptor beta	target
Estrone	Androgen receptor	target
Estrone	Cytochrome P450 19A1	target
Estrone	Sex hormone-binding globulin	target
Estrone	Solute carrier family 22 member 8	transporter
Saquinavir	Human immunodeficiency virus type 1 protease	target
Saquinavir	Cytochrome P450 3A4	enzyme
Saquinavir	Cytochrome P450 3A5	enzyme
Saquinavir	Alpha-1-acid glycoprotein 1	carrier
Saquinavir	Serum albumin	carrier
Saquinavir	Cytochrome P450 3A7	enzyme
Saquinavir	P-glycoprotein 1	transporter
Saquinavir	Solute carrier family 22 member 1	transporter
Saquinavir	Solute carrier organic anion transporter family member 1A2	transporter
Saquinavir	ATP-binding cassette sub-family G member 2	transporter
Saquinavir	Solute carrier organic anion transporter family member 1B1	transporter
Saquinavir	Multidrug resistance-associated protein 1	transporter
Saquinavir	Canalicular multispecific organic anion transporter 1	transporter
Saquinavir	Cytochrome P450 2C8	enzyme
Saquinavir	Cytochrome P450 2D6	enzyme
Saquinavir	Solute carrier organic anion transporter family member 2B1	transporter
Saquinavir	Bile salt export pump	transporter
Omeprazole	Potassium-transporting ATPase alpha chain 1	target
Omeprazole	Cytochrome P450 2C19	enzyme
Omeprazole	Cytochrome P450 3A4	enzyme
Omeprazole	Cytochrome P450 2C9	enzyme
Omeprazole	Cytochrome P450 1A2	enzyme
Omeprazole	Canalicular multispecific organic anion transporter 2	transporter
Omeprazole	P-glycoprotein 1	transporter
Omeprazole	ATP-binding cassette sub-family G member 2	transporter
Omeprazole	Cytochrome P450 1A1	enzyme
Omeprazole	Cytochrome P450 1B1	enzyme
Omeprazole	Cytochrome P450 2C18	enzyme
Omeprazole	Cytochrome P450 2C8	enzyme
Omeprazole	Cytochrome P450 2D6	enzyme
Omeprazole	Aryl hydrocarbon receptor	target
Hesperetin	Microsomal triglyceride transfer protein large subunit	target
Hesperetin	Sterol O-acyltransferase 1	target
Hesperetin	Sterol O-acyltransferase 2	target
Hesperetin	Cytochrome P450 1A2	enzyme
Hesperetin	ATP-binding cassette sub-family G member 2	transporter
Hesperetin	Sex hormone-binding globulin	target
Genistein	Estrogen receptor beta	target
Genistein	DNA topoisomerase 2-alpha	target
Genistein	Protein-tyrosine kinase 2-beta	target
Genistein	P-glycoprotein 1	transporter
Genistein	Multidrug resistance-associated protein 1	transporter
Genistein	ATP-binding cassette sub-family G member 2	transporter
Genistein	Cytochrome P450 1A2	enzyme
Genistein	Nuclear receptor coactivator 1	target
Genistein	Estrogen receptor alpha	target
Genistein	Nuclear receptor coactivator 2	target
Genistein	Transthyretin	carrier
Genistein	Steroid hormone receptor ERR2	target
Genistein	Steroid hormone receptor ERR1	target
Genistein	Nuclear receptor subfamily 1 group I member 2	target
Genistein	RAC-alpha serine/threonine-protein kinase	target
Genistein	G-protein coupled estrogen receptor 1	target
Genistein	Cytochrome P450 1B1	target
Genistein	Sex hormone-binding globulin	target
Genistein	Cytochrome P450 1A1	enzyme
Genistein	Solute carrier organic anion transporter family member 1B1	transporter
Genistein	Solute carrier organic anion transporter family member 2B1	transporter
Genistein	Cytochrome P450 2C8	enzyme
Genistein	Cytochrome P450 2C9	enzyme
Genistein	Cytochrome P450 3A1	enzyme
Genistein	Cytochrome P450 3A2	enzyme
Genistein	Cytochrome P450 3A4	enzyme
Nelfinavir	HIV-1 protease	target
Nelfinavir	Cytochrome P450 2C19	enzyme
Nelfinavir	Cytochrome P450 3A4	enzyme
Nelfinavir	Cytochrome P450 2B6	enzyme
Nelfinavir	Cytochrome P450 3A5	enzyme
Nelfinavir	Cytochrome P450 3A7	enzyme
Nelfinavir	P-glycoprotein 1	transporter
Nelfinavir	Solute carrier family 22 member 1	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1A2	transporter
Nelfinavir	ATP-binding cassette sub-family G member 2	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1B1	transporter
Nelfinavir	Cytochrome P450 2D6	enzyme
Nelfinavir	Serum albumin	carrier
Nelfinavir	UDP-glucuronosyltransferase 1-1	enzyme
Nelfinavir	Solute carrier organic anion transporter family member 1B3	transporter
Nelfinavir	Solute carrier organic anion transporter family member 2B1	transporter
Nelfinavir	Bile salt export pump	transporter
Nelfinavir	Cytochrome P450 2C9	enzyme
Diethylstilbestrol	Estrogen receptor alpha	target
Diethylstilbestrol	Estrogen-related receptor gamma	target
Diethylstilbestrol	Transthyretin	carrier
Diethylstilbestrol	Catechol O-methyltransferase	enzyme
Diethylstilbestrol	Cytochrome P450 19A1	enzyme
Diethylstilbestrol	ATP-binding cassette sub-family G member 2	transporter
Diethylstilbestrol	P-glycoprotein 1	transporter
Diethylstilbestrol	Estrogen receptor beta	target
Diethylstilbestrol	Cytochrome P450 3A4	enzyme
Diethylstilbestrol	Cytochrome P450 2C8	enzyme
Diethylstilbestrol	Cytochrome P450 2C9	enzyme
Diethylstilbestrol	Cytochrome P450 2E1	enzyme
Diethylstilbestrol	Steroid hormone receptor ERR1	target
Diethylstilbestrol	Steroid hormone receptor ERR2	target
Diethylstilbestrol	Nuclear receptor coactivator 2	target
Diethylstilbestrol	Nuclear receptor subfamily 1 group I member 2	target
Diethylstilbestrol	Androgen receptor	target
Diethylstilbestrol	Sex hormone-binding globulin	target
Diethylstilbestrol	Solute carrier organic anion transporter family member 1B1	transporter
Diethylstilbestrol	Solute carrier organic anion transporter family member 2B1	transporter
Diethylstilbestrol	Bile salt export pump	transporter
Ritonavir	Human immunodeficiency virus type 1 protease	target
Ritonavir	Cytochrome P450 2D6	enzyme
Ritonavir	Cytochrome P450 2C9	enzyme
Ritonavir	Cytochrome P450 2C19	enzyme
Ritonavir	Cytochrome P450 2B6	enzyme
Ritonavir	Cytochrome P450 2C8	enzyme
Ritonavir	P-glycoprotein 1	transporter
Ritonavir	Multidrug resistance-associated protein 1	transporter
Ritonavir	Canalicular multispecific organic anion transporter 1	transporter
Ritonavir	Solute carrier organic anion transporter family member 1A2	transporter
Ritonavir	ATP-binding cassette sub-family G member 2	transporter
Ritonavir	Solute carrier organic anion transporter family member 1B1	transporter
Ritonavir	Cytochrome P450 1A2	enzyme
Ritonavir	Nuclear receptor subfamily 1 group I member 2	target
Ritonavir	Serum albumin	carrier
Ritonavir	Cytochrome P450 3A4	enzyme
Ritonavir	Cytochrome P450 3A5	enzyme
Ritonavir	Cytochrome P450 3A7	enzyme
Ritonavir	UDP-glucuronosyltransferases (UGTs)	enzyme
Ritonavir	Solute carrier organic anion transporter family member 2B1	transporter
Ritonavir	Bile salt export pump	transporter
Ritonavir	Alpha-1-acid glycoprotein 1	carrier
Ritonavir	Solute carrier organic anion transporter family member 1B3	transporter
Pantoprazole	Potassium-transporting ATPase alpha chain 1	target
Pantoprazole	Cytochrome P450 2C19	enzyme
Pantoprazole	Cytochrome P450 3A4	enzyme
Pantoprazole	P-glycoprotein 1	transporter
Pantoprazole	ATP-binding cassette sub-family G member 2	transporter
Pantoprazole	Solute carrier family 22 member 8	transporter
Pantoprazole	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	target
Cyclosporine	Calcium signal-modulating cyclophilin ligand	target
Cyclosporine	Peptidyl-prolyl cis-trans isomerase A	target
Cyclosporine	Calcineurin subunit B type 2	target
Cyclosporine	Cytochrome P450 3A5	enzyme
Cyclosporine	Cytochrome P450 3A4	enzyme
Cyclosporine	P-glycoprotein 1	transporter
Cyclosporine	Bile salt export pump	transporter
Cyclosporine	Ileal sodium/bile acid cotransporter	transporter
Cyclosporine	Sodium/bile acid cotransporter	transporter
Cyclosporine	Solute carrier family 22 member 6	transporter
Cyclosporine	Multidrug resistance-associated protein 7	transporter
Cyclosporine	Canalicular multispecific organic anion transporter 1	transporter
Cyclosporine	ATP-binding cassette sub-family G member 2	transporter
Cyclosporine	Solute carrier organic anion transporter family member 1B1	transporter
Cyclosporine	Cytochrome P450 2C19	enzyme
Cyclosporine	Cytochrome P450 2D6	enzyme
Cyclosporine	Peptidyl-prolyl cis-trans isomerase F, mitochondrial	target
Cyclosporine	Solute carrier organic anion transporter family member 1B3	transporter
Taurocholic acid	Bile salt-activated lipase	target
Taurocholic acid	Gastrotropin	target
Taurocholic acid	Bile salt export pump	transporter
Taurocholic acid	Multidrug resistance-associated protein 1	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1A2	transporter
Taurocholic acid	Ileal sodium/bile acid cotransporter	transporter
Taurocholic acid	Canalicular multispecific organic anion transporter 1	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1B1	transporter
Taurocholic acid	Canalicular multispecific organic anion transporter 2	transporter
Taurocholic acid	Multidrug resistance-associated protein 4	transporter
Taurocholic acid	P-glycoprotein 1	transporter
Taurocholic acid	Solute carrier family 22 member 6	transporter
Taurocholic acid	Multidrug resistance-associated protein 7	transporter
Taurocholic acid	Solute carrier family 22 member 8	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 4A1	transporter
Taurocholic acid	ATP-binding cassette sub-family C member 11	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1C1	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 3A1	transporter
Taurocholic acid	ATP-binding cassette sub-family G member 2	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 2B1	transporter
Taurocholic acid	Monocarboxylate transporter 1	transporter
Taurocholic acid	Sodium/bile acid cotransporter	transporter
Taurocholic acid	Organic solute transporter subunit alpha	transporter
Taurocholic acid	Organic solute transporter subunit beta	transporter
Taurocholic acid	Solute carrier organic anion transporter family member 1B3	transporter
Taurocholic acid	Cystine/glutamate transporter	transporter
Taurocholic acid	Bile acid receptor	target
Imatinib	Platelet-derived growth factor receptor beta	target
Imatinib	Tyrosine-protein kinase ABL1	target
Imatinib	Mast/stem cell growth factor receptor Kit	target
Imatinib	RET proto-oncogene	target
Imatinib	High affinity nerve growth factor receptor	target
Imatinib	Macrophage colony-stimulating factor 1 receptor	target
Imatinib	Platelet-derived growth factor receptor alpha	target
Imatinib	Epithelial discoidin domain-containing receptor 1	target
Imatinib	Cytochrome P450 3A4	enzyme
Imatinib	Breakpoint cluster region protein	target
Imatinib	Cytochrome P450 1A2	enzyme
Imatinib	Cytochrome P450 2D6	enzyme
Imatinib	Cytochrome P450 2C9	enzyme
Imatinib	Cytochrome P450 2C19	enzyme
Imatinib	Cytochrome P450 3A5	enzyme
Imatinib	Cytochrome P450 3A7	enzyme
Imatinib	Solute carrier family 22 member 1	transporter
Imatinib	P-glycoprotein 1	transporter
Imatinib	Solute carrier family 22 member 2	transporter
Imatinib	ATP-binding cassette sub-family G member 2	transporter
Imatinib	ATP-binding cassette sub-family A member 3	transporter
Imatinib	Prostaglandin G/H synthase 1	enzyme
Imatinib	Serum albumin	carrier
Imatinib	Alpha-1-acid glycoprotein 1	carrier
Imatinib	Bile salt export pump	transporter
Imatinib	Cytochrome P450 2C8	enzyme
Estradiol	Estrogen receptor alpha	target
Estradiol	Nuclear receptor subfamily 1 group I member 2	target
Estradiol	Sex hormone-binding globulin	carrier
Estradiol	Estrogen receptor beta	target
Estradiol	Cytochrome P450 1A2	enzyme
Estradiol	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol	Serum albumin	carrier
Estradiol	Fatty acid-binding protein, intestinal	carrier
Estradiol	Cytochrome P450 3A4	enzyme
Estradiol	Cytochrome P450 3A5	enzyme
Estradiol	Cytochrome P450 3A7	enzyme
Estradiol	Solute carrier family 22 member 2	transporter
Estradiol	Solute carrier family 22 member 3	transporter
Estradiol	Multidrug resistance-associated protein 7	transporter
Estradiol	Solute carrier family 22 member 11	transporter
Estradiol	ATP-binding cassette sub-family G member 2	transporter
Estradiol	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol	P-glycoprotein 1	transporter
Estradiol	Cytochrome P450 1A1	enzyme
Estradiol	Cytochrome P450 1B1	enzyme
Estradiol	Cytochrome P450 2C19	enzyme
Estradiol	Cytochrome P450 2C8	enzyme
Estradiol	Cytochrome P450 2C9	enzyme
Estradiol	Solute carrier family 22 member 8	transporter
