Hyperkalemic Periodic Paralysis (DBCOND0037540)

Identifiers

Synonyms

Adynamia Episodica Hereditaria / Hyperkalemic periodic paralysis / Paralysis, Hyperkalemic Periodic / Periodic paralysis / Familial hyperkalemic periodic paralysis (disorder) / Hyperkalaemic periodic paralysis / Familial periodic paralysis / Familial periodic paralysis (disorder) / Paralysis periodic / Paralyses, Familial Periodic

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Diclofenamide	A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.	Carbonic anhydrase 1target Carbonic anhydrase 4target Carbonic anhydrase 2target Carbonic anhydrase 7target Carbonic anhydrase 3target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00494507	Hyper- and Hypokalemic Periodic Paralysis Study	Diclofenamide	treatment	3	completed
NCT00004802	Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders	Diclofenamide	treatment	3	completed
NCT01939561	Lamotrigine as Treatment of Myotonia	No drug interventions	treatment	3	completed