Impaired Renal Function

Also known as: Deteriorating renal function / Impairment of renal function / Decreased renal function / Renal Impairments / Impairment in renal function / Renal Function Impairment / Renal Impairment / Renal Impaired / Renal Insufficiency / Impaired kidney function / Kidney Insufficiency / Kidney impairment / Decline in Renal Function / Renal insufficiency (disorder) / Insufficiency renal / Renal impairment (disorder) / Renal impairment NOS / Kidney Failure / Renal failure / (Renal failure NOS) or (uraemia NOS) / Renal failure syndrome (disorder) / Failure kidney / Uremia NOS / Renal failure, unspecified / Renal failure unspecified (disorder) / Renal failure NOS / Renal failure unspecified / (Renal failure unspecified) or (uraemia NOS)

Drugs
Drug Trials

Drug	Drug Name	Drug Description
DB11126	Calcium gluconate	An ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning.
DB08898	Glucarpidase	A carboxypeptidase enzyme used to reduce plasma concentrations of methotrexate in patients with impaired renal function.

Drug	Drug Name	Target	Type

Drug	Drug Name	Phase	Status	Count
DB16451	AT-527	1	Recruiting	1
DB11804	AZD-5672	1	Completed	1
DB15418	AZD-9977	1	Completed	1
DB05812	Abiraterone	1	Completed	1
DB14973	Abrocitinib	1	Completed	1
DB14906	Adafosbuvir	1	Completed	1
DB08916	Afatinib	1	Completed	1
DB06594	Agomelatine	1	Completed	1
DB16086	Aldafermin	1	Completed	1
DB12597	Asciminib	1	Completed	1
DB01076	Atorvastatin	1	Completed	1
DB14857	Avadomide	1	Completed	1
DB16354	Avasopasem manganese	1	Completed	1
DB09060	Avibactam	1	Completed	1
DB00928	Azacitidine	1	Completed	1
DB00355	Aztreonam	1	Completed	1
DB06681	Belatacept	1	Completed	1
DB15463	Belzutifan	1	Recruiting	1
DB09258	Bemiparin	1	Completed	1
DB05229	Beraprost	1	Completed	1
DB12364	Betrixaban	1	Completed	1
DB12464	Bevenopran	1	Terminated	1
DB16906	Bocidelpar	1	Completed	1
DB15638	Brensocatib	1	Completed	1
DB11666	Buparlisib	1	Completed	1
DB05153	Cabozantinib	1	Completed	1
DB08875	Cabozantinib	1	Completed	1
DB08907	Canagliflozin	1	Completed	1
DB09061	Cannabidiol	1	Withdrawn	1
DB00958	Carboplatin	1	Completed	1
DB01413	Cefepime	1	Completed	2
DB11777	Cenderitide	1	Withdrawn	1
DB12705	Cenerimod	1	Recruiting	1
DB01432	Cholestyramine	1	Completed	1
DB11890	Cilengitide	1	Completed	1
DB00515	Cisplatin	1	Completed	1
DB15194	Cotadutide	1	Completed	1
DB08865	Crizotinib	1	Completed	1
DB00531	Cyclophosphamide	1	Completed	1
DB09028	Cytisine	1	Recruiting	1
DB01914	D-glucose	1	Withdrawn	1
DB14726	Dabigatran	1	Completed	1
DB06695	Dabigatran etexilate	1	Completed	1
DB08912	Dabrafenib	1	Completed	1
DB06637	Dalfampridine	1	Completed	1
DB15031	Daridorexant	1	Completed	1
DB12941	Darolutamide	1	Completed	1
DB13120	Deferitazole	1	Completed	1
DB11921	Deflazacort	1	Completed	1
DB14850	Deleobuvir	1	Terminated	1
DB06643	Denosumab	1	Completed	1
DB16650	Deucravacitinib	1	Completed	1
DB01234	Dexamethasone	1	Completed	1
DB11807	Dexmecamylamine	1	Completed	1
DB15130	Dexpramipexole	1	Completed	1
DB01248	Docetaxel	1	Completed	1
DB12301	Doravirine	1	Completed	1
