- Sulfur Compounds
- Accession Number
Inorganic or organic compounds that contain sulfur as an integral part of the molecule.
- ATC Classification
Drug Drug Description Ademetionine S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... Methionine An amino acid commonly found as a component in total parenteral nutrition. Cystine An oxidated derivative of the amino acid cysteine found in various nutritional products, acne treatments, and creams to treat cervical injury or inflammation. Cysteine An amino acid commonly found as a component of total parenteral nutrition and used as an antidote for acetaminophen overdose. Thiamine A vitamin used to correct vitamin B1 deficiency. Lipoic acid For nutritional supplementation, also for treating dietary shortage or imbalance. Cevimeline A muscarinic agonist with parasympathomimetic activities that is used for the symptomatic treatment of dry mouth in patients with Sjögren's Syndrome. Troglitazone For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise. Sildenafil A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. Dofetilide A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. Ticlopidine A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). Pantoprazole A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. Torasemide A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. Glimepiride A sulfonylurea drug used to treat type 2 diabetes mellitus. Cefotiam A cephalosporin antibiotic used to treat a variety of bacterial infections. Methyclothiazide A diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy. Ziprasidone An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. Dapsone A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis. Calcium acetate A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Cefmenoxime Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria. Cefmetazole A cephalosporin antibiotic used to treat a variety of bacterial infections. Raltitrexed A folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer. Flucloxacillin A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA). Ertapenem A carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. Ibutilide A class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion. Chlorthalidone A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. Ethoxzolamide For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy. Piperacillin A penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam susceptible, β-lactamase generating strains of several bacteria. Omeprazole A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. Metixene Used for the symptomatic treatment of parkinsonism. Aztreonam A beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Sucralfate A gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence. Thiethylperazine A drug used for the treatment of nausea and vomiting. Profenamine An antidyskinetic phenothiazine used to treat the symptoms of Parkinson's disease. Rosiglitazone A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. Pramipexole A non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS). Acetohexamide Used in the management of diabetes mellitus type 2 (adult-onset). Ampicillin A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. Phenoxymethylpenicillin A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. Promazine A phenothiazine used to manage schizophrenia. Cefpiramide For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa. Prochlorperazine A phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. Bendroflumethiazide A diuretic used to suppress lactation and to treat hypertension and edema. Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others. Loracarbef Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,... Lansoprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Cefalotin A broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. Sodium tetradecyl sulfate An anionic surfactant used to treat varicose veins of the lower extremities. Tenoxicam An anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis. Duloxetine A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. Chlorpromazine A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Dicloxacillin A penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug. Cefotaxime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Nitazoxanide A thiazolide anti-infective used to treat infections by protozoa, helminths, anaerobic bacteria, microaerophilic bacteria, and viruses. Triflupromazine Used mainly in the management of psychoses. Also used to control nausea and vomiting. Metolazone A thiazide-like diuretic used to treat hypertension. Tolnaftate An antifungal agent used to treat various skin infections caused by fungi. Rofecoxib A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. Cefdinir A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Zafirlukast A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. Piroxicam An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis. Bosentan A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. Benzthiazide For the treatment of high blood pressure and management of edema. Succimer A mercaptodicarboxylic acid heavy metal chelator used in the treatment of heavy metal poisoning. Cephalexin A first generation cephalosporin used to treat certain susceptible bacterial infections. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Carbenicillin For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria. Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Nizatidine An H2 receptor antagonist used to treat GERD and a variety of ulcers. Cinalukast For Protection against second- phase inflamation in exercise-induced bronchoconstriction and Asthma. Cyclothiazide Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either... Nafcillin A penicillin derivative antibiotic used to treat susceptible staphylococcal infections. Fluphenazine A phenothiazine used to treat patients requiring long-term neuroleptic therapy. Sulfacetamide A corticosteroid used to treat inflammatory ocular conditions and acne vulgaris. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Acamprosate A medication used to maintain alcohol abstinence in patients with alcohol dependence. Sulfametopyrazine An antibiotic used in the treatment or prevention of bacterial infections and malaria. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Cefixime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Chlorpropamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Thioridazine A phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder. Moricizine An antiarrhythmic used to treat arrhythmias. Pentosan polysulfate A sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis. Cephaloglycin For treatment of severe infections caused by susceptible bacteria. Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Amprenavir A protease inhibitor used to treat HIV infection. Methazolamide A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. Tamsulosin An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. Oxacillin A penicillin antibiotic used to treat a number of susceptible bacterial infections. Thiabendazole A benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections. Esomeprazole A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion. Hetacillin Hetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin. Riluzole A glutamate antagonist used to treat amyotrophic lateral sclerosis. Clopidogrel An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body. Methimazole A thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. Malathion A parasympathomimetic organophosphate used to treat head lice. Hydroflumethiazide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. Propiomazine Propiomazine is largely used for its antihistamininc sleep inducing effects in treating insomnia. Sulfasalazine An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. Indapamide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. Meloxicam An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. Sodium lauryl sulfate An anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent. Acetazolamide A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. Disulfiram A carbamate derivative used to treat alcohol addiction. Trifluoperazine A phenothiazine used to treat depression, anxiety, and agitation. Cefaclor A second generation cephalosporin used to treat a wide variety of infections in the body. Tolazamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Cysteamine A cystine depleting agent used to treat the effects of cystinosis. Levamisole Levamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections. Perphenazine A phenothiazine used to treat schizophrenia as well as nausea and vomiting. Penicillamine A chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis. Dorzolamide A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. Flupentixol A thioxanthene neuroleptic used to treat schizophrenia and depression. Eprosartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Chlorothiazide A thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Omapatrilat For the treatment of hypertension. Bumetanide A sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Methdilazine Used for the symptomatic relief of hypersensitivity reactions and particularly for the control of pruritic skin disorders Ceforanide For the treatment of infections caused by susceptible organisms. Famotidine A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. Mesoridazine A phenothiazine antipsychotic used to treat schizophrenia, organic brain disorders, alcoholism, and psychoneuroses. Mezlocillin Used to treat serious gram–negative infections of the lungs, urinary tract, and skin. Azathioprine An immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis. Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. Cyclacillin For the treatment of bacterial infections caused by susceptible organisms. Busulfan An alkylating agent used to treat chronic myelogenous leukemia. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Glyburide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Trichlormethiazide Used in the treatment of oedema (including that associated with heart failure) and hypertension. Probenecid A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia. Mercaptopurine An antineoplastic agent used to treat acute lymphocytic leukemia. Benzylpenicillin A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. Echothiophate An acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma. Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Azlocillin For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae. Acetophenazine For the treatment of disorganized and psychotic thinking. Also used to help treat false perceptions (e.g. hallucinations or delusions.) Cefditoren A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract. Glipizide A sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release. Promethazine A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. Mequitazine For the treatment of Hay fever, urticaria (hives) and allergic rhinitis Dimethyl sulfoxide A reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer. Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Cefuroxime A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. Diazoxide A non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. Gliclazide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Tolbutamide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Bicalutamide An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Pioglitazone A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. Cefapirin A first generation cephalosporin indicated in the treatment of susceptible bacterial infections. Cefadroxil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis. Amifostine A cytoprotective adjuvant used for reduction in the cumulative renal toxicity in patients with ovarian cancer and moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer. Diclofenamide A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. Sulfoxone For the treatment of leprosy and dermatitis herpetiformis Cloxacillin An antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections. Cefprozil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. Sertaconazole A topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients. Amdinocillin Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms. Chlormezanone Used in the management of anxiety and in the treatment of muscle spasm. Brinzolamide A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Ceftriaxone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. Chlorprothixene A thioxanthene antipsychotic. Alimemazine An antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria. Gliquidone A sulfonylurea drug used in the management of diabetes mellitus type 2. Dasatinib A tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Glisoxepide For the treatment of diabetes mellitus type 2. Sulfacytine Used orally in the treatment of acute urinary tract infections. Sulfadoxine A long acting sulfonamide used for the treatment or prevention of malaria. Fosamprenavir An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. Polythiazide A thiazide diuretic used in the management of hypertension and treatment of edema. Quinethazone Used to treat hypertension. Cefamandole A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. Cefazolin A broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract. Cefonicid For the treatment of bacterial infections caused by susceptible microorganisms. Cefoperazone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Cefotetan An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections. Cefoxitin A semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. Ceftizoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea. Cefradine A first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues. Glymidine Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. Methotrimeprazine A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder. Cefepime A fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. Cefacetrile A broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections. Ceftibuten A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis. Cefpodoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis. Diethylthiambutene Not Available Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Imipenem A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. Bacampicillin An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections. Meticillin Used to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as Staphylococcus aureus that would otherwise be resistant to most penicillins. Pivampicillin An ampicillin prodrug used to treat a variety of infections. Pivmecillinam A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs). Tazobactam A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. Ticarcillin A beta lactam antibiotic used to treat a variety of infections in the body. Periciazine A phenothiazine used with other medications to treat aggressiveness, impulsiveness, and hostility associated with psychiatric conditions such as schizophrenia. Acepromazine Acepromazine was first used in humans in the 1950s as an antipsychotic agent. It is now rarely used in humans. Acepromazine is frequently used in animals as a sedative and... Aceprometazine Aceprometazine is often used in combination with meprobamate for the treatment of sleep disorders. Pipotiazine An antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients. Thioproperazine An antipsychotic indicated for the management of acute and chronic schizophrenia, including cases that are refractory to more common neuroleptics. May also be used to treat manic syndromes. Thiothixene An antipsychotic indicated for the management of schizophrenia. Zuclopenthixol An antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance. Etoricoxib A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. SC-74020 Not Available N-Acetylmethionine An amino acid used as a peritoneal dialysis treatment in patients with renal failure and nutritional therapy in patients with