Accession Number

Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.

DrugDrug Description
MitomycinAn antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
ZolmitriptanA member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
SumatriptanA serotonin receptor agonist used to treat migraines and cluster headaches.
PerindoprilAn ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction.
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
OndansetronA serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.
MelatoninAn endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement.
CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
MolindoneAn antipsychotic used to treat schizophrenia.
IsatinIsatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids. The compound is found...
OxyphenisatinA laxative that undergoes enterohepatic circulation. It may cause jaundice.
VilazodoneAn antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors.
Indigotindisulfonic acidA medication used to visualize ureteral orifices during cystoscopy and ureteral catheterization.
LurbinectedinA chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer.
MetisazoneNot Annotated
Oxyphenisatin acetateOxyphenisatin acetate is the pro-drug of oxyphenisatin (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.
FluvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
SunitinibA receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
PanobinostatA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
TropisetronA 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting.
Indoxyl sulfateNot Available
Flortaucipir F-18A small lipophilic tracer containing [18F]fluoride capable of crossing the blood-brain barrier and binding to aggregated tau protein; used in PET imaging for the diagnosis of Alzheimer's disease.
Indocyanine greenA diagnostic agent for vascular imagine and radiography of the eye, as well as liver function tests.
Indocyanine green acid formA diagnostic agent used for the determination of cardiac output, hepatic function and liver blood flow, and for ophthalmic angiography.
EletriptanA triptan used for the treatment of migraines.
DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
AlmotriptanA 5-HT1B/1D receptor agonist used to treat migraines.
NaratriptanA 5-HT1B/1D receptor agonist used to treat migraines.
RizatriptanA triptan used to treat migraines with or without aura.
FrovatriptanA 5-HT1B/1D receptor agonist used to treat migraines.
BufotenineA hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a...
IndopanIndopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention...
DiethyltryptamineDiethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
DimethyltryptamineSome people use this compound as a psychedelic inducing agent.
EtryptamineDeveloped in the 1960's for use as an antidepressant before market withdrawal in 1962.
N-acetylserotoninNot Available
TryptamineNot Available
SerotoninFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
SerdemetanSerdemetan has been used in trials studying the treatment of Neoplasms.
IprindoleNot Annotated
ReserpineFor the treatment of hypertension
VindesineA vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
VinorelbineA vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
CarprofenFor use as a pain reliever in the treatment of joint pain and post-surgical pain.
AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
PhysostigmineA cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity.
DeserpidineAn alkaloid that has been used to manage hypertension.
RescinnamineFor the treatment of hypertension.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
AjmalineAn antiarrhythmic used to manage a variety of forms of tachycardias.
AlmitrineFor the treatment of chronic obstructive pulmonary disease.
5-Methoxy-N,N-diisopropyltryptamine5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a...
7-HydroxystaurosporineNot Available
StaurosporineAn indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
K-252aNot Available
DeacetoxyvinzolidineNot Available
LintitriptFor the treatment of pancreatic cancer and appetite disorders.
VoacamineFor the treatment of malaria. Also under investigation for the modulation of multidrug resistance in cancer cells.
EdotecarinClinical studies with edotecarin have shown activity in subjects with colorectal cancer, esophageal cancer and other solid tumors.
CilansetronFor the treatment of symptoms associated with irritable bowel syndrome.
PhenserineFor the treatment of Alzheimer's disease (AD).
VintafolideInvestigated for use/treatment in solid tumors.
PTC299Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
CEP-1347Investigated for use/treatment in asthma and parkinson's disease.
BecatecarinInvestigated for use/treatment in cancer/tumors (unspecified), liver cancer, gastric cancer, and leukemia (unspecified).
LestaurtinibInvestigated for use/treatment in pancreatic cancer, prostate cancer, and leukemia (myeloid).
PorfiromycinInvestigated for use/treatment in head and neck cancer.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
LidorestatNot Available
CarbazoleNot Available
HarmineNot Available
Indoleacetic acidNot Available
N-(indole-3-acetyl)-L-aspartic acidNot Available
IndoleacetamideNot Available
CarbazochromeIndicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura.
PirlindoleFor the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving...
MetralindoleInvestigated for the treatment of depression.
Rauwolfia serpentina rootRauwolfia alkaloids are indicated in the treatment of hypertension . Rauwolfia alkaloids have been used for relief of symptoms in agitated psychotic states such as schizophrenia; however, use as antipsychotics...
AlectinibA kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
MetoserpateNot Annotated
VinflunineA vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
PsilocybinPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
OC-459OC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.
FevipiprantFevipiprant has been used in trials studying the treatment of Asthma, Atopic Dermatitis, and Allergic Rhinitis.
OrantinibOrantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others.
VinpocetineA synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease.
BizelesinBizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
ApaziquoneApaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms.