DB16145	Dotinurad	1	Completed	1
DB00470	Dronabinol	1	Withdrawn	1
DB15080	ELX-02	1	Completed	1
DB12243	Edaravone	1	Completed	1
DB05187	Elafibranor	1	Completed	1
DB11574	Elbasvir	1	Completed	1
DB06350	Elinogrel	1	Terminated	1
DB05408	Emricasan	1	Completed	1
DB11726	Encenicline	1	Completed	1
DB11841	Entinostat	1	Completed	1
DB11744	Epetraborole	1	Completed	1
DB11827	Ertugliflozin	1	Completed	1
DB00199	Erythromycin	1	Completed	1
DB11823	Esketamine	1	Completed	1
DB15170	Evobrutinib	1	Completed	1
DB12625	Evogliptin	1	Completed	1
DB01276	Exenatide	1	Completed	1
DB11808	Faldaprevir	1	Terminated	1
DB12500	Fedratinib	1	Completed	1
DB12725	Felcisetrag	1	Completed	1
DB12011	Fevipiprant	1	Completed	1
DB15669	Fezolinetant	1	Completed	1
DB09279	Fimasartan	1	Completed	1
DB08868	Fingolimod	1	Completed	1
DB15637	Fluzoparib	1	Not Yet Recruiting	1
DB00569	Fondaparinux	1	Completed	1
DB12010	Fostamatinib	1	Completed	1
DB11679	Fruquintinib	1	Recruiting	1
DB00695	Furosemide	1	Terminated	1
DB17084	Gadopiclenol	1	Completed	1
DB15097	Gefapixant	1	Completed	1
DB12141	Gilteritinib	1	Completed	1
DB11978	Glasdegib	1	Completed	1
DB13879	Glecaprevir	1	Completed	1
DB14794	Glepaglutide	1	Completed	1
DB06583	Glycopyrronium	1	Completed	1
DB11575	Grazoprevir	1	Completed	1
DB00956	Hydrocodone	1	Completed	2
DB12101	Iberdomide	1	Completed	1
DB12105	Imagabalin	1	Terminated	1
DB14901	Inclisiran	1	Completed	1
DB01362	Iohexol	1	Withdrawn	1
DB11633	Isavuconazole	1	Completed	1
DB06636	Isavuconazonium	1	Completed	1
DB06218	Lacosamide	1	Completed	1
DB14814	Lanabecestat	1	Withdrawn	1
DB11951	Lemborexant	1	Completed	1
DB09078	Lenvatinib	1	Completed	1
DB08882	Linagliptin	1	Completed	1
DB17083	Linzagolix	1	Completed	1
DB09198	Lobeglitazone	1	Completed	1
DB04871	Lorcaserin	1	Completed	1
DB12130	Lorlatinib	1	Completed	1
DB14808	Lumicitabine	1	Completed	1
DB11968	MK-7145	1	Terminated	1
DB11968	MK-7145	1	Withdrawn	1
DB06800	Methylnaltrexone	1	Completed	1
DB00683	Midazolam	1	Completed	1
DB16233	Milvexian	1	Completed	1
DB08893	Mirabegron	1	Completed	1
DB11792	Mirodenafil	1	Completed	1
DB16390	Mobocertinib	1	Completed	1
DB15661	Molnupiravir	1	Completed	1
DB14777	Murepavadin	1	Completed	1
DB14011	Nabiximols	1	Withdrawn	1
DB15353	Nacubactam	1	Completed	1
DB06230	Nalmefene	1	Completed	1
DB09049	Naloxegol	1	Completed	1
DB00238	Nevirapine	1	Completed	1
DB16691	Nirmatrelvir	1	Completed	1
DB00507	Nitazoxanide	1	Completed	1
DB13041	Odalasvir	1	Completed	1
DB06670	Odanacatib	1	Completed	1
DB15245	Olorofim	1	Completed	1
DB11837	Osilodrostat	1	Completed	1
DB06635	Otamixaban	1	Completed	1
DB14955	PF-04634817	1	Completed	1
DB14924	PF-06651600	1	Terminated	1
DB15003	PF-06700841	1	Completed	1
DB16043	PF-06882961	1	Completed	1
DB01229	Paclitaxel	1	Completed	2
DB09073	Palbociclib	1	Completed	1
DB01267	Paliperidone	1	Completed	1
DB06663	Pasireotide	1	Completed	1
DB16279	Pecavaptan	1	Completed	1
DB00022	Peginterferon alfa-2b	1	Completed	1
DB09122	Peginterferon beta-1a	1	Completed	1
DB11759	Pevonedistat	1	Completed	1
DB00191	Phentermine	1	Completed	1