Estradiol	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol	G-protein coupled estrogen receptor 1	target
Estradiol	ATP synthase subunit a	target
Estradiol	Beclin-1	target
Estradiol	UDP-glucuronosyltransferase 2B15	enzyme
Estradiol	Catechol O-methyltransferase	enzyme
Estradiol	UDP-glucuronosyltransferases (UGTs)	enzyme
Daidzin	Aldehyde dehydrogenase, mitochondrial	target
Daidzin	ATP-binding cassette sub-family G member 2	transporter
Sorafenib	Serine/threonine-protein kinase B-raf	target
Sorafenib	Receptor-type tyrosine-protein kinase FLT3	target
Sorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Sorafenib	Vascular endothelial growth factor receptor 3	target
Sorafenib	Platelet-derived growth factor receptor beta	target
Sorafenib	Mast/stem cell growth factor receptor Kit	target
Sorafenib	Vascular endothelial growth factor receptor 2	target
Sorafenib	Cytochrome P450 3A4	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-9	enzyme
Sorafenib	Cytochrome P450 2B6	enzyme
Sorafenib	Cytochrome P450 2C8	enzyme
Sorafenib	Cytochrome P450 3A5	enzyme
Sorafenib	Cytochrome P450 3A7	enzyme
Sorafenib	Cytochrome P450 2C9	enzyme
Sorafenib	Multidrug resistance-associated protein 4	transporter
Sorafenib	P-glycoprotein 1	transporter
Sorafenib	Canalicular multispecific organic anion transporter 1	transporter
Sorafenib	ATP-binding cassette sub-family G member 2	transporter
Sorafenib	Cytochrome P450 1A2	enzyme
Sorafenib	Cytochrome P450 2C19	enzyme
Sorafenib	Cytochrome P450 2D6	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Sorafenib	RalA-binding protein 1	transporter
Sorafenib	Fibroblast growth factor receptor 1	target
Sorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Sorafenib	Vascular endothelial growth factor receptor 1	target
Sorafenib	Solute carrier organic anion transporter family member 1B1	transporter
Sunitinib	Platelet-derived growth factor receptor beta	target
Sunitinib	Vascular endothelial growth factor receptor 1	target
Sunitinib	Vascular endothelial growth factor receptor 2	target
Sunitinib	Vascular endothelial growth factor receptor 3	target
Sunitinib	Mast/stem cell growth factor receptor Kit	target
Sunitinib	Receptor-type tyrosine-protein kinase FLT3	target
Sunitinib	Macrophage colony-stimulating factor 1 receptor	target
Sunitinib	Platelet-derived growth factor receptor alpha	target
Sunitinib	Cytochrome P450 3A4	enzyme
Sunitinib	Cytochrome P450 3A5	enzyme
Sunitinib	Cytochrome P450 3A7	enzyme
Sunitinib	Multidrug resistance-associated protein 4	transporter
Sunitinib	P-glycoprotein 1	transporter
Sunitinib	Canalicular multispecific organic anion transporter 1	transporter
Sunitinib	ATP-binding cassette sub-family G member 2	transporter
Dronabinol	Cannabinoid receptor 1	target
Dronabinol	Cytochrome P450 3A4	enzyme
Dronabinol	Cytochrome P450 2C9	enzyme
Dronabinol	Cannabinoid receptor 2	target
Dronabinol	P-glycoprotein 1	transporter
Dronabinol	ATP-binding cassette sub-family G member 2	transporter
Dronabinol	Prostaglandin G/H synthase 1	enzyme
Buprenorphine	Kappa-type opioid receptor	target
Buprenorphine	Mu-type opioid receptor	target
Buprenorphine	Cytochrome P450 3A4	enzyme
Buprenorphine	Cytochrome P450 2D6	enzyme
Buprenorphine	P-glycoprotein 1	transporter
Buprenorphine	ATP-binding cassette sub-family G member 2	transporter
Buprenorphine	Cytochrome P450 2C9	enzyme
Buprenorphine	Cytochrome P450 3A5	enzyme
Buprenorphine	Cytochrome P450 2C8	enzyme
Buprenorphine	Cytochrome P450 3A7	enzyme
Buprenorphine	Delta-type opioid receptor	target
Buprenorphine	Cytochrome P450 2C18	enzyme
Buprenorphine	Cytochrome P450 2C19	enzyme
Buprenorphine	Nociceptin receptor	target
Sulfasalazine	Acetyl-CoA acetyltransferase, mitochondrial	target
Sulfasalazine	Cystine/glutamate transporter	target
Sulfasalazine	ATP-binding cassette sub-family G member 2	transporter
Sulfasalazine	Canalicular multispecific organic anion transporter 1	transporter
Sulfasalazine	Inhibitor of nuclear factor kappa-B kinase subunit alpha	target
Sulfasalazine	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
Sulfasalazine	Prostaglandin G/H synthase 2	target
Sulfasalazine	Peroxisome proliferator-activated receptor gamma	target
Sulfasalazine	Prostaglandin G/H synthase 1	target
Sulfasalazine	Arachidonate 5-lipoxygenase	target
Sulfasalazine	Proton-coupled folate transporter	transporter
Sulfasalazine	Thromboxane-A synthase	target
Sulfasalazine	Phospholipase A2	target
Sulfasalazine	Solute carrier organic anion transporter family member 1B1	transporter
Sulfasalazine	Solute carrier organic anion transporter family member 1B3	transporter
Sulfasalazine	Solute carrier organic anion transporter family member 2B1	transporter
Telmisartan	Type-1 angiotensin II receptor	target
Telmisartan	Peroxisome proliferator-activated receptor gamma	target
Telmisartan	P-glycoprotein 1	transporter
Telmisartan	Canalicular multispecific organic anion transporter 1	transporter
Telmisartan	ATP-binding cassette sub-family G member 2	transporter
Telmisartan	Cytochrome P450 2C19	enzyme
Telmisartan	Bile salt export pump	transporter
Telmisartan	UDP-glucuronosyltransferase 1-3	enzyme
Dexamethasone	Glucocorticoid receptor	target
Dexamethasone	Annexin A1	target
Dexamethasone	Nitric oxide synthase, inducible	target
Dexamethasone	Nuclear receptor subfamily 0 group B member 1	target
Dexamethasone	Cytochrome P450 3A4	enzyme
Dexamethasone	Cytochrome P450 3A5	enzyme
Dexamethasone	Cytochrome P450 3A7	enzyme
Dexamethasone	Bile salt export pump	transporter
Dexamethasone	P-glycoprotein 1	transporter
Dexamethasone	Canalicular multispecific organic anion transporter 1	transporter
Dexamethasone	Solute carrier organic anion transporter family member 1A2	transporter
Dexamethasone	ATP-binding cassette sub-family G member 2	transporter
Dexamethasone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Dexamethasone	Cytochrome P450 1A1	enzyme
Dexamethasone	Cytochrome P450 2A6	enzyme
Dexamethasone	Cytochrome P450 2B6	enzyme
Dexamethasone	Cytochrome P450 2C19	enzyme
Dexamethasone	Cytochrome P450 2C8	enzyme
Dexamethasone	Cytochrome P450 2E1	enzyme
Dexamethasone	Cytochrome P450 3A43	enzyme
Dexamethasone	Cytochrome P450 4A11	enzyme
Dexamethasone	Nuclear receptor subfamily 1 group I member 2	target
Dexamethasone	Cytochrome P450 11B1, mitochondrial	enzyme
Dexamethasone	Serum albumin	carrier
Dexamethasone	Corticosteroid 11-beta-dehydrogenase isozyme 2	enzyme
Dexamethasone	Corticosteroid 11-beta-dehydrogenase isozyme 1	enzyme
Dexamethasone	Solute carrier family 22 member 8	transporter
Dasatinib	Tyrosine-protein kinase ABL1	target
Dasatinib	Abelson tyrosine-protein kinase 2	target
Dasatinib	Proto-oncogene tyrosine-protein kinase Src	target
Dasatinib	Tyrosine-protein kinase Fyn	target
Dasatinib	Tyrosine-protein kinase Lck	target
Dasatinib	Tyrosine-protein kinase Yes	target
Dasatinib	Mast/stem cell growth factor receptor Kit	target
Dasatinib	Platelet-derived growth factor receptor beta	target
Dasatinib	Ephrin type-A receptor 2	target
Dasatinib	Signal transducer and activator of transcription 5B	target
Dasatinib	Cytochrome P450 3A4	enzyme
Dasatinib	P-glycoprotein 1	transporter
Dasatinib	ATP-binding cassette sub-family G member 2	transporter
Dasatinib	Cytochrome P450 1A1	enzyme
Dasatinib	Cytochrome P450 1A2	enzyme
Dasatinib	Cytochrome P450 1B1	enzyme
Dasatinib	Cytochrome P450 3A5	enzyme
Dasatinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Dasatinib	Tyrosine-protein kinase BTK	target
Dasatinib	Nuclear receptor subfamily 4 group A member 3	target
Dasatinib	Breakpoint cluster region protein	target
Dasatinib	Tyrosine-protein kinase CSK	target
Dasatinib	Ephrin type-A receptor 5	target
Dasatinib	Ephrin type-B receptor 4	target
Dasatinib	Tyrosine-protein kinase Fgr	target
Dasatinib	Tyrosine-protein kinase FRK	target
Dasatinib	Heat shock cognate 71 kDa protein	target
Dasatinib	Tyrosine-protein kinase Lyn	target
Dasatinib	Mitogen-activated protein kinase kinase kinase MLT	target
Dasatinib	Mitogen-activated protein kinase 14	target
Dasatinib	Amidophosphoribosyltransferase	target
Rabeprazole	Potassium-transporting ATPase alpha chain 1	target
Rabeprazole	Cytochrome P450 3A4	enzyme
Rabeprazole	Cytochrome P450 2C19	enzyme
Rabeprazole	ATP-binding cassette sub-family G member 2	transporter
Rabeprazole	Cytochrome P450 1A1	enzyme
Rabeprazole	Cytochrome P450 1A2	enzyme
Rabeprazole	Cytochrome P450 2C9	enzyme
Rabeprazole	Cytochrome P450 2D6	enzyme
Rabeprazole	Cytochrome P450 2C8	enzyme
Elacridar	P-glycoprotein 1	target
Elacridar	ATP-binding cassette sub-family G member 2	transporter
Elacridar	P-glycoprotein 1	transporter
Nilotinib	Tyrosine-protein kinase ABL1	target
Nilotinib	Mast/stem cell growth factor receptor Kit	target
Nilotinib	Cytochrome P450 2D6	enzyme
Nilotinib	Cytochrome P450 2C8	enzyme
Nilotinib	Cytochrome P450 2C9	enzyme
Nilotinib	Cytochrome P450 3A4	enzyme
Nilotinib	P-glycoprotein 1	transporter
Nilotinib	ATP-binding cassette sub-family G member 2	transporter
Nilotinib	UDP-glucuronosyltransferase 1-1	transporter
Nilotinib	Cytochrome P450 2B6	enzyme
Nilotinib	Solute carrier organic anion transporter family member 1B1	transporter
Erlotinib	Epidermal growth factor receptor	target
Erlotinib	Cytochrome P450 3A4	enzyme
Erlotinib	ATP-binding cassette sub-family G member 2	transporter
Erlotinib	P-glycoprotein 1	transporter
Erlotinib	Nuclear receptor subfamily 1 group I member 2	target
Erlotinib	Cytochrome P450 3A5	enzyme
Erlotinib	Cytochrome P450 1A1	enzyme
Erlotinib	Cytochrome P450 1A2	enzyme
Erlotinib	Cytochrome P450 1B1	enzyme
Erlotinib	Cytochrome P450 2D6	enzyme
Erlotinib	Cytochrome P450 2C8	enzyme
Erlotinib	UDP-glucuronosyltransferase 1-1	enzyme
Erlotinib	Serum albumin	carrier
Erlotinib	Alpha-1-acid glycoprotein 1	carrier
Erlotinib	Solute carrier organic anion transporter family member 2B1	transporter
Vandetanib	Vascular endothelial growth factor A	target
Vandetanib	Epidermal growth factor receptor	target
Vandetanib	Multidrug resistance-associated protein 1	transporter
Vandetanib	ATP-binding cassette sub-family G member 2	transporter
Vandetanib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Vandetanib	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Vandetanib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Vandetanib	Protein-tyrosine kinase 6	target
Vandetanib	Angiopoietin-1 receptor	target
Vandetanib	Alpha-1-acid glycoprotein 1	carrier
Vandetanib	Serum albumin	carrier
Vandetanib	Cytochrome P450 3A4	enzyme
Vandetanib	Solute carrier family 22 member 2	transporter
Vandetanib	P-glycoprotein 1	transporter
Cabazitaxel	Cytochrome P450 3A4	enzyme
Cabazitaxel	Cytochrome P450 3A5	enzyme
Cabazitaxel	Cytochrome P450 2C8	enzyme
Cabazitaxel	P-glycoprotein 1	transporter
Cabazitaxel	ATP-binding cassette sub-family G member 2	transporter
Cabazitaxel	Tubulin alpha-4A chain	target
Cabazitaxel	Tubulin beta-1 chain	target
Cabazitaxel	Solute carrier organic anion transporter family member 1B1	transporter
Cabazitaxel	Solute carrier organic anion transporter family member 1B3	transporter
Rilpivirine	Cytochrome P450 3A4	enzyme
Rilpivirine	Reverse transcriptase/RNaseH	target
Rilpivirine	Nuclear receptor subfamily 1 group I member 2	target
Rilpivirine	Cytochrome P450 2C19	enzyme
Rilpivirine	Cytochrome P450 2B6	enzyme
Rilpivirine	P-glycoprotein 1	transporter
Rilpivirine	ATP-binding cassette sub-family G member 2	transporter
Rilpivirine	Solute carrier organic anion transporter family member 1B1	transporter
Rilpivirine	Solute carrier organic anion transporter family member 1B3	transporter
Rilpivirine	Serum albumin	carrier
Rilpivirine	Cytochrome P450 2D6	enzyme
Vismodegib	Smoothened homolog	target
Vismodegib	Cytochrome P450 2C9	enzyme
Vismodegib	Cytochrome P450 3A4	enzyme
Vismodegib	P-glycoprotein 1	transporter
Vismodegib	Cytochrome P450 2C8	enzyme
Vismodegib	Cytochrome P450 2C19	enzyme
Vismodegib	ATP-binding cassette sub-family G member 2	transporter
Vismodegib	Serum albumin	carrier
Vismodegib	Alpha-1-acid glycoprotein 1	carrier
Regorafenib	Cytochrome P450 3A4	enzyme
Regorafenib	UDP-glucuronosyltransferase 1-9	enzyme
Regorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Regorafenib	Vascular endothelial growth factor receptor 1	target
