Quinolines
- Name
- Quinolines
- Accession Number
- DBCAT000788
- Description
Cyclic compounds that include atoms other than carbon in their ring structure.
- ATC Classification
- Drugs
Drug Drug Description 1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone Not Available 2-heptyl-4-hydroxyquinoline N-oxide Not Available 2-Hydroxyquinoline Not Available 5,7-Dichlorokynurenic acid Not Available Abanoquil Abanoquil is a small molecule drug. Abanoquil has a monoisotopic molecular weight of 395.18 Da. Abediterol Abediterol has been used in trials studying the treatment of Asthma, Chronic Obstructive Pulmonary Disease (COPD), and Chronic Obstructive Pulmonary Disease (COPD) and Asthma. Acloproxalap Acloproxalap is a small molecule drug. Acloproxalap is under investigation in clinical trial NCT06685692 (A Clinical Trial Investigating the Safety and Efficacy of Subjects With Alcohol Associated Hepatitis (Part 1)).... Acodazole Acodazole is a small molecule drug. Acodazole has a monoisotopic molecular weight of 345.16 Da. Acorafloxacin Acorafloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Acorafloxacin is a nalidixic acid derivative antibacterial. Acorafloxacin has a monoisotopic molecular... Alatrofloxacin A fluoroquinolone antibiotic used to treat a variety of bacterial infections. Alilusem Alilusem is a small molecule drug. Alilusem has a monoisotopic molecular weight of 394.04 Da. Amfonelic acid Amfonelic acid is a small molecule drug. Amfonelic acid has a monoisotopic molecular weight of 308.12 Da. Amifloxacin Amifloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Amifloxacin is a nalidixic acid derivative antibacterial. Amifloxacin has a monoisotopic molecular... Amiquinsin Amiquinsin is a small molecule drug. Amiquinsin has a monoisotopic molecular weight of 204.09 Da. Amodiaquine An antimalarial drug. Amquinate Amquinate is a small molecule drug. Amquinate has a monoisotopic molecular weight of 316.18 Da. Aripiprazole An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. Aripiprazole lauroxil An antipsychotic used to treat schizophrenia in adults. Batefenterol Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive. Bedaquiline A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). Benzoxiquine Benzoxiquine is a small molecule drug. Benzoxiquine has a monoisotopic molecular weight of 249.08 Da. Besifloxacin A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis. Bexlosteride Bexlosteride is a small molecule drug. The usage of the INN stem '-steride' in the name indicates that Bexlosteride is a androgen/anabolic steroid. Bexlosteride has a monoisotopic molecular weight of... BMS-223131 Not Annotated Brequinar Not Available Brexpiprazole A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease. Broxaldine Broxaldine is a small molecule drug. Broxaldine has a monoisotopic molecular weight of 418.92 Da. Broxyquinoline Not Annotated Buquinolate Not Annotated Carmoterol A long acting beta-2 agonist indicated in the treatment of COPD, asthma, and chronic bronchitis. Carteolol A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. Casimiroin Casimiroin is a quinone reductase 2 inhibitor isolated from Casimiroa edulis. Chiniofon Not Annotated Chloroquine An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. Chloroxine An antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp. Chlorquinaldol Chlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment... Cilostamide Cilostamide is a small molecule drug. Cilostamide has a monoisotopic molecular weight of 342.19 Da. Cilostazol An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication. Cinchocaine An anesthetic used for local or regional anesthesia. Ciprofloxacin A second generation fluoroquinolone used to treat various susceptible bacterial infections. Clinafloxacin Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of... Clioquinol An antifungal cream used to treat a variety of fungal infections. Cloxyquin Not Annotated CP-609754 LNK 754 has been investigated in Mild Alzheimer's Disease. Danofloxacin Danofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine. Decoquinate Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites. Delafloxacin A fluoroquinolone antibiotic used to treat skin and skin structure infections. Dequalinium A quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat, as well as vaginal candidiasis. Desidustat Desidustat is under investigation in clinical trial NCT04012957 (Desidustat in the Treatment of Anemia in CKD). Difloxacin Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced... Diiodohydroxyquinoline Used in the treatment of amoebiasis. Dovitinib Investigated for use/treatment in multiple myeloma and solid tumors. Ecenofloxacin Ecenofloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Ecenofloxacin is a nalidixic acid derivative antibacterial. Ecenofloxacin has a monoisotopic molecular... Elvitegravir An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Enoxacin For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria... Enrofloxacin Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant... Ethoxyquin Not Annotated Finafloxacin Finafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1... Fleroxacin Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. Florifenine Florifenine is a small molecule drug. Florifenine has a monoisotopic molecular weight of 429.17 Da. Flumequine Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. Garenoxacin Investigated for use/treatment in bacterial infection. Gatifloxacin A fourth generation fluoroquinolone used to treat a wide variety of infections in the body. Gemifloxacin A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria. Grepafloxacin A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections. GSK-256066 Gsk256066 has been used in trials studying the treatment and diagnostic of SAR, Asthma, Mild Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis, among others. Hydroquinidine A medication indicated in the maintenance of a normal sinus rhythm, as well as the treatment and prevention of abnormal rhythm. Hydroquinine Not Annotated Hydroxychloroquine An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus. Imiquimod A toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata. Indacaterol An inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma. Ipidacrine Not Annotated Irloxacin Irloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Irloxacin is a nalidixic acid derivative antibacterial. Irloxacin has a monoisotopic molecular... Ivacaftor A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. JTC-801 free base An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment. Kynurenic Acid Kynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers). Laquinimod Investigated for use/treatment in multiple sclerosis. Lascufloxacin Lascufloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Lascufloxacin is a nalidixic acid derivative antibacterial. Lascufloxacin has a monoisotopic molecular... Levofloxacin A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. Levonadifloxacin Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)). LGD-2226 An androgen receptor modulator. LGD-3303 An androgen receptor modulator. LGD2941 For the treatment and prevention of osteoporosis. Lomefloxacin A fluoroquinolone used to prevent and treat a wide variety of infections in the body. LY-3023414 LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others. Marbofloxacin Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available... Mavorixafor A CXC chemokine receptor 4 antagonist used to treat WHIM syndrome. Mefloquine An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax. Miloxacin Miloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Miloxacin is a nalidixic acid derivative antibacterial. Miloxacin has a monoisotopic molecular... Minocromil Minocromil is a small molecule drug. Minocromil has a monoisotopic molecular weight of 356.1 Da. Moxifloxacin A fluoroquinolone antibiotic used to treat various bacterial infections. Nadifloxacin A topical fluoroquinolone used in the treatment of acne and topical bacterial skin infections. Nalidixic acid A quinolone antibiotic used to treat urinary tract infections. Nanterinone Nanterinone is a small molecule drug. Nanterinone has a monoisotopic molecular weight of 253.12 Da. Naphthoquine Naphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO). Nedocromil A pyrano quinoline used to treat allergic conjunctivitis. Nemonoxacin Investigated for use/treatment in bacterial infection and pneumonia. Nequinate Nequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. Nequinate belongs to the family of Hydroquinolones. These are compounds containing an hydrogenated quinoline bearing a ketone group. Nitroxoline Nitroxoline is an antibiotic agent. Norfloxacin A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine. NSC-663284 NSC-663284 is a potent quinolinedione Cdc25 phosphatase inhibitor. Ofloxacin An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. OPC-14523 Investigated for use/treatment in bulimia, depression, and obsessive-compulsive disorders. Orbifloxacin Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs. Oxamniquine For treatment of Schistosomiasis caused by Schistosoma mansoni Oxolinic acid Not Annotated Oxycinchophen Not Annotated Oxyquinoline A medication used in combination with other medications to restore vaginal pH. Ozenoxacin A quinolone antibiotic used to treat