Hematopoietic Subsyndrome of Acute Radiation Syndrome (DBCOND0020289)

Identifiers

Synonyms
Acute Radiation Syndrome / Hematopoietic Syndrome Due to Acute Radiation Syndrome / Hematopoietic subsyndrome of acute radiation syndrome / Acute radiation sickness / Acute radiation syndrome (disorder) / Hematopoietic subsyndrome of acute radiation syndrome (disorder) / Radiation sickness syndrome

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Filgrastim
A form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy.
Pegfilgrastim
A recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
Sargramostim
A modified form of recombinant human granulocyte-macrophage colony stimulating factor used to increase immune cell production after myelosuppressive therapy or bone marrow transplant.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02587442
A Study to Evaluate the Safety and Pharmacokinetics of RadProtect® in Healthy VolunteersNo drug interventionsprevention1unknown_status
NCT04650555
BIO 300 Oral Powder Safety and Pharmacokineticsprevention1completed
NCT03585803
A Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetic/Pharmacodynamic Characteristics of KMRC011No drug interventionstreatment1completed
NCT00504335
Safety and Pharmacokinetic Study of BIO 300 Capsulestreatment1completed
NCT00903929
Phase I Study of Eltrombopag for Promoting Thrombopoiesis After Total Body Irradiationtreatment1completed
NCT02343133
Safety Study of HemaMax™ (rHuIL-12) to Treat Acute Radiation Syndrometreatment2completed
NCT01742221
Safety and Tolerability of HemaMax™ (rHuIL-12) as Radiation Countermeasuretreatment1completed