Nucleic Acid-Based Vaccines

Name
Nucleic Acid-Based Vaccines
Accession Number
DBCAT005632
Description

Vaccines formulated with nucleic acids specific for a target antigen. They are designed to induce antibody production against the target by host.

Drugs
DrugDrug Description
Moderna COVID-19 VaccineAn mRNA vaccine for the prevention of COVID-19 caused by the SARS-CoV-2 virus.
AstraZeneca COVID-19 VaccineA two-dose replication-deficient adenovirus vector vaccine used to prevent COVID-19 caused by SARS-CoV-2.
BNT162b1 SARS-CoV-2 VaccineBNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding...
TozinameranAn mRNA vaccine for the prevention of COVID-19 caused by the SARS-CoV-2 virus.
Bizalimogene ralaplasmidBizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related Anal or Anal/peri-anal, High Grade...
PidacmeranPidacmeran is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).
BNT-162A1BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).
GI-6207Not Annotated
INO-4800INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that...
CVnCoV VaccineThe CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate...
Rocakinogene sifuplasmidRocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma (GBM)).
FamtozinameranA component of a bivalent COVID-19 mRNA vaccine encoding the viral spike protein of Omicron variant lineages BA.4 and BA.5.
mRNA-1345mRNA-1345 is an investigational RSV vaccine.
Modified vaccinia virus Ankara-85A antigenModified vaccinia virus Ankara-85A antigen is under investigation in clinical trial NCT00953927 (A Study of MVA85A in Healthy Infants).
OXB-301OXB-301 is under investigation in clinical trial NCT00397345 (Trovax Renal Immunotherapy Survival Trial).
Drugs & Drug Targets
DrugTargetType