DB13878	Pibrentasvir	1	Completed	1
DB04951	Pirfenidone	1	Recruiting	1
DB08860	Pitavastatin	1	Completed	1
DB11642	Pitolisant	1	Completed	1
DB12615	Plazomicin	1	Completed	1
DB06809	Plerixafor	1	Completed	1
DB11333	Poloxamer 188	1	Completed	1
DB08910	Pomalidomide	1	Completed	1
DB05154	Pretomanid	1	Suspended	1
DB01032	Probenecid	1	Recruiting	1
DB00468	Quinine	1	Terminated	1
DB12935	Remogliflozin etabonate	1	Completed	1
DB14898	Retagliptin	1	Completed	1
DB11855	Revefenacin	1	Completed	1
DB11730	Ribociclib	1	Completed	1
DB00615	Rifabutin	1	Completed	1
DB01045	Rifampicin	1	Completed	1
DB00503	Ritonavir	1	Completed	1
DB00073	Rituximab	1	Completed	2
DB06228	Rivaroxaban	1	Completed	1
DB12544	Rivipansel	1	Completed	1
DB12778	Rivipansel	1	Completed	1
DB01098	Rosuvastatin	1	Completed	1
DB04847	Roxadustat	1	Completed	2
DB06654	Safinamide	1	Completed	1
DB15685	Selpercatinib	1	Completed	1
DB14961	Seltorexant	1	Completed	1
DB13928	Semaglutide	1	Completed	1
DB11700	Setmelanotide	1	Completed	1
DB12371	Siponimod	1	Completed	1
DB01261	Sitagliptin	1	Completed	1
DB11159	Sodium sulfide	1	Terminated	1
DB12713	Sotagliflozin	1	Completed	2
DB06206	Sugammadex	1	Completed	1
DB15106	Surufatinib	1	Completed	1
DB00864	Tacrolimus	1	Completed	1
DB05359	Tasimelteon	1	Completed	1
DB09071	Tasimelteon	1	Completed	1
DB14899	Tavapadon	1	Recruiting	1
DB01606	Tazobactam	1	Completed	1
DB14569	Tedizolid	1	Completed	1
DB08900	Teduglutide	1	Completed	1
DB12095	Telotristat ethyl	1	Completed	1
DB14925	Tenofovir exalidex	1	Completed	1
DB08880	Teriflunomide	1	Completed	1
DB04902	Ticagrelor	1	Completed	1
DB08816	Ticagrelor	1	Completed	1
DB01409	Tiotropium	1	Completed	1
DB00775	Tirofiban	1	Completed	1
DB15171	Tirzepatide	1	Completed	1
DB08895	Tofacitinib	1	Completed	1
DB00214	Torasemide	1	Terminated	1
DB12056	Trebananib	1	Completed	1
DB06267	Udenafil	1	Completed	1
DB12164	Varespladib methyl	1	Terminated	1
DB11581	Venetoclax	1	Completed	1
DB14975	Voxelotor	1	Completed	1
DB06629	Zibotentan	1	Completed	1
DB13090	Zidebactam	1	Completed	1
DB11777	Cenderitide	1 / 2	Completed	1
DB09261	Certoparin	1 / 2	Completed	1
DB00073	Rituximab	1 / 2	Completed	1
DB00820	Tadalafil	1 / 2	Completed	2
DB05253	Telapristone acetate	1 / 2	Terminated	1
DB04876	Vildagliptin	1 / 2	Completed	1
DB00316	Acetaminophen	2	Not Yet Recruiting	1
DB06151	Acetylcysteine	2	Completed	1
DB00640	Adenosine	2	Terminated	1
DB00062	Albumin human	2	Unknown Status	1
DB00188	Bortezomib	2	Completed	2
DB00188	Bortezomib	2	Not Yet Recruiting	1
DB08889	Carfilzomib	2	Completed	1
DB00310	Chlorthalidone	2	Recruiting	1
DB00565	Cisatracurium	2	Active Not Recruiting	1
DB15194	Cotadutide	2	Completed	1
DB00531	Cyclophosphamide	2	Not Yet Recruiting	1
DB09102	Daclatasvir	2	Withdrawn	1
DB01234	Dexamethasone	2	Completed	2
DB01234	Dexamethasone	2	Not Yet Recruiting	2
DB01234	Dexamethasone	2	Terminated	1
DB01075	Diphenhydramine	2	Not Yet Recruiting	1
DB00841	Dobutamine	2	Terminated	1
DB00997	Doxorubicin	2	Completed	1
DB12625	Evogliptin	2	Completed	1
DB04854	Febuxostat	2	Completed	1
DB05059	ILY101	2	Unknown Status	1
