Indolizidines

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DBCAT005569Pharmacologic class

Saturated indolizines that are fused six and five-membered rings with a nitrogen atom at the ring fusion. They are biosynthesized in PLANTS by cyclization of a LYSINE coupled to ACETYL COENZYME A. A DrugBank category of 43 drugs. 14 of them are approved.

Drugs

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What you can answer from here — as of January 13, 2022

43DrugsEach linked to its full drug card
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100Drug targetsEvery drug–target pair in the class, with bond type
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399Marketed productsAcross the regions we cover, with dosage forms and routes
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6Routes of administrationHow the drugs in this class are given
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Which targets do Indolizidines share, and which companies have late-stage candidates in this class?

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