Hypothyroidism (DBCOND0009036)

Identifiers

Synonyms
Hypothyroid / Hypothyroidism, unspecified / Hypothyroidism (disorder) / Unspecified hypothyroidism / Thyroid activity decreased / Hypothyreosis

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Lactose
An additive and filler found in various products to maintain structure and consistency.
Levothyroxine
A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.
Liothyronine
A thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism.
Potassium Iodide
An oral antithyroid agent used for the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency.
Prothrombin
A coagulation factor used for emergency reversal of vitamin K antagonist therapy.
Thyroid, porcine
A naturally-occurring peptide hormone used for the replacement therapy for hypothyroidism of any etiology, treatment for euthyroid goiters, and management of thyroid cancers.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00403390
Generic vs. Name-Brand LevothyroxinetreatmentNot Availablecompleted
NCT05712421
A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidismtreatment2enrolling_by_invitation
NCT02364102
Effect of Hypothyroidism on Brown Adipose TissueNo drug interventionsNot AvailableNot Availablecompleted
NCT00005184
Immunogenetic Factors of Coronary Heart DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01997554
Validation of a New TSH TestNo drug interventionsdiagnosticNot Availablecompleted
NCT02567877
Is Levothyroxine Alone Adequate Thyroid Hormone Replacement?Not AvailableNot Availableterminated
NCT04795947
Correlation Between Thyroid Function and Quality of Life in HypothyroidismNo drug interventionsNot AvailableNot Availableunknown_status
NCT03627611
Identification of Non-responders to Levothyroxine Therapytreatment2completed
NCT05240911
Individual Dosing of Levothyroxine After ThyroidectomytreatmentNot Availableunknown_status
NCT06455371
Patient-centered Dosage of LevothyroxineNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01848171
Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidismtreatment4unknown_status
NCT02499471
Brown Adipose Tissue Activity and Thyroid HormoneNo drug interventionsbasic_scienceNot Availablecompleted
NCT03631771
Pediatric Risk of Hypothyroidism With Iodinated Contrast Mediaother4withdrawn
NCT01536678
Bioequivalence of Two Levothyroxine Tablet Formulations in Healthy Indian VolunteersNot Available4completed
NCT02512978
Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction(ThyroHeart-AMI)treatment4unknown_status
NCT05733078
Effect of Vitamin C Supplementation in Patients With Primary Hypothyroidismtreatment2recruiting
NCT03977207
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis PatientstreatmentNot Availablerecruiting
NCT06408909
Pharmacist Role in Thyroid DisordersNo drug interventionshealth_services_researchNot Availablecompleted
NCT05708456
The Effect of Mobile Application on Hypothyroid PatientsNo drug interventionssupportive_careNot Availablerecruiting
NCT04782856
Energy Metabolism in Thyroidectomized Patientstreatment2completed
NCT03926585
Variations in the DIO2 and MCT10 Genes and Effect of Triiodothyronine TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02548715
Levothyroxine Treatment for Subclinical Hypothyroidism After Head and Neck Surgerytreatment2 / 3withdrawn
NCT01921452
Study to Verify Clinical Utility of Point-of-Care (POC) Thyroid Stimulating Hormone (TSH) Test Kits as Compared to Third Generation TSH Test KitNo drug interventionsdiagnostic4completed
NCT00001159
Natural History of Thyroid Function DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT00206375
Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidismtreatment4terminated
NCT04747275
Use of Liquid Stable Levothyroxine in Trisomy 21 Pediatric Patientsother4terminated
NCT06083636
Improvement of Laboratory Diagnostics in Hypothyroid Patients Using LevothyroxineNo drug interventionsNot AvailableNot Availablerecruiting
NCT01358136
ThyrOp: A Study of Individual Subclinical Hypothyroidism After Hemithyroidectomy for Benign Nontoxic GoiterNo drug interventionsNot AvailableNot Availableunknown_status
NCT05143918
