Peroxisome proliferator-activated receptor alpha

BE0000071ProteinHumansPPARA

Ligand-activated transcription factor. It is acted on by 75 drugs in DrugBank.

Gene name
PPARA
UniProtKB entry
Q07869Swiss-Prot
Cellular location
Nucleus
Residues / weight
468 residues · 52,225 Da
Also known as
NR1C1 · Nuclear receptor subfamily 1 group C member 1 · PPAR · PPAR-alpha

Resolves to

Protein
UniProtQ07869UniProt namePPARA_HUMAN
Gene
HGNCHGNC:9232NCBI Gene5465GenBank307341GeneCardsPPARA
Pharmacology
IUPHAR/GtoPdb593KEGGhsa:5465
Structure
PDB1I7GPDB1K7LPDB1KKQ
Drugs

What you can answer from here — as of September 07, 2019

75DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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46GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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235+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peroxisome proliferator-activated receptor alpha, how selective are they, and which programs against it are still in active trials?

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