Benzyl Compounds

Name
Benzyl Compounds
Accession Number
DBCAT000417
Description

Benzene derivatives that contain a benzyl group with the general formula Phenyl-CH2-R.

Drugs
DrugDrug Description
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
ButenafineA topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis.
PodofiloxA topical agent used for the treatment of external genital warts and perianal warts.
PargylineFor the treatment of moderate to severe hypertension.
2,3,4,5,6-Pentafluorobenzyl AlcoholNot Available
BenzylamineNot Available
Para-Bromobenzyl AlcoholNot Available
2-Aminobenzyl alcoholNot Available
MatairesinolNot Available
DapoxetineFor the treatment of premature ejaculation.
XimelagatranFor the treatment of acute deep vein thrombosis.
SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
Benzyl alcoholAn antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
IdalopirdineIdalopirdine has been used in trials studying the treatment of Cognition, Schizophrenia, and Alzheimer's Disease.
Vanillyl alcoholVanillyl alcohol has been used in trials studying the treatment of Smoking.
SecoisolariciresinolSecoisolariciresinol has been used in trials studying the prevention of Breast Cancer.
TerameprocolTerameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
OndelopranOndelopran has been used in trials studying the treatment of Alcohol Dependence.
CombretastatinCombretastatin has been investigated for the treatment of Anaplastic Thyroid Cancer.
PicropodophyllinPicropodophyllin has been investigated for the treatment of Non Small Cell Lung Cancer.
TeclozanTeclozan is an antiprotozoal agent employed typically as a therapy to treat protozoan infections.
Dichlorobenzyl alcoholA medication used to treat a sore throat.
MelagatranNot Annotated
MacelignanMacelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
SilibininCurrently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
2-(aminomethyl)phenol2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study in Older Adults).
MavacamtenMavacamten is under investigation in clinical trial NCT03442764 (A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)).
GW-3965GW-3965 is a liver X receptor ligand.
Drugs & Drug Targets
DrugTargetType
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolArachidonate 5-lipoxygenaseenzyme
MasoprocolSex hormone-binding globulintarget
EtoposideDNA topoisomerase 2-alphatarget
EtoposideCytochrome P450 3A4enzyme
EtoposideCanalicular multispecific organic anion transporter 2transporter
EtoposideMultidrug resistance-associated protein 6transporter
EtoposideP-glycoprotein 1transporter
EtoposideMultidrug resistance-associated protein 1transporter
EtoposideMultidrug resistance-associated protein 7transporter
EtoposideCanalicular multispecific organic anion transporter 1transporter
EtoposideATP-binding cassette sub-family G member 2transporter
EtoposideCytochrome P450 1A2enzyme
EtoposideCytochrome P450 2E1enzyme
EtoposideCytochrome P450 3A5enzyme
EtoposideUDP-glucuronosyltransferase 1-1enzyme
EtoposideDNA topoisomerase 2-betatarget
EtoposideGlutathione S-transferase theta-1enzyme
EtoposideGlutathione S-transferase Penzyme
EtoposideProstaglandin G/H synthase 2enzyme
EtoposideProstaglandin G/H synthase 1enzyme
ButenafineSqualene monooxygenasetarget
PodofiloxDNA topoisomerase 2-alphatarget
PodofiloxTubulin alpha-4A chaintarget
PodofiloxTubulin beta chaintarget
PargylineAmine oxidase [flavin-containing] Btarget
PargylineAmine oxidase [flavin-containing] Atarget
2,3,4,5,6-Pentafluorobenzyl AlcoholAlcohol dehydrogenase 1Ctarget
BenzylamineTrypsin-1target
BenzylamineTrypsin-2target
Para-Bromobenzyl AlcoholAlcohol dehydrogenase 1Ctarget
2-Aminobenzyl alcoholComplement factor Dtarget
MatairesinolDehydrogenase/reductase SDR family member 4-like 2target
Dapoxetine5-hydroxytryptamine receptor 1Atarget
Dapoxetine5-hydroxytryptamine receptor 1Btarget
Dapoxetine5-hydroxytryptamine receptor 2Ctarget
DapoxetineCytochrome P450 3A4enzyme
DapoxetineCytochrome P450 2D6enzyme
XimelagatranProthrombintarget
XimelagatranCytochrome P450 2C9enzyme
SafinamideAmine oxidase [flavin-containing] Btarget
SafinamideAmine oxidase [flavin-containing] Aenzyme
SafinamideATP-binding cassette sub-family G member 2transporter
SafinamideSolute carrier organic anion transporter family member 3A1transporter
SafinamideCytochrome P450 3A4enzyme
SafinamideCytochrome P450 1A1enzyme
SafinamideCytochrome P450 1A2enzyme
SafinamideCytochrome P450 2D6enzyme
SafinamideCytochrome P450 2C19enzyme
SafinamideCytochrome P450 3A5enzyme
Benzyl alcoholCytochrome P450 2C8enzyme
Benzyl alcoholCytochrome P450 1A1enzyme
Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
Benzyl alcoholCytochrome P450 1A2enzyme
Benzyl alcoholCytochrome P450 2E1enzyme
Benzyl alcoholCytochrome P450 2D6enzyme
VilanterolCytochrome P450 3A4enzyme
VilanterolBeta-2 adrenergic receptortarget
Dichlorobenzyl alcoholSodium channel proteintarget
SilibininSolute carrier family 22 member 6transporter
SilibininUDP-glucuronosyltransferase 1-1enzyme
SilibininSolute carrier organic anion transporter family member 1B1transporter
SilibininSolute carrier organic anion transporter family member 1B3transporter
SilibininSolute carrier organic anion transporter family member 2B1transporter
GW-3965Oxysterols receptor LXR-betatarget