Chronic Venous Insufficiency (CVI) (DBCOND0052874)

Identifiers

Synonyms
Chronic Insufficiency Venous / Chronic Venous Insufficiency, CVI / Chronic Venous Insufficiency / Venous insufficiency (chronic) (peripheral) / Peripheral venous insufficiency (disorder) / Venous (peripheral) insufficiency, unspecified / Venous peripheral insufficiency / Venous insufficiency / Venous reflux disorder / Peripheral venous disease

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Hidrosmin
A synthetic bioflavonoid used for the short-term treatment of symptoms associated with chronic venous insufficiency.
No drug targets
Naftazone
A naphthoquinone derivative indicated in the treatment of varicose veins, hemorrhoids, and superficial thrombophlebitis.
No drug targets
Troxerutin
Troxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05005052
Sulodexide in the Treatment of Chronic Primary Venous Disease of the Lower Extremitiestreatment3recruiting
NCT06642051
Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the PeripheryNo drug interventionstreatmentNot Availablerecruiting
NCT04558957
Clinical Study to Assess the Safety and Efficacy of Mechanochemical Ablation With Flebogrif in Patients With Great Saphenous Vein InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT01402921
Efficacy on Volume Reduction and Tolerance of Progressiv' Medical Compressive Therapy (MCT) V0322 BC in Patients With Chronic Venous OedemaNo drug interventionstreatment3completed
NCT04225806
Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System - INFINITE-USNo drug interventionsdevice_feasibilityNot Availableterminated
NCT04757766
VAP-PRO-C6. Effectiveness and Tolerability of Venoactive Drugs in Combination Therapy in Patients With CVD (CEAP C6)No drug interventionsNot AvailableNot Availablecompleted
NCT05051540
The Effect of Inelastic Compression System on Quality of Life in People With Chronic Venous InsufficiencyNo drug interventionstreatmentNot Availablerecruiting
NCT02015221
Evaluation of a Dual Action Pneumatic Compression Device: Patient Ease of Use and ComfortNo drug interventionsNot AvailableNot Availablecompleted
NCT02395302
Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs)No drug interventionstreatmentNot Availablecompleted
NCT03904602
EdemaWear to Reduce Edema in Hospitalized Patients With CVI:No drug interventionspreventionNot Availableterminated
NCT03216005
Investigation of Femoropopliteal In Situ Valve Formation With the InterVene SystemNo drug interventionstreatmentNot Availablerecruiting
NCT02050061
Chronic Venous Insufficiency; Impact of Compression Stockings on Quality of LifeNo drug interventionssupportive_careNot Availablecompleted
NCT05662761
Assessment of the Relationship Between Severity of Chronic Venous Obstruction and Venous ClaudicationNo drug interventionsNot AvailableNot Availablerecruiting
NCT04339088
High Intensity Focused Ultrasound in PAtients With Varicose Veins in SingaporeNo drug interventionsNot AvailableNot Availableunknown_status
NCT01501188
Efficacy Study of Kinesio Taping to Treat Muscular and Joint Problems in Chronic Venous InsufficiencyNo drug interventionstreatment1completed
NCT04386785
Venclose RF Ablation System for the Treatment of IPVsNo drug interventionstreatmentNot Availablecompleted
NCT03104985
LLLT of Trophic Ulcers of Lower Extremities and Chronic Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT04384315
Efficacy and Safety of Endovenous Radio Frequency (EVRF) for Treatment of Varicose Veins in SingaporeNo drug interventionsNot AvailableNot Availableunknown_status
NCT03283800
Copper Impact on Venous Insufficiency and LipodermatosclerosisNo drug interventionssupportive_careNot Availablecompleted
NCT04339075
Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingAporeNo drug interventionsNot AvailableNot Availableunknown_status
NCT05504070
Venclose digiRF System Post Market StudyNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT06196541
Respiratory and Physical Functions in Individuals With Chronic Venous InsufficiencyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03900234
Prevalence of Chronic Venous Disease in General PopulationNo drug interventionsNot AvailableNot Availablecompleted
NCT01654016
Study of Antiinflammatory Effects of Detralex (Daflon)basic_science4completed
NCT02462096
A Feasibility Study of the ReLeaf Catheter SystemNo drug interventionstreatmentNot Availableterminated
NCT04897035
A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Dayspring Active Wearable Compression Technology for Treating Lower Extremity LymphedemaNo drug interventionstreatmentNot Availablecompleted
NCT05926830
Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal StudyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05625074
National Varicose Vein Study - PortugalNo drug interventionsNot AvailableNot Availablerecruiting
NCT01372020
Neuromuscular Electrical Therapy in Venous UlcersNo drug interventionstreatment4completed
NCT06418282
Clinical Study to Evaluate the Effectiveness and Health Economics of a Novel Portable Non-Pneumatic Active Compression Device (NPCD) for Lymphedema/PhlebolymphedemaNo drug interventionstreatmentNot Availablerecruiting
NCT02559427
SPA Therapy in the Treatment of Sleep Apnea SyndromeNo drug interventionstreatmentNot Availablewithdrawn
NCT04580160
Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent SystemNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05058989