Regorafenib	Vascular endothelial growth factor receptor 2	target
Regorafenib	Vascular endothelial growth factor receptor 3	target
Regorafenib	Mast/stem cell growth factor receptor Kit	target
Regorafenib	Platelet-derived growth factor receptor alpha	target
Regorafenib	Platelet-derived growth factor receptor beta	target
Regorafenib	Fibroblast growth factor receptor 1	target
Regorafenib	Fibroblast growth factor receptor 2	target
Regorafenib	Angiopoietin-1 receptor	target
Regorafenib	Discoidin domain-containing receptor 2	target
Regorafenib	High affinity nerve growth factor receptor	target
Regorafenib	Ephrin type-A receptor 2	target
Regorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Regorafenib	Serine/threonine-protein kinase B-raf	target
Regorafenib	Cytochrome P450 2C8	enzyme
Regorafenib	Cytochrome P450 2C9	enzyme
Regorafenib	Cytochrome P450 2B6	enzyme
Regorafenib	Mitogen-activated protein kinase 11	target
Regorafenib	Tyrosine-protein kinase FRK	target
Regorafenib	Tyrosine-protein kinase ABL1	target
Regorafenib	P-glycoprotein 1	transporter
Regorafenib	ATP-binding cassette sub-family G member 2	transporter
Regorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Ponatinib	Tyrosine-protein kinase ABL1	target
Ponatinib	Breakpoint cluster region protein	target
Ponatinib	Mast/stem cell growth factor receptor Kit	target
Ponatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Ponatinib	Angiopoietin-1 receptor	target
Ponatinib	Receptor-type tyrosine-protein kinase FLT3	target
Ponatinib	Cytochrome P450 3A4	enzyme
Ponatinib	Cytochrome P450 2C8	enzyme
Ponatinib	Cytochrome P450 2D6	enzyme
Ponatinib	Cytochrome P450 3A5	enzyme
Ponatinib	P-glycoprotein 1	transporter
Ponatinib	ATP-binding cassette sub-family G member 2	transporter
Ponatinib	Fibroblast growth factor receptor 1	target
Ponatinib	Fibroblast growth factor receptor 2	target
Ponatinib	Fibroblast growth factor receptor 3	target
Ponatinib	Fibroblast growth factor receptor 4	target
Ponatinib	Tyrosine-protein kinase Lck	target
Ponatinib	Proto-oncogene tyrosine-protein kinase Src	target
Ponatinib	Tyrosine-protein kinase Lyn	target
Ponatinib	Vascular endothelial growth factor receptor 2	target
Ponatinib	Platelet-derived growth factor receptor alpha	target
Dabrafenib	Cytochrome P450 3A4	enzyme
Dabrafenib	Cytochrome P450 2C8	enzyme
Dabrafenib	P-glycoprotein 1	transporter
Dabrafenib	ATP-binding cassette sub-family G member 2	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B1	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B3	transporter
Dabrafenib	Solute carrier family 22 member 6	transporter
Dabrafenib	Solute carrier family 22 member 8	transporter
Dabrafenib	Serine/threonine-protein kinase B-raf	target
Dabrafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Dabrafenib	Serine/threonine-protein kinase SIK1	target
Dabrafenib	Serine/threonine-protein kinase Nek11	target
Dabrafenib	LIM domain kinase 1	target
Dabrafenib	Cytochrome P450 2B6	enzyme
Dabrafenib	Cytochrome P450 2C9	enzyme
Dabrafenib	Cytochrome P450 2C19	enzyme
Dabrafenib	Cytochrome P450 1A2	enzyme
Afatinib	Epidermal growth factor receptor	target
Afatinib	Receptor tyrosine-protein kinase erbB-2	target
Afatinib	Receptor tyrosine-protein kinase erbB-4	target
Afatinib	P-glycoprotein 1	transporter
Afatinib	ATP-binding cassette sub-family G member 2	transporter
Cobicistat	Cytochrome P450 2D6	enzyme
Cobicistat	P-glycoprotein 1	transporter
Cobicistat	ATP-binding cassette sub-family G member 2	transporter
Cobicistat	Cytochrome P450 3A4	enzyme
Cobicistat	Cytochrome P450 3A5	enzyme
Cobicistat	Cytochrome P450 3A7	enzyme
Cobicistat	Cytochrome P450 3A43	enzyme
Cobicistat	Solute carrier organic anion transporter family member 1B1	transporter
Cobicistat	Solute carrier organic anion transporter family member 1B3	transporter
Rolapitant	Neurokinin 1 receptor	target
Rolapitant	Cytochrome P450 2D6	enzyme
Rolapitant	Cytochrome P450 3A4	enzyme
Rolapitant	ATP-binding cassette sub-family G member 2	transporter
Rolapitant	P-glycoprotein 1	transporter
Daclatasvir	Nonstructural protein 5A	target
Daclatasvir	Cytochrome P450 3A5	enzyme
Daclatasvir	Cytochrome P450 3A4	enzyme
Daclatasvir	Cytochrome P450 3A43	enzyme
Daclatasvir	Cytochrome P450 3A7	enzyme
Daclatasvir	P-glycoprotein 1	transporter
Daclatasvir	Solute carrier organic anion transporter family member 1B1	transporter
Daclatasvir	Solute carrier organic anion transporter family member 1B3	transporter
Daclatasvir	ATP-binding cassette sub-family G member 2	transporter
Alectinib	ALK tyrosine kinase receptor	target
Alectinib	ATP-binding cassette sub-family G member 2	transporter
Alectinib	P-glycoprotein 1	transporter
Dasabuvir	Nonstructural protein 5B (NS5B)	target
Dasabuvir	Cytochrome P450 2C8	enzyme
Dasabuvir	Cytochrome P450 3A4	enzyme
Dasabuvir	Cytochrome P450 2D6	enzyme
Dasabuvir	UDP-glucuronosyltransferase 1-1	enzyme
Dasabuvir	ATP-binding cassette sub-family G member 2	transporter
Dasabuvir	ATP-binding cassette sub-family B member 5	transporter
Dasabuvir	P-glycoprotein 1	transporter
Velpatasvir	Cytochrome P450 2B6	enzyme
Velpatasvir	Cytochrome P450 2C8	enzyme
Velpatasvir	Cytochrome P450 3A4	enzyme
Velpatasvir	Nonstructural protein 5A	target
Velpatasvir	P-glycoprotein 1	transporter
Velpatasvir	ATP-binding cassette sub-family G member 2	transporter
Velpatasvir	Solute carrier organic anion transporter family member 1B1	transporter
Velpatasvir	Solute carrier organic anion transporter family member 1B3	transporter
Velpatasvir	Solute carrier organic anion transporter family member 2B1	transporter
Simeprevir	NS3 protease	target
Simeprevir	Serum albumin	carrier
Simeprevir	Cytochrome P450 1A2	enzyme
Simeprevir	P-glycoprotein 1	transporter
Simeprevir	Solute carrier organic anion transporter family member 1B1	transporter
Simeprevir	Solute carrier organic anion transporter family member 1B3	transporter
Simeprevir	Cytochrome P450 3A4	enzyme
Simeprevir	Canalicular multispecific organic anion transporter 1	transporter
Simeprevir	ATP-binding cassette sub-family G member 2	transporter
Simeprevir	Solute carrier organic anion transporter family member 2B1	transporter
Simeprevir	Sodium/bile acid cotransporter	transporter
Simeprevir	Bile salt export pump	transporter
Topiroxostat	Xanthine dehydrogenase/oxidase	target
Topiroxostat	ATP-binding cassette sub-family G member 2	transporter
Topiroxostat	Serum albumin	carrier
Topiroxostat	Alpha-1-acid glycoprotein 1	carrier
Topiroxostat	Cytochrome P450 2C8	enzyme
Topiroxostat	Cytochrome P450 2C9	enzyme
Topiroxostat	Cytochrome P450 1A1	enzyme
Topiroxostat	Cytochrome P450 3A4	enzyme
Topiroxostat	Cytochrome P450 2C19	enzyme
Topiroxostat	Solute carrier family 22 member 8	transporter
Topiroxostat	Solute carrier family 22 member 6	transporter
Topiroxostat	UDP-glucuronosyltransferase 1-9	enzyme
Voxilaprevir	Cytochrome P450 3A4	enzyme
Voxilaprevir	Cytochrome P450 1A2	enzyme
Voxilaprevir	Cytochrome P450 2C8	enzyme
Voxilaprevir	NS3/4A protein	target
Voxilaprevir	P-glycoprotein 1	transporter
Voxilaprevir	ATP-binding cassette sub-family G member 2	transporter
Voxilaprevir	Solute carrier organic anion transporter family member 1B1	transporter
Voxilaprevir	Solute carrier organic anion transporter family member 1B3	transporter
Enasidenib	Cytochrome P450 1A2	enzyme
Enasidenib	Cytochrome P450 2B6	enzyme
Enasidenib	Isocitrate dehydrogenase [NADP], mitochondrial	target
Enasidenib	Cytochrome P450 2C8	enzyme
Enasidenib	Cytochrome P450 2C9	enzyme
Enasidenib	Cytochrome P450 2C19	enzyme
Enasidenib	Cytochrome P450 2D6	enzyme
Enasidenib	Cytochrome P450 3A4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-1	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-3	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-9	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B7	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B15	enzyme
Enasidenib	P-glycoprotein 1	transporter
Enasidenib	ATP-binding cassette sub-family G member 2	transporter
Enasidenib	Solute carrier family 22 member 6	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B1	transporter
Enasidenib	Solute carrier family 22 member 2	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B3	transporter
Enasidenib	Solute carrier family 22 member 8	transporter
Pibrentasvir	Nonstructural protein 5A	target
Pibrentasvir	Cytochrome P450 3A Subfamily	enzyme
Pibrentasvir	UDP-glucuronosyltransferase 1-1	enzyme
Pibrentasvir	P-glycoprotein 1	transporter
Pibrentasvir	ATP-binding cassette sub-family G member 2	transporter
Pibrentasvir	Solute carrier organic anion transporter family member 1B1	transporter
Pibrentasvir	Solute carrier organic anion transporter family member 1B3	transporter
Glecaprevir	Cytochrome P450 3A Subfamily	enzyme
Glecaprevir	UDP-glucuronosyltransferase 1-1	enzyme
Glecaprevir	P-glycoprotein 1	transporter
Glecaprevir	ATP-binding cassette sub-family G member 2	transporter
Glecaprevir	Solute carrier organic anion transporter family member 1B1	transporter
Glecaprevir	Solute carrier organic anion transporter family member 1B3	transporter
Glecaprevir	NS3 protease	target
Glecaprevir	Cytochrome P450 3A4	enzyme
Abemaciclib	Multidrug and toxin extrusion protein 1	transporter
Abemaciclib	Multidrug and toxin extrusion protein 2	transporter
Abemaciclib	Cyclin-dependent kinase 4	target
Abemaciclib	Cyclin-dependent kinase 6	target
Abemaciclib	Serum albumin	carrier
Abemaciclib	alpha1-acid glycoprotein	carrier
Abemaciclib	Cytochrome P450 3A4	enzyme
Abemaciclib	P-glycoprotein 1	transporter
Abemaciclib	ATP-binding cassette sub-family G member 2	transporter
Abemaciclib	Solute carrier family 22 member 2	transporter
Abemaciclib	Cytochrome P450 1A2	enzyme
Abemaciclib	Cytochrome P450 2B6	enzyme
Abemaciclib	Cytochrome P450 2C8	enzyme
Abemaciclib	Cytochrome P450 2C9	enzyme
Abemaciclib	Cytochrome P450 2D6	enzyme
Letermovir	UDP-glucuronosyltransferase 1-1	enzyme
Letermovir	UDP-glucuronosyltransferase 1-3	enzyme
Letermovir	Solute carrier organic anion transporter family member 1B1	transporter
Letermovir	Solute carrier organic anion transporter family member 1B3	transporter
Letermovir	Tripartite terminase subunit 1	target
Letermovir	Tripartite terminase subunit 2	target
Letermovir	Tripartite terminase subunit 3	target
Letermovir	Cytochrome P450 2D6	enzyme
Letermovir	Cytochrome P450 2C8	enzyme
Letermovir	Cytochrome P450 2C19	enzyme
Letermovir	Cytochrome P450 2C9	enzyme
Letermovir	Cytochrome P450 2B6	enzyme
Letermovir	P-glycoprotein 1	transporter
Letermovir	ATP-binding cassette sub-family G member 2	transporter
Letermovir	Bile salt export pump	transporter
Letermovir	Solute carrier family 22 member 8	transporter
Letermovir	Canalicular multispecific organic anion transporter 1	transporter
Letermovir	Cytochrome P450 3A4	enzyme
Letermovir	Cytochrome P450 3A5	enzyme
Letermovir	Cytochrome P450 3A7	enzyme
Letermovir	Cytochrome P450 3A43	enzyme
Brigatinib	ALK tyrosine kinase receptor	target
Brigatinib	Epidermal growth factor receptor	target
Brigatinib	Tyrosine-protein kinase ABL1	target
Brigatinib	Insulin-like growth factor 1 receptor	target
Brigatinib	Receptor-type tyrosine-protein kinase FLT3	target
Brigatinib	Cytochrome P450 2C8	enzyme
Brigatinib	Cytochrome P450 3A4	enzyme
Brigatinib	Insulin receptor	target
Brigatinib	Hepatocyte growth factor receptor	target
Brigatinib	Receptor tyrosine-protein kinase erbB-4	target
Brigatinib	Receptor tyrosine-protein kinase erbB-2	target
Brigatinib	ATP-binding cassette sub-family B member 5	transporter
Brigatinib	ATP-binding cassette sub-family G member 2	transporter
Brigatinib	Solute carrier family 22 member 1	transporter
Brigatinib	Multidrug and toxin extrusion protein 1	transporter
Brigatinib	Multidrug and toxin extrusion protein 2	transporter
Brigatinib	Cytochrome P450 3A Subfamily	enzyme
Rucaparib	Poly [ADP-ribose] polymerase 1	target
Rucaparib	Poly [ADP-ribose] polymerase 2	target
Rucaparib	Poly [ADP-ribose] polymerase 3	target
Rucaparib	Cytochrome P450 2D6	enzyme
Rucaparib	Cytochrome P450 1A2	enzyme
Rucaparib	Cytochrome P450 3A4	enzyme
Rucaparib	P-glycoprotein 1	transporter
