Quinolines

Name
Quinolines
Accession Number
DBCAT000788
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
MoxifloxacinA fluoroquinolone antibiotic used to treat various bacterial infections.
MefloquineAn antimalarial agent used as a schizonticidal agent.
GrepafloxacinA fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
EnoxacinFor the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria...
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
PefloxacinFor the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
CarteololA beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
CinchocaineAn anesthetic used for local or regional anesthesia.
CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
ChloroquineAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
AmodiaquineFor treatment of acute malarial attacks in non-immune subjects.
TrovafloxacinAn antibiotic used to treat gonorrhea and chlamydia.
NedocromilA pyrano quinoline used to treat allergic conjunctivitis.
ImiquimodA toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.
Nalidixic acidA quinolone antibiotic used to treat urinary tract infections.
RosoxacinFor the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
LomefloxacinA fluoroquinolone used to prevent and treat a wide variety of infections in the body.
GatifloxacinA fourth generation fluoroquinolone used to treat a wide variety of infections in the body.
NorfloxacinA broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.
PrimaquineAn antimalarial indicated to prevent relapse of vivax malaria.
OxamniquineFor treatment of Schistosomiasis caused by Schistosoma mansoni
LevofloxacinA fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.
GemifloxacinA quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.
OfloxacinAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
SparfloxacinFor the treatment of adults with the following infections caused by susceptible strains microorganisms: community-acquired pneumonia (caused by Chlamydia pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, or Streptococcus...
SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
AripiprazoleAn atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
ChloroxineAn antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
ProcaterolA beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
TemafloxacinFor the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
NitroxolineNitroxoline is an antibiotic agent.
HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
DequaliniumA quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat that has been studied in the treatment of vaginal candidiasis.
FleroxacinFleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
ClioquinolAn antifungal cream used to treat a variety of fungal infections.
SitamaquineInvestigated for use/treatment in infectious and parasitic disease (unspecified).
TipifarnibInvestigated for use/treatment in colorectal cancer, leukemia (myeloid), pancreatic cancer, and solid tumors.
IndacaterolAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
RilapladibInvestigated for use/treatment in atherosclerosis and cardiovascular disorders.
LGD2941For the treatment and prevention of osteoporosis.
OPC-14523Investigated for use/treatment in bulimia, depression, and obsessive-compulsive disorders.
Technetium Tc-99m ciprofloxacinInvestigated for use/treatment in infectious and parasitic disease (unspecified).
PelitinibInvestigated for use/treatment in colorectal cancer and lung cancer.
DovitinibInvestigated for use/treatment in multiple myeloma and solid tumors.
GarenoxacinInvestigated for use/treatment in bacterial infection.
NemonoxacinInvestigated for use/treatment in bacterial infection and pneumonia.
TafenoquineAn antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.
QuarfloxinInvestigated for use/treatment in leukemia (lymphoid).
LaquinimodInvestigated for use/treatment in multiple sclerosis.
BesifloxacinA fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.
PyrviniumAn anthelmintic agent used for the treatment of pinworm infestations.
LGD-2226An androgen receptor modulator.
IvacaftorA cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication.
BedaquilineA diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB).
FlumequineFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
FinafloxacinFinafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1...
QuinagolideA dopamine D2 receptor agonist used for the treatment of hyperprolactinemia.
ElvitegravirAn antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
DiiodohydroxyquinolineUsed in the treatment of amoebiasis.
BrexpiprazoleA serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct and schizophrenia.
AlatrofloxacinA fluoroquinolone antibiotic used to treat a variety of bacterial infections.
OxyquinolineA medication used in combination with other medications to restore vaginal pH.
RoquinimexRoquinimex is investigated to be used as a treatment of a number of cancers and autoimmune conditions. As well, roquinimex is researched to be used as adjuvant therapy after bone...
BuquinolateNot Annotated
DanofloxacinDanofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary.
DecoquinateDecoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
EnrofloxacinEnrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant...
MarbofloxacinMarbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under...
NequinateNequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. Nequinate belongs to the family of Hydroquinolones. These are compounds containing an hydrogenated quinoline bearing a ketone group.
OrbifloxacinOrbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
PradofloxacinPradofloxacin is a 3rd generation fluoroquinolone antibiotic developed by Bayer HealthCare AG, Animal Health GmBH. It was approved by the European Commission in April 2011 for bacterial infections in dogs...
SarafloxacinSarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
DifloxacinDifloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced...
RebamipideRebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
PavinetantPavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia.
PazufloxacinPazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).
PrulifloxacinPrulifloxacin has been investigated for the treatment of Urinary Tract Infection.
Kynurenic AcidKynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).
DelafloxacinA fluoroquinolone antibiotic used to treat skin and skin structure infections.
SetrobuvirSetrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
AbediterolAbediterol has been used in trials studying the treatment of Asthma, Chronic Obstructive Pulmonary Disease (COPD), and Chronic Obstructive Pulmonary Disease (COPD) and Asthma.
GSK-256066Gsk256066 has been used in trials studying the treatment and diagnostic of SAR, Asthma, Mild Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis, among others.
PSI-697PSI-697 has been used in trials studying the treatment of Scleritis.
NadifloxacinNadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
ZabofloxacinZabofloxacin has been used in trials studying the treatment of Community Acquired Pneumonia and Chronic Obstructive Pulmonary Disease.
CP-609754LNK 754 has been investigated in Mild Alzheimer's Disease.
OzenoxacinA quinolone antibiotic used to treat impetigo caused by susceptible bacteria.
TilbroquinolTilbroquinol was approved in France, Morocco, and Saudi Arabia but it has been withdrawn in France and Saudi Arabia markets mainly due to its hepatotoxicity risk outweighing the drug benefit...
SitafloxacinNot Annotated
ChlorquinaldolChlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment...
ChiniofonNot Annotated
BroxyquinolineNot Annotated
Oxolinic acidNot Annotated
IpidacrineNot Annotated
HydroquinineNot Annotated
RufloxacinRufloxacin is a quinolone antibiotic.
LGD-3303An androgen receptor modulator.
ClinafloxacinClinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of...
OxycinchophenNot Annotated
Aripiprazole lauroxilAn antipsychotic used to treat schizophrenia in adults.
HydroquinidineHydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
TasquinimodInvestigated for use/treatment in prostate cancer.
LY-3023414LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
BatefenterolBatefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
PyrotinibPyrotinib is under investigation in clinical trial NCT03756064 (Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer).
5,7-Dichlorokynurenic acidNot Available
1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinoneNot Available
2-heptyl-4-hydroxyquinoline N-oxideNot Available
2-HydroxyquinolineNot Available
CasimiroinCasimiroin is a quinone reductase 2 inhibitor isolated from Casimiroa edulis.
VazegepantVazegepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor currently in phase 3 trials in an intranasal formulation for the treatment of migraine. If FDA approved, it will...
CarmoterolNot Annotated
Drugs & Drug Targets
DrugTargetType
MoxifloxacinDNA gyrase subunit Atarget
MoxifloxacinDNA topoisomerase 4 subunit Atarget
MoxifloxacinDNA topoisomerase 2-alphatarget
MoxifloxacinCytochrome P450 1A2enzyme
MefloquineCholinesteraseenzyme
