Picropodophyllin

DB12802InvestigationalSmall molecule

Picropodophyllin has been investigated for the treatment of Non Small Cell Lung Cancer.

Mechanism: Pharmacologically active on Insulin-like growth factor 1 receptor
Curator reviewed
Formula / weight: C₂₂H₂₂O₈ · 414.41 g/mol (avg)
Code names: AXL1717

Resolves to

Compound

Structure

InChIKeyYJGVMLPVUAXIQN-HAEOHBJNSA-NSMILESCOC1=CC(=CC(OC)=C1OC)[C@H]1[C@H]2[C@H](COC2=O)[C@@H](O)C2=CC3=C(OCO3)C=C12

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Picropodophyllin, and which of those have an active Phase 3 trial?

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