Pyrimidines

DBCAT000349Pharmacologic class

A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates. A DrugBank category of 249 drugs. 81 of them are approved.

Drugs: 1-Methylcytosine
2'-C-methylcytidine
2'-cytidylic acid
2'-Deoxy-thymidine-beta-L-rhamnose
2'-Deoxycytidine 5'-triphosphate
2'-Deoxyuridine
2'-fluoro-5-ethylarabinosyluracil
3-Deazacytidine
3-Methylcytosine
3'-Uridinemonophosphate
5-Aminouracil
5-Benzylacyclouridine
5-fluoro-2'-deoxycytidine
5-fluoro-2'-deoxyuridine-5'-monophosphate
5-fluorouridine
5-Iodouracil
5-methylcytidine 5'-monophosphate
5-Methyluridine triphosphate
5,6-Diaminouracil
5,6-dihydro-5-azacytidine
6-aza uridine 5'-monophosphate
ABT-072
Adafosbuvir
Adavosertib
Aditoprim
and 224 more with a free account

What you can answer from here — as of August 24, 2016

249DrugsEach linked to its full drug card

342Drug targetsEvery drug–target pair in the class, with bond type

17,942Marketed productsAcross the regions we cover, with dosage forms and routes

23Routes of administrationHow the drugs in this class are given

Which targets do Pyrimidines share, and which companies have late-stage candidates in this class?

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