TAK-901TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.
PactimibePactimibe has been used in trials studying the treatment of Atherosclerosis and Coronary Heart Disease.
RamatrobanRamatroban has been used in trials studying the treatment of Asthma.
VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
TenidapNot Annotated
ProglumetacinA non-steroidal anti-inflammatory medication used to manage pain associated with various inflammatory conditions including rheumatoid arthritis and osteoarthritis.
IprazochromeNot Annotated
PrajmalineNot Annotated
BietaserpineNot Annotated
LorajmineNot Annotated
AcemetacinA NSAID indicated in the treatment of pain and inflammation.
VinburnineNot Annotated
MebhydrolinAn antihistamine indicated in the treatment of allergies.
HarmalineNot Annotated
SelisistatSelective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for...
5-methoxy-N,N-dimethyltryptamine5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug,...
RebeccamycinRebeccamycin is a weak topoisomerase I inhibitor isolated from Nocardia sp.
CEP-9722CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
FlortaucipirFlortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
18-methoxycoronaridine18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).
PosiphenPosiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
TozuleristideTozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
RaubasineNot Annotated
StrychnineNot Annotated
Carbazochrome sulfonic acidA hemostatic agent indicated to treat bleeding in capillary fragility.
Cytochalasin BNot Annotated
IndigoNot Annotated
TIK-301Not Annotated
EllipticineEllipticine is a potent antineoplastic agent.
Go-6976An inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
ZK-93423ZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.
TapencariumNot Annotated
EmvododstatNot Annotated
ESK981Not Annotated
Drugs & Drug Targets
MitomycinNADPH--cytochrome P450 reductaseenzyme
Zolmitriptan5-hydroxytryptamine receptor 1Dtarget
Zolmitriptan5-hydroxytryptamine receptor 1Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Ftarget
ZolmitriptanCytochrome P450 1A2enzyme
ZolmitriptanAmine oxidase [flavin-containing] Aenzyme
Zolmitriptan5-hydroxytryptamine receptor 1Atarget
ZolmitriptanP-glycoprotein 1transporter
Zolmitriptan5-hydroxytryptamine receptor 7target
Zolmitriptan5-hydroxytryptamine receptor 2Atarget
Zolmitriptan5-hydroxytryptamine receptor 2Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Etarget
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
IndomethacinInterferon-induced, double-stranded RNA-activated protein kinasetarget
IndomethacinHuman Cyclooxygenasestarget
Sumatriptan5-hydroxytryptamine receptor 1Dtarget
Sumatriptan5-hydroxytryptamine receptor 1Btarget
Sumatriptan5-hydroxytryptamine receptor 1Ftarget
SumatriptanAmine oxidase [flavin-containing] Aenzyme
Sumatriptan5-hydroxytryptamine receptor 1Atarget
SumatriptanSolute carrier organic anion transporter family member 1A2transporter
SumatriptanP-glycoprotein 1transporter
SumatriptanATP-binding cassette sub-family G member 2transporter
SumatriptanSolute carrier organic anion transporter family member 1B1transporter
PerindoprilAngiotensin-converting enzymetarget
PerindoprilSolute carrier family 15 member 1transporter
PerindoprilSolute carrier family 15 member 2transporter
PerindoprilSecreted frizzled-related protein 4target
IndapamideCytochrome P450 3A4enzyme
IndapamideSolute carrier family 12 member 3target
IndapamideEpoxide hydrolase 1enzyme
Indapamidealpha1-acid glycoproteincarrier
IndapamideSerum albumincarrier
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
Ondansetron5-hydroxytryptamine receptor 3Atarget
OndansetronCytochrome P450 3A4enzyme
OndansetronCytochrome P450 1A2enzyme
OndansetronCytochrome P450 2D6enzyme
OndansetronCytochrome P450 3A5enzyme
OndansetronCytochrome P450 3A7enzyme
Ondansetron5-hydroxytryptamine receptor 4target
Ondansetron5-hydroxytryptamine receptor 1Atarget
Ondansetron5-hydroxytryptamine receptor 1Btarget
OndansetronMu-type opioid receptortarget
OndansetronCytochrome P450 2C9enzyme
OndansetronCytochrome P450 2E1enzyme
MelatoninAcetylserotonin O-methyltransferasetarget
MelatoninMelatonin receptor type 1Atarget
MelatoninMelatonin receptor type 1Btarget
