Severe Spasticity (DBCOND0042065)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Baclofen	A GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients.	Gamma-aminobutyric acid type B receptor subunit 1target Gamma-aminobutyric acid type B receptor subunit 2target C-X-C chemokine receptor type 4target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01520545	Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump	Baclofen	treatment	3	completed
NCT00773019	SynchroMed II Post-Approval Study	No drug interventions	Not Available	Not Available	completed
NCT01032239	SISTERS: Spasticity In Stroke Study - Randomized Study	Baclofen	treatment	4	completed