Rucaparib	ATP-binding cassette sub-family G member 2	transporter
Rucaparib	Multidrug and toxin extrusion protein 1	transporter
Rucaparib	Multidrug and toxin extrusion protein 2	transporter
Rucaparib	Solute carrier family 22 member 1	transporter
Rucaparib	Multidrug resistance-associated protein 4	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B1	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B3	transporter
Rucaparib	Solute carrier family 22 member 6	transporter
Rucaparib	Solute carrier family 22 member 8	transporter
Rucaparib	Cytochrome P450 3A5	enzyme
Rucaparib	Cytochrome P450 3A7	enzyme
Rucaparib	Cytochrome P450 3A43	enzyme
Rucaparib	Cytochrome P450 2C19	enzyme
Rucaparib	Cytochrome P450 2C9	enzyme
Rucaparib	Cytochrome P450 2C8	enzyme
Rucaparib	UDP-glucuronosyltransferase 1-1	enzyme
Baricitinib	Solute carrier family 22 member 8	transporter
Baricitinib	ATP-binding cassette sub-family G member 2	transporter
Baricitinib	Multidrug and toxin extrusion protein 2	transporter
Baricitinib	Cytochrome P450 3A4	enzyme
Baricitinib	Tyrosine-protein kinase JAK1	target
Baricitinib	Tyrosine-protein kinase JAK2	target
Baricitinib	Solute carrier family 22 member 6	transporter
Baricitinib	Solute carrier family 22 member 2	transporter
Baricitinib	Solute carrier organic anion transporter family member 1B3	transporter
Baricitinib	Protein-tyrosine kinase 2-beta	target
Baricitinib	Tyrosine-protein kinase JAK3	target
Baricitinib	P-glycoprotein 1	transporter
Cannabidiol	Cytochrome P450 2C9	enzyme
Cannabidiol	Cytochrome P450 2C19	enzyme
Cannabidiol	Cytochrome P450 2D6	enzyme
Cannabidiol	Cytochrome P450 3A4	enzyme
Cannabidiol	Cannabinoid receptor 1	target
Cannabidiol	Cannabinoid receptor 2	target
Cannabidiol	G-protein coupled receptor 12	target
Cannabidiol	Glycine receptor subunit alpha-1	target
Cannabidiol	Glycine receptor (alpha-1/beta)	target
Cannabidiol	Glycine receptor subunit alpha-3	target
Cannabidiol	N-arachidonyl glycine receptor	target
Cannabidiol	G-protein coupled receptor 55	target
Cannabidiol	5-hydroxytryptamine receptor 1A	target
Cannabidiol	5-hydroxytryptamine receptor 2A	target
Cannabidiol	Neuronal acetylcholine receptor subunit alpha-7	target
Cannabidiol	Delta-type opioid receptor	target
Cannabidiol	Mu-type opioid receptor	target
Cannabidiol	Peroxisome proliferator-activated receptor gamma	target
Cannabidiol	Cytochrome P450 3A5	enzyme
Cannabidiol	Arylalkylamine N-acetyltransferase	enzyme
Cannabidiol	Cytochrome P450 1A1	enzyme
Cannabidiol	Fatty-acid amide hydrolase 1	enzyme
Cannabidiol	Arachidonate 5-lipoxygenase	enzyme
Cannabidiol	Arachidonate 15-lipoxygenase	enzyme
Cannabidiol	Quinone oxidoreductase	enzyme
Cannabidiol	Multidrug resistance-associated protein 1	transporter
Cannabidiol	ATP-binding cassette sub-family G member 2	transporter
Cannabidiol	Equilibrative nucleoside transporter 1	transporter
Cannabidiol	Transient receptor potential cation channel subfamily V member 1	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Cannabidiol	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Cannabidiol	Transient receptor potential cation channel subfamily A member 1	target
Cannabidiol	Transient receptor potential cation channel subfamily M member 8	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 2	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 3	target
Cannabidiol	Transient receptor potential cation channel subfamily V member 4	target
Cannabidiol	Voltage-dependent anion-selective channel protein 1	target
Cannabidiol	5-hydroxytryptamine receptor 3A	target
Cannabidiol	Adenosine receptor A1	target
Cannabidiol	Prostaglandin G/H synthase 1	target
Cannabidiol	Prostaglandin G/H synthase 2	target
Cannabidiol	Acetyl-CoA acetyltransferase, mitochondrial	target
Cannabidiol	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Cannabidiol	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Cannabidiol	Glutathione reductase, mitochondrial	target
Cannabidiol	Glutathione peroxidase 1	target
Cannabidiol	Indoleamine 2,3-dioxygenase 1	target
Cannabidiol	Cytochrome P450 1B1	target
Cannabidiol	NAD(P)H dehydrogenase [quinone] 1	target
Cannabidiol	Catalase	target
Cannabidiol	Cytochrome P450 3A5	target
Cannabidiol	Cytochrome P450 2D6	target
Cannabidiol	Superoxide dismutase [Cu-Zn]	target
Cannabidiol	Cytochrome P450 1A2	target
Cannabidiol	Cytochrome P450 3A7	target
Cannabidiol	Arylalkylamine N-acetyltransferase	target
Cannabidiol	N-acylethanolamine-hydrolyzing acid amidase	target
Estradiol acetate	Estrogen receptor alpha	target
Estradiol acetate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol acetate	Sex hormone-binding globulin	carrier
Estradiol acetate	Estrogen receptor beta	target
Estradiol acetate	Cytochrome P450 1A2	enzyme
Estradiol acetate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol acetate	Serum albumin	carrier
Estradiol acetate	Fatty acid-binding protein, intestinal	carrier
Estradiol acetate	Cytochrome P450 3A4	enzyme
Estradiol acetate	Cytochrome P450 3A5	enzyme
Estradiol acetate	Cytochrome P450 3A7	enzyme
Estradiol acetate	Solute carrier family 22 member 2	transporter
Estradiol acetate	Solute carrier family 22 member 1	transporter
Estradiol acetate	Solute carrier family 22 member 3	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol acetate	Multidrug resistance-associated protein 7	transporter
Estradiol acetate	Solute carrier family 22 member 11	transporter
Estradiol acetate	ATP-binding cassette sub-family G member 2	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol acetate	P-glycoprotein 1	transporter
Estradiol acetate	Cytochrome P450 1A1	enzyme
Estradiol acetate	Cytochrome P450 1B1	enzyme
Estradiol acetate	Cytochrome P450 2C19	enzyme
Estradiol acetate	Cytochrome P450 2C8	enzyme
Estradiol acetate	Cytochrome P450 2C9	enzyme
Estradiol acetate	Solute carrier family 22 member 8	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol acetate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol acetate	Nuclear receptor coactivator 2	target
Estradiol acetate	G-protein coupled estrogen receptor 1	target
Estradiol acetate	ATP synthase subunit a	target
Estradiol acetate	Beclin-1	target
Estradiol acetate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol acetate	Estrogen-related receptor gamma	target
Estradiol benzoate	Estrogen receptor alpha	target
Estradiol benzoate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol benzoate	Sex hormone-binding globulin	carrier
Estradiol benzoate	Estrogen receptor beta	target
Estradiol benzoate	Cytochrome P450 1A2	enzyme
Estradiol benzoate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol benzoate	Serum albumin	carrier
Estradiol benzoate	Fatty acid-binding protein, intestinal	carrier
Estradiol benzoate	Cytochrome P450 3A4	enzyme
Estradiol benzoate	Cytochrome P450 3A5	enzyme
Estradiol benzoate	Cytochrome P450 3A7	enzyme
Estradiol benzoate	Solute carrier family 22 member 2	transporter
Estradiol benzoate	Solute carrier family 22 member 1	transporter
Estradiol benzoate	Solute carrier family 22 member 3	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol benzoate	Multidrug resistance-associated protein 7	transporter
Estradiol benzoate	Solute carrier family 22 member 11	transporter
Estradiol benzoate	ATP-binding cassette sub-family G member 2	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol benzoate	P-glycoprotein 1	transporter
Estradiol benzoate	Cytochrome P450 1A1	enzyme
Estradiol benzoate	Cytochrome P450 1B1	enzyme
Estradiol benzoate	Cytochrome P450 2C19	enzyme
Estradiol benzoate	Cytochrome P450 2C8	enzyme
Estradiol benzoate	Cytochrome P450 2C9	enzyme
Estradiol benzoate	Solute carrier family 22 member 8	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol benzoate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol benzoate	Nuclear receptor coactivator 2	target
Estradiol benzoate	G-protein coupled estrogen receptor 1	target
Estradiol benzoate	ATP synthase subunit a	target
Estradiol benzoate	Beclin-1	target
Estradiol benzoate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol benzoate	Estrogen-related receptor gamma	target
Estradiol cypionate	Estrogen receptor alpha	target
Estradiol cypionate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol cypionate	Sex hormone-binding globulin	carrier
Estradiol cypionate	Estrogen receptor beta	target
Estradiol cypionate	Cytochrome P450 1A2	enzyme
Estradiol cypionate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol cypionate	Serum albumin	carrier
Estradiol cypionate	Fatty acid-binding protein, intestinal	carrier
Estradiol cypionate	Cytochrome P450 3A4	enzyme
Estradiol cypionate	Cytochrome P450 3A5	enzyme
Estradiol cypionate	Cytochrome P450 3A7	enzyme
Estradiol cypionate	Solute carrier family 22 member 2	transporter
Estradiol cypionate	Solute carrier family 22 member 1	transporter
Estradiol cypionate	Solute carrier family 22 member 3	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol cypionate	Multidrug resistance-associated protein 7	transporter
Estradiol cypionate	Solute carrier family 22 member 11	transporter
Estradiol cypionate	ATP-binding cassette sub-family G member 2	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol cypionate	P-glycoprotein 1	transporter
Estradiol cypionate	Cytochrome P450 1A1	enzyme
Estradiol cypionate	Cytochrome P450 1B1	enzyme
Estradiol cypionate	Cytochrome P450 2C19	enzyme
Estradiol cypionate	Cytochrome P450 2C8	enzyme
Estradiol cypionate	Cytochrome P450 2C9	enzyme
Estradiol cypionate	Solute carrier family 22 member 8	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol cypionate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol cypionate	Nuclear receptor coactivator 2	target
Estradiol cypionate	G-protein coupled estrogen receptor 1	target
Estradiol cypionate	ATP synthase subunit a	target
Estradiol cypionate	Beclin-1	target
Estradiol cypionate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol cypionate	Estrogen-related receptor gamma	target
Estradiol dienanthate	Estrogen receptor alpha	target
Estradiol dienanthate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol dienanthate	Sex hormone-binding globulin	carrier
Estradiol dienanthate	Estrogen receptor beta	target
Estradiol dienanthate	Cytochrome P450 1A2	enzyme
Estradiol dienanthate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol dienanthate	Serum albumin	carrier
Estradiol dienanthate	Fatty acid-binding protein, intestinal	carrier
Estradiol dienanthate	Cytochrome P450 3A4	enzyme
Estradiol dienanthate	Cytochrome P450 3A5	enzyme
Estradiol dienanthate	Cytochrome P450 3A7	enzyme
Estradiol dienanthate	Solute carrier family 22 member 2	transporter
Estradiol dienanthate	Solute carrier family 22 member 1	transporter
Estradiol dienanthate	Solute carrier family 22 member 3	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol dienanthate	Multidrug resistance-associated protein 7	transporter
Estradiol dienanthate	Solute carrier family 22 member 11	transporter
Estradiol dienanthate	ATP-binding cassette sub-family G member 2	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol dienanthate	P-glycoprotein 1	transporter
Estradiol dienanthate	Cytochrome P450 1A1	enzyme
Estradiol dienanthate	Cytochrome P450 1B1	enzyme
Estradiol dienanthate	Cytochrome P450 2C19	enzyme
Estradiol dienanthate	Cytochrome P450 2C8	enzyme
Estradiol dienanthate	Cytochrome P450 2C9	enzyme
Estradiol dienanthate	Solute carrier family 22 member 8	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol dienanthate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol dienanthate	Nuclear receptor coactivator 2	target
Estradiol dienanthate	G-protein coupled estrogen receptor 1	target
Estradiol dienanthate	ATP synthase subunit a	target
Estradiol dienanthate	Beclin-1	target
Estradiol dienanthate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol dienanthate	Estrogen-related receptor gamma	target
Estradiol valerate	Estrogen receptor alpha	target
Estradiol valerate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol valerate	Sex hormone-binding globulin	carrier
Estradiol valerate	Estrogen receptor beta	target
