Agents used to treat hypothyroidism

Name
Agents used to treat hypothyroidism
Accession Number
DBCAT004965
Description

Agents used to treat hypothyroidism or underactive thyroid gland.

Drugs
DrugDrug Description
LevothyroxineA synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.
LiotrixMay be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic...
TiratricolA metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.
LiothyronineA thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism.
Thyrotropin alfaA recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue.
Thyroid, porcineA naturally-occurring peptide hormone used for the replacement therapy for hypothyroidism of any etiology, treatment for euthyroid goiters, and management of thyroid cancers.
Drugs & Drug Targets
DrugTargetType
LevothyroxineThyroid hormone receptor alphatarget
LevothyroxineThyroid hormone receptor betatarget
LevothyroxineCytochrome P450 2C8enzyme
LevothyroxineTransthyretincarrier
LevothyroxineSerum albumincarrier
LevothyroxineThyroxine-binding globulincarrier
LevothyroxineP-glycoprotein 1transporter
LevothyroxineMonocarboxylate transporter 8transporter
LevothyroxineSolute carrier organic anion transporter family member 1C1transporter
LevothyroxineSolute carrier organic anion transporter family member 1A2transporter
LevothyroxineSolute carrier organic anion transporter family member 1B1transporter
LevothyroxineSolute carrier organic anion transporter family member 1B3transporter
LevothyroxineSolute carrier organic anion transporter family member 4A1transporter
LevothyroxineLarge neutral amino acids transporter small subunit 1transporter
LevothyroxineUDP-glucuronosyltransferase 1-1enzyme
LevothyroxineSolute carrier organic anion transporter family member 2B1transporter
LevothyroxineIntegrin alpha-Vtarget
LevothyroxineIntegrin beta-3target
LevothyroxineP-glycoprotein 1enzyme
LiotrixThyroid hormone receptor alphatarget
LiotrixThyroid hormone receptor betatarget
LiotrixCytochrome P450 2C8enzyme
LiotrixSolute carrier organic anion transporter family member 1A2transporter
LiotrixSolute carrier organic anion transporter family member 1B1transporter
LiotrixSolute carrier organic anion transporter family member 1B3transporter
LiotrixSolute carrier organic anion transporter family member 4C1transporter
LiotrixSodium/bile acid cotransportertransporter
LiotrixSolute carrier organic anion transporter family member 1C1transporter
LiotrixSolute carrier organic anion transporter family member 4A1transporter
LiotrixSolute carrier family 22 member 8transporter
LiotrixMonocarboxylate transporter 8transporter
LiotrixMonocarboxylate transporter 10transporter
LiotrixP-glycoprotein 1transporter
LiotrixTransthyretincarrier
LiotrixThyroxine-binding globulincarrier
LiotrixSerum albumincarrier
LiotrixCytochrome P450 3A4enzyme
TiratricolThyroid hormone receptor betatarget
LiothyronineThyroid hormone receptor betatarget
LiothyronineThyroid hormone receptor alphatarget
LiothyronineThyroxine-binding globulincarrier
LiothyronineTransthyretincarrier
LiothyronineSerum albumincarrier
LiothyronineP-glycoprotein 1transporter
LiothyronineSolute carrier family 22 member 8transporter
LiothyronineMonocarboxylate transporter 10transporter
LiothyronineSolute carrier organic anion transporter family member 4A1transporter
LiothyronineSolute carrier organic anion transporter family member 1C1transporter
LiothyronineSolute carrier organic anion transporter family member 1A2transporter
LiothyronineSodium/bile acid cotransportertransporter
LiothyronineSolute carrier organic anion transporter family member 4C1transporter
LiothyronineSolute carrier organic anion transporter family member 1B3transporter
LiothyronineSolute carrier organic anion transporter family member 1B1transporter
LiothyronineLarge neutral amino acids transporter small subunit 1transporter
LiothyronineProliferating cell nuclear antigentarget
LiothyronineUDP-glucuronosyltransferase 1-1enzyme
Thyrotropin alfaThyrotropin receptortarget
Thyroid, porcineThyroxine-binding globulincarrier
Thyroid, porcineSerum albumincarrier
Thyroid, porcineTransthyretincarrier
Thyroid, porcineMonocarboxylate transporter 8transporter
Thyroid, porcineSolute carrier organic anion transporter family member 1C1transporter
Thyroid, porcineSolute carrier organic anion transporter family member 3A1transporter
Thyroid, porcineSolute carrier organic anion transporter family member 4A1transporter
Thyroid, porcineLarge neutral amino acids transporter small subunit 1transporter
Thyroid, porcineSodium/bile acid cotransportertransporter
Thyroid, porcineType I iodothyronine deiodinaseenzyme
Thyroid, porcineType II iodothyronine deiodinaseenzyme
Thyroid, porcineThyroxine 5-deiodinaseenzyme
Thyroid, porcineThyroid hormone receptor alphatarget
Thyroid, porcineThyroid hormone receptor betatarget
Thyroid, porcineSulfotransferase 1A1enzyme
Thyroid, porcineSulfotransferase 1A2enzyme
Thyroid, porcineSulfotransferase 1A3/1A4enzyme
Thyroid, porcineSulfotransferase family cytosolic 1B member 1enzyme
Thyroid, porcineSulfotransferase 1C2enzyme
Thyroid, porcineEstrogen sulfotransferaseenzyme