nutritional deficiency or post-infection weakness. Dithioerythritol A compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl... Isopropyl beta-D-thiogalactopyranoside A non-metabolizable galactose analog that induces expression of the LAC operon. AR-AO-14418 Not Available WAY-151693 Not Available S-Methylcysteine Not Available L-methionine (R)-S-oxide Not Available 5'-S-methyl-5'-thioadenosine Not Available 2-Aminothiazoline Not Available Selenocysteine A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and... 4-(2-Thienyl)Butyric Acid Not Available 2-Hydroxyethyl Disulfide Not Available Ditiocarb A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM. Latrunculin A Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic... IDD552 Not Available Dansylamide Not Available 3-Butylthiolane 1-Oxide Not Available Tricyclazole Not Available Methylthioinosine An analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position. Piretanide A loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin. 5-(2-hydroxyethyl)-4-methylthiazole Not Available GE-2270A Not Available p-Toluenesulfonic acid Not Available 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid Not Available N,O-Didansyl-L-Tyrosine Not Available RWJ-51084 Not Available Thiocellobiose Not Available N-cyclohexyltaurine Not Available Cephalosporin C Not Available S-Phosphocysteine Not Available Isopenicillin N Not Available Ethanesulfonic acid Not Available Tribenuron Methyl Not Available P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid Not Available Dihydrolipoic Acid Not Available Trifluoromethionine Not Available Batimastat Not Available D-pantetheine 4'-phosphate Not Available Dodecyl sulfate Not Available Butyrylthiocholine A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem] Monastrol Not Available Taurocholic acid The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats... S-sulphocysteine Not Available Thiodigalactoside Thiodigalactoside is a solid. This compound belongs to the dihexoses. These are disaccharides containing two hexose carbohydrates. This medication is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core... N-Formylmethionine N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well... N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide Not Available Latamoxef Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,... Naphthalene-2,6-disulfonic acid Not Available Hydroxyfasudil Not Available Myxothiazol Not Available Nimesulide A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. Suramin For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms. Tanaproget Tanaproget (NSP-989) is an investigational non-steroidal progestin. It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most... Thenoyltrifluoroacetone Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration. THIO-ATPA Not Available 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Not Available Tienilic acid For the treatment of hypertension. Febuxostat A xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol. Lintitript For the treatment of pancreatic cancer and appetite disorders. Ceftobiprole A cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria. Lucanthone Intended for use as a radiation sensitizer in the treatment of brain cancer. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). Erdosteine A mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD). INCB13739 Investigated for use/treatment in diabetes mellitus type 2 and diabetes prevention. SLV319 Investigated for use/treatment in obesity. Cimicoxib Investigated for use/treatment in depression. NGX267 Investigated for use/treatment in alzheimer's disease and schizophrenia and schizoaffective disorders. PTC299 Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors. KD3010 Investigated for use/treatment in metabolic disease and obesity. CYC116 Advanced solid tumors REP8839 For the treatment of bacterial infections caused by susceptible microorganisms (Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), and Streptococcus pyogenes). XL765 For the treatment of various forms of cancer. Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Rotigotine A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. Tetomilast Investigated for use/treatment in ulcerative colitis. Dexlansoprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Actelion-1 Investigated for use/treatment in cardiovascular disorders, hypertension, and pulmonary hypertension. Chlorfenson Investigated for use/treatment in fungal infections. PRO 2000 Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection. TBC-3711 Investigated for use/treatment in congestive heart failure, hypertension, and pulmonary hypertension. Cardarine Investigated for use/treatment in hyperlipidemia. NOX-700 Investigated for use/treatment in diabetes mellitus (type 2). Custirsen Investigated for use/treatment in brain cancer and breast cancer. AMG-131 Investigated for use/treatment in diabetes mellitus type 2. KW-7158 Investigated for use/treatment in urinary incontinence. Naluzotan Investigated for use/treatment in anxiety disorders and depression. PRX-08066 Investigated for use/treatment in chronic obstructive pulmonary disease (COPD) and pulmonary hypertension. Faropenem medoxomil Investigated for use/treatment in bacterial infection, bronchitis, otitis media, and pediatric indications. BL-1020 Investigated for use/treatment in schizophrenia and schizoaffective disorders. Trabedersen Investigated for use/treatment in brain cancer, colorectal cancer, melanoma, and pancreatic cancer. Elesclomol Investigated for use/treatment in melanoma. Cefilavancin Investigated for use/treatment in bacterial infection, skin infections/disorders, and staph bacterial infections. Alethine Investigated for use/treatment in blood (blood forming organ disorders, unspecified), lymphoma (unspecified), and multiple myeloma. Laromustine Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), colorectal cancer, leukemia (lymphoid), leukemia (myeloid), lung cancer, myelodysplastic syndrome, pediatric indications, and solid tumors. CLX-0921 Investigated for use/treatment in diabetes mellitus type 2. Ciluprevir Investigated for use/treatment in hepatitis (viral, C). OSI-930 Investigated for use/treatment in solid tumors. Edonerpic Investigated for use/treatment in alzheimer's disease. Resatorvid Investigated for use/treatment in sepsis and septicemia. Varlitinib Investigated for use/treatment in cancer/tumors (unspecified). SNS-032 Investigated for use/treatment in cancer/tumors (unspecified), leukemia (unspecified), lymphoma (unspecified), multiple myeloma, and solid tumors. Filanesib Investigated for use/treatment in cancer/tumors (unspecified). SNS-314 Investigated for use/treatment in solid tumors. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Sulfadimethoxine For use in the treatment of infections. Acetylcysteine A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. Pizotifen A serotonin and tryptamine antagonist indicated for migraine prophylaxis. Prasugrel A P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI. Doripenem An antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. Rivaroxaban A factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations. Caldaret Investigated for use/treatment in heart disease and myocardial infarction. Arzoxifene Investigated for use/treatment in breast cancer, osteoporosis, and endometrial cancer. Udenafil A PDE5 inhibitor used to treat erectile dysfunction. Sitaxentan Investigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure. Simeprevir A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. Refametinib Investigated for use/treatment in cancer/tumors (unspecified). Elinogrel Investigated for use/treatment in cardiovascular disorders and myocardial infarction. Relacatib Investigated for use/treatment in osteoporosis and bone metastases. Indisulam Investigated for use/treatment in lung cancer. Abafungin Investigated for use/treatment in fungal infections, bacterial infection, skin infections/disorders, and onychomycosis. Ravuconazole