Estradiol valerate	Cytochrome P450 1A2	enzyme
Estradiol valerate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol valerate	Serum albumin	carrier
Estradiol valerate	Fatty acid-binding protein, intestinal	carrier
Estradiol valerate	Cytochrome P450 3A4	enzyme
Estradiol valerate	Cytochrome P450 3A5	enzyme
Estradiol valerate	Cytochrome P450 3A7	enzyme
Estradiol valerate	Solute carrier family 22 member 2	transporter
Estradiol valerate	Solute carrier family 22 member 1	transporter
Estradiol valerate	Solute carrier family 22 member 3	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol valerate	Multidrug resistance-associated protein 7	transporter
Estradiol valerate	Solute carrier family 22 member 11	transporter
Estradiol valerate	ATP-binding cassette sub-family G member 2	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol valerate	P-glycoprotein 1	transporter
Estradiol valerate	Cytochrome P450 1A1	enzyme
Estradiol valerate	Cytochrome P450 1B1	enzyme
Estradiol valerate	Cytochrome P450 2C19	enzyme
Estradiol valerate	Cytochrome P450 2C8	enzyme
Estradiol valerate	Cytochrome P450 2C9	enzyme
Estradiol valerate	Solute carrier family 22 member 8	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol valerate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol valerate	Nuclear receptor coactivator 2	target
Estradiol valerate	G-protein coupled estrogen receptor 1	target
Estradiol valerate	ATP synthase subunit a	target
Estradiol valerate	Beclin-1	target
Estradiol valerate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol valerate	Estrogen-related receptor gamma	target
Isavuconazole	Cytochrome P450 3A4	enzyme
Isavuconazole	Cytochrome P450 3A5	enzyme
Isavuconazole	Cytochrome P450 2C8	enzyme
Isavuconazole	Cytochrome P450 2C9	enzyme
Isavuconazole	Cytochrome P450 2C19	enzyme
Isavuconazole	Cytochrome P450 2D6	enzyme
Isavuconazole	Cytochrome P450 2B6	enzyme
Isavuconazole	UDP-glucuronosyltransferase 1-9	enzyme
Isavuconazole	UDP-glucuronosyltransferase 1-8	enzyme
Isavuconazole	P-glycoprotein 1	transporter
Isavuconazole	ATP-binding cassette sub-family G member 2	transporter
Isavuconazole	Solute carrier family 22 member 2	transporter
Isavuconazole	Lanosterol 14-alpha demethylase	target
Isavuconazole	Potassium voltage-gated channel subfamily H member 2	target
Isavuconazole	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Isavuconazole	G protein-activated inward rectifier potassium channel 2	target
Isavuconazole	G protein-activated inward rectifier potassium channel 3	target
Isavuconazole	ATP-sensitive inward rectifier potassium channel 11	target
Isavuconazole	Potassium voltage-gated channel subfamily A member 5	target
Isavuconazole	Potassium voltage-gated channel subfamily D member 3	target
Isavuconazole	Potassium voltage-gated channel subfamily KQT member 1	target
Isavuconazole	Sodium channel protein type 5 subunit alpha	target
Nabiximols	Cannabinoid receptor 1	target
Nabiximols	Cannabinoid receptor 2	target
Nabiximols	G-protein coupled receptor 12	target
Nabiximols	Cytochrome P450 2C9	enzyme
Nabiximols	Cytochrome P450 2C19	enzyme
Nabiximols	Cytochrome P450 2D6	enzyme
Nabiximols	Cytochrome P450 3A4	enzyme
Nabiximols	Glycine receptor subunit alpha-1	target
Nabiximols	Glycine receptor (alpha-1/beta)	target
Nabiximols	Glycine receptor subunit alpha-3	target
Nabiximols	N-arachidonyl glycine receptor	target
Nabiximols	G-protein coupled receptor 55	target
Nabiximols	5-hydroxytryptamine receptor 1A	target
Nabiximols	5-hydroxytryptamine receptor 2A	target
Nabiximols	Neuronal acetylcholine receptor subunit alpha-7	target
Nabiximols	Delta-type opioid receptor	target
Nabiximols	Mu-type opioid receptor	target
Nabiximols	Peroxisome proliferator-activated receptor gamma	target
Nabiximols	Cytochrome P450 3A5	enzyme
Nabiximols	Arachidonate 5-lipoxygenase	enzyme
Nabiximols	Arachidonate 15-lipoxygenase	enzyme
Nabiximols	Multidrug resistance-associated protein 1	transporter
Nabiximols	ATP-binding cassette sub-family G member 2	transporter
Nabiximols	Equilibrative nucleoside transporter 1	transporter
Nabiximols	Transient receptor potential cation channel subfamily V member 1	target
Nabiximols	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Nabiximols	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Nabiximols	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Nabiximols	Transient receptor potential cation channel subfamily A member 1	target
Nabiximols	Transient receptor potential cation channel subfamily M member 8	target
Nabiximols	Transient receptor potential cation channel subfamily V member 2	target
Nabiximols	Transient receptor potential cation channel subfamily V member 3	target
Nabiximols	Transient receptor potential cation channel subfamily V member 4	target
Nabiximols	Voltage-dependent anion-selective channel protein 1	target
Nabiximols	Prostaglandin G/H synthase 1	target
Nabiximols	Prostaglandin G/H synthase 2	target
Nabiximols	Acetyl-CoA acetyltransferase, mitochondrial	target
Nabiximols	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Nabiximols	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Nabiximols	Glutathione reductase, mitochondrial	target
Nabiximols	Glutathione peroxidase 1	target
Nabiximols	Indoleamine 2,3-dioxygenase 1	target
Nabiximols	Arylalkylamine N-acetyltransferase	target
Nabiximols	Cytochrome P450 1B1	target
Nabiximols	Cytochrome P450 3A5	target
Nabiximols	Cytochrome P450 2D6	target
Nabiximols	Cytochrome P450 1A2	target
Nabiximols	Cytochrome P450 1A1	target
Nabiximols	Cytochrome P450 3A7	target
Nabiximols	Quinone oxidoreductase	target
Nabiximols	Catalase	target
Nabiximols	Fatty-acid amide hydrolase 1	target
Nabiximols	Superoxide dismutase [Cu-Zn]	target
Nabiximols	N-acylethanolamine-hydrolyzing acid amidase	target
Medical Cannabis	Cannabinoid receptor 1	target
Medical Cannabis	Cannabinoid receptor 2	target
Medical Cannabis	Cytochrome P450 2C9	enzyme
Medical Cannabis	Cytochrome P450 2C19	enzyme
Medical Cannabis	Cytochrome P450 2D6	enzyme
Medical Cannabis	Cytochrome P450 3A4	enzyme
Medical Cannabis	G-protein coupled receptor 12	target
Medical Cannabis	Glycine receptor subunit alpha-1	target
Medical Cannabis	Glycine receptor (alpha-1/beta)	target
Medical Cannabis	Glycine receptor subunit alpha-3	target
Medical Cannabis	N-arachidonyl glycine receptor	target
Medical Cannabis	G-protein coupled receptor 55	target
Medical Cannabis	5-hydroxytryptamine receptor 1A	target
Medical Cannabis	5-hydroxytryptamine receptor 2A	target
Medical Cannabis	Neuronal acetylcholine receptor subunit alpha-7	target
Medical Cannabis	Delta-type opioid receptor	target
Medical Cannabis	Mu-type opioid receptor	target
Medical Cannabis	Peroxisome proliferator-activated receptor gamma	target
Medical Cannabis	Cytochrome P450 3A5	enzyme
Medical Cannabis	Cytochrome P450 3A7	enzyme
Medical Cannabis	Cytochrome P450 1A1	enzyme
Medical Cannabis	Cytochrome P450 1A2	enzyme
Medical Cannabis	Cytochrome P450 1B1	enzyme
Medical Cannabis	Arachidonate 5-lipoxygenase	enzyme
Medical Cannabis	Arachidonate 15-lipoxygenase	enzyme
Medical Cannabis	Superoxide dismutase [Cu-Zn]	enzyme
Medical Cannabis	Multidrug resistance-associated protein 1	transporter
Medical Cannabis	ATP-binding cassette sub-family G member 2	transporter
Medical Cannabis	Equilibrative nucleoside transporter 1	transporter
Medical Cannabis	Transient receptor potential cation channel subfamily V member 1	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Medical Cannabis	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Medical Cannabis	Transient receptor potential cation channel subfamily A member 1	target
Medical Cannabis	Transient receptor potential cation channel subfamily M member 8	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 2	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 3	target
Medical Cannabis	Transient receptor potential cation channel subfamily V member 4	target
Medical Cannabis	Voltage-dependent anion-selective channel protein 1	target
Medical Cannabis	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	target
Medical Cannabis	N-acylethanolamine-hydrolyzing acid amidase	target
Medical Cannabis	Arylalkylamine N-acetyltransferase	target
Medical Cannabis	Phospholipase A2	target
Medical Cannabis	Superoxide dismutase [Cu-Zn]	target
Medical Cannabis	Fatty-acid amide hydrolase 1	target
Medical Cannabis	Catalase	target
Medical Cannabis	Quinone oxidoreductase	target
Medical Cannabis	Sphingomyelin phosphodiesterase	target
Medical Cannabis	Glutathione peroxidase 1	target
Medical Cannabis	Glutathione reductase, mitochondrial	target
Medical Cannabis	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Medical Cannabis	Indoleamine 2,3-dioxygenase 1	target
Medical Cannabis	Prostaglandin G/H synthase 1	target
Medical Cannabis	Prostaglandin G/H synthase 2	target
Medical Cannabis	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Medical Cannabis	Acetyl-CoA acetyltransferase, mitochondrial	target
Avatrombopag	ATP-binding cassette sub-family G member 2	target
Avatrombopag	Cytochrome P450 2C8	enzyme
Avatrombopag	Cytochrome P450 2C9	enzyme
Avatrombopag	Thrombopoietin receptor	target
Avatrombopag	P-glycoprotein 1	transporter
Avatrombopag	Solute carrier family 22 member 8	target
Gefitinib	Epidermal growth factor receptor	target
Gefitinib	Cytochrome P450 3A4	enzyme
Gefitinib	Cytochrome P450 2D6	enzyme
Gefitinib	P-glycoprotein 1	transporter
Gefitinib	ATP-binding cassette sub-family G member 2	transporter
Gefitinib	Cytochrome P450 3A5	enzyme
Gefitinib	Cytochrome P450 1A1	enzyme
Gefitinib	Cytochrome P450 2C9	enzyme
Gefitinib	Cytochrome P450 2C19	enzyme
Gefitinib	Serum albumin	carrier
Gefitinib	Alpha-1-acid glycoprotein 1	carrier
Safinamide	Amine oxidase [flavin-containing] B	target
Safinamide	Amine oxidase [flavin-containing] A	enzyme
Safinamide	ATP-binding cassette sub-family G member 2	transporter
Safinamide	Solute carrier organic anion transporter family member 3A1	transporter
Safinamide	Cytochrome P450 3A4	enzyme
Safinamide	Cytochrome P450 1A1	enzyme
Safinamide	Cytochrome P450 1A2	enzyme
Safinamide	Cytochrome P450 2B6	enzyme
Safinamide	Cytochrome P450 2C9	enzyme
Safinamide	Cytochrome P450 2D6	enzyme
Safinamide	Cytochrome P450 2C19	enzyme
Safinamide	Cytochrome P450 2E1	enzyme
Safinamide	Cytochrome P450 3A5	enzyme
Paritaprevir	NS3/4A protein	target
Paritaprevir	Cytochrome P450 3A4	enzyme
Paritaprevir	Cytochrome P450 3A5	enzyme
Paritaprevir	ATP-binding cassette sub-family G member 2	transporter
Paritaprevir	P-glycoprotein 1	transporter
Paritaprevir	Solute carrier organic anion transporter family member 1B1	transporter
Paritaprevir	Solute carrier organic anion transporter family member 1B3	transporter
Paritaprevir	UDP-glucuronosyltransferase 1-1	enzyme
Fostamatinib	Adenosine receptor A3	target
Fostamatinib	vesicular monoamine transporter 2 (VMAT2)	target
Fostamatinib	Fatty-acid amide hydrolase 1	target
Fostamatinib	Equilibrative nucleoside transporter 1	target
Fostamatinib	UDP-glucuronosyltransferase 1-1	target
Fostamatinib	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Fostamatinib	Arachidonate 5-lipoxygenase	target
Fostamatinib	Cathepsin S	target
Fostamatinib	Cathepsin L1	target
Fostamatinib	Tyrosine-protein kinase ABL1	target
Fostamatinib	Calcium-dependent protein kinase 1	target
Fostamatinib	Serine/threonine-protein kinase PknB	target
Fostamatinib	Ribosomal protein S6 kinase alpha-6	target
Fostamatinib	Non-receptor tyrosine-protein kinase TYK2	target
Fostamatinib	Atypical kinase COQ8A, mitochondrial	target
Fostamatinib	Tyrosine-protein kinase JAK1	target
Fostamatinib	Hepatocyte growth factor receptor	target
Fostamatinib	Serine/threonine-protein kinase NIM1	target
Fostamatinib	Serine/threonine-protein kinase MST4	target
Fostamatinib	cAMP-dependent protein kinase catalytic subunit alpha	target
Fostamatinib	Serine/threonine-protein kinase 24	target
Fostamatinib	Serine/threonine-protein kinase 3	target
Fostamatinib	Tyrosine-protein kinase Tec	target
Fostamatinib	Tyrosine-protein kinase SYK	target
Fostamatinib	Serine/threonine-protein kinase 33	target
