- Azabicyclo Compounds
- Accession Number
Bicyclic bridged compounds that contain a nitrogen which has three bonds. The nomenclature indicates the number of atoms in each path around the rings, such as [2.2.2] for three equal length paths. Some members are TROPANES and BETA LACTAMS.
Drug Drug Description Trospium An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). Ipratropium An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD). Phenoxymethylpenicillin A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. Hyoscyamine An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. Anisotropine methylbromide For use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying. Cefdinir A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Cephalexin A first generation cephalosporin used to treat certain susceptible bacterial infections. Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. Homatropine methylbromide A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. Scopolamine A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV). Biperiden A muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs. Granisetron A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. Cocaine An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. Tiotropium A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Benzoylecgonine Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after... Ecgonine Not Available Tazobactam A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. Tropinone Not Available Pseudotropine Not Available Methylecgonine Not Available Altropane Investigated for use/treatment in attention deficit/hyperactivity disorder (ADHD), parkinson's disease, and pediatric indications. NS-2359 Investigated for use/treatment in addictions, attention deficit/hyperactivity disorder (ADHD), and depression. Ioflupane I-123 A radiopharmaceutical used in single photon emission computed tomography (SPECT) brain imaging to help diagnose patients with suspected Parkinsonian syndromes. Aclidinium An inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD). Fentonium Fentonium is an atropine derivative. Cimetropium Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which... Butylscopolamine An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. Homatropine An anticholinergic agent used to dilate the pupil, treat inflammation of the uveal tract, and suppress a cough. Methscopolamine Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... Axelopran Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation. Oxitropium Oxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive. Etybenzatropine Not Annotated Methylatropine Not Annotated Ceftolozane A cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia. Deptropine Not Annotated Butropium A medication indicated to treat pain caused by gastrointestinal inflammation and ulcers, or diseases of the gallbladder. Calystegine B2 Not Available
- Drugs & Drug Targets