Cytochrome P-450 CYP2C8 Inducers (strength unknown)

Name
Cytochrome P-450 CYP2C8 Inducers (strength unknown)
Accession Number
DBCAT004480
Description
Not Available
Drugs
DrugDrug Description
GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
RifapentineAn antibiotic agent used in the treatment of pulmonary tuberculosis.
NilotinibA kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
LumacaftorA protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
IsavuconazoleIndicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
Hydrocortisone aceponateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
Hydrocortisone butyrateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydrocortisone cypionateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone phosphateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone probutateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydrocortisone valerateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
IvosidenibAn isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation.
Hydrocortisone succinateA corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
RifamycinAn antibacterial used to treat traveler's diarrhea.
GriseofulvinAn antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
RifaximinA rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
CenobamateA small molecule drug indicated to treat partial onset seizures in adults.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Prednisolone phosphateA corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
PralsetinibA RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
Drugs & Drug Targets
DrugTargetType
GemfibrozilPeroxisome proliferator-activated receptor alphatarget
GemfibrozilCytochrome P450 2C9enzyme
GemfibrozilCytochrome P450 2C8enzyme
GemfibrozilCytochrome P450 1A2enzyme
GemfibrozilCytochrome P450 2C19enzyme
GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
GemfibrozilCytochrome P450 3A4enzyme
GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
GemfibrozilSolute carrier organic anion transporter family member 1B1target
GemfibrozilUDP-glucuronosyltransferase 2B7enzyme
GemfibrozilUDP-glucuronosyltransferase 1-9enzyme
GemfibrozilUDP-glucuronosyltransferase 2B4enzyme
GemfibrozilUDP-glucuronosyltransferase 2B17enzyme
GemfibrozilSerum albumincarrier
GemfibrozilSolute carrier family 22 member 8target
GemfibrozilSolute carrier organic anion transporter family member 2B1target
GemfibrozilSolute carrier organic anion transporter family member 1B3target
IfosfamideCytochrome P450 2B6enzyme
IfosfamideDNAtarget
IfosfamideCytochrome P450 3A4enzyme
IfosfamideCytochrome P450 3A5enzyme
IfosfamideCytochrome P450 2C9enzyme
IfosfamideCytochrome P450 2C8enzyme
IfosfamideCytochrome P450 2A6enzyme
IfosfamideCytochrome P450 2C19enzyme
IfosfamideCytochrome P450 2C18enzyme
IfosfamideProstaglandin G/H synthase 1enzyme
IfosfamideNuclear receptor subfamily 1 group I member 2target
RifapentineDNA-directed RNA polymerase subunit beta'target
RifapentineCytochrome P450 2C8enzyme
RifapentineCytochrome P450 2C9enzyme
RifapentineCytochrome P450 3A4enzyme
RifapentineCytochrome P450 2C19enzyme
RifapentineCytochrome P450 2B6enzyme
RifapentineCytochrome P450 3A Subfamilyenzyme
NilotinibTyrosine-protein kinase ABL1target
NilotinibMast/stem cell growth factor receptor Kittarget
NilotinibCytochrome P450 2D6enzyme
NilotinibCytochrome P450 2C8enzyme
NilotinibCytochrome P450 2C9enzyme
NilotinibCytochrome P450 3A4enzyme
NilotinibP-glycoprotein 1transporter
NilotinibATP-binding cassette sub-family G member 2transporter
NilotinibUDP-glucuronosyltransferase 1-1transporter
NilotinibCytochrome P450 2B6enzyme
NilotinibSolute carrier organic anion transporter family member 1B1transporter
CyclophosphamideDNAtarget
CyclophosphamideCytochrome P450 2B6enzyme
CyclophosphamideCytochrome P450 2C9enzyme
CyclophosphamideCytochrome P450 3A4enzyme
CyclophosphamideCytochrome P450 2C19enzyme
CyclophosphamideCytochrome P450 2A6enzyme
CyclophosphamideCytochrome P450 2C18enzyme
CyclophosphamideCytochrome P450 2C8enzyme
CyclophosphamideCytochrome P450 3A5enzyme
CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
