Accession Number

Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.

DrugDrug Description
AdapaleneA third-generation topical retinoid with anti-comedogenic, comedolytic, and anti-inflammatory properties used to treat acne vulgaris in adolescents and adults.
TolnaftateAn antifungal agent used to treat various skin infections caused by fungi.
PropranololA non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
SimvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
PhylloquinoneA fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses.
SertralineA selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
BunaftineNot Annotated
TerbinafineAn allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
CarbarylA medication used in shampoo to remove lice.
DexpropranololNot Available
Naphthalene-2,6-disulfonic acidNot Available
PRO 2000Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection.
1-Naphthylamine-5-sulfonic acidNot Available
2-Naphthalenesulfonic acidNot Available
MenadioneThe primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification.
BexaroteneA retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
AtovaquoneAn antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
PodofiloxA topical agent used for the treatment of external genital warts and perianal warts.
DezocineIndicated in the treatment of moderate to severe pain.
LevobunololA beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
MibefradilFor the treatment of angina and high blood pressure.
Nanaomycin DNot Available
1-naphthaleneacetic acidA drug used to treat digestive problems from excessive fat consumption and functional disorders of the gallbladder and bile ducts.
LG-100268LG-100268 is a retinoid X receptor (RXR) selective compound.
FlaviolinNot Available
DansylamideNot Available
N,O-didansyl-L-tyrosineNot Available
Mevinolinic acidNot Available
8-anilinonaphthalene-1-sulfonic acidNot Available
LawsoneNot Available
SuraminFor treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
TamibaroteneInvestigated for use/treatment in leukemia (unspecified).
RotigotineA non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome.
AmibegronInvestigated for use/treatment in depression, irritable bowel syndrome (IBS), and obesity.
LasofoxifeneInvestigated for use/treatment in postmenopausal osteoporosis to reduce the risk of both vertebral and novertebral fractures, as well as address other postmenopausal conditions, including reduction in risk of breast cancer...
ElacestrantAn estrogen receptor antagonist used to treat ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.
NaproxcinodInvestigated for use/treatment in pain (acute or chronic), inflammatory disorders (unspecified), osteoarthritis, and arthritis and arthritic pain.
MevastatinNot used therapeutically due to its many side effects.
BW-A 58CBW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite in man in vivo and also in human...
ERB-196Not Available
1,2-DihydroxynaphthaleneNot Available
1,6-NaphthalenediolNot Available
2,3-Dimethyl-1,4-naphthoquinoneNot Available
Trypan blue free acidA dye used as a visualizing aid to stain the epiretinal membranes during ophthalmic surgical vitrectomy procedures, thereby facilitating removal of the tissue.
DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Evans blueNot Annotated
TriethoxycaprylylsilaneNot Annotated
VTP-194204Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung Cancer.
LapachoneLapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.
GepotidacinGepotidacin has been used in trials studying the treatment of Gonorrhea, Infections, Bacterial, and Infections, Respiratory Tract.
MenatetrenoneA form of vitamin K2 which is used in the treatment of osteoporosis to stimulate osteogenesis.
NapabucasinNapabucasin has been investigated for the treatment of Colorectal Carcinoma.
ORG-25935Org 25935 has been used in trials studying the treatment of Alcoholism, Schizophrenia, and Panic Disorder.
DasotralineDasotraline is a serotonin, norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of Binge Eating Disorder, Adult Attention Hyperactivity Disorder, Attention Deficit Hyperactivity Disorder, and...
TU-100TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease, Rectal Sensation, and Gastric Emptying, among others.
PicropodophyllinPicropodophyllin has been investigated for the treatment of Non Small Cell Lung Cancer.
Menaquinone 7Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children).
NaftazoneA naphthoquinone derivative indicated in the treatment of varicose veins, hemorrhoids, and superficial thrombophlebitis.
DesmethylsertralineDesmethylsertraline is a metabolite of sertraline.
Triciribine phosphateNot Annotated
Menadiol diphosphateNot Annotated
Menaquinone 6Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
ATB-346ATB-346 is under investigation in clinical trial NCT03220633 (Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects).
MenaquinoneMenaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists).
Cetyltrimethylammonium naproxenateAn anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction.
Menadione bisulfiteNot Annotated
NaphthoquineNaphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO).