Quality of Life Among Egyptian Hypothyroid PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03988517
Comparing Two-time Points of Thyroid Hormone Replacement During the Holy Month of RamadanNo drug interventionstreatmentNot Availablecompleted
NCT05033496
The Yield of Postnatal Thyroid Function Test in the Well Baby NurseryNo drug interventionsNot AvailableNot Availablecompleted
NCT00818896
Maternal Hypothyroidism in PregnancyNo drug interventionsNot AvailableNot Availablecompleted
NCT00111735
Thyroxine Titration Studytreatment4unknown_status
NCT00001730
Study of Radioiodine (131-I) Uptake Following Administration of Thyrogen and Hypothyroid States During Thyroid Hormone Withdrawal.treatment4completed
NCT00205348
Swallowing Function Before and After Surgery for Thyroid GoiterNo drug interventionsNot AvailableNot Availablecompleted
NCT04831957
Hypothyroidism After the TAVI Procedure in Elderly PatientsNo drug interventionsdiagnosticNot Availablerecruiting
NCT01769157
Effects of L-carnitine on Hypothyroidismtreatment4completed
NCT01050465
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic UseNo drug interventionsNot AvailableNot Availablecompleted
NCT06015620
Comorbidities Resolution After MGB Surgery and Change in Body CompositionNo drug interventionsNot AvailableNot Availablerecruiting
NCT05247476
Type 2 Deiodinase Gene Polymorphism and the Treatment of Hypothyroidism Caused by Thyroidectomy in Thyroid Cancer Patients.treatment4unknown_status
NCT05070091
The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course.No drug interventionsNot AvailableNot Availablecompleted
NCT04098991
Improving White Matter Integrity With Thyroid HormoneNot AvailableNot Availablecompleted
NCT05385029
Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19Not AvailableNot Availablecompleted
NCT03180892
Non-immune Related Hypothyroidism in Iodine Sufficient AreaNo drug interventionsNot AvailableNot Availablecompleted
NCT00287144
Post Partum Thyroiditis 2: Long Term ObservationsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00488644
Combined Levothyroxine/Liothyronine Supplementation in Hypothyroid Patients With Brain TumorstreatmentNot Availableterminated
NCT02467244
Effect of Levothyroxine on Serum Adiponectin, Insulin Resistance and Cardiovascular Risk in Patients With HypothyroidismNot AvailableNot Availablecompleted
NCT01145040
NOMOTHETICOS: Nonlinear Modelling of Thyroid Hormones' Effect on Thyrotropin Incretion in Confirmed Open-loop SituationNo drug interventionsNot AvailableNot Availableunknown_status
NCT02577367
Mean Percentage of Levothyroxine Dosage Increase in Patients With Hypothyroidism Started on Enteral Feedingtreatment4withdrawn
NCT03342001
Hypothyroidism Treated With Calcitonintreatment4completed
NCT00715572
Combined Therapy With L-Thyroxine and L-Triiodothyronine Compared to L-Thyroxine AlonetreatmentNot Availablecompleted
NCT05421468
Timing of Thyroxine Dose In RamadanNo drug interventionstreatmentNot Availableunknown_status
NCT02891668
Hypothyroidism, Metabolism and Quality of Life - Focus on QOL, REE, Cognitive Function and Body CompositionNot AvailableNot Availablecompleted
NCT06179368
Throid Dysfunction in Liver Failure and Its Eddects Upon OutcomeNo drug interventionsNot AvailableNot Availablerecruiting
NCT04806269
Biosignals by Wearables in Thyroid DysfunctionNo drug interventionsNot AvailableNot Availablerecruiting
NCT01831869
Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidismtreatment4unknown_status
NCT01744769
Effects of Thyroid Hormone Withdrawal on Metabolic Parameters During Radioactive Iodine Therapy in Thyroid CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT05823012
Study of XP-8121 For the Treatment of Adult Subjects With Hypothyroidismtreatment2completed
NCT05821881
REduction of LEvothyroxine in Adults; a SElf Controlled StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06583395
Quest to Analyze One Thousand Humans MeditatingNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02190214
Thyroid Disorders in Malaysia: A Nationwide Multicentre StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04878614
