Adrenergic alpha-Agonists
- Name
- Adrenergic alpha-Agonists
- Accession Number
- DBCAT000536
- Description
Drugs that selectively bind to and activate alpha adrenergic receptors.
- Drugs
Drug Drug Description 4-Bromo-2,5-dimethoxyphenethylamine Not Available 4-Methoxyamphetamine Not Available Adrafinil Used to relieve excessive sleepiness and inattention in elderly patients. Amidephrine A sympathomimetic indicated in the treatment of acute, chronic, vasomotor, and allergic rhinitis. Amitraz Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as... Apraclonidine An alpha adrenergic agonist used to treat raised intraocular pressure. Azepexole Azepexole is a small molecule drug. Azepexole has a monoisotopic molecular weight of 181.12 Da. Benzphetamine A sympathomimetic used to manage exogenous obesity short term. Bethanidine For the treatment of hypertension. Brimonidine An alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea. Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. Cirazoline Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed... Clonidine An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. Detomidine Used as a large animal sedative, primarily in horses. Dexmedetomidine An alpha-2 agonist used for sedation during various procedures. Dipivefrin A prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma. DL-Methylephedrine Used as an antitussive and decongestant . Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. Ephedra sinica root An alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest. Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Ergometrine An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. Etilefrine An adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive. Etomidate A short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. Guanabenz An alpha-2 adrenergic agonist used to treat hypertension. Guanfacine An alpha-2A adrenergic receptor agonist used to treat ADHD. Indanidine Indanidine is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Indanidine is a a2 adrenoreceptor agonist. Indanidine has a monoisotopic molecular weight... Isometheptene A sympathomimetic used to relieve painful spasms in combination with other agents such as caffeine and metamizole. Lofexidine A centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults. Medetomidine Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist.... Mephentermine A sympathomimetic agent used in the treatment of hypotension. Metamfetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. Metaraminol For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage Methoxamine An alpha adrenergic agonist used to treat hypotension. Methyldopa A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. Midodrine An alpha-adrenergic agonist used to treat orthostatic hypotension. Mivazerol Mivazerol is a small molecule drug. Mivazerol has a monoisotopic molecular weight of 217.09 Da. Moxonidine An imidazoline/α-2 receptor agonist used to treat hypertension, especially in cases where ACE inhibitors, β-blockers, calcium channel blockers, and thiazides are not appropriate or provide inadequate blood pressure control. Naphazoline A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion. Norepinephrine A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. Norfenefrine Not Annotated Octopamine Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as... Oxymetazoline An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. Pergolide A long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy. Phendimetrazine A sympathomimetic amine used as adjunct therapy for the short term management of exogenous obesity. Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Phenylpropanolamine A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy. Propylhexedrine It is used to provide temporary symptomatic relief of nasal congestion due to colds, allergies and allergic rhinitis. Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Racephedrine Not Annotated Racepinephrine A bronchodilator used to treat intermittent asthma. Rilmenidine An I1-imidazoline receptor agonist used to treat hypertension. Romifidine Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species.... Synephrine Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... Talipexole Talipexole is a small molecule drug. Talipexole has a monoisotopic molecular weight of 209.1 Da. Tetryzoline An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion. Tizanidine An alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity. Xylazine A non-opioid and clonidine analog with analgesic and muscle relaxant properties used as a tranquilizer used in veterinary medicine. Xylometazoline A direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. - Drugs & Drug Targets