Fostamatinib	Serine/threonine-protein kinase 35	target
Fostamatinib	Serine/threonine-protein kinase 36	target
Fostamatinib	Serine/threonine-protein kinase 38	target
Fostamatinib	Serine/threonine-protein kinase 38-like	target
Fostamatinib	STE20/SPS1-related proline-alanine-rich protein kinase	target
Fostamatinib	Serine/threonine-protein kinase TAO1	target
Fostamatinib	Serine/threonine-protein kinase TAO2	target
Fostamatinib	Serine/threonine-protein kinase TAO3	target
Fostamatinib	Serine/threonine-protein kinase TBK1	target
Fostamatinib	Angiopoietin-1 receptor	target
Fostamatinib	Dual specificity testis-specific protein kinase 1	target
Fostamatinib	TGF-beta receptor type-1	target
Fostamatinib	TGF-beta receptor type-2	target
Fostamatinib	Tyrosine-protein kinase receptor Tie-1	target
Fostamatinib	Serine/threonine-protein kinase tousled-like 1	target
Fostamatinib	Serine/threonine-protein kinase tousled-like 2	target
Fostamatinib	TRAF2 and NCK-interacting protein kinase	target
Fostamatinib	Non-receptor tyrosine-protein kinase TNK1	target
Fostamatinib	Activated CDC42 kinase 1	target
Fostamatinib	Serine/threonine-protein kinase TNNI3K	target
Fostamatinib	Testis-specific serine/threonine-protein kinase 1	target
Fostamatinib	Dual specificity protein kinase TTK	target
Fostamatinib	Tyrosine-protein kinase TXK	target
Fostamatinib	Tyrosine-protein kinase receptor TYRO3	target
Fostamatinib	Serine/threonine-protein kinase ULK1	target
Fostamatinib	Serine/threonine-protein kinase ULK2	target
Fostamatinib	Serine/threonine-protein kinase ULK3	target
Fostamatinib	Wee1-like protein kinase	target
Fostamatinib	Tyrosine-protein kinase Yes	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 19	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase MLT	target
Fostamatinib	Tyrosine-protein kinase ZAP-70	target
Fostamatinib	AP2-associated protein kinase 1	target
Fostamatinib	Abelson tyrosine-protein kinase 2	target
Fostamatinib	Activin receptor type-1	target
Fostamatinib	Activin receptor type-1B	target
Fostamatinib	Atypical kinase COQ8B, mitochondrial	target
Fostamatinib	ALK tyrosine kinase receptor	target
Fostamatinib	Ankyrin repeat and protein kinase domain-containing protein 1	target
Fostamatinib	Aurora kinase A	target
Fostamatinib	Aurora kinase B	target
Fostamatinib	Aurora kinase C	target
Fostamatinib	Tyrosine-protein kinase receptor UFO	target
Fostamatinib	Tyrosine-protein kinase Blk	target
Fostamatinib	BMP-2-inducible protein kinase	target
Fostamatinib	Bone morphogenetic protein receptor type-1B	target
Fostamatinib	Bone morphogenetic protein receptor type-2	target
Fostamatinib	Cytoplasmic tyrosine-protein kinase BMX	target
Fostamatinib	Serine/threonine-protein kinase B-raf	target
Fostamatinib	Tyrosine-protein kinase BTK	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase type 1	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase type 1D	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase type 1G	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase type II subunit alpha	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase type II subunit beta	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase type II subunit delta	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase type II subunit gamma	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase kinase 1	target
Fostamatinib	Calcium/calmodulin-dependent protein kinase kinase 2	target
Fostamatinib	Peripheral plasma membrane protein CASK	target
Fostamatinib	Kappa-casein	target
Fostamatinib	Cyclin-dependent kinase 1	target
Fostamatinib	Serine/threonine-protein kinase MRCK gamma	target
Fostamatinib	Cyclin-dependent kinase 4	target
Fostamatinib	Cyclin-dependent kinase-like 1	target
Fostamatinib	Cyclin-dependent kinase-like 2	target
Fostamatinib	Serine/threonine-protein kinase Chk1	target
Fostamatinib	Serine/threonine-protein kinase Chk2	target
Fostamatinib	Citron Rho-interacting kinase	target
Fostamatinib	Dual specificity protein kinase CLK1	target
Fostamatinib	Dual specificity protein kinase CLK2	target
Fostamatinib	Dual specificity protein kinase CLK3	target
Fostamatinib	Dual specificity protein kinase CLK4	target
Fostamatinib	Macrophage colony-stimulating factor 1 receptor	target
Fostamatinib	Tyrosine-protein kinase CSK	target
Fostamatinib	Casein kinase I isoform alpha	target
Fostamatinib	Casein kinase II subunit alpha	target
Fostamatinib	Casein kinase II subunit alpha'	target
Fostamatinib	Death-associated protein kinase 1	target
Fostamatinib	Death-associated protein kinase 2	target
Fostamatinib	Death-associated protein kinase 3	target
Fostamatinib	Serine/threonine-protein kinase DCLK1	target
Fostamatinib	Serine/threonine-protein kinase DCLK2	target
Fostamatinib	Serine/threonine-protein kinase DCLK3	target
Fostamatinib	Epithelial discoidin domain-containing receptor 1	target
Fostamatinib	Discoidin domain-containing receptor 2	target
Fostamatinib	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	target
Fostamatinib	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	target
Fostamatinib	Epidermal growth factor receptor	target
Fostamatinib	Eukaryotic translation initiation factor 2-alpha kinase 1	target
Fostamatinib	Interferon-induced, double-stranded RNA-activated protein kinase	target
Fostamatinib	eIF-2-alpha kinase GCN2	target
Fostamatinib	Ephrin type-A receptor 1	target
Fostamatinib	Ephrin type-A receptor 2	target
Fostamatinib	Ephrin type-A receptor 3	target
Fostamatinib	Ephrin type-A receptor 4	target
Fostamatinib	Ephrin type-A receptor 5	target
Fostamatinib	Ephrin type-A receptor 6	target
Fostamatinib	Ephrin type-A receptor 7	target
Fostamatinib	Ephrin type-A receptor 8	target
Fostamatinib	Ephrin type-B receptor 1	target
Fostamatinib	Ephrin type-B receptor 2	target
Fostamatinib	Ephrin type-B receptor 4	target
Fostamatinib	Ephrin type-B receptor 6	target
Fostamatinib	Receptor tyrosine-protein kinase erbB-2	target
Fostamatinib	Receptor tyrosine-protein kinase erbB-4	target
Fostamatinib	Serine/threonine-protein kinase/endoribonuclease IRE1	target
Fostamatinib	Tyrosine-protein kinase Fer	target
Fostamatinib	Tyrosine-protein kinase Fes/Fps	target
Fostamatinib	Fibroblast growth factor receptor 1	target
Fostamatinib	Fibroblast growth factor receptor 2	target
Fostamatinib	Fibroblast growth factor receptor 3	target
Fostamatinib	Tyrosine-protein kinase Fgr	target
Fostamatinib	Vascular endothelial growth factor receptor 1	target
Fostamatinib	Receptor-type tyrosine-protein kinase FLT3	target
Fostamatinib	Vascular endothelial growth factor receptor 3	target
Fostamatinib	Serine/threonine-protein kinase mTOR	target
Fostamatinib	Tyrosine-protein kinase FRK	target
Fostamatinib	Tyrosine-protein kinase Fyn	target
Fostamatinib	Cyclin-G-associated kinase	target
Fostamatinib	Glycogen synthase kinase-3 alpha	target
Fostamatinib	Glycogen synthase kinase-3 beta	target
Fostamatinib	Tyrosine-protein kinase HCK	target
Fostamatinib	Homeodomain-interacting protein kinase 2	target
Fostamatinib	Homeodomain-interacting protein kinase 3	target
Fostamatinib	Serine/threonine-protein kinase ICK	target
Fostamatinib	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
Fostamatinib	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	target
Fostamatinib	Insulin receptor	target
Fostamatinib	Insulin receptor-related protein	target
Fostamatinib	Interleukin-1 receptor-associated kinase 1	target
Fostamatinib	Interleukin-1 receptor-associated kinase 3	target
Fostamatinib	Interleukin-1 receptor-associated kinase 4	target
Fostamatinib	Tyrosine-protein kinase ITK/TSK	target
Fostamatinib	Tyrosine-protein kinase JAK2	target
Fostamatinib	Tyrosine-protein kinase JAK3	target
Fostamatinib	Vascular endothelial growth factor receptor 2	target
Fostamatinib	Serine/threonine-protein kinase SIK3	target
Fostamatinib	Mast/stem cell growth factor receptor Kit	target
Fostamatinib	Serine/threonine-protein kinase LATS1	target
Fostamatinib	Tyrosine-protein kinase Lck	target
Fostamatinib	LIM domain kinase 1	target
Fostamatinib	LIM domain kinase 2	target
Fostamatinib	Leucine-rich repeat serine/threonine-protein kinase 2	target
Fostamatinib	Leukocyte tyrosine kinase receptor	target
Fostamatinib	Tyrosine-protein kinase Lyn	target
Fostamatinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Fostamatinib	Dual specificity mitogen-activated protein kinase kinase 3	target
Fostamatinib	Dual specificity mitogen-activated protein kinase kinase 5	target
Fostamatinib	Dual specificity mitogen-activated protein kinase kinase 6	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 1	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 10	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 11	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 12	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 13	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 15	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 2	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 3	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 4	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 6	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase 9	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase kinase 1	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase kinase 2	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase kinase 3	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase kinase 4	target
Fostamatinib	Mitogen-activated protein kinase kinase kinase kinase 5	target
Fostamatinib	Mitogen-activated protein kinase 10	target
Fostamatinib	Mitogen-activated protein kinase 13	target
Fostamatinib	Mitogen-activated protein kinase 14	target
Fostamatinib	Mitogen-activated protein kinase 15	target
Fostamatinib	Mitogen-activated protein kinase 4	target
Fostamatinib	Mitogen-activated protein kinase 7	target
Fostamatinib	Mitogen-activated protein kinase 9	target
Fostamatinib	MAP kinase-activated protein kinase 5	target
Fostamatinib	Serine/threonine-protein kinase MARK1	target
Fostamatinib	Serine/threonine-protein kinase MARK2	target
Fostamatinib	MAP/microtubule affinity-regulating kinase 3	target
Fostamatinib	MAP/microtubule affinity-regulating kinase 4	target
Fostamatinib	CLIP-associating protein 1	target
Fostamatinib	Microtubule-associated serine/threonine-protein kinase 1	target
Fostamatinib	Megakaryocyte-associated tyrosine-protein kinase	target
Fostamatinib	Maternal embryonic leucine zipper kinase	target
Fostamatinib	Tyrosine-protein kinase Mer	target
Fostamatinib	Misshapen-like kinase 1	target
Fostamatinib	MAP kinase-interacting serine/threonine-protein kinase 1	target
Fostamatinib	MAP kinase-interacting serine/threonine-protein kinase 2	target
Fostamatinib	Macrophage-stimulating protein receptor	target
Fostamatinib	Muscle, skeletal receptor tyrosine-protein kinase	target
Fostamatinib	Myosin light chain kinase, smooth muscle	target
Fostamatinib	Myosin light chain kinase 2, skeletal/cardiac muscle	target
Fostamatinib	Myosin light chain kinase 3	target
Fostamatinib	Myosin light chain kinase family member 4	target
Fostamatinib	Myosin-IIIa	target
Fostamatinib	Serine/threonine-protein kinase Nek1	target
Fostamatinib	Serine/threonine-protein kinase Nek11	target
Fostamatinib	Serine/threonine-protein kinase Nek2	target
Fostamatinib	Serine/threonine-protein kinase Nek3	target
Fostamatinib	Serine/threonine-protein kinase Nek4	target
Fostamatinib	Serine/threonine-protein kinase Nek5	target
Fostamatinib	Serine/threonine-protein kinase Nek9	target
Fostamatinib	High affinity nerve growth factor receptor	target
Fostamatinib	BDNF/NT-3 growth factors receptor	target
Fostamatinib	NT-3 growth factor receptor	target
Fostamatinib	NUAK family SNF1-like kinase 1	target
Fostamatinib	NUAK family SNF1-like kinase 2	target
Fostamatinib	Serine/threonine-protein kinase OSR1	target
Fostamatinib	Serine/threonine-protein kinase PAK 1	target
Fostamatinib	Serine/threonine-protein kinase PAK 2	target
Fostamatinib	Serine/threonine-protein kinase PAK 3	target
Fostamatinib	Serine/threonine-protein kinase PAK 4	target
Fostamatinib	Serine/threonine-protein kinase PAK 6	target