Comparison of Levothyroxine Formulation in Hypothyroid Patients With Enteral Feedingtreatment4terminated
NCT02005250
Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and HypothyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT01105923
Study of an Intervention to Improve Problem List Accuracy and UseNo drug interventionsdiagnosticNot Availableunknown_status
NCT03612908
TSHβX1 and D2 THR92ALA in PregnancyNo drug interventionsNot AvailableNot Availablecompleted
NCT04784208
A Study to Determine the Validity and Sensitivity of 'Questionnaire to Screen for HYpothyroidism' (Q'SHY)No drug interventionsNot AvailableNot Availableunknown_status
NCT01744743
Preconceptional Thyroid Screening and Childhood Nerocognitive FunctionNo drug interventionspreventionNot Availableunknown_status
NCT06205303
Interventional Study to Improve Medication Adherence Using Patient Decision AidNo drug interventionssupportive_careNot Availablerecruiting
NCT05314790
Management of Patients With Diagnosis of Hypothyroidism, as Hospitalized and as Outpatients, in Internal Medicine Units: Observational Study Before & After Educational ProgrammeNo drug interventionsNot AvailableNot Availablecompleted
NCT00565864
Neurocognitive and Metabolic Effects of Mild Hypothyroidismtreatment4completed
NCT03754621
Upper Limit for TSH of First and Second Trimester Pregnancy in TurkeyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00230802
Thyroid Hormone Dose Adjustment in PregnancytreatmentNot Availablecompleted
NCT00336102
Thyroid Dysfunction in Women With Newly Diagnosed Breast Cancer Compared to Healthy VolunteersNo drug interventionsNot AvailableNot Availablecompleted
NCT02094079
Monitoring and Evaluation of the Levothyroxin Replacement Therapy in Pregnant Women With HypothyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT05412979
A Study Evaluating the Safety and Efficacy of Hormone Replacement Therapy With ST-1891 Compared to Levothyroxine in Patients With Primary Hypothyroidismtreatment2completed
NCT01801033
Effects of Thyroid Hormone Enzyme Blocking on HypothyroidismNo drug interventionsNot AvailableNot Availablewithdrawn
NCT06096454
Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistancetreatment4not_yet_recruiting
NCT05581147
Thyroid Function and Structure IN Klinefelter SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT04124705
A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participantstreatment2completed
NCT01197183
Observational Study With Prospective and/or Retrospective Follow-up, Without Modifying Patient Treatment and Follow-up Practices for the Initial Treatment of Hypothyroidism in FranceNo drug interventionsNot AvailableNot Availablecompleted
NCT02766283
Observational Study on Hypothyroidism in Young Children Following Iodine Contrast ExposureNo drug interventionsNot AvailableNot Availablecompleted
NCT05334771
Early Detection of Endolymphatic Hydrops in Hypothyroid PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02689609
Post-radiation Hypothyroidism After IMRT for Nasopharyngeal CarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01707056
The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid CarcinomaNo drug interventionstreatmentNot Availablewithdrawn
NCT03053115
Combined Replacement Therapy With Levothyroxine and Liothyronine in Thyroidectomized Patientstreatment2 / 3completed
NCT00094237
Subclinical Thyroid Dysfunction and Risk of Myocardial Infarction and StrokeNo drug interventionsNot AvailableNot Availablecompleted
NCT04236232
The Impact of Subclinical Hypothyroidism on Cardiovascular SystemNo drug interventionsNot AvailableNot Availableunknown_status
NCT06268600
The Protection of Thyroid Function in IMRT for Nasopharyngeal CarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT01204359
The Prospective Study of Standard Treatment of Graves Disease Iodine 131 and Prevention of Adverse ReactionsNo drug interventionsprevention3unknown_status
NCT03823859
Metabolomics of Thyroid HormonesNo drug interventionsNot AvailableNot Availablecompleted
NCT01379170
Thyroid Study Type 2 Diabetes Mellitus (T2DM)basic_science4unknown_status
NCT04332770
Biosignals by Wearable Devices in HypothyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT02710799