Investigated for use/treatment in fungal infections, aspergillosis, candidiasis, and onychomycosis. Avasimibe Investigated for use/treatment in peripheral vascular disease. Aprinocarsen Investigated for use/treatment in lung cancer. Cariporide Investigated for use/treatment in cardiac surgery. Clomethiazole Investigated for use/treatment in strokes. Repinotan Investigated for use/treatment in strokes, cerebral ischemia, and depression. Ertiprotafib Investigated for use/treatment in diabetes mellitus type 2. Tramiprosate Investigated for use/treatment in strokes and alzheimer's disease. Tesaglitazar Investigated for use/treatment in diabetes mellitus type 2. Pazopanib An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy. Ceftaroline fosamil An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. N-chlorotaurine Investigated for use/treatment in eye disorders/infections. Clazosentan Investigated for use/treatment in strokes. Lornoxicam An NSAID indicated in the treatment of mild to moderate pain, as well as rheumatoid arthritis and osteoarthritis. Sulfaphenazole For the treatment bacterial infections. Zaltoprofen A non-steroidal anti-inflammatory drug approved for use in Japan in 1993. Manganese A transition metal used for supplementation of manganese during Total Parenteral Nutrition (TPN). Fomivirsen Indicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428]. Cupric sulfate A compound used as an intravenous copper supplement for Total Parenteral Nutrition (TPN). Dimercaprol A chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium. Mafenide An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Tiopronin A thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria. TO-901317 TO-901317 is an LXRalpha and LXRbeta agonist. 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Not Available 4,4'-DIPYRIDYL DISULFIDE Not Available 5-(2-methylpiperazine-1-sulfonyl)isoquinoline Not Available Latrunculin B Latrunculin B is a 14-membered macrolide attached to 2-thiazolidinone moiety, isolated from Red Sea sponge Latrunculia magnifica. IDD594 Not Available 11-MERCAPTOUNDECANOIC ACID Not Available 2-Naphthalenesulfonic acid Not Available Sulthiame A carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies. Thiorphan A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms. 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID Not Available 4-(2-AMINOETHYL)BENZENESULFONAMIDE Not Available Azidocillin For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including... Pipazethate For the treatment of cough. Sulfamoxole For the treatment of bacterial infection. Isothipendyl A 1st generation histamine H1 antagonist primarily applied topically as an antipruritic. Metiamide Potential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion. Lurasidone An atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder. Taurochenodeoxycholic acid Taurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy. Tauroursodeoxycholic acid The taurine conjugate of ursodeoxycholic acid with antiapoptotic and ER stress response dampening effects used in some countries to treat gallstones. It is also being investigated for a wide variety of other conditions. Temocapril Temocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction). Vemurafenib A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. Mirabegron A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity. Canagliflozin A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM. Aleglitazar Investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity. Perospirone For the treatment of schizophrenia and acute cases of bipolar mania. Acediasulfone Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone. Macitentan An endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression. Letosteine Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions. Isoxicam Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States. Azosemide Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. Glibornuride Glibornuride is a sulfonylurea-type anti-diabetic drug. Fursultiamine Compound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative. Dimetotiazine Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions. Cyamemazine Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an... Cefaloridine Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH. Articaine A local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures. Ceftolozane A cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia. Blinatumomab An antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). Cefminox Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan. Ceritinib An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. Cobicistat A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. Edoxaban A novel oral anticoagulant used for reducing the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF). Potassium alum Potassium alum is considered safe by the FDA and its use is in homepathic or OTC products. Due to its presence in several different drugs, the main indications for the... Coenzyme M A uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract. Brexpiprazole A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct and schizophrenia. Trypan blue free acid A dye used as a visualizing aid to stain the epiretinal membranes during ophthalmic surgical vitrectomy procedures, thereby facilitating removal of the tissue. Dosulepin A tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential. Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Talsupram Talsupram is a selective norepinephrine reuptake inhibitor (NRI). It was under research for the treatment of depression in 1960 and 1970 but it was never marketed. Talsupram presents a similar... Lobeglitazone Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use... Netoglitazone Netoglitazone (MCC-555) is a hypoglycemic agent. Rivoglitazone Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co. Ciglitazone Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class. Ciglitazone was never used as a medication, but it sparked interest in... Firocoxib Used for the treatment of pain inflammation and fever in horses and dogs. Zotepine Zotepine, like other atypical antipsychotics, is considered as the first-line treatment in newly diagnosed schizophrenia. It is usually thought to be an option of choice for managing acute schizophrenic episodes... Methylene blue An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia. Strontium ranelate A medication used for the management of severe osteoporosis in high-risk postmenopausal women and adult men. Sodium aurothiomalate A disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis. Tianeptine An atypical tricyclic antidepressant with antidepressant and anxiolytic effects primarily used to treat major depressive disorder. Carindacillin A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA. Procaine benzylpenicillin A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Zinc sulfate A drug used to replenish low levels of zinc or prevent zinc deficiency, or to test for zinc deficiency. Sulbactam An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Sulfabenzamide A sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA. Technetium Tc-99m sulfur colloid A radiopharmaceutical diagnostic agent used for the localization of lymph nodes, evaluation of peritoneovenous (LeVeen) shunt patency, imaging areas of functioning reticuloendothelial cells, and gastrointestinal imaging. Sodium sulfate An agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination. Thiosulfuric acid A sulfur donor used for sequential use with sodium nitrite for the reversal of acute cyanide poisoning that is judged to be life-threatening. Ecamsule A sunscreen agent found in sunscreens that absorbs UV rays. Sulfur hexafluoride A medication used in ultrasound to enhance viewing of blood vessels and the urinary tract. Ensulizole An ingredient used in sunscreens to absorb UVB radiation. Selenomethionine Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can... Barium sulfate A contrast agent used