- Accession Number
Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
Drug Drug Description Menadione The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. Adapalene A third-generation topical retinoid with anti-comedogenic, comedolytic, and anti-inflammatory properties used to treat acne vulgaris in adolescents and adults. Bexarotene A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. Tolnaftate An antifungal agent used to treat various skin infections caused by fungi. Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. Simvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. Etoposide A podophyllotoxin derivative used to treat testicular and small cell lung tumors. Naproxen An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. Cinacalcet A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma. Phylloquinone A fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. Sertraline A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. Atovaquone An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. Podofilox A topical agent used for the treatment of external genital warts and perianal warts. Dezocine Indicated in the treatment of moderate to severe pain. Levobunolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Mibefradil For the treatment of angina and high blood pressure. Nanaomycin D Not Available Dansylamide Not Available N,O-didansyl-L-tyrosine Not Available Naphthalene-2,6-disulfonic acid Not Available Lawsone Not Available Suramin For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms. Tamibarotene Investigated for use/treatment in leukemia (unspecified). Amonafide Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer. Rotigotine A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. PRO 2000 Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection. Amibegron Investigated for use/treatment in depression, irritable bowel syndrome (IBS), and obesity. Lasofoxifene Investigated for use/treatment in postmenopausal osteoporosis to reduce the risk of both vertebral and novertebral fractures, as well as address other postmenopausal conditions, including reduction in risk of breast cancer... Naproxcinod Investigated for use/treatment in pain (acute or chronic), inflammatory disorders (unspecified), osteoarthritis, and arthritis and arthritic pain. Mevastatin Not used therapeutically due to its many side effects. BW-A 58C BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite in man in vivo and also in human... ERB-196 Not Available 2,3-Dimethyl-1,4-naphthoquinone Not Available 2-Naphthalenesulfonic acid Not Available Trypan blue free acid A dye used as a visualizing aid to stain the epiretinal membranes during ophthalmic surgical vitrectomy procedures, thereby facilitating removal of the tissue. Triethoxycaprylylsilane Not Annotated VTP-194204 Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung Cancer. Nirogacestat Nirogacestat has been used in trials studying the treatment of Breast Cancer, HIV Infection, Desmoid Tumors, Advanced Solid Tumors, and Aggressive Fibromatosis, among others. Menatetrenone A form of vitamin K2 which is used in the treatment of osteoporosis to stimulate osteogenesis. ORG-25935 Org 25935 has been used in trials studying the treatment of Alcoholism, Schizophrenia, and Panic Disorder. Dasotraline Dasotraline is a serotonin, norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of Binge Eating Disorder, Adult Attention Hyperactivity Disorder, Attention Deficit Hyperactivity Disorder, and... TU-100 TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease, Rectal Sensation, and Gastric Emptying, among others. Picropodophyllin Picropodophyllin has been investigated for the treatment of Non Small Cell Lung Cancer. Menaquinone 7 Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children). Bunaftine Not Annotated Naftazone A naphthoquinone derivative indicated in the treatment of varicose veins, hemorrhoids, and superficial thrombophlebitis. Desmethylsertraline Desmethylsertraline is a metabolite of sertraline. Triciribine phosphate Not Annotated Menadiol diphosphate Not Annotated 1-naphthaleneacetic acid A drug used to treat digestive problems from excessive fat consumption and functional disorders of the gallbladder and bile ducts. LG-100268 LG-100268 is a retinoid X receptor (RXR) selective compound. Dexpropranolol Not Available Lapachone Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell. Menaquinone 6 Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2). ATB-346 ATB-346 is under investigation in clinical trial NCT03220633 (Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects). Menaquinone Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists). Terbinafine An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections. Elacestrant Investigated for use/treatment in menopause and female hormonal deficiencies/abnormalities. Gepotidacin Gepotidacin has been used in trials studying the treatment of Gonorrhea, Infections, Bacterial, and Infections, Respiratory Tract. Napabucasin Napabucasin has been investigated for the treatment of Colorectal Carcinoma. Flaviolin Not Available Mevinolinic acid Not Available 1,6-Naphthalenediol Not Available 1,2-Dihydroxynaphthalene Not Available 1-Naphthylamine-5-sulfonic acid Not Available 8-anilinonaphthalene-1-sulfonic acid Not Available Cetyltrimethylammonium naproxenate An anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction. Carbaryl A medication used in shampoo to remove lice. Menadione bisulfite Not Annotated Naphthoquine Naphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO).
- Drugs & Drug Targets