NS-8593Not Annotated
PlumbaginPlumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.
SepantroniumSepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis.
TTI-101Not Annotated
PXL-770 free acid anhydrousNot Annotated
Drugs & Drug Targets
AdapaleneRetinoic acid receptor betatarget
AdapaleneRetinoic acid receptor gammatarget
AdapaleneRetinoic acid receptor RXR-alphatarget
AdapaleneRetinoic acid receptor RXR-betatarget
AdapaleneRetinoic acid receptor RXR-gammatarget
AdapaleneTranscription factor AP-1target
AdapaleneRetinoic acid receptor alphatarget
AdapaleneAspartate aminotransferase, cytoplasmictarget
AdapaleneToll-like receptor 2target
TolnaftateSqualene monooxygenasetarget
PropranololBeta-1 adrenergic receptortarget
PropranololBeta-2 adrenergic receptortarget
PropranololBeta-3 adrenergic receptortarget
Propranolol5-hydroxytryptamine receptor 1Atarget
Propranolol5-hydroxytryptamine receptor 1Btarget
PropranololCytochrome P450 1A2enzyme
PropranololCytochrome P450 2D6enzyme
PropranololAlpha-1-acid glycoprotein 1carrier
PropranololCytochrome P450 2C19enzyme
PropranololCytochrome P450 3A4enzyme
PropranololCytochrome P450 3A5enzyme
PropranololCytochrome P450 3A7enzyme
PropranololSolute carrier family 22 member 2transporter
PropranololP-glycoprotein 1transporter
PropranololCytochrome P450 1A1enzyme
PropranololAmine oxidase [flavin-containing] Aenzyme
PropranololSerum albumincarrier
Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
SimvastatinCytochrome P450 3A4enzyme
SimvastatinCytochrome P450 2C8enzyme
SimvastatinCytochrome P450 2C9enzyme
SimvastatinCytochrome P450 3A5enzyme
SimvastatinP-glycoprotein 1transporter
SimvastatinSolute carrier organic anion transporter family member 1A2transporter
SimvastatinSolute carrier organic anion transporter family member 1B1transporter
SimvastatinCytochrome P450 2B6enzyme
SimvastatinCytochrome P450 2D6enzyme
SimvastatinUDP-glucuronosyltransferase 1-1enzyme
SimvastatinUDP-glucuronosyltransferase 1-3enzyme
SimvastatinUDP-glucuronosyltransferase 2B7enzyme
SimvastatinCanalicular multispecific organic anion transporter 1transporter
SimvastatinIntegrin alpha-Ltarget
SimvastatinBile salt export pumptransporter
SimvastatinCytochrome P450 2C19enzyme
SimvastatinSolute carrier organic anion transporter family member 2B1transporter
SimvastatinSolute carrier organic anion transporter family member 1B3transporter
SimvastatinHistone deacetylase 2target
SimvastatinCocaine esteraseenzyme
SimvastatinLiver carboxylesterase 1enzyme
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
CinacalcetExtracellular calcium-sensing receptortarget
CinacalcetCytochrome P450 3A4enzyme
CinacalcetCytochrome P450 2D6enzyme
CinacalcetCytochrome P450 1A2enzyme
PhylloquinoneVitamin K-dependent gamma-carboxylasetarget
PhylloquinoneLeukotriene-B(4) omega-hydroxylase 1enzyme
PhylloquinoneUbiA prenyltransferase domain-containing protein 1enzyme
PhylloquinoneVitamin K epoxide reductase complex subunit 1enzyme
SertralineSodium-dependent serotonin transportertarget
SertralineCytochrome P450 2B6enzyme
SertralineCytochrome P450 2C19enzyme
SertralineCytochrome P450 2C9enzyme
SertralineCytochrome P450 2D6enzyme
SertralineSodium-dependent dopamine transportertarget
SertralineCYP2B proteinenzyme
SertralineCytochrome P450 3A4enzyme
SertralineAmine oxidase [flavin-containing] Benzyme
SertralineAmine oxidase [flavin-containing] Aenzyme
SertralineP-glycoprotein 1transporter
SertralineSerum albumincarrier
SertralineSigma receptortarget
SertralineSodium-dependent noradrenaline transportertarget
