Second Degree Burns (DBCOND0057796)

Identifiers

Synonyms

Burns second degree / Burn Second Degree / Second Degree Burn / Second-degree Burn / 2nd degree Burn / Burns Degree Second / Burn Degree Second / Second degree burns / Blisters with epidermal loss due to burn (second degree), unspecified site / Second degree burn injury (morphologic abnormality) / Partial thickness burn (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Centella asiatica	Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.	No drug targets
Mafenide	An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.	Carbonic anhydrase 6target Carbonic anhydrase 2target Carbonic anhydrase 12target Carbonic anhydrase 14target Carbonic anhydrase 4target
Nepidermin	Not Annotated	No drug targets
Silver sulfadiazine	A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.	DNAtarget Dihydropteroate synthasetarget
Sulfadiazine	A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.	Cytochrome P450 2C9enzyme Dihydropteroate synthetasetarget Cytochrome P450 2C8enzyme Cytochrome P450 3A4enzyme Dihydropteroate synthasetarget
Zinc oxide	A mineral ingredient of various pharmacological preparations to treat diaper dermatitis and other skin conditions, to protect the epidermis, and to prevent sunburn.	No drug targets

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04890574	CellMist™ Autologous Cells to Treat Deep Second-Degree Burns	No drug interventions	treatment	1	unknown_status
NCT03702972	Thermal Imaging and Pediatric Burns	No drug interventions	Not Available	Not Available	unknown_status
NCT04412759	PORCINE XENOGRAFT OR MICROBIAL CELLULOSE IN THE TREATMENT OF PARTIAL THICKNESS BURNS	No drug interventions	treatment	Not Available	completed
NCT06263296	Smartphone Assisted Self-management Education for Adult Burn Patient at Aftercare	No drug interventions	treatment	Not Available	recruiting
NCT06596434	4-Aminopyridine to Treat Skin Burns	Dalfampridine	treatment	2	not_yet_recruiting
NCT03048188	Manuka Honey in Second- and Grafted Third-degree Burns	No drug interventions	treatment	Not Available	recruiting
NCT02108535	Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns	Silver Silver sulfadiazine	treatment	4	completed
NCT00742183	Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®	No drug interventions	health_services_research	Not Available	completed
NCT03530150	Pirfenidone and Its Role in Burn Wound Healing	Pirfenidone	treatment	2	completed
NCT04684121	Study of the Efficacy and Safety of Granexin® Gel to Improve Burn Wound Healing	ACT-1 peptide	treatment	2	withdrawn
NCT01055587	Diagnostic of Infections Following Major Abdominal Surgery and Burn Injury	No drug interventions	Not Available	Not Available	completed
NCT04149808	Mepilex Ag vs. Xeroform in Pediatric Patients That Sustain Partial Thickness Burn Injury	No drug interventions	treatment	Not Available	withdrawn
NCT05347654	Evaluation of a Management Strategy for Second-degree Fibrinous Burns Integrating a Poly-absorbent Dressing	No drug interventions	treatment	Not Available	recruiting
NCT04276818	Use of Platelet-rich Plasma in Second-degree Superficial Burns	No drug interventions	treatment	Not Available	completed
NCT02497326	Heparin for the Treatment of Burn Wound Pain	Chlorhexidine Heparin Polymyxin B Silver sulfadiazine Tramadol	treatment	Not Available	unknown_status
NCT01627769	Evaluation and Comparison of Keloids and Second Degree Burns Blisters Fluid	No drug interventions	Not Available	Not Available	unknown_status
NCT04200053	The Effect of Reflexology Massage and Passive Music Therapy Intervention Before Burn Dressing	No drug interventions	supportive_care	Not Available	completed
NCT04685577	Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients	Nefopam	prevention	2	recruiting
NCT05612867	Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C	No drug interventions	Not Available	Not Available	completed
NCT05652816	Biological Skin Graft With Keratinocyte-stem Cell Co-cultre for Burn Patients	No drug interventions	treatment	0	recruiting
NCT06440239	A Study to Evaluate the Safety, Tolerability and Efficacy in Patients With Burn(s)	No drug interventions	treatment	1 / 2	not_yet_recruiting
NCT04772573	The Treatment Challenges and Limitation in High-Voltage Pediatric Electrical Burn at Rural Area	No drug interventions	Not Available	Not Available	completed
NCT06223269	Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting	No drug interventions	treatment	3	recruiting