Cytochrome P-450 CYP2E1 Inducers (strength unknown)

Name
Cytochrome P-450 CYP2E1 Inducers (strength unknown)
Accession Number
DBCAT004496
Description

Not Available

Drugs
DrugDrug Description
NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
ClofibrateA fibric acid derivative used to treat hypertriglyceridemia and high cholesterol.
PhenelzineA monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
IsoniazidAn antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
ColchicineAn alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
RifampinAn antibiotic used alone or in combination with other antimicrobial drugs to treat tuberculosis and asymptomatic carriers of Neisseria meningitidis.
StreptozocinA nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma.
PiperaquineFor the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
FomepizoleAn inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
PrimidoneAn antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
Drugs & Drug Targets
DrugTargetType
NicotineNeuronal acetylcholine receptor subunit alpha-2target
NicotineNeuronal acetylcholine receptor subunit beta-2target
NicotineNeuronal acetylcholine receptor subunit alpha-7target
NicotineNeuronal acetylcholine receptor subunit alpha-4target
NicotineNeuronal acetylcholine receptor subunit alpha-10target
NicotineNeuronal acetylcholine receptor subunit alpha-9target
NicotineCytochrome P450 2A6enzyme
NicotineCytochrome P450 2E1enzyme
NicotineCytochrome P450 2A13enzyme
NicotineCytochrome P450 2B6enzyme
NicotineNeuronal acetylcholine receptor subunit beta-4target
NicotineNeuronal acetylcholine receptor subunit alpha-3target
NicotineNeuronal acetylcholine receptor subunit alpha-5target
NicotineNeuronal acetylcholine receptor subunit alpha-6target
NicotineNeuronal acetylcholine receptor subunit beta-3target
NicotineSolute carrier family 22 member 2transporter
NicotineSolute carrier family 22 member 1transporter
NicotineSolute carrier family 22 member 3transporter
NicotineOrganic cation/carnitine transporter 2transporter
NicotineSolute carrier family 22 member 4transporter
NicotineCytochrome P450 1A1enzyme
NicotineCytochrome P450 1A2enzyme
NicotineCytochrome P450 2C19enzyme
NicotineCytochrome P450 2C8enzyme
NicotineCytochrome P450 2C9enzyme
NicotineCytochrome P450 2D6enzyme
NicotineCytochrome P450 3A4enzyme
NicotineAmine oxidase [flavin-containing] Aenzyme
NicotineAmine oxidase [flavin-containing] Benzyme
NicotineAromatasetarget
NicotineCholine O-acetyltransferasetarget
ClofibratePeroxisome proliferator-activated receptor alphatarget
ClofibrateCytochrome P450 3A4enzyme
ClofibrateGlutathione S-transferase A2enzyme
ClofibrateCytochrome P450 2E1enzyme
ClofibrateCytochrome P450 1A1enzyme
ClofibrateCytochrome P450 4A11enzyme
ClofibrateThyroxine-binding globulincarrier
ClofibrateLipoprotein lipasetarget
PhenelzineAmine oxidase [copper-containing] 3target
PhenelzineAmine oxidase [flavin-containing] Btarget
PhenelzineAmine oxidase [flavin-containing] Atarget
PhenelzineAmine oxidase [flavin-containing] Aenzyme
PhenelzineAmine oxidase [flavin-containing] Benzyme
PhenelzineCytochrome P450 2E1enzyme
Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
PhenelzineGlutamic acid decarboxylasetarget
PhenelzineAlanine aminotransferase 1target
PhenelzineAlanine aminotransferase 2target
PhenelzineCytochrome P450 2C19enzyme
PhenelzineCytochrome P450 2C8enzyme
PhenelzineCytochrome P450 3A4enzyme
PhenelzineCytochrome P450 3A5enzyme
PhenelzineCytochrome P450 3A7enzyme
PhenelzineCytochrome P450 2D6enzyme
PhenelzineCytochrome P450 3A Subfamilyenzyme
IsoniazidCatalase-peroxidasetarget
IsoniazidEnoyl-[acyl-carrier-protein] reductase [NADH]target
IsoniazidCytochrome P450 2E1enzyme