SertralineEquilibrative nucleoside transporter 4target
SertralineCytochrome P450 2E1enzyme
TerbinafineSqualene monooxygenasetarget
TerbinafineCytochrome P450 2D6enzyme
TerbinafineCytochrome P450 2C9enzyme
TerbinafineCytochrome P450 1A2enzyme
TerbinafineCytochrome P450 3A4enzyme
TerbinafineCytochrome P450 2C8enzyme
TerbinafineCytochrome P450 2C19enzyme
TerbinafineProstaglandin G/H synthase 1enzyme
TerbinafineSerum albumincarrier
Terbinafinealpha1-acid glycoproteincarrier
TerbinafineABC multidrug transporter MDR2transporter
TerbinafineSqualene monooxygenasetarget
Naphthalene-2,6-disulfonic acidL-lactate dehydrogenasetarget
Naphthalene-2,6-disulfonic acidBacterioferritin comigratory proteintarget
1-Naphthylamine-5-sulfonic acidTransthyretincarrier
2-Naphthalenesulfonic acidProthrombintarget
2-Naphthalenesulfonic acidTrypsin-1target
MenadioneVitamin K epoxide reductase complex subunit 1target
MenadioneCoagulation factor IXtarget
MenadioneVitamin K-dependent gamma-carboxylasetarget
MenadioneVitamin K-dependent protein Ctarget
MenadioneVitamin K-dependent protein Starget
MenadioneNAD(P)H dehydrogenase [quinone] 1target
MenadioneRibosyldihydronicotinamide dehydrogenase [quinone]target
MenadioneVitamin K epoxide reductase complex subunit 1-like protein 1target
MenadioneXanthine dehydrogenase/oxidaseenzyme
MenadioneAldehyde oxidaseenzyme
MenadioneMethylenetetrahydrofolate reductaseenzyme
MenadioneCytochrome P450 1A1enzyme
MenadioneCytochrome P450 1A2enzyme
MenadioneCytochrome P450 2A6enzyme
MenadioneCytochrome P450 1B1enzyme
MenadioneCytochrome P450 2B6enzyme
MenadioneCytochrome P450 2C8enzyme
MenadioneCytochrome P450 2C9enzyme
MenadioneCytochrome P450 2C19enzyme
MenadioneCytochrome P450 2D6enzyme
MenadioneCytochrome P450 2E1enzyme
MenadioneCytochrome P450 3A4enzyme
MenadioneCytochrome P450 3A5enzyme
MenadioneCytochrome P450 3A7enzyme
BexaroteneRetinoic acid receptor RXR-betatarget
BexaroteneCytochrome P450 3A4enzyme
BexaroteneRetinoic acid receptor RXR-alphatarget
BexaroteneRetinoic acid receptor RXR-gammatarget
BexaroteneCytochrome P450 2C8enzyme
EtoposideDNA topoisomerase 2-alphatarget
EtoposideCytochrome P450 3A4enzyme
EtoposideCanalicular multispecific organic anion transporter 2transporter
EtoposideMultidrug resistance-associated protein 6transporter
EtoposideP-glycoprotein 1transporter
EtoposideMultidrug resistance-associated protein 1transporter
EtoposideMultidrug resistance-associated protein 7transporter
EtoposideCanalicular multispecific organic anion transporter 1transporter
EtoposideATP-binding cassette sub-family G member 2transporter
EtoposideCytochrome P450 1A2enzyme
EtoposideCytochrome P450 2E1enzyme
EtoposideCytochrome P450 3A5enzyme
EtoposideUDP-glucuronosyltransferase 1-1enzyme
EtoposideDNA topoisomerase 2-betatarget
EtoposideGlutathione S-transferase theta-1enzyme
EtoposideGlutathione S-transferase Penzyme
EtoposideProstaglandin G/H synthase 2enzyme
EtoposideProstaglandin G/H synthase 1enzyme
AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
AtovaquoneCytochrome btarget
AtovaquoneCytochrome P450 2C9enzyme
AtovaquoneCytochrome P450 3A4enzyme
AtovaquoneP-glycoprotein 1transporter
PodofiloxDNA topoisomerase 2-alphatarget
PodofiloxTubulin alpha-4A chaintarget
PodofiloxTubulin beta chaintarget
DezocineMu-type opioid receptortarget
DezocineKappa-type opioid receptortarget
LevobunololBeta-1 adrenergic receptortarget
LevobunololBeta-2 adrenergic receptortarget
LevobunololCytochrome P450 2D6enzyme
