Advanced Solid Tumor Cancers (DBCOND0043086)

Identifiers

Synonyms

Advanced Solid Tumor Cancer / Advanced Solid Tumours / Advanced Solid Tumour / Solid Tumor in Advanced Stage / Advanced Stage Solid Tumors / Advanced Solid Tumor / Advanced Solid Tumors

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03821935	Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors	Budigalimab Livmoniplimab	treatment	1	recruiting
NCT06607939	ORB-021 In Patients With Advanced Solid Tumors	No drug interventions	treatment	1	not_yet_recruiting
NCT02955251	A Study of ABBV-428, an Immunotherapy, in Subjects With Advanced Solid Tumors	Nivolumab	treatment	1	completed
NCT03311477	A Study to Evaluate the Safety and Pharmacokinetics ABBV-399 in Japanese Participants With Solid Tumors	Telisotuzumab vedotin	treatment	1	completed
NCT03145909	A Study Evaluating the Safety, Pharmacokinetics and Anti-Tumor Activity of ABBV-176 in Subjects With Advanced Solid Tumors Likely to Express Prolactin Receptor (PRLR)	No drug interventions	treatment	1	terminated
NCT04721015	Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors	Docetaxel Osimertinib	treatment	1	active_not_recruiting
NCT04417465	First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors	No drug interventions	treatment	1	recruiting
NCT01208831	An East Asian Study of LDE225	Sonidegib	treatment	1	completed
NCT02988960	A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors	Budigalimab Giloralimab	treatment	1	active_not_recruiting
NCT00880308	Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors	Sonidegib	treatment	1	completed
NCT04196283	A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma	Budigalimab Paclitaxel Tilsotolimod	treatment	1	completed
NCT02099058	A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors	Erlotinib Nivolumab Osimertinib Telisotuzumab vedotin	treatment	1	active_not_recruiting
NCT05929235	A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma	No drug interventions	treatment	1	recruiting
NCT03071757	A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors	Budigalimab	treatment	1	completed
NCT03234712	A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)	No drug interventions	treatment	1	completed
NCT04777994	A Phase 1 Study With ABBV-CLS-484 in Subjects With Locally Advanced or Metastatic Tumors	Tyrosine	treatment	1	recruiting
NCT04389281	X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma	No drug interventions	treatment	1	recruiting
NCT00612209	A Phase 1 Study of ARQ 197 in Adult Patients With Advanced Solid Tumors	Tivantinib	treatment	1	completed
NCT06188975	Expanded Access to ABBV-CLS-484	No drug interventions	Not Available	Not Available	available
NCT00794131	Safety Study of GL-ONC1, an Oncolytic Virus, in Patients With Advanced Solid Tumors	Olvimulogene nanivacirepvec	treatment	1	completed
NCT01781455	A Study of BBI503 in Adult Patients With Advanced Solid Tumors	Amcasertib	treatment	1	completed