Evaluation of the Effects of Teleconsultations on a Endocrinology Referral ListNo drug interventionshealth_services_researchNot Availablecompleted
NCT03779906
Thyroid Function of Pediatric Subjects Following Isovue® Administrationother4active_not_recruiting
NCT01800617
A Study of T3 Therapy in Patients With Hypothyroidismtreatment2completed
NCT00770016
Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidismbasic_scienceNot Availableterminated
NCT03496363
Hypothyroidism With Congenital Heart Disease (CHD)No drug interventionsNot AvailableNot Availableunknown_status
NCT03095963
Interaction Between Levothyroxine and Probiotics in Hypothyroid PatientsotherNot Availablecompleted
NCT02917863
Randomized Crossover Trial for the Evaluation of the Possible Effects in the Intestine of Two Different Pharmaceutical Forms of L - Thyroxine in Patients With Primary Acquired HypothyroidismNot Available4unknown_status
NCT06345339
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participantstreatment2 / 3recruiting
NCT04860622
Normal Range of TSH and FT4 in PregnancyNo drug interventionsNot AvailableNot Availablecompleted
NCT04648722
Higher Levothyroxine Requirements After Right-side HemithyroidectomyNo drug interventionsNot AvailableNot Availablecompleted
NCT04528225
A Prospective Study of Hypothyroidism After Radiotherapy for Breast CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT05015725
The Relationship Between Serum rT3 Concentrations, T3/T4 Ratio, and Symptoms/Quality of Life in Treated Hypothyroid PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02280330
Iodine Status of Preschoolers Given Micronutrient Powder for 6 MonthsNo drug interventionssupportive_care4completed
NCT02317926
Desiccated Thyroid Extract Versus Synthetic T3/T4 Combination (ThyrolarTM) Versus L-T4 Alone in the Therapy of Primary Hypothyroidism With Special Attention to the Gene PolymorphismtreatmentNot Availableunknown_status
NCT03257566
Hypothyroidism in Patients With Type 1 DiabetesNo drug interventionsNot AvailableNot Availableunknown_status
NCT06566066
Register for Patients With Thyroid Hormone Resistance.No drug interventionsNot AvailableNot Availablerecruiting
NCT05975866
The Effects of an Anti-inflammatory Diet With or Without Curcumin Supplementation on Anthropometric Measurements, Concentrations of Thyroid Hormones, Anti-TPO, and Systemic Inflammation in Plasma and NFK-B in Peripheral Blood Mononuclear Cells in Patients With HashimatoNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT06073665
Dosing of LT4 in Older Individualstreatment4recruiting
NCT04877665
Establishing RIs for TSH in Children Under the Age of Two YearsNo drug interventionsNot AvailableNot Availablecompleted
NCT02301520
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.No drug interventionsNot AvailableNot Availablecompleted
NCT05760131
Awareness of Osteoporosis in Patients With HypothyroidismNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02959827
Iodinated Contrast Agents and Risk of Hypothyroidism in Young Children in the United StatesNo drug interventionsNot AvailableNot Availablecompleted
NCT03465176
The Effect of Aroma on Fatigue Scores Among Women With HypothyroidismNo drug interventionstreatmentNot Availablecompleted
NCT00747760
TSH Receptor Mutations Among a Consanguineous CommunityNo drug interventionsNot AvailableNot Availablecompleted
NCT02993562
Hypothyroidism, Metabolism and Food IntakeNot AvailableNot Availablecompleted
NCT04682340
Analysis of BPA Concentration in Serum in Women of Reproductive Age With Autoimmune Thyroid DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01916304
Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulationtreatment2completed
NCT01862510
Detection of Celiac Disease in Patients With HypothyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT01647750
Study of Optimal Replacement of Thyroxine in the Elderlytreatment4completed
NCT06452823
Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone StabilizationNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00524238
Metabolic Changes in Hypothyroid Patientsbasic_scienceNot Availablecompleted