IsoniazidCytochrome P450 1A2enzyme
IsoniazidCytochrome P450 2C9enzyme
IsoniazidCytochrome P450 2D6enzyme
IsoniazidCytochrome P450 2C19enzyme
IsoniazidArylamine N-acetyltransferase 2enzyme
IsoniazidArylamine N-acetyltransferaseenzyme
IsoniazidCytochrome P450 2A6enzyme
IsoniazidCytochrome P450 2C8enzyme
IsoniazidCytochrome P450 2C8target
IsoniazidCytochrome P450 1A2target
IsoniazidCytochrome P450 3A4target
IsoniazidCytochrome P450 2C19target
IsoniazidDihydrofolate reductasetarget
IsoniazidAlbumincarrier
IsoniazidCytochrome P450 3A4enzyme
ColchicineTubulin beta chaintarget
ColchicineCytochrome P450 3A4enzyme
ColchicineATP-dependent translocase ABCB1transporter
ColchicineCytochrome P450 2B6enzyme
ColchicineCytochrome P450 2C8enzyme
ColchicineCytochrome P450 2E1enzyme
ColchicineAlbumincarrier
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneATP-dependent translocase ABCB1transporter
DexamethasoneATP-binding cassette sub-family C member 2transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneAlbumincarrier
Dexamethasone11-beta-hydroxysteroid dehydrogenase type 2enzyme
Dexamethasone11-beta-hydroxysteroid dehydrogenase 1enzyme
DexamethasoneOrganic anion transporter 3transporter
GlycerinGroup IIE secretory phospholipase A2target
GlycerinInositol-3-phosphate synthase 1target
GlycerinAll-trans-retinol dehydrogenase [NAD(+)] ADH1Btarget
GlycerinInositol 1,4,5-trisphosphate-gated calcium channel ITPR1target
GlycerinGlycodelintarget
GlycerinAlpha-N-acetylgalactosaminidasetarget
GlycerinADP-ribosylation factor 1target
GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
GlycerinDNA mismatch repair protein MutLtarget
GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
GlycerinAdenine DNA glycosylasetarget
GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
GlycerinCytochrome P450 2E1enzyme
GlycerinAldehyde dehydrogenase 1A1enzyme
GlycerinPeroxisome proliferator-activated receptor deltatarget
GlycerinMaleylacetoacetate isomerasetarget
GlycerinAquaporin-7transporter
GlycerinAquaporin-9transporter
GlycerinGlycerol uptake facilitator proteintransporter
PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PhenobarbitalCytochrome P450 2C19enzyme
PhenobarbitalCytochrome P450 2C9enzyme
PhenobarbitalCytochrome P450 2B6enzyme
PhenobarbitalCytochrome P450 2C8enzyme
PhenobarbitalCytochrome P450 1A2enzyme
PhenobarbitalCytochrome P450 3A4enzyme
PhenobarbitalATP-binding cassette sub-family C member 3transporter
PhenobarbitalBile salt export pumptransporter
PhenobarbitalATP-dependent translocase ABCB1transporter
PhenobarbitalMultidrug resistance-associated protein 1transporter
PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
PhenobarbitalATP-binding cassette sub-family C member 2transporter
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PhenobarbitalGlutamate receptor 2target
PhenobarbitalGlutamate receptor ionotropic, kainate 2target
PhenobarbitalCytochrome P450 2A6enzyme
PhenobarbitalCytochrome P450 2E1enzyme
PhenobarbitalCytochrome P450 3A5enzyme
PhenobarbitalCytochrome P450 1A1enzyme
PhenobarbitalCytochrome P450 2C18enzyme
PhenobarbitalCytochrome P450 3A7enzyme
PhenobarbitalCytochrome P450 4B1enzyme
PhenobarbitalNMDA receptortarget
PhenobarbitalNuclear receptor subfamily 1 group I member 2target
PhenobarbitalUDP-glucuronosyltransferase 1A1enzyme
PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
RifampinNuclear receptor subfamily 1 group I member 2target
RifampinCytochrome P450 3A4enzyme
RifampinCytochrome P450 1A2enzyme
RifampinCytochrome P450 2C8enzyme
RifampinUDP-glucuronosyltransferase 1A1enzyme
RifampinCytochrome P450 2C9enzyme
RifampinCytochrome P450 2B6enzyme
RifampinCytochrome P450 2C19enzyme
RifampinATP-binding cassette sub-family C member 3transporter