MefloquineCytochrome P450 3A4enzyme
MefloquineAdenosine receptor A2atarget
MefloquineFe(II)-protoporphyrin IXtarget
MefloquineP-glycoprotein 1transporter
MefloquineCytochrome P450 19A1enzyme
MefloquineAcetylcholinesteraseenzyme
Mefloquine80S ribosomal subunittarget
GrepafloxacinDNA gyrase subunit Atarget
GrepafloxacinDNA topoisomerase 4 subunit Atarget
GrepafloxacinCytochrome P450 3A4enzyme
GrepafloxacinCytochrome P450 1A2enzyme
GrepafloxacinSolute carrier family 22 member 2transporter
GrepafloxacinSolute carrier family 22 member 5transporter
GrepafloxacinCanalicular multispecific organic anion transporter 1transporter
GrepafloxacinP-glycoprotein 1transporter
GrepafloxacinMultidrug resistance-associated protein 1transporter
GrepafloxacinSolute carrier family 22 member 6transporter
EnoxacinDNA gyrase subunit Atarget
EnoxacinDNA topoisomerase 4 subunit Atarget
EnoxacinDNA topoisomerase 2-alphatarget
EnoxacinCytochrome P450 1A2enzyme
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
PefloxacinDNA gyrase subunit Atarget
PefloxacinDNA topoisomerase 4 subunit Atarget
PefloxacinDNA topoisomerase 2-alphatarget
PefloxacinCytochrome P450 1A2enzyme
PefloxacinDNA topoisomerase 1target
CarteololBeta-2 adrenergic receptortarget
CarteololBeta-1 adrenergic receptortarget
CarteololCytochrome P450 2D6enzyme
CinchocaineSodium channel protein type 5 subunit alphatarget
CinchocaineSodium channel protein type 10 subunit alphatarget
CinchocaineCalmodulintarget
CinchocaineCholinesteraseenzyme
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Atarget
CiprofloxacinDNA topoisomerase 2-alphatarget
CiprofloxacinCytochrome P450 1A2enzyme
CiprofloxacinCytochrome P450 3A4enzyme
CiprofloxacinCytochrome P450 3A5enzyme
CiprofloxacinCytochrome P450 3A7enzyme
CiprofloxacinP-glycoprotein 1transporter
CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Btarget
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinMultidrug resistance protein MdtKtarget
CiprofloxacinGyrase Atarget
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinMultidrug and toxin extrusion protein 1transporter
CiprofloxacinMultidrug and toxin extrusion protein 2transporter
CiprofloxacinSerum albumincarrier
ChloroquineTumor necrosis factortarget
ChloroquineToll-like receptor 9target
ChloroquineGlutathione S-transferase A2target
ChloroquineCytochrome P450 2D6enzyme
ChloroquineCytochrome P450 3A4enzyme
ChloroquineCytochrome P450 1A1enzyme
ChloroquineCytochrome P450 2C8enzyme
ChloroquineCytochrome P450 3A5enzyme
ChloroquineGlutathione S-transferasetarget
ChloroquineP-glycoprotein 1transporter
ChloroquineSerum albumincarrier
Chloroquinealpha1-acid glycoproteincarrier
ChloroquineHigh mobility group protein B1target
ChloroquineGlutathione S-transferase Mu 1target
ChloroquineAngiotensin-converting enzyme 2target
AmodiaquineHistamine N-methyltransferasetarget
AmodiaquineCytochrome P450 2C8enzyme
AmodiaquineCytochrome P450 2D6enzyme
AmodiaquineFe(II)-protoporphyrin IXtarget
AmodiaquineCytochrome P450 1A1enzyme
AmodiaquineCytochrome P450 1B1enzyme
AmodiaquineCytochrome P450 2C9enzyme
AmodiaquineP-glycoprotein 1transporter
TrovafloxacinDNA gyrase subunit Atarget
TrovafloxacinDNA topoisomerase 4 subunit Atarget
TrovafloxacinDNA topoisomerase 2-alphatarget
TrovafloxacinCytochrome P450 1A2enzyme
NedocromilCysteinyl leukotriene receptor 1target
NedocromilCysteinyl leukotriene receptor 2target
NedocromilProstaglandin D2 receptortarget
NedocromilfMet-Leu-Phe receptortarget
NedocromilHeat shock protein HSP 90-alphatarget
ImiquimodToll-like receptor 7target
ImiquimodToll-like receptor 8target
ImiquimodCytochrome P450 3A4enzyme
Nalidixic acidDNAtarget