Fostamatinib	Serine/threonine-protein kinase PAK 5	target
Fostamatinib	Cyclin-dependent kinase 16	target
Fostamatinib	Cyclin-dependent kinase 17	target
Fostamatinib	Platelet-derived growth factor receptor alpha	target
Fostamatinib	Platelet-derived growth factor receptor beta	target
Fostamatinib	3-phosphoinositide-dependent protein kinase 1	target
Fostamatinib	Cyclin-dependent kinase 15	target
Fostamatinib	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	target
Fostamatinib	Phosphatidylinositol 4-kinase beta	target
Fostamatinib	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	target
Fostamatinib	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	target
Fostamatinib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Fostamatinib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	target
Fostamatinib	Serine/threonine-protein kinase pim-1	target
Fostamatinib	Serine/threonine-protein kinase pim-3	target
Fostamatinib	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	target
Fostamatinib	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	target
Fostamatinib	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	target
Fostamatinib	Serine/threonine-protein kinase N1	target
Fostamatinib	Serine/threonine-protein kinase N2	target
Fostamatinib	Serine/threonine-protein kinase PLK1	target
Fostamatinib	Serine/threonine-protein kinase PLK2	target
Fostamatinib	Serine/threonine-protein kinase PLK3	target
Fostamatinib	Serine/threonine-protein kinase PLK4	target
Fostamatinib	5'-AMP-activated protein kinase catalytic subunit alpha-1	target
Fostamatinib	5'-AMP-activated protein kinase	target
Fostamatinib	cAMP-dependent protein kinase catalytic subunit beta	target
Fostamatinib	Protein kinase C delta type	target
Fostamatinib	Protein kinase C epsilon type	target
Fostamatinib	Protein kinase C gamma type (PRKCG)	target
Fostamatinib	Protein kinase C iota type	target
Fostamatinib	Protein kinase C theta type	target
Fostamatinib	Serine/threonine-protein kinase D1	target
Fostamatinib	cGMP-dependent protein kinase 2	target
Fostamatinib	Serine/threonine-protein kinase PRP4 homolog	target
Fostamatinib	Focal adhesion kinase 1	target
Fostamatinib	Protein-tyrosine kinase 2-beta	target
Fostamatinib	Protein-tyrosine kinase 6	target
Fostamatinib	RAF proto-oncogene serine/threonine-protein kinase	target
Fostamatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Fostamatinib	Serine/threonine-protein kinase RIO1	target
Fostamatinib	Serine/threonine-protein kinase RIO2	target
Fostamatinib	Serine/threonine-protein kinase RIO3	target
Fostamatinib	Receptor-interacting serine/threonine-protein kinase 1	target
Fostamatinib	Receptor-interacting serine/threonine-protein kinase 2	target
Fostamatinib	Receptor-interacting serine/threonine-protein kinase 4	target
Fostamatinib	Rho-associated protein kinase 2	target
Fostamatinib	Proto-oncogene tyrosine-protein kinase ROS	target
Fostamatinib	Ribosomal protein S6 kinase alpha-1	target
Fostamatinib	Ribosomal protein S6 kinase alpha-3	target
Fostamatinib	Serine/threonine-protein kinase SBK1	target
Fostamatinib	Uncharacterized serine/threonine-protein kinase SBK3	target
Fostamatinib	Serine/threonine-protein kinase Sgk3	target
Fostamatinib	Serine/threonine-protein kinase SIK1	target
Fostamatinib	Serine/threonine-protein kinase SIK2	target
Fostamatinib	STE20-like serine/threonine-protein kinase	target
Fostamatinib	SNF-related serine/threonine-protein kinase	target
Fostamatinib	Proto-oncogene tyrosine-protein kinase Src	target
Fostamatinib	Tyrosine-protein kinase Srms	target
Fostamatinib	Serine/threonine-protein kinase 10	target
Fostamatinib	Serine/threonine-protein kinase 16	target
Fostamatinib	Serine/threonine-protein kinase 17A	target
Fostamatinib	Serine/threonine-protein kinase 17B	target
Fostamatinib	Serine/threonine-protein kinase 32A	target
Fostamatinib	Cytochrome P450 3A4	enzyme
Fostamatinib	ATP-binding cassette sub-family G member 2	transporter
Fostamatinib	ATP-binding cassette sub-family B member 5	transporter
Fostamatinib	UDP-glucuronosyltransferase 1-9	enzyme
Lansoprazole	Potassium-transporting ATPase alpha chain 1	target
Lansoprazole	Cytochrome P450 2C19	enzyme
Lansoprazole	Cytochrome P450 2C9	enzyme
Lansoprazole	Cytochrome P450 3A4	enzyme
Lansoprazole	P-glycoprotein 1	transporter
Lansoprazole	ATP-binding cassette sub-family G member 2	transporter
Lansoprazole	Cytochrome P450 1A1	enzyme
Lansoprazole	Cytochrome P450 1B1	enzyme
Lansoprazole	Cytochrome P450 2C18	enzyme
Lansoprazole	Cytochrome P450 2C8	enzyme
Lansoprazole	Cytochrome P450 2D6	enzyme
Lansoprazole	Microtubule-associated protein tau	target
Lansoprazole	Solute carrier family 22 member 8	transporter
Lansoprazole	Solute carrier family 22 member 1	transporter
Lansoprazole	Solute carrier family 22 member 2	transporter
Lansoprazole	Solute carrier family 22 member 3	transporter
Pravastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Pravastatin	Solute carrier organic anion transporter family member 2B1	transporter
Pravastatin	P-glycoprotein 1	transporter
Pravastatin	Solute carrier organic anion transporter family member 1A2	transporter
Pravastatin	Solute carrier family 22 member 6	transporter
Pravastatin	Solute carrier family 22 member 8	transporter
Pravastatin	Canalicular multispecific organic anion transporter 1	transporter
Pravastatin	Solute carrier family 22 member 11	transporter
Pravastatin	ATP-binding cassette sub-family G member 2	transporter
Pravastatin	Solute carrier family 22 member 7	transporter
Pravastatin	Solute carrier organic anion transporter family member 1B1	transporter
Pravastatin	Monocarboxylate transporter 1	transporter
Pravastatin	Bile salt export pump	transporter
Pravastatin	Solute carrier organic anion transporter family member 1B3	transporter
Pravastatin	Histone deacetylase 2	target
Dovitinib	Cytochrome P450 1A1	enzyme
Dovitinib	Cytochrome P450 1A2	enzyme
Dovitinib	Canalicular multispecific organic anion transporter 2	transporter
Dovitinib	ATP-binding cassette sub-family G member 2	transporter
Dovitinib	UDP-glucuronosyltransferase 1-3	enzyme
Dovitinib	UDP-glucuronosyltransferase 2B7	enzyme
Dovitinib	Nuclear receptor subfamily 1 group I member 2	target
Dovitinib	Solute carrier organic anion transporter family member 1B1	transporter
Dovitinib	Solute carrier organic anion transporter family member 2B1	transporter
Dovitinib	Cytochrome P450 2C19	enzyme
Dovitinib	Cytochrome P450 3A4	enzyme
Dovitinib	Solute carrier organic anion transporter family member 1B3	transporter
Dovitinib	P-glycoprotein 1	transporter
Eltrombopag	Thrombopoietin receptor	target
Eltrombopag	Cytochrome P450 2C8	enzyme
Eltrombopag	Cytochrome P450 1A2	enzyme
Eltrombopag	UDP-glucuronosyltransferase 1-1	enzyme
Eltrombopag	UDP-glucuronosyltransferase 1-3	enzyme
Eltrombopag	Solute carrier organic anion transporter family member 1B1	transporter
Eltrombopag	ATP-binding cassette sub-family G member 2	transporter
Eltrombopag	UDP-glucuronosyltransferase 1-9	enzyme
Teriflunomide	ATP-binding cassette sub-family G member 2	transporter
Teriflunomide	Dihydroorotate dehydrogenase (quinone), mitochondrial	target
Teriflunomide	Cytochrome P450 2C8	enzyme
Teriflunomide	Solute carrier organic anion transporter family member 1B1	transporter
Teriflunomide	Cytochrome P450 1A2	enzyme
Vemurafenib	Serum albumin	carrier
Vemurafenib	Alpha-1-acid glycoprotein 1	carrier
Vemurafenib	Cytochrome P450 1A2	enzyme
Vemurafenib	Cytochrome P450 2D6	enzyme
Vemurafenib	Cytochrome P450 3A4	enzyme
Vemurafenib	Serine/threonine-protein kinase B-raf	target
Vemurafenib	Multidrug resistance-associated protein 1	transporter
Vemurafenib	ATP-binding cassette sub-family G member 2	transporter
Vemurafenib	Cytochrome P450 2C9	enzyme
Vemurafenib	Cytochrome P450 2C8	enzyme
Vemurafenib	Cytochrome P450 2B6	enzyme
Vemurafenib	P-glycoprotein 1	transporter
Progesterone	Progesterone receptor	target
Progesterone	Estrogen receptor alpha	target
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Progesterone	Cytochrome P450 2C19	enzyme
Progesterone	Cytochrome P450 2C9	enzyme
Progesterone	Cytochrome P450 3A4	enzyme
Progesterone	Cytochrome P450 3A5	enzyme
Progesterone	Cytochrome P450 3A7	enzyme
Progesterone	P-glycoprotein 1	transporter
Progesterone	Solute carrier family 22 member 2	transporter
Progesterone	Solute carrier family 22 member 1	transporter
Progesterone	Solute carrier family 22 member 3	transporter
Progesterone	Bile salt export pump	transporter
Progesterone	Multidrug resistance-associated protein 1	transporter
Progesterone	Sodium/bile acid cotransporter	transporter
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Progesterone	Cytochrome P450 1A1	enzyme
Progesterone	Cytochrome P450 1B1	enzyme
Progesterone	Cytochrome P450 2A6	enzyme
Progesterone	Cytochrome P450 2D6	enzyme
Progesterone	Mineralocorticoid receptor	target
Progesterone	Kappa-type opioid receptor	target
Progesterone	Alpha-1-acid glycoprotein 1	target
Progesterone	Glucocorticoid receptor	target
Progesterone	Androgen receptor	target
Progesterone	Sex hormone-binding globulin	target
Progesterone	Solute carrier organic anion transporter family member 1B1	transporter
Progesterone	ATP-binding cassette sub-family G member 2	transporter
Progesterone	Estrogen receptor beta	target
Progesterone	Solute carrier organic anion transporter family member 1B3	transporter
Fusidic acid	Chloramphenicol acetyltransferase 3	target
Fusidic acid	Chloramphenicol acetyltransferase	target
Fusidic acid	Bile salt export pump	transporter
Fusidic acid	Canalicular multispecific organic anion transporter 1	transporter
Fusidic acid	Elongation factor G	target
Fusidic acid	Cytochrome P450 2D6	enzyme
Fusidic acid	Cytochrome P450 3A4	enzyme
Fusidic acid	UDP-glucuronosyltransferase 1-1	enzyme
Fusidic acid	ATP-binding cassette sub-family G member 2	transporter
Fusidic acid	Solute carrier organic anion transporter family member 1B1	transporter
Dacomitinib	Cytochrome P450 2D6	enzyme
Dacomitinib	Serum albumin	carrier
Dacomitinib	Cytochrome P450 3A4	enzyme
Dacomitinib	Cytochrome P450 2C9	enzyme
Dacomitinib	UDP-glucuronosyltransferase 1-1	enzyme
Dacomitinib	P-glycoprotein 1	transporter
Dacomitinib	ATP-binding cassette sub-family G member 2	transporter
Dacomitinib	Solute carrier family 22 member 1	transporter
Dacomitinib	Epidermal growth factor receptor	target
Venetoclax	Apoptosis regulator Bcl-2	target
Venetoclax	Cytochrome P450 3A4	enzyme
Venetoclax	P-glycoprotein 1	transporter
Venetoclax	ATP-binding cassette sub-family G member 2	transporter
Venetoclax	Solute carrier organic anion transporter family member 1B1	transporter
Gilteritinib	Serum albumin	carrier
Gilteritinib	Cytochrome P450 3A4	enzyme
Gilteritinib	Receptor-type tyrosine-protein kinase FLT3	target
Gilteritinib	Serotonin Receptors	target
Gilteritinib	P-glycoprotein 1	transporter
Gilteritinib	Multidrug and toxin extrusion protein 1	transporter
Gilteritinib	ATP-binding cassette sub-family G member 2	transporter
Gilteritinib	Solute carrier family 22 member 1	transporter
Gilteritinib	Tyrosine-protein kinase receptor UFO	target
Gilteritinib	ALK tyrosine kinase receptor	target
Glasdegib	Cytochrome P450 3A4	enzyme
Glasdegib	Smoothened homolog	target
Glasdegib	Cytochrome P450 2C8	enzyme
Glasdegib	UDP-glucuronosyltransferase 1-9	enzyme
Glasdegib	Serum albumin	carrier
Glasdegib	P-glycoprotein 1	transporter
Glasdegib	ATP-binding cassette sub-family G member 2	transporter
Glasdegib	Multidrug and toxin extrusion protein 1	transporter
Glasdegib	Multidrug and toxin extrusion protein 2	transporter
Olaparib	Poly [ADP-ribose] polymerase 1	target
Olaparib	Cytochrome P450 3A4	enzyme
Olaparib	Cytochrome P450 2B6	enzyme
Olaparib	Poly [ADP-ribose] polymerase 2	target
Olaparib	Poly [ADP-ribose] polymerase 3	target
Olaparib	Cytochrome P450 3A5	enzyme
Olaparib	P-glycoprotein 1	transporter
Olaparib	ATP-binding cassette sub-family G member 2	transporter
Palbociclib	Cyclin-dependent kinase 4	target
Palbociclib	Cyclin-dependent kinase 6	target
Palbociclib	Cytochrome P450 3A4	enzyme
Palbociclib	Bile salt sulfotransferase	enzyme
Palbociclib	P-glycoprotein 1	transporter