ProbenecidSolute carrier family 22 member 8target
ProbenecidSolute carrier family 22 member 11target
ProbenecidSerum albumincarrier
ProbenecidSolute carrier family 22 member 2transporter
ProbenecidSolute carrier family 22 member 1transporter
ProbenecidCanalicular multispecific organic anion transporter 2transporter
ProbenecidMultidrug resistance-associated protein 4transporter
ProbenecidMultidrug resistance-associated protein 5transporter
ProbenecidMonocarboxylate transporter 2transporter
ProbenecidSolute carrier family 22 member 5transporter
ProbenecidMultidrug resistance-associated protein 6transporter
ProbenecidMultidrug resistance-associated protein 1transporter
ProbenecidSolute carrier organic anion transporter family member 1A2transporter
ProbenecidMonocarboxylate transporter 1transporter
ProbenecidSodium/bile acid cotransportertransporter
ProbenecidSolute carrier family 22 member 6transporter
ProbenecidSolute carrier family 22 member 10transporter
ProbenecidSolute carrier family 22 member 8transporter
ProbenecidCanalicular multispecific organic anion transporter 1transporter
ProbenecidATP-binding cassette sub-family C member 11transporter
ProbenecidSolute carrier family 22 member 11transporter
ProbenecidSolute carrier organic anion transporter family member 1C1transporter
ProbenecidSolute carrier family 22 member 7transporter
ProbenecidSolute carrier family 22 member 6target
ProbenecidPannexin-1target
ProbenecidCytochrome P450 2C8enzyme
ProbenecidCytochrome P450 3A4enzyme
ProbenecidSolute carrier family 22 member 12transporter
ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
ProbenecidTaste receptor type 2 member 16target
ProbenecidUDP-glucuronosyltransferase 1-1enzyme
ProbenecidCytochrome P450 2C9enzyme
LumacaftorCytochrome P450 2B6enzyme
LumacaftorCytochrome P450 2C8enzyme
LumacaftorCytochrome P450 2C9enzyme
LumacaftorCytochrome P450 2C19enzyme
LumacaftorSerum albumincarrier
LumacaftorCystic fibrosis transmembrane conductance regulatortarget
LumacaftorCytochrome P450 3A4enzyme
LumacaftorP-glycoprotein 1transporter
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
IsavuconazoleCytochrome P450 3A4enzyme
IsavuconazoleCytochrome P450 3A5enzyme
IsavuconazoleCytochrome P450 2C8enzyme
IsavuconazoleCytochrome P450 2C9enzyme
IsavuconazoleCytochrome P450 2C19enzyme
IsavuconazoleCytochrome P450 2D6enzyme
IsavuconazoleCytochrome P450 2B6enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
IsavuconazoleP-glycoprotein 1transporter
IsavuconazoleATP-binding cassette sub-family G member 2transporter
IsavuconazoleSolute carrier family 22 member 2transporter
IsavuconazoleLanosterol 14-alpha demethylasetarget
IsavuconazolePotassium voltage-gated channel subfamily H member 2target
IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsavuconazoleG protein-activated inward rectifier potassium channel 2target
IsavuconazoleG protein-activated inward rectifier potassium channel 3target
IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
IsavuconazolePotassium voltage-gated channel subfamily A member 5target
IsavuconazolePotassium voltage-gated channel subfamily D member 3target
IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
IsavuconazoleSodium channel protein type 5 subunit alphatarget
Hydrocortisone aceponateAnnexin A1target
Hydrocortisone aceponateGlucocorticoid receptortarget
Hydrocortisone aceponateSex hormone-binding globulincarrier
Hydrocortisone aceponateCytochrome P450 3A4enzyme
Hydrocortisone aceponateCytochrome P450 3A5enzyme
Hydrocortisone aceponateCytochrome P450 3A7enzyme
Hydrocortisone aceponateP-glycoprotein 1transporter
Hydrocortisone aceponateSolute carrier organic anion transporter family member 1A2transporter
Hydrocortisone aceponateATP-binding cassette sub-family G member 2transporter
Hydrocortisone aceponateCytochrome P450 2C8enzyme
Hydrocortisone aceponateCorticosteroid-binding globulincarrier
Hydrocortisone aceponateCorticosteroid 11-beta-dehydrogenase isozyme 2target
Hydrocortisone aceponate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Hydrocortisone aceponateSolute carrier family 22 member 8transporter
Hydrocortisone acetateAnnexin A1target
Hydrocortisone acetateGlucocorticoid receptortarget