Nalidixic acidSolute carrier family 22 member 6transporter
Nalidixic acidTryptophan 2,3-dioxygenaseenzyme
Nalidixic acidCytochrome P450 1A2enzyme
RosoxacinDNA topoisomerase 4 subunit Atarget
RosoxacinDNA gyrase subunit Btarget
RosoxacinCytochrome P450 1A2enzyme
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
LomefloxacinDNA gyrase subunit Atarget
LomefloxacinDNA topoisomerase 4 subunit Atarget
LomefloxacinDNA topoisomerase 2-alphatarget
LomefloxacinCytochrome P450 1A2enzyme
LomefloxacinSolute carrier family 22 member 5transporter
LomefloxacinCanalicular multispecific organic anion transporter 1transporter
GatifloxacinSerum albumincarrier
GatifloxacinDNA gyrase subunit Atarget
GatifloxacinDNA gyrase subunit Btarget
GatifloxacinDNA topoisomerase 4 subunit Atarget
GatifloxacinDNA topoisomerase 4 subunit Btarget
GatifloxacinCytochrome P450 1A2enzyme
NorfloxacinDNA gyrase subunit Atarget
NorfloxacinDNA topoisomerase 4 subunit Atarget
NorfloxacinDNA topoisomerase 2-alphatarget
NorfloxacinCytochrome P450 1A2enzyme
NorfloxacinCytochrome P450 3A4enzyme
NorfloxacinSolute carrier family 22 member 5transporter
NorfloxacinSolute carrier family 22 member 6transporter
NorfloxacinCytochrome P450 1A1enzyme
PrimaquineCytochrome P450 1A1enzyme
PrimaquineCytochrome P450 1A2enzyme
PrimaquineCytochrome P450 3A4enzyme
PrimaquineKeratin, type II cytoskeletal 7target
PrimaquineCytochrome P450 1B1enzyme
PrimaquineCytochrome P450 2D6enzyme
PrimaquineRibosyldihydronicotinamide dehydrogenase [quinone]target
PrimaquineFe(II)-protoporphyrin IXtarget
PrimaquineP-glycoprotein 1transporter
OxamniquineDNAtarget
OxamniquineCytochrome P450 2D6enzyme
LevofloxacinDNA gyrase subunit Atarget
LevofloxacinDNA topoisomerase 4 subunit Atarget
LevofloxacinCytochrome P450 1A2enzyme
LevofloxacinSolute carrier family 22 member 2transporter
LevofloxacinP-glycoprotein 1transporter
LevofloxacinSolute carrier family 22 member 4transporter
LevofloxacinMultidrug and toxin extrusion protein 1transporter
LevofloxacinMultidrug and toxin extrusion protein 2transporter
LevofloxacinCytochrome P450 2C9enzyme
LevofloxacinSerum albumincarrier
LevofloxacinSolute carrier organic anion transporter family member 4C1transporter
LevofloxacinSolute carrier family 22 member 1transporter
LevofloxacinSolute carrier organic anion transporter family member 1A2transporter
GemifloxacinDNA gyrase subunit Atarget
GemifloxacinDNA topoisomerase 4 subunit Atarget
GemifloxacinCytochrome P450 1A2enzyme
OfloxacinDNA gyrase subunit Atarget
OfloxacinDNA topoisomerase 4 subunit Atarget
OfloxacinDNA topoisomerase 2-alphatarget
OfloxacinCytochrome P450 1A2enzyme
OfloxacinSolute carrier family 22 member 5transporter
OfloxacinMultidrug resistance-associated protein 1transporter
OfloxacinSolute carrier family 22 member 6transporter
OfloxacinCanalicular multispecific organic anion transporter 1transporter
OfloxacinSolute carrier family 22 member 4transporter
OfloxacinBile salt export pumptransporter
SparfloxacinDNA gyrase subunit Atarget
SparfloxacinDNA topoisomerase 4 subunit Atarget
SparfloxacinDNA topoisomerase 2-alphatarget
SparfloxacinSolute carrier family 22 member 5transporter
SparfloxacinCanalicular multispecific organic anion transporter 1transporter
SparfloxacinP-glycoprotein 1transporter
SparfloxacinCytochrome P450 1A2enzyme
SaquinavirHuman immunodeficiency virus type 1 proteasetarget
SaquinavirCytochrome P450 3A4enzyme
SaquinavirCytochrome P450 3A5enzyme
SaquinavirAlpha-1-acid glycoprotein 1carrier
SaquinavirSerum albumincarrier
SaquinavirCytochrome P450 3A7enzyme
SaquinavirP-glycoprotein 1transporter