impetigo caused by susceptible bacteria. Paltusotine A somatostatin receptor agonist used to treat acromegaly in adults whose surgery is not an option or has not been effective. Pavinetant Pavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia. Pazufloxacin Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol). Pefloxacin An antibiotic used to treat a variety of bacterial infections. Pelitinib Investigated for use/treatment in colorectal cancer and lung cancer. Pentaquine Pentaquine is a small molecule drug. Pentaquine has a monoisotopic molecular weight of 301.22 Da. Pradofloxacin Pradofloxacin is a 3rd generation fluoroquinolone antibiotic developed by Bayer HealthCare AG, Animal Health GmBH. It was approved by the European Commission in April 2011 for bacterial infections in dogs... Primaquine An antimalarial indicated to prevent relapse of vivax malaria. Procaterol A beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Prulifloxacin A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections. PSI-697 PSI-697 has been used in trials studying the treatment of Scleritis. Pyrotinib Pyrotinib is under investigation in clinical trial NCT03756064 (Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer). Pyrroloquinoline Quinone A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. [PubChem] Pyrvinium An anthelmintic agent used for the treatment of pinworm infestations. Quarfloxin Investigated for use/treatment in leukemia (lymphoid). Quinagolide A dopamine D2 receptor agonist used for the treatment of hyperprolactinemia. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Quinine An alkaloid used to treat uncomplicated Plasmodium falciparum malaria. Quinpirole Quinpirole is a small molecule drug. Quinpirole has a monoisotopic molecular weight of 219.17 Da. Quipazine Quipazine is a small molecule drug. Quipazine has a monoisotopic molecular weight of 213.13 Da. Rebamipide A gastroprotective agent used in combination with other similar therapies (e.g. proton pump inhibitors) to treat gastritis and protect the gastric mucosa. Repirinast Repirinast is a small molecule drug. Repirinast has a monoisotopic molecular weight of 355.14 Da. Reproxalap Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis, and Sjögren-Larsson syndrome. NS-2... Rilapladib Investigated for use/treatment in atherosclerosis and cardiovascular disorders. Ritolukast Ritolukast is a small molecule drug. The usage of the INN stem '-lukast' in the name indicates that Ritolukast is a leukotriene receptor antagonist. Ritolukast has a monoisotopic molecular weight... Roquinimex Roquinimex is investigated to be used as a treatment of a number of cancers and autoimmune conditions. As well, roquinimex is researched to be used as adjuvant therapy after bone... Rosoxacin For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rufloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible respiratory infections and uncomplicated cystitis. Saquinavir An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. Sarafloxacin Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada. Setrobuvir Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic. Sitafloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections. Sitamaquine Investigated for use/treatment in infectious and parasitic disease (unspecified). Sparfloxacin A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis. Tafenoquine An antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria. Tasquinimod Investigated for use/treatment in prostate cancer. TBAJ-876 Not Available Tebuquine Tebuquine is a small molecule drug. Tebuquine has a monoisotopic molecular weight of 465.14 Da. Technetium Tc-99m ciprofloxacin Investigated for use/treatment in infectious and parasitic disease (unspecified). Temafloxacin For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. Tilbroquinol Tilbroquinol was approved in France, Morocco, and Saudi Arabia but it has been withdrawn in France and Saudi Arabia markets mainly due to its hepatotoxicity risk outweighing the drug benefit... Tiliquinol Tiliquinol is a small molecule drug. Tiliquinol has a monoisotopic molecular weight of 159.07 Da. Tipifarnib Investigated for use/treatment in colorectal cancer, leukemia (myeloid), pancreatic cancer, and solid tumors. TNP-2092 TNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection). Tosufloxacin Not Annotated Trovafloxacin An antibiotic used to treat gonorrhea and chlamydia. Zabofloxacin Zabofloxacin has been used in trials studying the treatment of Community Acquired Pneumonia and Chronic Obstructive Pulmonary Disease. Zavegepant A calcitonin gene-related peptide receptor antagonist indicated for the acute treatment of migraine with or without aura.