Chronic Traumatic Encephalopathy (CTE) (DBCOND0064690)

Identifiers

Synonyms

CTE - Chronic Traumatic Encephalopathy / Traumatic Encephalopathies, Chronic / Traumatic Encephalopathy, Chronic / Traumatic Chronic Encephalopathy / Chronic Traumatic Encephalopathy / Chronic traumatic encephalopathy (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Flortaucipir F-18	A small lipophilic tracer containing [18F]fluoride capable of crossing the blood-brain barrier and binding to aggregated tau protein; used in PET imaging for the diagnosis of Alzheimer's disease.	Microtubule-associated protein tautarget Amine oxidase [flavin-containing] Atarget Amine oxidase [flavin-containing] Btarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06147596	Heading in Football: Impact on Neural Blood Biomarkers	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT02959294	Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries	No drug interventions	treatment	0	withdrawn
NCT04928534	Cohort Study of Blood Biomarkers for TES	No drug interventions	Not Available	Not Available	recruiting
NCT04903015	Cerebral and Cognitive Impact of Professional Soccer Practice	No drug interventions	screening	Not Available	recruiting
NCT01891383	Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel	No drug interventions	Not Available	Not Available	withdrawn
NCT04796207	The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes	No drug interventions	prevention	Not Available	completed
NCT02103894	Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects	Florbetapir F-18	Not Available	1	completed
NCT03944447	Outcomes Mandate National Integration With Cannabis as Medicine	Medical Cannabis	treatment	2	recruiting
NCT02795052	Neurologic Stem Cell Treatment Study	No drug interventions	treatment	Not Available	recruiting
NCT02079766	18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy	Florbetapir F-18 Flortaucipir F-18	diagnostic	2	completed
NCT05490576	Tau And Connectomics In TES Study	No drug interventions	diagnostic	1	active_not_recruiting
NCT06254469	Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease	No drug interventions	diagnostic	3	not_yet_recruiting
NCT05235802	Long-term Follow-up in Severe Traumatic Brain Injury	No drug interventions	Not Available	Not Available	recruiting
NCT02798185	The DIAGNOSE-CTE Research Project	No drug interventions	Not Available	Not Available	completed
NCT03218332	Post-Concussion Syndrome in Professional Athletes: A Multidisciplinary Study	No drug interventions	Not Available	Not Available	recruiting
NCT03724136	Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study	No drug interventions	treatment	Not Available	enrolling_by_invitation
NCT02266563	Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury	Florbetapir F-18	Not Available	Not Available	completed
NCT04489082	Near-Infrared Laser Stimulation for Various Neurological Conditions	No drug interventions	treatment	Not Available	enrolling_by_invitation
NCT02191267	Tau Imaging of Chronic Traumatic Encephalopathy	No drug interventions	diagnostic	2	completed