Palbociclib	ATP-binding cassette sub-family G member 2	transporter
Palbociclib	Serum albumin	carrier
Palbociclib	Solute carrier family 22 member 1	transporter
Beclomethasone dipropionate	Corticosteroid-binding globulin	carrier
Beclomethasone dipropionate	Glucocorticoid receptor	target
Beclomethasone dipropionate	Cytochrome P450 3A5	enzyme
Beclomethasone dipropionate	Cytochrome P450 3A4	enzyme
Beclomethasone dipropionate	P-glycoprotein 1	transporter
Beclomethasone dipropionate	ATP-binding cassette sub-family G member 2	transporter
Beclomethasone dipropionate	Solute carrier organic anion transporter family member 1B1	transporter
Beclomethasone dipropionate	Solute carrier organic anion transporter family member 1B3	transporter
Fedratinib	P-glycoprotein 1	transporter
Fedratinib	ATP-binding cassette sub-family G member 2	transporter
Fedratinib	Solute carrier organic anion transporter family member 1B1	transporter
Fedratinib	Solute carrier organic anion transporter family member 1B3	transporter
Fedratinib	POU domain, class 2, transcription factor 2	transporter
Fedratinib	Multidrug and toxin extrusion protein 1	transporter
Fedratinib	Multidrug and toxin extrusion protein 2	transporter
Fedratinib	Cytochrome P450 3A4	enzyme
Fedratinib	Cytochrome P450 2C19	enzyme
Fedratinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Fedratinib	Tyrosine-protein kinase JAK2	target
Fedratinib	Receptor-type tyrosine-protein kinase FLT3	target
Fedratinib	Tyrosine-protein kinase JAK1	target
Fedratinib	Cytochrome P450 2D6	enzyme
Istradefylline	Cytochrome P450 1A1	enzyme
Istradefylline	Cytochrome P450 3A4	enzyme
Istradefylline	Cytochrome P450 3A5	enzyme
Istradefylline	Cytochrome P450 1A2	enzyme
Istradefylline	Cytochrome P450 2B6	enzyme
Istradefylline	Cytochrome P450 2C8	enzyme
Istradefylline	Cytochrome P450 2C9	enzyme
Istradefylline	Cytochrome P450 2C18	enzyme
Istradefylline	Cytochrome P450 2D6	enzyme
Istradefylline	Cytochrome P450 3A Subfamily	enzyme
Istradefylline	P-glycoprotein 1	transporter
Istradefylline	Adenosine receptor A2a	target
Istradefylline	Adenosine receptor A1	target
Istradefylline	Serum albumin	carrier
Istradefylline	alpha1-acid glycoprotein	carrier
Istradefylline	ATP-binding cassette sub-family G member 2	transporter
Istradefylline	Solute carrier organic anion transporter family member 1B1	transporter
Istradefylline	Solute carrier organic anion transporter family member 1B3	transporter
Istradefylline	Solute carrier family 22 member 6	transporter
Istradefylline	POU domain, class 2, transcription factor 2	transporter
Istradefylline	Multidrug and toxin extrusion protein 1	transporter
Istradefylline	Multidrug and toxin extrusion protein 2	transporter
Caffeine	Adenosine receptor A1	target
Caffeine	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Caffeine	Adenosine receptor A2a	target
Caffeine	Cytochrome P450 1A2	enzyme
Caffeine	Ryanodine receptor 1	target
Caffeine	Cytochrome P450 3A4	enzyme
Caffeine	Cytochrome P450 2E1	enzyme
Caffeine	Cytochrome P450 2C8	enzyme
Caffeine	Cytochrome P450 2C9	enzyme
Caffeine	Cytochrome P450 1A1	enzyme
Caffeine	Cytochrome P450 1B1	enzyme
Caffeine	Cytochrome P450 2D6	enzyme
Caffeine	Cyclic nucleotide phosphodiesterase	target
Caffeine	DNA-dependent protein kinase catalytic subunit	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	target
Caffeine	Inositol 1,4,5-trisphosphate receptor	target
Caffeine	Serine-protein kinase ATM	target
Caffeine	ATP-binding cassette sub-family G member 2	transporter
Caffeine	Adenosine receptor A2b	target
Caffeine	Adenosine receptor A3	target
Caffeine	Phosphodiesterase enzymes	target
Lasmiditan	5-hydroxytryptamine receptor 1F	target
Lasmiditan	P-glycoprotein 1	transporter
Lasmiditan	ATP-binding cassette sub-family G member 2	transporter
Lasmiditan	Solute carrier family 22 member 1	transporter
Lasmiditan	Multidrug and toxin extrusion protein 1	transporter
Lasmiditan	Multidrug and toxin extrusion protein 2	transporter
Lasmiditan	Cytochrome P450 2D6	enzyme
Darolutamide	Cytochrome P450 3A4	enzyme
Darolutamide	UDP-glucuronosyltransferase 1-9	enzyme
Darolutamide	Androgen receptor	target
Darolutamide	ATP-binding cassette sub-family G member 2	transporter
Darolutamide	P-glycoprotein 1	transporter
Darolutamide	Serum albumin	carrier
Darolutamide	Progesterone receptor	target
Darolutamide	Solute carrier organic anion transporter family member 1B1	transporter
Darolutamide	Solute carrier organic anion transporter family member 1B3	transporter
Upadacitinib	Tyrosine-protein kinase JAK1	target
Upadacitinib	Cytochrome P450 3A4	enzyme
Upadacitinib	Cytochrome P450 2D6	enzyme
Upadacitinib	P-glycoprotein 1	transporter
Upadacitinib	ATP-binding cassette sub-family G member 2	transporter
Upadacitinib	Solute carrier organic anion transporter family member 1B1	transporter
Tafamidis	Transthyretin	target
Tafamidis	Solute carrier family 22 member 6	transporter
Tafamidis	Solute carrier family 22 member 8	transporter
Tafamidis	ATP-binding cassette sub-family G member 2	transporter
Capmatinib	Cytochrome P450 3A4	enzyme
Capmatinib	Aldehyde oxidase	enzyme
Capmatinib	Hepatocyte growth factor receptor	target
Capmatinib	P-glycoprotein 1	transporter
Capmatinib	Multidrug and toxin extrusion protein 1	transporter
Capmatinib	Multidrug and toxin extrusion protein 2	transporter
Capmatinib	Cytochrome P450 1A2	enzyme
Capmatinib	ATP-binding cassette sub-family G member 2	transporter
Selpercatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Selpercatinib	Vascular endothelial growth factor receptor 1	target
Selpercatinib	Vascular endothelial growth factor receptor 3	target
Selpercatinib	Fibroblast growth factor receptor 1	target
Selpercatinib	Fibroblast growth factor receptor 2	target
Selpercatinib	Fibroblast growth factor receptor 3	target
Selpercatinib	Cytochrome P450 3A4	enzyme
Selpercatinib	Cytochrome P450 2C8	enzyme
Selpercatinib	Cytochrome P450 3A Subfamily	enzyme
Selpercatinib	P-glycoprotein 1	transporter
Selpercatinib	ATP-binding cassette sub-family G member 2	transporter
Selpercatinib	Multidrug and toxin extrusion protein 1	transporter
Ripretinib	Mast/stem cell growth factor receptor Kit	target
Ripretinib	Platelet-derived growth factor receptor beta	target
Ripretinib	Angiopoietin-1 receptor	target
Ripretinib	Vascular endothelial growth factor receptor 2	target
Ripretinib	Serine/threonine-protein kinase B-raf	target
Ripretinib	Platelet-derived growth factor receptor alpha	target
Ripretinib	Cytochrome P450 2C8	enzyme
Ripretinib	Mast/stem cell growth factor receptor Kit	enzyme
Ripretinib	Platelet-derived growth factor receptor alpha	enzyme
Ripretinib	Serum albumin	carrier
Ripretinib	alpha1-acid glycoprotein	carrier
Ripretinib	P-glycoprotein 1	transporter
Ripretinib	ATP-binding cassette sub-family G member 2	transporter
Ripretinib	Multidrug and toxin extrusion protein 1	transporter
Ripretinib	Cytochrome P450 3A4	enzyme
Ripretinib	Cytochrome P450 2D6	enzyme
Ripretinib	Cytochrome P450 2E1	enzyme
Clofazimine	Cytochrome P450 3A4	enzyme
Clofazimine	Peroxisome proliferator-activated receptor gamma	target
Clofazimine	Cytochrome P450 2C8	enzyme
Clofazimine	Cytochrome P450 2D6	enzyme
Clofazimine	Cytochrome P450 3A5	enzyme
Clofazimine	Potassium voltage-gated channel subfamily A member 3	target
Clofazimine	Serum albumin	carrier
Clofazimine	P-glycoprotein 1	transporter
Clofazimine	ATP-binding cassette sub-family G member 2	transporter
Clofazimine	Multidrug resistance-associated protein 1	transporter
Dexamethasone acetate	Glucocorticoid receptor	target
Dexamethasone acetate	Annexin A1	target
Dexamethasone acetate	Nitric oxide synthase, inducible	target
Dexamethasone acetate	Nuclear receptor subfamily 0 group B member 1	target
Dexamethasone acetate	Cytochrome P450 3A4	enzyme
Dexamethasone acetate	Cytochrome P450 3A5	enzyme
Dexamethasone acetate	Cytochrome P450 3A7	enzyme
Dexamethasone acetate	Bile salt export pump	transporter
Dexamethasone acetate	P-glycoprotein 1	transporter
Dexamethasone acetate	Canalicular multispecific organic anion transporter 1	transporter
Dexamethasone acetate	Solute carrier organic anion transporter family member 1A2	transporter
Dexamethasone acetate	ATP-binding cassette sub-family G member 2	transporter
Dexamethasone acetate	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Dexamethasone acetate	Cytochrome P450 1A1	enzyme
Dexamethasone acetate	Cytochrome P450 2A6	enzyme
Dexamethasone acetate	Cytochrome P450 2B6	enzyme
Dexamethasone acetate	Cytochrome P450 2C19	enzyme
Dexamethasone acetate	Cytochrome P450 2C8	enzyme
Dexamethasone acetate	Cytochrome P450 2E1	enzyme
Dexamethasone acetate	Cytochrome P450 3A43	enzyme
Dexamethasone acetate	Cytochrome P450 4A11	enzyme
Dexamethasone acetate	Nuclear receptor subfamily 1 group I member 2	target
Dexamethasone acetate	Cytochrome P450 11B1, mitochondrial	enzyme
Dexamethasone acetate	Serum albumin	carrier
Dexamethasone acetate	Corticosteroid 11-beta-dehydrogenase isozyme 2	enzyme
Dexamethasone acetate	Corticosteroid 11-beta-dehydrogenase isozyme 1	enzyme
Dexamethasone acetate	Solute carrier family 22 member 8	transporter
Fostemsavir	Cytochrome P450 3A4	enzyme
Fostemsavir	UDP-glucuronosyltransferases (UGTs)	enzyme
Fostemsavir	P-glycoprotein 1	transporter
Fostemsavir	ATP-binding cassette sub-family G member 2	transporter
Fostemsavir	Solute carrier organic anion transporter family member 1B1	transporter
Fostemsavir	Solute carrier organic anion transporter family member 1B3	transporter
Fostemsavir	Serum albumin	carrier
Fostemsavir	Envelope glycoprotein gp160	target
Pralsetinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Pralsetinib	Epithelial discoidin domain-containing receptor 1	target
Pralsetinib	NT-3 growth factor receptor	target
Pralsetinib	Receptor-type tyrosine-protein kinase FLT3	target
Pralsetinib	Tyrosine-protein kinase JAK1	target
Pralsetinib	Tyrosine-protein kinase JAK2	target
Pralsetinib	High affinity nerve growth factor receptor	target
Pralsetinib	Vascular endothelial growth factor receptor 2	target
Pralsetinib	Platelet-derived growth factor receptor beta	target
Pralsetinib	Fibroblast growth factor receptor 1	target
Pralsetinib	Fibroblast growth factor receptor 2	target
Pralsetinib	Cytochrome P450 3A4	enzyme
Pralsetinib	Cytochrome P450 3A5	enzyme
Pralsetinib	Cytochrome P450 2D6	enzyme
Pralsetinib	Cytochrome P450 1A2	enzyme
Pralsetinib	Cytochrome P450 2C8	enzyme
Pralsetinib	Cytochrome P450 2C9	enzyme
Pralsetinib	P-glycoprotein 1	transporter
Pralsetinib	ATP-binding cassette sub-family G member 2	transporter
Pralsetinib	Solute carrier organic anion transporter family member 1B1	transporter
Pralsetinib	Solute carrier organic anion transporter family member 1B3	transporter
Pralsetinib	Solute carrier family 22 member 6	transporter
Pralsetinib	Multidrug and toxin extrusion protein 1	transporter
Pralsetinib	Multidrug and toxin extrusion protein 2	transporter
Pralsetinib	Bile salt export pump	transporter
Lonafarnib	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	target
Lonafarnib	P-glycoprotein 1	transporter
Lonafarnib	Protein farnesyltransferase subunit beta	target
Lonafarnib	Cytochrome P450 3A Subfamily	enzyme
Lonafarnib	Cytochrome P450 2C8	enzyme
Lonafarnib	Cytochrome P450 2C19	enzyme
Lonafarnib	Cytochrome P450 1A2	enzyme
Lonafarnib	Cytochrome P450 2A6	enzyme
Lonafarnib	Cytochrome P450 2C9	enzyme
Lonafarnib	Cytochrome P450 2E1	enzyme
Lonafarnib	Solute carrier organic anion transporter family member 1B1	transporter
Lonafarnib	Solute carrier organic anion transporter family member 1B3	transporter
Lonafarnib	ATP-binding cassette sub-family G member 2	transporter
Lonafarnib	Cytochrome P450 3A4	enzyme
Lonafarnib	Cytochrome P450 3A5	enzyme
Lonafarnib	Canalicular multispecific organic anion transporter 1	transporter
Relugolix	Serum albumin	carrier
Relugolix	Alpha-1-acid glycoprotein 1	carrier
Relugolix	P-glycoprotein 1	transporter
Relugolix	ATP-binding cassette sub-family G member 2	transporter
Relugolix	Cytochrome P450 3A Subfamily	enzyme
Relugolix	Cytochrome P450 2C8	enzyme
Relugolix	Cytochrome P450 2B6	enzyme
Relugolix	Gonadotropin-releasing hormone receptor	target