Hydrocortisone acetateSex hormone-binding globulincarrier
Hydrocortisone acetateCytochrome P450 3A4enzyme
Hydrocortisone acetateCytochrome P450 3A5enzyme
Hydrocortisone acetateCytochrome P450 3A7enzyme
Hydrocortisone acetateP-glycoprotein 1transporter
Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
Hydrocortisone acetateCytochrome P450 2C8enzyme
Hydrocortisone acetateCorticosteroid-binding globulincarrier
Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Hydrocortisone acetateSolute carrier family 22 member 8transporter
Hydrocortisone butyrateAnnexin A1target
Hydrocortisone butyrateGlucocorticoid receptortarget
Hydrocortisone butyrateSex hormone-binding globulincarrier
Hydrocortisone butyrateCytochrome P450 3A4enzyme
Hydrocortisone butyrateCytochrome P450 3A5enzyme
Hydrocortisone butyrateCytochrome P450 3A7enzyme
Hydrocortisone butyrateP-glycoprotein 1transporter
Hydrocortisone butyrateSolute carrier organic anion transporter family member 1A2transporter
Hydrocortisone butyrateATP-binding cassette sub-family G member 2transporter
Hydrocortisone butyrateCytochrome P450 11B1, mitochondrialenzyme
Hydrocortisone butyrateCytochrome P450 11B2, mitochondrialenzyme
Hydrocortisone butyrateCytochrome P450 2C8enzyme
Hydrocortisone butyrateCorticosteroid-binding globulincarrier
Hydrocortisone butyrateCorticosteroid 11-beta-dehydrogenase isozyme 2target
Hydrocortisone butyrate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Hydrocortisone butyrateSolute carrier family 22 member 8transporter
Hydrocortisone cypionateAnnexin A1target
Hydrocortisone cypionateGlucocorticoid receptortarget
Hydrocortisone cypionateSex hormone-binding globulincarrier
Hydrocortisone cypionateCytochrome P450 3A4enzyme
Hydrocortisone cypionateCytochrome P450 3A5enzyme
Hydrocortisone cypionateCytochrome P450 3A7enzyme
Hydrocortisone cypionateP-glycoprotein 1transporter
Hydrocortisone cypionateSolute carrier organic anion transporter family member 1A2transporter
Hydrocortisone cypionateATP-binding cassette sub-family G member 2transporter
Hydrocortisone cypionateCytochrome P450 2C8enzyme
Hydrocortisone cypionateCorticosteroid-binding globulincarrier
Hydrocortisone cypionateCorticosteroid 11-beta-dehydrogenase isozyme 2target
Hydrocortisone cypionate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Hydrocortisone cypionateSolute carrier family 22 member 8transporter
Hydrocortisone phosphateAnnexin A1target
Hydrocortisone phosphateGlucocorticoid receptortarget
Hydrocortisone phosphateSex hormone-binding globulincarrier
Hydrocortisone phosphateCytochrome P450 3A4enzyme
Hydrocortisone phosphateCytochrome P450 3A5enzyme
Hydrocortisone phosphateCytochrome P450 3A7enzyme
Hydrocortisone phosphateP-glycoprotein 1transporter
Hydrocortisone phosphateSolute carrier organic anion transporter family member 1A2transporter
Hydrocortisone phosphateATP-binding cassette sub-family G member 2transporter
Hydrocortisone phosphateCytochrome P450 2C8enzyme
Hydrocortisone phosphateCorticosteroid-binding globulincarrier
Hydrocortisone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2target
Hydrocortisone phosphate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Hydrocortisone phosphateSolute carrier family 22 member 8transporter
Hydrocortisone probutateAnnexin A1target
Hydrocortisone probutateGlucocorticoid receptortarget
Hydrocortisone probutateSex hormone-binding globulincarrier
Hydrocortisone probutateCytochrome P450 3A4enzyme
Hydrocortisone probutateCytochrome P450 3A5enzyme
Hydrocortisone probutateCytochrome P450 3A7enzyme
Hydrocortisone probutateP-glycoprotein 1transporter
Hydrocortisone probutateSolute carrier organic anion transporter family member 1A2transporter
Hydrocortisone probutateATP-binding cassette sub-family G member 2transporter
Hydrocortisone probutateCytochrome P450 11B1, mitochondrialenzyme
Hydrocortisone probutateCytochrome P450 11B2, mitochondrialenzyme
Hydrocortisone probutateCytochrome P450 2C8enzyme
Hydrocortisone probutateCorticosteroid-binding globulincarrier
Hydrocortisone probutateCorticosteroid 11-beta-dehydrogenase isozyme 2target