DB14811	Isatuximab	2	Not Yet Recruiting	2
DB00480	Lenalidomide	2	Completed	1
DB00480	Lenalidomide	2	Not Yet Recruiting	1
DB15048	Licogliflozin	2	Completed	1
DB08882	Linagliptin	2	Completed	1
DB00235	Milrinone	2	Terminated	1
DB01400	Neostigmine	2	Active Not Recruiting	1
DB04899	Nesiritide	2	Completed	1
DB04899	Nesiritide	2	Terminated	1
DB08910	Pomalidomide	2	Not Yet Recruiting	1
DB00863	Ranitidine	2	Not Yet Recruiting	1
DB00728	Rocuronium	2	Active Not Recruiting	1
DB12670	Rolofylline	2	Completed	1
DB06290	Simeprevir	2	Withdrawn	1
DB01390	Sodium bicarbonate	2	Completed	1
DB09153	Sodium chloride	2	Completed	1
DB09153	Sodium chloride	2	Terminated	1
DB00421	Spironolactone	2	Recruiting	1
DB06206	Sugammadex	2	Active Not Recruiting	1
DB12569	Tonapofylline	2	Terminated	1
DB12353	Ulodesine	2	Completed	1
DB01590	Everolimus	2 / 3	Unknown Status	1
DB05640	Tonapofylline	2 / 3	Completed	1
DB12569	Tonapofylline	2 / 3	Completed	1
DB06605	Apixaban	3	Terminated	1
DB01076	Atorvastatin	3	Completed	2
DB00074	Basiliximab	3	Completed	1
DB15200	Bixalomer	3	Completed	5
DB08907	Canagliflozin	3	Completed	1
DB11723	Dutogliptin	3	Terminated	1
DB09038	Empagliflozin	3	Completed	1
DB08917	Ferric carboxymaltose	3	Completed	1
DB00695	Furosemide	3	Completed	2
DB01109	Heparin	3	Terminated	1
DB05059	ILY101	3	Completed	3
DB09146	Iron sucrose	3	Completed	1
DB06792	Lanthanum carbonate	3	Completed	1
DB00583	Levocarnitine	3	Terminated	1
DB00678	Losartan	3	Completed	1
DB00688	Mycophenolate mofetil	3	Completed	1
DB00275	Olmesartan	3	Completed	1
DB01022	Phylloquinone	3	Terminated	1
DB06228	Rivaroxaban	3	Terminated	1
DB00658	Sevelamer	3	Completed	1
DB00877	Sirolimus	3	Completed	1
DB01261	Sitagliptin	3	Completed	1
DB01261	Sitagliptin	3	Terminated	1
DB01390	Sodium bicarbonate	3	Terminated	1
DB09153	Sodium chloride	3	Terminated	1
DB00864	Tacrolimus	3	Active Not Recruiting	1
DB14520	Tetraferric tricitrate decahydrate	3	Completed	1
DB04876	Vildagliptin	3	Completed	2
DB00062	Albumin human	4	Terminated	1
DB00437	Allopurinol	4	Completed	1
DB00770	Alprostadil	4	Unknown Status	1
DB00098	Antithymocyte immunoglobulin (rabbit)	4	Terminated	1
DB01053	Benzylpenicillin	4	Terminated	1
DB01164	Calcium chloride	4	Completed	1
DB01197	Captopril	4	Unknown Status	1
DB00169	Cholecalciferol	4	Unknown Status	1
DB01147	Cloxacillin	4	Terminated	1
DB00531	Cyclophosphamide	4	Terminated	1
DB06292	Dapagliflozin	4	Unknown Status	1
DB00080	Daptomycin	4	Terminated	1
DB08826	Deferiprone	4	Completed	1
DB08930	Dolutegravir	4	Recruiting	1
DB12301	Doravirine	4	Recruiting	1
DB09038	Empagliflozin	4	Completed	1
DB01225	Enoxaparin	4	Completed	1
DB01590	Everolimus	4	Terminated	1
DB00973	Ezetimibe	4	Completed	1
DB00569	Fondaparinux	4	Terminated	1
DB11728	Fondaparinux	4	Terminated	1
DB00996	Gabapentin	4	Terminated	1
DB06703	Gadobutrol	4	Completed	1
DB00225	Gadodiamide	4	Completed	1
DB09132	Gadoteric acid	4	Completed	1
DB00999	Hydrochlorothiazide	4	Completed	1
DB01050	Ibuprofen	4	Completed	1
DB00702	Icodextrin	4	Completed	1
DB00808	Indapamide	4	Completed	1