The Evaluation of the Pathophysiology of Varicose Veins in PregnancyNo drug interventionsNot AvailableNot Availablecompleted
NCT02248740
Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous VeinNo drug interventionstreatment4terminated
NCT04253301
Feasibility of the InnoVein Valve and Delivery System for Chronic Venous InsufficiencyNo drug interventionstreatmentNot Availablerecruiting
NCT05507346
A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity LymphedemaNo drug interventionstreatmentNot Availablecompleted
NCT04424095
Venous Disease in Pediatric PopulationNo drug interventionsNot AvailableNot Availableunknown_status
NCT03384355
Ecchymosis and Coldness in Patients With Varicose VeinNo drug interventionsNot AvailableNot Availableunknown_status
NCT05993650
Inspiratory Muscle Training in Chronic Venous DiseasesNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT03685838
Compression Stockings Therapy Following Mechano-Chemical Ablation (Clarivein®)No drug interventionstreatmentNot Availableunknown_status
NCT05449743
Assessment of the Effect of Spa Therapy on the Quality of Life of Patients With Chronic Venous Insufficiency (NEYRAC)No drug interventionstreatmentNot Availableunknown_status
NCT06232421
Clinical Study in Adult Patients With Purulent-inflammatory Processes of the Skin and Soft Tissues, Phase I-II of the Wound Processtreatment2 / 3not_yet_recruiting
NCT05047302
Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System-CanadaNo drug interventionstreatmentNot Availablewithdrawn
NCT04236245
EU Post Market Clinical Follow-Up Study of the Venclose System for Saphenous Vein IncompetenceNo drug interventionstreatmentNot Availablecompleted
NCT05982405
Long-term Effects of Inspiratory Muscle Training in Chronic Venous InsufficiencyNo drug interventionssupportive_careNot Availablerecruiting
NCT02927483
Study to Assess the Efficacy and Safety of Endolex Forte VErsus Diosmin and Hesperidin in Reducing VeNous InsufficiencyNo drug interventionstreatment3unknown_status
NCT01574911
Validation of a New Method of Limb VolumetryNo drug interventionsNot AvailableNot Availableunknown_status
NCT05749471
Sex Dysfunction and Chronic Venous DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT05628688
A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)No drug interventionsNot AvailableNot Availablerecruiting
NCT01000909
Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose VeinsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05622500
Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT03835559
Cyanoacrylate Closure Versus Surgical Stripping for Incompetent Saphenous VeinsNo drug interventionstreatmentNot Availableunknown_status
NCT04231942
Elastic Compression Stockings and Varicose Veins RecurrenceNo drug interventionstreatmentNot Availablerecruiting
NCT01321619
Efficacy and Tolerability of the Use of Varicell Compared With Daflontreatment3unknown_status
NCT02346058
Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose VeinsNo drug interventionstreatment4completed
NCT06579482
Clinical Trial of Aesculus Hippocastanum and Associations Versus Diosmina and Hesperidina in Chronic Venous InsuficiencyNo drug interventionstreatment4recruiting
NCT01899482
Manual Lymphatic Drainage in Chronic Venous Insufficiency: a Randomized Controlled TrialNo drug interventionssupportive_careNot Availablecompleted
NCT03784131
Tissue Engineered Veins in Patients With Chronic Venous InsufficiencyNo drug interventionstreatment1recruiting
NCT02662127
Effect of Standing, Lying and Stockings on Blood Bio-markers (v.1)No drug interventionsbasic_scienceNot Availableunknown_status
NCT06238791
Plantar Pressure Analysis and Foot Biomechanics in Lipedema and Chronic Venous DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03445091
Study to Evaluate Impact SANKOM Patent Socks in Patients With CVINo drug interventionssupportive_careNot Availableunknown_status
NCT04054440
Outpatient Office Based Endovascular ProceduresNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03893201
A Singapore Venaseal Real World Post-Market Evaluation StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02215369
SeCure Endovenous Laser Treatment StudyNo drug interventionstreatmentNot Availablecompleted
NCT05383469
Efficacy of Active Versus Passive Methods in Chronic Venous InsufficiencyNo drug interventionstreatmentNot Availablecompleted
NCT03562546
The Effect of Structured Exercise on Chronic Venous InsufficiencyNo drug interventionstreatmentNot Availableunknown_status
NCT06175546
Daily Duration of Compression Treatment in Patients With Symptomatic Chronic Venous DiseaseNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT04794712
Evaluation of Pain Associated With Chronic Venous InsufficiencyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01848210
Efficacy and Safety of Coumarin and Troxerutin in the Symptomatic Treatment of Chronic Venous Insufficiencytreatment4completed
NCT01477281
Study to Evaluate the Efficacy and Tolerability of Venaflon Use in Reducing the Symptoms Caused by Chronic Venous Insufficiency When Compared With Daflontreatment3unknown_status
NCT01432795
Practicability of Gliding Aids for Medical Compression StockingsNo drug interventionstreatment4completed
NCT02236338
Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous VeinNo drug interventionstreatment4completed