Primary Progressive Aphasia(PPA) (DBCOND0136327)

Identifiers

Synonyms

Aphasia, Primary Progressive / Aphasia Primary Progressive / Primary Aphasia, Progressive / Progressive Primary Aphasia / Primary Progressive Aphasia / Pick's disease / Primary progressive apraxia of speech (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06473714	Effects of Transcranial Direct Current Stimulation (tDCS) on Inhibition and Brain Function in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	recruiting
NCT05437159	Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech	No drug interventions	basic_science	Not Available	recruiting
NCT02675270	Rehabilitation and Prophylaxis of Anomia in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	active_not_recruiting
NCT06066710	Propranolol in Primary Progressive Aphasia	Propranolol	treatment	0	recruiting
NCT03448133	rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Trial	No drug interventions	treatment	Not Available	withdrawn
NCT04937452	Dopaminergic Therapy for Frontotemporal Dementia Patients	Rotigotine	treatment	2	unknown_status
NCT04623125	Spaced Retrieval as Treatment for Aphasia	No drug interventions	treatment	Not Available	completed
NCT02297035	Characterisation of Primary Progressives Aphasias	No drug interventions	diagnostic	Not Available	unknown_status
NCT02873546	tDCS Effect on Cognitive Functions From Patients With Alzheimer's Disease or Progressive Primary Aphasia	No drug interventions	treatment	Not Available	unknown_status
NCT05697380	CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia)	No drug interventions	treatment	Not Available	completed
NCT05901233	Speech-Language Treatment with Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	active_not_recruiting
NCT06191198	Communication Bridge 3 Study	No drug interventions	treatment	2	recruiting
NCT06211374	Communication Bridge Pilot Study	No drug interventions	treatment	Not Available	active_not_recruiting
NCT06649084	Primary Progressive Aphasia Multicomponent Language Treatment Study	No drug interventions	treatment	Not Available	active_not_recruiting
NCT04187391	The Effects of a Multimodal Approach for the Treatment of PPA	No drug interventions	treatment	Not Available	completed
NCT04290988	Circuitry Assessment and Reinforcement Training Effects on Recovery	No drug interventions	treatment	Not Available	suspended
NCT04726527	Clinical Evaluation of Florbetapir in Primary Progressive Aphasia	Florbetapir F-18	Not Available	Not Available	completed
NCT05386394	Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia	No drug interventions	treatment	2	recruiting
NCT05615922	Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA)	No drug interventions	treatment	2	completed
NCT05730023	A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:3430931	No drug interventions	treatment	Not Available	recruiting
NCT04045990	Network Modulation in Alzheimer's Disease	No drug interventions	treatment	Not Available	completed
NCT01623284	PiB PET Scanning in Speech and Language Based Dementias	Pittsburgh Compound B	diagnostic	1	completed
NCT05443633	Enhancing Language Function in Aphasia	No drug interventions	treatment	Not Available	recruiting
NCT02439853	Communication Bridge Speech Therapy Research Study	No drug interventions	supportive_care	Not Available	completed
NCT05741853	Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia	No drug interventions	treatment	Not Available	recruiting
NCT05525377	Better Living With Non-memory-led Dementia	No drug interventions	treatment	Not Available	completed
NCT05860647	Transmagnetic Stimulation Pilot in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	completed
NCT05742698	Nabilone for Agitation in Frontotemporal Dementia	Nabilone	treatment	2	active_not_recruiting
NCT02541097	Preventing Language Decline in Dementia	No drug interventions	prevention	Not Available	completed
NCT03313011	The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech	No drug interventions	Not Available	Not Available	recruiting
NCT03076671	More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease	No drug interventions	treatment	Not Available	completed
NCT03153371	Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks	No drug interventions	Not Available	Not Available	unknown_status
NCT06511752	Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia	No drug interventions	treatment	0	recruiting
NCT03805659	HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms	No drug interventions	treatment	Not Available	completed
NCT04486586	Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia	No drug interventions	treatment	Not Available	active_not_recruiting
NCT02606422	tDCS Intervention in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	completed
NCT03728582	Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy	No drug interventions	treatment	Not Available	completed
NCT04046991	Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS	No drug interventions	treatment	2	recruiting
NCT06529744	Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling	No drug interventions	Not Available	Not Available	recruiting
NCT05978804	Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease	No drug interventions	treatment	Not Available	enrolling_by_invitation
NCT00537004	Language in Primary Progressive Aphasia	No drug interventions	Not Available	Not Available	recruiting
NCT00957710	Language Treatment for Progressive Aphasia	No drug interventions	Not Available	Not Available	completed
NCT05368350	Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation	No drug interventions	treatment	0	enrolling_by_invitation
NCT03580954	Transcranial Magnetic Stimulation in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	completed
NCT04412083	PPA Tele-Savvy: A Pilot Study of an Online Intervention for Caregivers of Persons Living With PPA	No drug interventions	supportive_care	Not Available	completed
NCT01818661	Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech	No drug interventions	diagnostic	4	recruiting
NCT05537688	Identification of Graphic Markers of Neurocognitive Disorders (MG)	No drug interventions	Not Available	Not Available	completed
NCT04957537	Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia	No drug interventions	treatment	Not Available	recruiting
NCT06181500	Home-Based Exercise in Primary Progressive Aphasia (HEPPA)	No drug interventions	supportive_care	Not Available	active_not_recruiting
NCT03371706	Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia	No drug interventions	treatment	Not Available	completed
NCT04920318	Enhancing Language Function in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	recruiting
NCT04939818	Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders	No drug interventions	Not Available	Not Available	completed
NCT04881617	Treatment for Speech and Language in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	active_not_recruiting
NCT02928848	Transcranial Direct Current Stimulation for Primary Progressive Aphasia	No drug interventions	treatment	Not Available	completed
NCT04566731	Treating Primary Progressive Aphasia (PPA) Using tDCS	No drug interventions	treatment	Not Available	recruiting
NCT05842473	Long-term Effect of TMS in Primary Progressive Aphasia	No drug interventions	treatment	Not Available	active_not_recruiting
NCT01465360	Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center	No drug interventions	Not Available	Not Available	completed
NCT04431401	rTMS Treatment of Primary Progressive Aphasia	No drug interventions	treatment	Not Available	completed
NCT04720001	Florbetaben PET Imaging in PPA	Florbetaben F-18	Not Available	Not Available	completed
NCT03887481	Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA	No drug interventions	treatment	Not Available	recruiting
NCT02736695	Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia	No drug interventions	diagnostic	Not Available	recruiting
NCT06613204	STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners	No drug interventions	supportive_care	Not Available	not_yet_recruiting
NCT04715399	UPenn Observational Research Repository on Neurodegenerative Disease	No drug interventions	Not Available	Not Available	recruiting