Hydrocortisone probutate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Hydrocortisone probutateSolute carrier family 22 member 8transporter
Hydrocortisone valerateAnnexin A1target
Hydrocortisone valerateGlucocorticoid receptortarget
Hydrocortisone valerateSex hormone-binding globulincarrier
Hydrocortisone valerateCytochrome P450 3A4enzyme
Hydrocortisone valerateCytochrome P450 3A5enzyme
Hydrocortisone valerateCytochrome P450 3A7enzyme
Hydrocortisone valerateP-glycoprotein 1transporter
Hydrocortisone valerateSolute carrier organic anion transporter family member 1A2transporter
Hydrocortisone valerateATP-binding cassette sub-family G member 2transporter
Hydrocortisone valerateCytochrome P450 11B1, mitochondrialenzyme
Hydrocortisone valerateCytochrome P450 11B2, mitochondrialenzyme
Hydrocortisone valerateCytochrome P450 2C8enzyme
Hydrocortisone valerateCorticosteroid-binding globulincarrier
Hydrocortisone valerateCorticosteroid 11-beta-dehydrogenase isozyme 2target
Hydrocortisone valerate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
Hydrocortisone valerateSolute carrier family 22 member 8transporter
IvosidenibIsocitrate dehydrogenase [NADP] cytoplasmictarget
IvosidenibCytochrome P450 3A4enzyme
IvosidenibCytochrome P450 2B6enzyme
IvosidenibCytochrome P450 2C9enzyme
IvosidenibCytochrome P450 2C8enzyme
IvosidenibSolute carrier family 22 member 8transporter
IvosidenibP-glycoprotein 1transporter
Hydrocortisone succinateCytochrome P450 3A4enzyme
Hydrocortisone succinateCytochrome P450 2C8enzyme
Hydrocortisone succinateCytochrome P450 11B1, mitochondrialenzyme
Hydrocortisone succinateCytochrome P450 11B2, mitochondrialenzyme
RifamycinCytochrome P450 3A4enzyme
RifamycinCytochrome P450 2C19enzyme
RifamycinCytochrome P450 2B6enzyme
RifamycinCytochrome P450 2C8enzyme
RifamycinCytochrome P450 2C9enzyme
RifamycinSolute carrier organic anion transporter family member 1A2transporter
RifamycinSolute carrier organic anion transporter family member 1B1transporter
RifamycinSolute carrier organic anion transporter family member 1B3transporter
RifamycinSolute carrier organic anion transporter family member 2A1transporter
RifamycinSolute carrier organic anion transporter family member 2B1transporter
RifamycinSerum albumincarrier
RifamycinDNA-directed RNA polymerase subunit betatarget
RifamycinDNA-directed RNA polymerase subunit alphatarget
RifamycinDNA-directed RNA polymerase subunit beta'target
RifamycinMultidrug and toxin extrusion protein 1transporter
RifamycinCytochrome P450 1A2enzyme
RifamycinP-glycoprotein 1transporter
GriseofulvinTubulin beta chaintarget
GriseofulvinKeratin, type I cytoskeletal 12target
GriseofulvinCytochrome P450 1A2enzyme
GriseofulvinCytochrome P450 3A4enzyme
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneP-glycoprotein 1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneSolute carrier family 22 member 8transporter
Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PhenobarbitalCytochrome P450 2C19enzyme
PhenobarbitalCytochrome P450 2C9enzyme
PhenobarbitalCytochrome P450 2B6enzyme
PhenobarbitalCytochrome P450 2C8enzyme
PhenobarbitalCytochrome P450 1A2enzyme
PhenobarbitalCytochrome P450 3A4enzyme
PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
PhenobarbitalBile salt export pumptransporter
PhenobarbitalP-glycoprotein 1transporter
PhenobarbitalMultidrug resistance-associated protein 1transporter
PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PhenobarbitalGlutamate receptor 2target
PhenobarbitalGlutamate receptor ionotropic, kainate 2target
PhenobarbitalCytochrome P450 2A6enzyme
PhenobarbitalCytochrome P450 2E1enzyme
PhenobarbitalCytochrome P450 3A5enzyme
PhenobarbitalCytochrome P450 1A1enzyme
PhenobarbitalCytochrome P450 2C18enzyme
PhenobarbitalCytochrome P450 3A7enzyme
PhenobarbitalCytochrome P450 4B1enzyme
PhenobarbitalNMDA receptortarget
PhenobarbitalNuclear receptor subfamily 1 group I member 2target
PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
RifaximinDNA-directed RNA polymerase subunit betatarget
RifaximinNuclear receptor subfamily 1 group I member 2target
RifaximinCytochrome P450 3A4enzyme
RifaximinCytochrome P450 2C19enzyme
RifaximinCytochrome P450 2C8enzyme
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