for CT scans of the gastrointestinal tract. Pyrantel An anthelmintic used to treat helminth infections. Sodium sulfide Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes... Light green SF yellowish Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in... Pantethine A naturally occurring compound derived from panthothenic acid. It acts as an intermediate in endogenous coenzyme A synthesis and is used as a dietary supplement to treat hypertriglyceridemia. Calcium sulfide Not Annotated Aluminum sulfate A medication used to prevent infections and to treat minor bleeding. Sulfuric acid Not Annotated Pidotimod A synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections. Cefroxadine Was used for the treatment of bacterial infections. Cefalonium Not Annotated Clorsulon Not Annotated Coumaphos This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a... Cythioate Cythioate is a member of the organothiophosphate compounds that is used as an insecticide and anthelmintic. It is mainly used in veterinary as a treatment for fleas. Deracoxib Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to... Famphur Not Annotated Fenthion Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is... Phenothiazine Phenothiazine (PTZ) is an organic thiazine compound. Phosmet Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals,... Ronnel Not Annotated Sulfachlorpyridazine A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. Sulfaethoxypyridazine Not Annotated Sulfanitran Not Annotated Sulfaquinoxaline Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K... Tioxidazole Not Annotated Xylazine Xylazine is a clonidine analog which acts as an agonist at α2 adrenoceptors. Veterinarians also use xylazine as an emetic, especially in cats. Ceftiofur Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active... 2-mercaptobenzothiazole Not Annotated Sulfotep Not Annotated Cefovecin Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. It is the first single-dose injectable antibiotic for dogs and cats that assures owner... Dithiazanine Not Annotated Masitinib Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the... Propiopromazine Not Annotated Tiletamine This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt... Lesinurad A uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy. Venetoclax A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. Asunaprevir An NS3 protease inhibitor used to treat hepatitis C genotype 1b. Nitrocefin Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin... Lifitegrast A medication used to treat dry eye disease. PF-4191834 PF-4191834 has been investigated for the basic science of Asthma. Afuresertib Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic. Pictilisib Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others. Treosulfan Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood. Pavinetant Pavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia. Racecadotril An anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea. Ipragliflozin Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. Encorafenib A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations. Mitoglitazone Mitoglitazone has been used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease. GSK-2330672 GSK2330672 has been investigated for the treatment of Diabetes Mellitus, Type 2. Vonoprazan A potassium-competitive acid blocker used in the treatment of erosive diseases of the digestive tract, including reflux esophagitis and duodenal ulcers. Benfotiamine A derivative of thiamine thought to be useful in the management of diabetic neuropathy, although evidence is lacking. Tenapanor An NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). Zytron Zytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic). DMPA has been investigated for the... Pilaralisib Pilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors,... BMS-903452 BMS-903452 has been used in trials studying the treatment of Diabetes. Danoprevir Danoprevir has been used in trials studying the treatment of Hepatitis C, Chronic. Allicin Allicin has been used in trials studying the treatment of Follicular Lymphoma. Mirodenafil Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction. AZD-5672 Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis. Faldaprevir Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. Baricitinib A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. Nifurtimox An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). TMC-647055 TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus. PF-04958242 PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural. Pritelivir Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes. Litronesib Litronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others. Alvelestat Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease. PF-00610355 PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others. Avagacestat Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease. Efatutazone Efatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others. 2,4-thiazolidinedione Thiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2. Gisadenafil Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia. Danirixin Danirixin has been used in trials studying the treatment and basic science of Virus Diseases, Nutritional Status, Pulmonary Disease, Chronic Obstructive, and Infections, Respiratory Syncytial Virus. Flomoxef Flomoxef has been used in trials studying the treatment of Urinary Tract Infection. Triapine Triapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others. Tasisulam Tasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others. Teneligliptin Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus. Lomibuvir Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection. Ilaprazole Ilaprazole has been investigated in Helicobacter Infections. Letaxaban Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome. Avatrombopag A thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease who are scheduled to undergo a procedure. Alpelisib Alpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer.[Label] This cancer must be hormone receptor (HR)-positive, human epidermal growth factor... Ponesimod A sphingosine 1-phosphate receptor modulator indicated to treat relapsing multiple sclerosis. Ibodutant Ibodutant has been used in trials studying the treatment of Irritable Bowel Syndrome and Irritable Bowel Syndrome With Diarrhea. Setrobuvir Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic. MK-0767 MK0767 has been used in trials studying the treatment of Dyslipidemia, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Diabetes Mellitus, Type II, among others. Radalbuvir Radalbuvir has been used in trials studying the treatment of Chronic Hepatitis C, Chronic HCV Infection, and Chronic Hepatitis C Infection. T-900607 T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer. LCL-161 LCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others. CPI-613 CPI-613 has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others. Sultamicillin A mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria. Tideglusib Tideglusib was initially formulated for the treatment of Alzheimer and progressive supranuclear palsy. The raising interest for the use of tideglusib comes from the significant upregulation of GSK-3 in the... Elubrixin Elubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease (COPD). GSK-256066 Gsk256066 has been used in trials studying the treatment and diagnostic of SAR, Asthma, Mild Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis, among others. Rigosertib Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others. S-3304 S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non... Bucillamine Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis. Presatovir Presatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections. Dalcetrapib Dalcetrapib is under investigation for the treatment of Acute Coronary Syndrome. Faropenem Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia. Auriclosene Auriclosene has been used