SaquinavirSolute carrier family 22 member 1transporter
SaquinavirSolute carrier organic anion transporter family member 1A2transporter
SaquinavirATP-binding cassette sub-family G member 2transporter
SaquinavirSolute carrier organic anion transporter family member 1B1transporter
SaquinavirMultidrug resistance-associated protein 1transporter
SaquinavirCanalicular multispecific organic anion transporter 1transporter
SaquinavirCytochrome P450 2C8enzyme
SaquinavirCytochrome P450 2D6enzyme
SaquinavirSolute carrier organic anion transporter family member 2B1transporter
SaquinavirBile salt export pumptransporter
AripiprazoleDopamine D2 receptortarget
Aripiprazole5-hydroxytryptamine receptor 1Atarget
Aripiprazole5-hydroxytryptamine receptor 2Atarget
AripiprazoleCytochrome P450 3A4enzyme
AripiprazoleCytochrome P450 2D6enzyme
Aripiprazole5-hydroxytryptamine receptor 1Btarget
Aripiprazole5-hydroxytryptamine receptor 1Dtarget
Aripiprazole5-hydroxytryptamine receptor 1Etarget
AripiprazoleDopamine D1 receptortarget
AripiprazoleDopamine D5 receptortarget
AripiprazoleDopamine D3 receptortarget
AripiprazoleDopamine D4 receptortarget
Aripiprazole5-hydroxytryptamine receptor 2Ctarget
Aripiprazole5-hydroxytryptamine receptor 3Atarget
Aripiprazole5-hydroxytryptamine receptor 6target
Aripiprazole5-hydroxytryptamine receptor 7target
AripiprazoleHistamine H1 receptortarget
AripiprazoleAlpha-1A adrenergic receptortarget
AripiprazoleAlpha-1B adrenergic receptortarget
AripiprazoleAlpha-2A adrenergic receptortarget
AripiprazoleAlpha-2B adrenergic receptortarget
AripiprazoleAlpha-2C adrenergic receptortarget
AripiprazoleCytochrome P450 3A5enzyme
AripiprazoleCytochrome P450 3A7enzyme
AripiprazoleSerum albumincarrier
Aripiprazole5-hydroxytryptamine receptor 2Btarget
Aripiprazole5-hydroxytryptamine receptor 5Atarget
AripiprazoleBeta-1 adrenergic receptortarget
AripiprazoleBeta-2 adrenergic receptortarget
AripiprazoleHistamine H2 receptortarget
AripiprazoleHistamine H3 receptortarget
AripiprazoleHistamine H4 receptortarget
AripiprazoleMuscarinic acetylcholine receptor M1target
AripiprazoleMuscarinic acetylcholine receptor M2target
AripiprazoleMuscarinic acetylcholine receptor M3target
AripiprazoleMuscarinic acetylcholine receptor M4target
AripiprazoleMuscarinic acetylcholine receptor M5target
AripiprazoleKappa-type opioid receptortarget
AripiprazoleMu-type opioid receptortarget
AripiprazoleDelta-type opioid receptortarget
AripiprazoleGlutamate (NMDA) receptortarget
AripiprazoleSodium-dependent dopamine transportertarget
AripiprazoleSodium-dependent serotonin transportertarget
ProcaterolBeta-2 adrenergic receptortarget
TemafloxacinDNA gyrase subunit Atarget
TemafloxacinDNA topoisomerase 4 subunit Atarget
TemafloxacinCytochrome P450 1A2enzyme
NitroxolineMethionine aminopeptidase 2target
NitroxolineMagnesium cationtarget
NitroxolineManganese cationtarget
HydroxychloroquineDNAtarget
HydroxychloroquineToll-like receptor 7target
HydroxychloroquineToll-like receptor 9target
HydroxychloroquineCytochrome P450 2D6enzyme
HydroxychloroquineP-glycoprotein 1transporter
HydroxychloroquineSerum albumincarrier
Hydroxychloroquinealpha1-acid glycoproteincarrier
HydroxychloroquineCytochrome P450 3A4enzyme
HydroxychloroquineSolute carrier organic anion transporter family member 1A2transporter
HydroxychloroquineAngiotensin-converting enzyme 2target
HydroxychloroquineCytochrome P450 2C8enzyme
DequaliniumAcriflavine resistance protein Btarget
DequaliniumE3 ubiquitin-protein ligase XIAPtarget
DequaliniumcGMP-gated cation channel alpha-1target
DequaliniumCalcium-activated potassium channel subunit alpha-1target