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
MibefradilCytochrome P450 3A4enzyme
MibefradilCytochrome P450 1A2enzyme
MibefradilCytochrome P450 2D6enzyme
MibefradilCytochrome P450 3A5enzyme
MibefradilCytochrome P450 3A7enzyme
MibefradilP-glycoprotein 1transporter
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
MibefradilCytochrome P450 11B1, mitochondrialenzyme
MibefradilCytochrome P450 11B2, mitochondrialenzyme
Nanaomycin DActVA 6 proteintarget
1-naphthaleneacetic acidS-phase kinase-associated protein 1target
LG-100268Retinoic acid receptor RXR-betatarget
FlaviolinPutative cytochrome P450target
DansylamideCarbonic anhydrase 2target
N,O-didansyl-L-tyrosineThymidylate synthasetarget
Mevinolinic acid3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
8-anilinonaphthalene-1-sulfonic acidUDP-N-acetylglucosamine 1-carboxyvinyltransferasetarget
8-anilinonaphthalene-1-sulfonic acidFatty acid-binding protein, adipocytecarrier
8-anilinonaphthalene-1-sulfonic acidProtein S100-A7target
8-anilinonaphthalene-1-sulfonic acidTransthyretincarrier
SuraminNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
SuraminComplement control protein C3target
SuraminPhospholipase A2, membrane associatedtarget
SuraminP2Y purinoceptor 2target
SuraminFollicle-stimulating hormone receptortarget
SuraminRyanodine receptor 1target
SuraminArylsulfatase Aenzyme
SuraminCytosolic phospholipase A2enzyme
TamibaroteneRetinoic acid receptor alphatarget
TamibaroteneRetinoic acid receptor betatarget
TamibaroteneCellular retinoic acid-binding protein 1carrier
RotigotineDopamine D3 receptortarget
RotigotineDopamine D5 receptortarget
RotigotineDopamine D4 receptortarget
RotigotineDopamine D2 receptortarget
Rotigotine5-hydroxytryptamine receptor 1Atarget
RotigotineDopamine D1 receptortarget
RotigotineCytochrome P450 2D6enzyme
RotigotineCytochrome P450 3A4enzyme
RotigotineAlpha-2B adrenergic receptortarget
RotigotineCytochrome P450 2C19enzyme
AmibegronBeta-3 adrenergic receptortarget
LasofoxifeneEstrogen receptor alphatarget
LasofoxifeneEstrogen receptor betatarget
LasofoxifeneCannabinoid receptor 2target
ElacestrantEstrogen receptor alphatarget
ElacestrantCytochrome P450 3A4enzyme
ElacestrantCytochrome P450 2A6enzyme
ElacestrantCytochrome P450 2C9enzyme
ElacestrantSolute carrier organic anion transporter family member 2B1transporter
ElacestrantP-glycoprotein 1transporter
ElacestrantATP-binding cassette sub-family G member 2transporter
Mevastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
MevastatinLiver carboxylesterase 1enzyme
ERB-196Estrogen receptor betatarget
ERB-196Nuclear receptor coactivator 1target
1,2-Dihydroxynaphthalene1,2-dihydroxynaphthalene dioxygenasetarget
2,3-Dimethyl-1,4-naphthoquinoneFumarate reductase flavoprotein subunittarget
2,3-Dimethyl-1,4-naphthoquinoneFumarate reductase iron-sulfur subunittarget
2,3-Dimethyl-1,4-naphthoquinoneFumarate reductase cytochrome b subunittarget
DasabuvirNonstructural protein 5B (NS5B)target
DasabuvirCytochrome P450 2C8enzyme
DasabuvirCytochrome P450 3A4enzyme
DasabuvirCytochrome P450 2D6enzyme
DasabuvirUDP-glucuronosyltransferase 1-1enzyme
DasabuvirATP-binding cassette sub-family G member 2transporter
DasabuvirATP-binding cassette sub-family B member 5transporter
DasabuvirP-glycoprotein 1transporter
LapachoneRetinol-binding protein 3target
DasotralineSodium-dependent dopamine transportertarget
DasotralineSodium-dependent serotonin transportertarget
DasotralineSodium-dependent noradrenaline transportertarget
DesmethylsertralineP-glycoprotein 1target