in trials studying the treatment of Impetigo, Bacterial Conjunctivitis, Asymptomatic Bacteriuria, and Adenoviral Conjunctivitis. Tozadenant Tozadenant has been investigated for the basic science of Cocaine Dependence. Oxothiazolidinecarboxylic acid Procysteine has been used in trials studying the treatment of HIV Infections. Cerlapirdine Cerlapirdine has been investigated for the treatment of Alzheimer Disease. Temefos Diphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria. Iguratimod Iguratimod is under investigation in Rheumatoid Arthritis. GW-274150 GW274150 has been used in trials studying the treatment and prevention of Asthma, Migraine, Migraine Disorders, and Arthritis, Rheumatoid. AZD-7762 AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies. ABT-751 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. CRS-3123 CRS3123 has been used in trials studying the treatment of Clostridial Infection and Clostridium Difficile Colitis. Begacestat Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease. Vidupiprant Vidupiprant has been used in trials studying the treatment and basic science of Asthma. Navitoclax Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is... Temocillin Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. MBX-2982 MBX-2982 has been used in trials studying the treatment of Diabetes. CG-400549 CG400549 has been used in trials studying the treatment of Skin Infection. 5-amino-1,3,4-thiadiazole-2-thiol ATT has been investigated in Pulmonary Tuberculosis. Imrecoxib Imrecoxib has been used in trials studying the treatment of Knee Osteoarthritis. Apricoxib Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others. R-306465 R306465 has been used in trials studying the treatment of Neoplasms. Sagopilone Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is... Resminostat Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others. Polmacoxib Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee. Voxtalisib Voxtalisib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Breast Cancer, among others. Saccharin A non-nutritive artificial sweetener for sweetening foods and drinks. Sulforaphane Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli. Bitopertin Bitopertin has been used in trials studying the treatment of Schizophrenia and Obsessive-Compulsive Disorder. Taurolidine An antimicrobial derivative of taurine used for prophylaxis of catheter-related infections. Acotiamide Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia. Elobixibat Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. Fasiglifam Fasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes Mellitus, and Diabetes Mellitus, Type 2. Alagebrium Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity, Diabetic Nephropathy, and Cardiovascular Disease, among others. Fedratinib Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk. E-7820 E7820 has been investigated for the treatment of Colon Cancer and Rectal Cancer. GSK-356278 Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington Disease, Depressive Disorder, Huntingtons Disease, and Depressive Disorder, Major, among others. MK-5108 MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors. Razupenem Razupenem has been used in trials studying the treatment of Skin Infections. Indiplon Indiplon has been used in trials studying the treatment of Insomnia and Depression. Reparixin Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type 1, and Pancreatic... Taprenepag Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. Ibipinabant Ibipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes. Intepirdine Intepirdine has been used in trials studying the treatment of Alzheimer's Disease. Phenethyl Isothiocyanate Phenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders. Methylselenocysteine Methylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease. Omipalisib Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis. Perazine A phenothiazine antipsychotic used in the acute and chronic treatment of psychotic disorders. Mibampator Mibampator has been used in trials studying the treatment of Alzheimer's Disease. ASP-3026 ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS. TAK-901 TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others. Pelitrexol Pelitrexol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Balaglitazone Balaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2. CMX-2043 CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. CHF-6001 CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease. Ataciguat Ataciguat has been investigated for the basic science of Aortic Valve Stenosis. Amithiozone Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection. Grapiprant The effects of grapiprant have been investigated in the area of analgesia and anti-inflammation due to the effects that have been reported about this molecule. This molecule has been approved... MK-0752 Mk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer). Sivelestat Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult. Buthionine sulfoximine Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin). Chlorsulfaquinoxaline Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer. Prothipendyl A neuroleptic agent indicated in the treatment of restlessness and agitation in patients with underlying psychiatric conditions. CP-547632 CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others. Roniciclib Roniciclib has been investigated for the treatment of Small Cell Lung Carcinoma. Nepicastat Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder. Tinoridine Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults). LFF-571 LFF571 has been used in trials studying the treatment of Moderate Clostridium Difficile Infection. Biapenem A carbapenem antibiotic indicated in the treatment of bacterial infections. Ramatroban Ramatroban has been used in trials studying the treatment of Asthma. Fenoverine A phenothiazine based anti-spasmodic agent indicated in the treatment of irritable bowel syndrome. CH-5132799 CH5132799 has been used in trials studying the treatment of Solid Tumors. Upamostat Upamostat has been used in trials studying the treatment of Pancreatic Cancer. Methanesulfonyl Fluoride Methanesulfonyl Fluoride has been used in trials studying the treatment of Safety. LY-2811376 LY2811376 has been used in trials studying the basic science of Alzheimer's Disease. Talarozole Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation. QGC-001 QGC001 has been used in trials studying the treatment of Essential Hypertension. Deferitazole Deferitazole has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red Blood... AGN-201904 Agn 201904 has been used in trials studying the prevention of Peptic Ulcer. Ripasudil A rho kinase inhibitor indicated to treat ocular hypertension and open-angle glaucoma. Butaperazine Butaperazine was approved in 1967 , and possibly discontinued in the 1980s . Fentiazac Not Annotated Stibophen Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms. Thiram Thiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for... Phthalylsulfathiazole A sulfonamide antibacterial indicated in the treatment of gastrointestinal infections. Tropatepine Tropatepine has been used in France for its antiparkinsons activities . Clothiapine An atypical antipsychotic indicated in the treatment of acute psychosis, exacerbations of chronic psychosis, chronic psychosis, paranoid psychosis, and anxiety. Penimepicycline Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification... Cefatrizine Not Annotated Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Pimethixene Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis. Epicillin Not Annotated Methiodal Not Annotated Mannosulfan Not Annotated Mesulfen Not Annotated Tolciclate Not Annotated Chlorproethazine Not Annotated Mefruside Not Annotated Carbutamide Not Annotated Sulbutiamine A thiamine derivative indicated in the treatment of asthenia. Thiazinam Not Annotated Mebutizide Not Annotated Citiolone Not Annotated Mazaticol Not Annotated Cefodizime A broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria. Antimony pentasulfide Not Annotated Sodium apolate Not Annotated Etamsylate A hemostatic agent that acts by restoring capillary resistance and improving platelet adhesion. Cefsulodin Not Annotated Cefetamet Not Annotated Carfecillin Not Annotated Dobesilic acid A medication indicated in the treatment of hemorrhoids, venous insufficiency, and other microangiopathies. Cyclopenthiazide Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients... Sulfatolamide Not Annotated Carumonam Not Annotated Thiopropazate Not Annotated Succinylsulfathiazole Not Annotated Ticlatone Not Annotated Clorexolone Not Annotated Cefbuperazone Not Annotated Metisazone Not Annotated Ethacizine Not Annotated Propicillin Not Annotated Niridazole Not Annotated Cefozopran Not Annotated Oxantel An antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections. Metahexamide Not Annotated Cefpirome An antibiotic indicated in the treatment of a wide variety of infections in the body. Sulbenicillin Not Annotated Sulfathiourea Not Annotated Dixanthogen Not Annotated Sulfaguanidine Not Annotated Penamecillin Not Annotated Dexrabeprazole A proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers. Aurotioprol Not Annotated Sulfamethoxypyridazine A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis. Tertatolol Tertatolol is a beta blocker. Cefazedone Not Annotated Dixyrazine Not Annotated Clopamide Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure. Xipamide A diuretic indicated in the treatment of edema. Oblimersen Not Annotated Talampicillin Not Annotated Aspoxicillin Not Annotated Oxomemazine A phenothiazine derivative antihistamine indicated in the treatment of allergies. Ceftezole Not Annotated Metampicillin Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the... Noxytiolin Local antibacterial that probably acts by releasing formaldehyde in aqueous solutions. It is used for THERAPEUTIC IRRIGATION of infected body cavities - bladder, peritoneum, etc. and as a spray for... Clopenthixol Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Anethole trithione A medication used to treat dry mouth associated with medication or radiotherapy of the head and neck. Dimazole Dimazole (diamthazole) is an antifungal. It was withdrawn in Franch in 1972 due to neuropsychiatric reactions. Ferric subsulfate Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin... Racemethionine A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers. SB-269970 SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist... SR-9009 SR-9009 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the... SR-9011 SR-9011 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the... Sodium bisulfite An ingredient in parenteral nutrition products for patients with severe liver disorders. Thiosalicylic acid Not Annotated Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... Darglitazone Not Annotated Englitazone Englitazone is a hypoglycemic agent. SC-236 SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . NS-398 NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. Hycanthone Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used. Dimethyl sulfone Not Annotated Methionine sulfoximine Not Annotated 7-Aminodesacetoxycephalosporanic acid Not Annotated Pyrithione An antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis. Tetramethylthiuram monosulfide Not Annotated Zinc dibutyldithiocarbamate Zinc dibutyldithiocarbamate is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6... Thiohexam Thiohexam is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... 2,2'-Dibenzothiazyl disulfide 2,2'-Dibenzothiazyl disulfide is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6... Morpholinylmercaptobenzothiazole Not Annotated Acetylcysteine amide Not Available Potassium sulfate An osmotic laxative used to cleanse the colon before a colonoscopy. Eprodisate Investigated for use/treatment in amyloidosis. Perphenazine enanthate Not Annotated Phenyl hydrogen sulfate Not Annotated Estradiol sulfamate Investigated for use/treatment in endometriosis. Piprozolin Not Annotated Tosylchloramide A chlorinated disinfectant of the genitals and injured skin. S-adenosyl-L-homocysteine 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions. Taurine An ingredient found in mixture products indicated for nutritional support. Cocarboxylase The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. S-Ethylisothiourea S-Ethylisothiourea is a nitric oxide synthase inhibitor. Irosustat Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer. Benzenesulfinic acid Not Available Nesbuvir Nesbuvir has been investigated for the treatment of Hepatitis C. Fasudil Fasudil has been investigated in Carotid Stenosis. Encenicline Encenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases. Vosaroxin Vosaroxin is under investigation for the treatment of Leukemia, Myeloid, Acute. Quizartinib Quizartinib is under investigation in Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies. It is a potent inhibitor of FLT3. Cefamandole nafate A second generation cephalosporin indicated in the prevention of infections during surgery. PX-12 Investigated for use/treatment in cancer/tumors (unspecified), gastric cancer, and pancreatic cancer. Ceftobiprole medocaril A cephalosporin indicated in the treatment of pneumonia. Mercaptoethanol Not Available Narlaprevir Not Annotated Macozinone Macozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169). SB-649868 SB-649868 is under investigation in clinical trial NCT01030939 (Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers). Methamidophos Methamidophos is under investigation in clinical trial NCT03223753 (Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia in First Remission). BMS-791826 BMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males). ABT-639 ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain). Flutemetamol Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning). Aprocitentan Aprocitentan is under investigation in clinical trial NCT03541174 (A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and... Dexpramipexole Dexpramipexole is under investigation in clinical trial NCT01511029 (Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of... Pittsburgh Compound B Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD). Dubermatinib Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL). JNJ-26489112 JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy). Esaxerenone Esaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension). Telaglenastat Telaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors). Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone is under investigation in clinical trial NCT02688101 (Dose-finding and Pharmacokinetic Study of DpC, Administered Orally to Patients With Advanced Solid Tumors). Vercirnon Vercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. It is... Epalrestat Epalrestat is under investigation in clinical trial NCT03244358 (Evaluation of Epalrestat in Metastatic Triple-negative Breast Cancer). Florasulam Florasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station). VM4-037 VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037). Xanomeline Xanomeline is under investigation in clinical trial NCT02831231 (Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium). MK-2748 MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)). SAR-125844 SAR-125844 is under investigation in clinical trial NCT01391533 (Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors). GLPG-0974 GLPG-0974 is under investigation in clinical trial NCT01721980 (Multiple Ascending Dose Study of GLPG0974 in Healthy Subjects). Giripladib Giripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee). Thioglycolic acid Thioglycolic acid is under investigation in clinical trial NCT03238105 (Treatment of Periorbicular Hyperchromia Comparing 10% Thioglycolic Acid Peeling Versus Pulsed Intense Light). Glucoraphanin Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]). Timolol A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Tolevamer A potassium-binding resin used in the treatment of hyperkalemia. Edaglitazone Investigated for use/treatment in diabetes mellitus type 2. Flutemetamol (18F) A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment. Ruzasvir Ruzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection. Epacadostat Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others. PF-00489791 PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic Nephropathies, Hypertension, Pulmonary, and Peripheral Vascular Disease. Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Emeramide Emeramide has been used in trials studying the treatment of Mercury Poisoning. Defactinib Defactinib has been investigated for the treatment of Malignant Pleural Mesothelioma. Verubecestat Verubecestat is under investigation for the treatment of Alzheimer's Disease, Prodromal Alzheimer's disease, and Amnestic Mild Cognitive Impairment. Verubecestat is Merck’s investigational oral β-site amyloid precursor protein cleaving enzyme (BACE1... GLPG-0187 GLPG0187 has been used in trials studying the treatment of Solid Tumors. Lefamulin A pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP). Lusutrombopag A medication used to treat thrombocytopenia in patients with chronic liver disease scheduled to have a procedure. Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Volixibat Volixibat is an investigational drug that has not been approved for use in any conditions. Baloxavir marboxil A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza. Methylchloroisothiazolinone Methylchloroisothiazolinone is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... LGD-6972 LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus). Lanifibranor Lanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337). PF-05089771 PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). Cefiderocol A cephalosporin antibiotic used in complicated urinary tract infections. Oliceridine A biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists. Ceralasertib Ceralasertib is under investigation in clinical trial NCT03682289 (Phase II Trial of AZD6738 Alone and in Combination With Olaparib). TAK-243 TAK-243 is under investigation in clinical trial NCT03816319 (TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia). Rogaratinib Rogaratinib is under investigation in clinical trial NCT03762122 (Rogaratinib in Patients With Advanced Pretreated Squamous-cell Non-small Cell Lung Cancer (SQCLC)). ABT-072 ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat... ONO-8539 ONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease). Cerdulatinib Cerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)). Calcium sulfate Not Annotated JE-2147 Not Available 1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone Not Available 5'-Guanosine-Diphosphate-Monothiophosphate Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation,... 2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamide Not Available 2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide Not Available Deacetoxycephalosporin C Not Available Thiocitrulline Not Available 2-Pyridinethiol Not Available Acid yellow 54 free acid Not Available N-Acetyl-glucosamine thiazoline N-Acetyl-glucosamine thiazoline (NAG-thiazoline) is an analog of the oxazolinium bicyclic intermediate leading from N-acetylglucosamine to 1,6-anhydro-N-acetylmuramic acid. PLX-4720 Not Available GW-590735 Not Available GW-813893 Not Available CGS-27023 Not Available H-89 Not Available Zopolrestat Not Available Lidorestat Not Available SKF-91488 Not Available CP-94707 Not Available Thiacloprid Not Available Hexadecanesulfonyl fluoride Not Available 3-(cyclohexylamino)propanesulfonic acid Not Available 1-Naphthylamine-5-sulfonic acid Not Available 4-methylthio-2-oxobutanoic acid Not Available Cysteine-S-acetamide Not Available Benzylsulfonic acid Not Available 2-(N-morpholino)ethanesulfonic acid Not Available S-Benzylcysteine Not Available N-phenylthiourea Not Available L-methionine sulfone Not Available Vinylsulfonic acid Not Available Homocysteine Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine. 8-anilinonaphthalene-1-sulfonic acid Not Available Ritonavir An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. Fasitibant Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee). Fezolinetant Fezolinetant is under investigation in clinical trial NCT04234204 (A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women in Asia Going Through Menopause). Baloxavir Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)). (Rp)-cAMPS Not Available Sulbactam pivoxil A prodrug of a beta-lactamase inhibitor used to improve the efficacy of beta lactam antibiotics Desmeninol An amino acid derivative indicated in the management of balanced protein metabolism in patients with renal dysfunction. Potassium metabisulfite Not Annotated Sodium metabisulfite An ingredient used in products to treat dehydration and replace electrolytes. Buthiazide A diuretic indicated in the treatment of edema caused by congestive heart failure, as well as hepatic and renal diseases. Piroxicam cinnamate An anti-inflammatory drug indicated to treat pain and inflammation. Methylisothiazolinone Not Annotated Carbocisteine A expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity. Thiamine disulfide A B-vitamin indicated to treat neurological conditions caused by B vitamin deficiency. Thioctamide An ingredient in nutritional products for liver health. 2,3-Dimercapto-1-propanesulfonic acid Not Annotated Clorotepine Not Annotated Gold sodium thiosulfate Not Annotated Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Parathiazine Not Annotated Garlic oil Not Annotated Monophosphothiamine A B vitamin for supplementation to treat macrocytic anemia, and other conditions caused by B vitamin deficiencies. Azemiglitazone Azemiglitazone is under investigation in clinical trial NCT01280695 (A Randomized, Double-blind, Comparator- and Placebo-controlled, Multiple-dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in... PLX8394 PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors). DU125530 DU125530 is under investigation in clinical trial NCT01119430 (Fluoxetine Versus Fluoxetine Plus DU125530 in Major Depressive Disorder). SP-420 SP-420 is under investigation in clinical trial NCT03801889 (SP-420 in Subjects With Transfusion-dependent Beta-thalassemia or Other Rare Anemias). APG-1387 APG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B). Batabulin Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients). TAK-715 TAK-715 is under investigation in clinical trial NCT00760864 (Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis). HIV Integrase Inhibitor HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects). Capadenoson Capadenoson is under investigation in clinical trial NCT00518921 (Capadenoson in Angina Pectoris). Deferitrin Deferitrin is under investigation in clinical trial NCT00069862 (Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-thalassemia). Firsocostat Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)). Ladarixin Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function). Mitapivat Mitapivat is under investigation in clinical trial NCT03548220 (A Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)). Tropifexor Tropifexor is under investigation in clinical trial NCT02516605 (A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients). Vicagrel Vicagrel is under investigation in clinical trial NCT03599284 (The Efficacy, Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel). Razuprotafib Razuprotafib, also known as AKB-9778, is a small-molecule inhibitor restoring Tie2 activation by inhibiting VE-PTP.[L27171,L27176] In investigations against diabetes and COVID-19, razuprotafib is self-administered by patients through subcutaneous injection. Sulfur dioxide Not Annotated Benzoyloxymethylthiamine Not Annotated Tetramisole An anthelmintic indicated to treat hookworm infections. Ketotifen A histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis.
- Drugs & Drug Targets