DequaliniumHTH-type transcriptional regulator QacRtarget
FleroxacinDNA topoisomerase 2-alphatarget
FleroxacinDNA gyrase subunit Atarget
FleroxacinDNA topoisomerase 4 subunit Atarget
TipifarnibProtein farnesyltransferase subunit betatarget
TipifarnibP-glycoprotein 1transporter
IndacaterolBeta-2 adrenergic receptortarget
IndacaterolCytochrome P450 3A4enzyme
IndacaterolUDP-glucuronosyltransferase 1-1enzyme
IndacaterolP-glycoprotein 1transporter
RilapladibPlatelet-activating factor acetylhydrolasetarget
LGD2941Androgen receptortarget
OPC-14523Sodium-dependent serotonin transportertarget
Technetium Tc-99m ciprofloxacinDNA gyrase subunit Btarget
Technetium Tc-99m ciprofloxacinDNA topoisomerase 2-betatarget
Technetium Tc-99m ciprofloxacinCytochrome P450 1A2enzyme
PelitinibEpidermal growth factor receptortarget
DovitinibCytochrome P450 1A1enzyme
DovitinibCytochrome P450 1A2enzyme
DovitinibCanalicular multispecific organic anion transporter 2transporter
DovitinibATP-binding cassette sub-family G member 2transporter
DovitinibUDP-glucuronosyltransferase 1-3enzyme
DovitinibUDP-glucuronosyltransferase 2B7enzyme
DovitinibNuclear receptor subfamily 1 group I member 2target
DovitinibSolute carrier organic anion transporter family member 1B1transporter
DovitinibSolute carrier organic anion transporter family member 2B1transporter
DovitinibCytochrome P450 2C19enzyme
DovitinibCytochrome P450 3A4enzyme
DovitinibSolute carrier organic anion transporter family member 1B3transporter
DovitinibP-glycoprotein 1transporter
GarenoxacinCytochrome P450 1A2enzyme
NemonoxacinCytochrome P450 1A2enzyme
TafenoquineCytochrome P450 2D6enzyme
TafenoquineFerredoxin--NADP reductase, apicoplastenzyme
TafenoquineSolute carrier family 22 member 2transporter
TafenoquineMultidrug and toxin extrusion protein 1transporter
TafenoquineMultidrug and toxin extrusion protein 2transporter
LaquinimodCytochrome P450 3A4enzyme
BesifloxacinDNA topoisomerase 4 subunit Atarget
BesifloxacinDNA topoisomerase 4 subunit Atarget
BesifloxacinDNA gyrase subunit Atarget
BesifloxacinDNA gyrase subunit Atarget
BesifloxacinCytochrome P450 1A2enzyme
LGD-2226Androgen receptortarget
IvacaftorCystic fibrosis transmembrane conductance regulatortarget
IvacaftorCytochrome P450 3A4enzyme
IvacaftorSerum albumincarrier
IvacaftorAlpha-1-acid glycoprotein 1carrier
IvacaftorP-glycoprotein 1transporter
IvacaftorCytochrome P450 3A5enzyme
BedaquilineCytochrome P450 3A4enzyme
BedaquilineATP synthase subunit ctarget
FlumequineCytochrome P450 1A2enzyme
FinafloxacinDNA gyrase subunit Atarget
FinafloxacinDNA topoisomerase 4 subunit Atarget
FinafloxacinDNA topoisomerase 2-alphatarget
QuinagolideDopamine D2 receptortarget
QuinagolideD(1) dopamine receptortarget
ElvitegravirIntegrasetarget
ElvitegravirCytochrome P450 3A4enzyme
ElvitegravirUDP-glucuronosyltransferase 1-4enzyme
BrexpiprazoleCytochrome P450 2D6enzyme
BrexpiprazoleCytochrome P450 3A4enzyme
Brexpiprazole5-hydroxytryptamine receptor 1Atarget
BrexpiprazoleDopamine D2 receptortarget
Brexpiprazole5-hydroxytryptamine receptor 2Atarget
BrexpiprazoleAlpha-2C adrenergic receptortarget
BrexpiprazoleAlpha-1B adrenergic receptortarget
EnrofloxacinCytochrome P450 1A2enzyme
OrbifloxacinCytochrome P450 1A2enzyme
SarafloxacinCytochrome P450 1A2enzyme
DifloxacinCytochrome P450 1A2enzyme
DifloxacinCytochrome P450 1A1enzyme
PavinetantNeuromedin-K receptortarget
PazufloxacinCytochrome P450 1A2enzyme
PrulifloxacinCytochrome P450 1A2enzyme
Kynurenic AcidAryl hydrocarbon receptortarget
Kynurenic AcidG-protein coupled receptor 35target
DelafloxacinUDP-glucuronosyltransferase 1-1enzyme
DelafloxacinUDP-glucuronosyltransferase 1-3enzyme