CenobamateUDP-glucuronosyltransferase 2B7enzyme
CenobamateUDP-glucuronosyltransferase 2B4enzyme
CenobamateCytochrome P450 2E1enzyme
CenobamateCytochrome P450 2A6enzyme
CenobamateCytochrome P450 2B6enzyme
CenobamateCytochrome P450 2C19enzyme
CenobamateCytochrome P450 3A4enzyme
CenobamateCytochrome P450 3A5enzyme
CenobamateSerum albumincarrier
CenobamateCytochrome P450 2C8enzyme
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneP-glycoprotein 1transporter
BetamethasoneCytochrome P450 19A1enzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneSerum albumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
Prednisolone phosphateCytochrome P450 3A4enzyme
Prednisolone phosphateCytochrome P450 3A5enzyme
Prednisolone phosphateCytochrome P450 3A Subfamilyenzyme
Prednisolone phosphateCytochrome P450 2A6enzyme
Prednisolone phosphateCytochrome P450 1B1enzyme
Prednisolone phosphateCytochrome P450 2B6enzyme
Prednisolone phosphateCytochrome P450 2C8enzyme
Prednisolone phosphateCytochrome P450 2C9enzyme
Prednisolone phosphateCytochrome P450 2C19enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Prednisolone phosphateGlucocorticoid receptortarget
Prednisolone phosphateAnnexin A1target
Prednisolone phosphateSolute carrier organic anion transporter family member 1A2transporter
Prednisolone phosphateP-glycoprotein 1transporter
Prednisolone phosphateSolute carrier family 22 member 8transporter
Prednisolone phosphateCorticosteroid-binding globulincarrier
Prednisolone phosphateSerum albumincarrier
Dexamethasone acetateGlucocorticoid receptortarget
Dexamethasone acetateAnnexin A1target
Dexamethasone acetateNitric oxide synthase, inducibletarget
Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
Dexamethasone acetateCytochrome P450 3A4enzyme
Dexamethasone acetateCytochrome P450 3A5enzyme
Dexamethasone acetateCytochrome P450 3A7enzyme
Dexamethasone acetateBile salt export pumptransporter
Dexamethasone acetateP-glycoprotein 1transporter
Dexamethasone acetateCanalicular multispecific organic anion transporter 1transporter
Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
Dexamethasone acetateATP-binding cassette sub-family G member 2transporter
Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Dexamethasone acetateCytochrome P450 1A1enzyme
Dexamethasone acetateCytochrome P450 2A6enzyme
Dexamethasone acetateCytochrome P450 2B6enzyme
Dexamethasone acetateCytochrome P450 2C19enzyme
Dexamethasone acetateCytochrome P450 2C8enzyme
Dexamethasone acetateCytochrome P450 2E1enzyme
Dexamethasone acetateCytochrome P450 3A43enzyme
Dexamethasone acetateCytochrome P450 4A11enzyme
Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
Dexamethasone acetateSerum albumincarrier
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Dexamethasone acetateSolute carrier family 22 member 8transporter
PralsetinibProto-oncogene tyrosine-protein kinase receptor Rettarget
PralsetinibEpithelial discoidin domain-containing receptor 1target
PralsetinibNT-3 growth factor receptortarget
PralsetinibReceptor-type tyrosine-protein kinase FLT3target
PralsetinibTyrosine-protein kinase JAK1target
PralsetinibTyrosine-protein kinase JAK2target
PralsetinibHigh affinity nerve growth factor receptortarget
PralsetinibVascular endothelial growth factor receptor 2target
PralsetinibPlatelet-derived growth factor receptor betatarget
PralsetinibFibroblast growth factor receptor 1target
PralsetinibFibroblast growth factor receptor 2target
PralsetinibCytochrome P450 3A4enzyme
PralsetinibCytochrome P450 3A5enzyme
PralsetinibCytochrome P450 2D6enzyme
PralsetinibCytochrome P450 1A2enzyme
PralsetinibCytochrome P450 2C8enzyme
PralsetinibCytochrome P450 2C9enzyme
PralsetinibP-glycoprotein 1transporter
PralsetinibATP-binding cassette sub-family G member 2transporter
PralsetinibSolute carrier organic anion transporter family member 1B1transporter
PralsetinibSolute carrier organic anion transporter family member 1B3transporter
PralsetinibSolute carrier family 22 member 6transporter
PralsetinibMultidrug and toxin extrusion protein 1transporter
PralsetinibMultidrug and toxin extrusion protein 2transporter
PralsetinibBile salt export pumptransporter