RifampinATP-binding cassette sub-family C member 5transporter
RifampinATP-dependent translocase ABCB1transporter
RifampinATP-binding cassette sub-family C member 2transporter
RifampinSolute carrier organic anion transporter family member 2B1transporter
RifampinBile salt export pumptransporter
RifampinMultidrug resistance-associated protein 1transporter
RifampinSolute carrier organic anion transporter family member 1A2transporter
RifampinSolute carrier organic anion transporter family member 1B3transporter
RifampinSolute carrier family 22 member 7transporter
RifampinSolute carrier organic anion transporter family member 1B1transporter
RifampinCytochrome P450 2A6enzyme
RifampinCytochrome P450 2E1enzyme
RifampinCytochrome P450 3A43enzyme
RifampinCytochrome P450 3A7enzyme
RifampinSolute carrier family 22 member 6transporter
RifampinOrganic anion transporter 3transporter
RifampinUDP-glucuronosyltransferase 1A9enzyme
RifampinCytochrome P450 3A5enzyme
RifampinAlbumincarrier
Rifampinalpha1-acid glycoproteincarrier
RifampinDNA-directed RNA polymerase subunit betatarget
StreptozocinDNAtarget
StreptozocinATP-dependent translocase ABCB1transporter
StreptozocinSolute carrier family 2, facilitated glucose transporter member 2target
StreptozocinO-GlcNAcase BT_4395target
StreptozocinCytochrome P450 1A1enzyme
StreptozocinCytochrome P450 1A2enzyme
StreptozocinCytochrome P450 2E1enzyme
StreptozocinProtein O-GlcNAcasetarget
PiperaquineCytochrome P450 3A4enzyme
PiperaquineCytochrome P450 2C19enzyme
PiperaquineCytochrome P450 2C9enzyme
PiperaquineCytochrome P450 2B6enzyme
PiperaquineCytochrome P450 2E1enzyme
FomepizoleAlcohol dehydrogenase 1Atarget
FomepizoleAll-trans-retinol dehydrogenase [NAD(+)] ADH1Btarget
FomepizoleAlcohol dehydrogenase 1Ctarget
FomepizoleCatalasetarget
FomepizoleCytochrome P450 2E1enzyme
FomepizoleCytochrome P450 2A6enzyme
PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
PrimidoneCytochrome P450 2C19enzyme
PrimidoneCytochrome P450 2C9enzyme
PrimidoneCytochrome P450 3A4enzyme
PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
PrimidoneGlutamate receptor 2target
PrimidoneGlutamate receptor ionotropic, kainate 2target
PrimidoneGABA(A) Receptortarget
PrimidoneTransient receptor potential cation channel subfamily M member 3transporter
PrimidoneCytochrome P450 2E1enzyme
PrimidoneCytochrome P450 1A2enzyme
PrimidoneUDP-glucuronosyltransferases (UGTs)enzyme
Dexamethasone acetateGlucocorticoid receptortarget
Dexamethasone acetateAnnexin A1target
Dexamethasone acetateNitric oxide synthase, inducibletarget
Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
Dexamethasone acetateCytochrome P450 3A4enzyme
Dexamethasone acetateCytochrome P450 3A5enzyme
Dexamethasone acetateCytochrome P450 3A7enzyme
Dexamethasone acetateBile salt export pumptransporter
Dexamethasone acetateATP-dependent translocase ABCB1transporter
Dexamethasone acetateATP-binding cassette sub-family C member 2transporter
Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
Dexamethasone acetateBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Dexamethasone acetateCytochrome P450 1A1enzyme
Dexamethasone acetateCytochrome P450 2A6enzyme
Dexamethasone acetateCytochrome P450 2B6enzyme
Dexamethasone acetateCytochrome P450 2C19enzyme
Dexamethasone acetateCytochrome P450 2C8enzyme
Dexamethasone acetateCytochrome P450 2E1enzyme
Dexamethasone acetateCytochrome P450 3A43enzyme
Dexamethasone acetateCytochrome P450 4A11enzyme
Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
Dexamethasone acetateAlbumincarrier
Dexamethasone acetate11-beta-hydroxysteroid dehydrogenase type 2enzyme
Dexamethasone acetate11-beta-hydroxysteroid dehydrogenase 1enzyme
Dexamethasone acetateOrganic anion transporter 3transporter