DelafloxacinUDP-glucuronosyltransferase 2B15enzyme
DelafloxacinDNA topoisomerase 4 subunit Atarget
DelafloxacinDNA gyrase subunit Atarget
DelafloxacinCytochrome P450 2E1enzyme
DelafloxacinCytochrome P450 2C9enzyme
DelafloxacinCytochrome P450 3A4enzyme
DelafloxacinATP-binding cassette sub-family B member 5transporter
DelafloxacinATP-binding cassette sub-family G member 2transporter
DelafloxacinSerum albumincarrier
OzenoxacinDNA gyrase subunit Atarget
OzenoxacinDNA topoisomerase 4 subunit Atarget
SitafloxacinCytochrome P450 1A2enzyme
Oxolinic acidCytochrome P450 1A2enzyme
RufloxacinCytochrome P450 1A2enzyme
ClinafloxacinCytochrome P450 1A2enzyme
ClinafloxacinCytochrome P450 2C19enzyme
ClinafloxacinCytochrome P450 2D6enzyme
ClinafloxacinCytochrome P450 2C9enzyme
Aripiprazole lauroxilDopamine D2 receptortarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Atarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 2Atarget
Aripiprazole lauroxilCytochrome P450 3A4enzyme
Aripiprazole lauroxilCytochrome P450 2D6enzyme
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Btarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Dtarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Etarget
Aripiprazole lauroxilDopamine D1 receptortarget
Aripiprazole lauroxilDopamine D5 receptortarget
Aripiprazole lauroxilDopamine D3 receptortarget
Aripiprazole lauroxilDopamine D4 receptortarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 2Ctarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 3Atarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 6target
Aripiprazole lauroxil5-hydroxytryptamine receptor 7target
Aripiprazole lauroxilHistamine H1 receptortarget
Aripiprazole lauroxilAlpha-1A adrenergic receptortarget
Aripiprazole lauroxilAlpha-1B adrenergic receptortarget
Aripiprazole lauroxilAlpha-2A adrenergic receptortarget
Aripiprazole lauroxilAlpha-2B adrenergic receptortarget
Aripiprazole lauroxilAlpha-2C adrenergic receptortarget
Aripiprazole lauroxilMuscarinic acetylcholine receptor M1target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M2target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M3target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M4target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M5target
Aripiprazole lauroxilCytochrome P450 3A5enzyme
Aripiprazole lauroxilCytochrome P450 3A7enzyme
Aripiprazole lauroxilSerum albumincarrier
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
5,7-Dichlorokynurenic acidGlutamate receptor ionotropic, NMDA 1target
1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinoneGenome polyproteintarget
2-heptyl-4-hydroxyquinoline N-oxideFumarate reductase flavoprotein subunittarget
2-heptyl-4-hydroxyquinoline N-oxideFumarate reductase iron-sulfur subunittarget
2-heptyl-4-hydroxyquinoline N-oxideFumarate reductase subunit Ctarget
2-heptyl-4-hydroxyquinoline N-oxideFumarate reductase subunit Dtarget
2-heptyl-4-hydroxyquinoline N-oxideFormate dehydrogenase, nitrate-inducible, major subunittarget
2-heptyl-4-hydroxyquinoline N-oxideFormate dehydrogenase, nitrate-inducible, iron-sulfur subunittarget
2-heptyl-4-hydroxyquinoline N-oxideFormate dehydrogenase, nitrate-inducible, cytochrome b556(fdn) subunittarget
2-heptyl-4-hydroxyquinoline N-oxideNapC/NirT cytochrome c family proteintarget
2-heptyl-4-hydroxyquinoline N-oxideCytochrome c nitrite reductase, catalytic subunit NfrA, putativetarget
2-Hydroxyquinoline2-oxo-1,2-dihydroquinoline 8-monooxygenase, oxygenase componenttarget
CasimiroinRibosyldihydronicotinamide dehydrogenase [quinone]target
VazegepantCalcitonin gene-related peptide type 1 receptortarget