DB09564	Insulin degludec	4	Recruiting	1
DB00047	Insulin glargine	4	Completed	1
DB00047	Insulin glargine	4	Recruiting	1
DB01309	Insulin glulisine	4	Completed	1
DB00030	Insulin human	4	Completed	1
DB01249	Iodixanol	4	Completed	1
DB01249	Iodixanol	4	Terminated	2
DB01249	Iodixanol	4	Withdrawn	1
DB08947	Iopamidol	4	Terminated	1
DB09156	Iopromide	4	Withdrawn	1
DB09134	Ioversol	4	Terminated	1
DB09134	Ioversol	4	Withdrawn	1
DB04398	Lactic acid	4	Completed	1
DB00709	Lamivudine	4	Recruiting	1
DB01202	Levetiracetam	4	Completed	1
DB00922	Levosimendan	4	Unknown Status	1
DB08882	Linagliptin	4	Completed	1
DB09407	Magnesium chloride	4	Completed	1
DB00331	Metformin	4	Unknown Status	1
DB00295	Morphine	4	Terminated	1
DB00688	Mycophenolate mofetil	4	Terminated	1
DB01024	Mycophenolic acid	4	Completed	1
DB00607	Nafcillin	4	Terminated	1
DB00713	Oxacillin	4	Terminated	1
DB00497	Oxycodone	4	Completed	1
DB00497	Oxycodone	4	Terminated	1
DB00860	Prednisolone	4	Completed	1
DB00073	Rituximab	4	Terminated	1
DB00641	Simvastatin	4	Completed	1
DB09153	Sodium chloride	4	Completed	1
DB00421	Spironolactone	4	Unknown Status	1
DB00864	Tacrolimus	4	Completed	1
DB00864	Tacrolimus	4	Recruiting	1
DB00864	Tacrolimus	4	Terminated	2
DB09299	Tenofovir alafenamide	4	Recruiting	1
DB00300	Tenofovir disoproxil	4	Recruiting	2
DB14520	Tetraferric tricitrate decahydrate	4	Completed	1
DB00512	Vancomycin	4	Terminated	1
DB04876	Vildagliptin	4	Unknown Status	1
DB00945	Acetylsalicylic acid	Not Available	Completed	1
DB00630	Alendronic acid	Not Available	Completed	1
DB00125	Arginine	Not Available	Recruiting	1
DB00612	Bisoprolol	Not Available	Recruiting	1
DB01373	Calcium	Not Available	Completed	1
DB06724	Calcium carbonate	Not Available	Completed	1
DB01164	Calcium chloride	Not Available	Completed	1
DB11093	Calcium citrate	Not Available	Completed	1
DB14733	Ceftobiprole medocaril	Not Available	Recruiting	1
DB01394	Colchicine	Not Available	Active Not Recruiting	1
DB00148	Creatine	Not Available	Completed	1
DB06779	Dalteparin	Not Available	Completed	1
DB00016	Erythropoietin	Not Available	Completed	1
DB00789	Gadopentetic acid	Not Available	Completed	1
DB09106	Hydroxyethyl Starch	Not Available	Completed	1
DB01362	Iohexol	Not Available	Completed	1
DB01221	Ketamine	Not Available	Completed	1
DB06218	Lacosamide	Not Available	Completed	1
DB04398	Lactic acid	Not Available	Completed	1
DB01202	Levetiracetam	Not Available	Completed	1
DB00601	Linezolid	Not Available	Completed	1
DB09107	Methoxy polyethylene glycol-epoetin beta	Not Available	Completed	1
DB00727	Nitroglycerin	Not Available	Recruiting	1
DB01174	Phenobarbital	Not Available	Completed	1
DB00252	Phenytoin	Not Available	Completed	1
DB00761	Potassium chloride	Not Available	Completed	1
DB06228	Rivaroxaban	Not Available	Unknown Status	1
DB01001	Salbutamol	Not Available	Recruiting	1
DB09153	Sodium chloride	Not Available	Completed	1
DB00966	Telmisartan	Not Available	Recruiting	1
DB00313	Valproic acid	Not Available	Completed	1
DB11094	Vitamin D	Not Available	Completed	1
DB00399	Zoledronic acid	Not Available	Completed	1