MelatoninNuclear receptor ROR-betatarget
MelatoninRibosyldihydronicotinamide dehydrogenase [quinone]target
MelatoninEstrogen receptor alphatarget
MelatoninEosinophil peroxidasetarget
MelatoninCytochrome P450 1A1enzyme
MelatoninCytochrome P450 1A2enzyme
MelatoninCytochrome P450 2C19enzyme
MelatoninCytochrome P450 2C9enzyme
MelatoninAcetylserotonin O-methyltransferaseenzyme
MelatoninIndoleamine 2,3-dioxygenase 1enzyme
MelatoninCytochrome P450 1B1enzyme
MelatoninSolute carrier family 22 member 8transporter
MelatoninCytochrome P450 19A1enzyme
CarvedilolAlpha-1A adrenergic receptortarget
CarvedilolBeta-1 adrenergic receptortarget
CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
CarvedilolBeta-2 adrenergic receptortarget
CarvedilolVascular endothelial growth factor Atarget
CarvedilolNatriuretic peptides Btarget
CarvedilolGap junction alpha-1 proteintarget
CarvedilolPotassium voltage-gated channel subfamily H member 2target
CarvedilolVascular cell adhesion protein 1target
CarvedilolCytochrome P450 2C9enzyme
CarvedilolCytochrome P450 2D6enzyme
CarvedilolXanthine dehydrogenase/oxidaseenzyme
CarvedilolP-glycoprotein 1transporter
CarvedilolCytochrome P450 1A2enzyme
CarvedilolCytochrome P450 3A4enzyme
CarvedilolCytochrome P450 1A1enzyme
CarvedilolCytochrome P450 2E1enzyme
CarvedilolAlpha-1D adrenergic receptortarget
CarvedilolAlpha-1B adrenergic receptortarget
CarvedilolAlpha-2C adrenergic receptortarget
CarvedilolAlpha-2B adrenergic receptortarget
CarvedilolAlpha-2A adrenergic receptortarget
CarvedilolHypoxia-inducible factor 1-alphatarget
CarvedilolInward rectifier potassium channel 4target
CarvedilolUDP-glucuronosyltransferase 1-1enzyme
CarvedilolSerum albumincarrier
CarvedilolUDP-glucuronosyltransferase 2B4enzyme
CarvedilolUDP-glucuronosyltransferase 2B7enzyme
CarvedilolInward rectifier potassium channel 2target
CarvedilolAlpha-1 adrenergic receptorstarget
MolindoneDopamine D2 receptortarget
Molindone5-hydroxytryptamine receptor 1Atarget
Molindone5-hydroxytryptamine receptor 2Atarget
MolindoneMuscarinic acetylcholine receptor M1target
IsatinAmine oxidase [flavin-containing] Btarget
IsatinAmine oxidase [flavin-containing] Benzyme
Vilazodone5-hydroxytryptamine receptor 1Atarget
VilazodoneCytochrome P450 3A4enzyme
VilazodoneCytochrome P450 2D6enzyme
VilazodoneSodium-dependent serotonin transportertarget
VilazodoneCytochrome P450 2C19enzyme
Indigotindisulfonic acidAlpha adrenergic receptortarget
LurbinectedinCytochrome P450 3A4enzyme
LurbinectedinSerum albumincarrier
LurbinectedinAlpha-1-acid glycoprotein 1carrier
LurbinectedinP-glycoprotein 1transporter
LurbinectedinSolute carrier organic anion transporter family member 1B1transporter
LurbinectedinSolute carrier organic anion transporter family member 1B3transporter
LurbinectedinSolute carrier family 22 member 1transporter
Fluvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
FluvastatinCytochrome P450 2C9enzyme
FluvastatinCytochrome P450 3A4enzyme
FluvastatinCytochrome P450 2C8enzyme
FluvastatinCytochrome P450 2D6enzyme
FluvastatinCytochrome P450 2C19enzyme
FluvastatinCytochrome P450 1A1enzyme
FluvastatinSolute carrier organic anion transporter family member 1B1transporter
FluvastatinSolute carrier organic anion transporter family member 1B3transporter
FluvastatinSolute carrier organic anion transporter family member 2B1transporter
FluvastatinSolute carrier family 15 member 1transporter
FluvastatinCytochrome P450 3A5enzyme
FluvastatinUDP-glucuronosyltransferase 1-1enzyme
FluvastatinUDP-glucuronosyltransferase 1-3enzyme
FluvastatinUDP-glucuronosyltransferase 2B7enzyme
FluvastatinCanalicular multispecific organic anion transporter 1transporter
FluvastatinCytochrome P450 2B6enzyme
FluvastatinHistone deacetylase 2target
SunitinibPlatelet-derived growth factor receptor betatarget
SunitinibVascular endothelial growth factor receptor 1target
SunitinibVascular endothelial growth factor receptor 2target
SunitinibVascular endothelial growth factor receptor 3target
SunitinibMast/stem cell growth factor receptor Kittarget
SunitinibReceptor-type tyrosine-protein kinase FLT3target
SunitinibMacrophage colony-stimulating factor 1 receptortarget
SunitinibPlatelet-derived growth factor receptor alphatarget
SunitinibCytochrome P450 3A4enzyme
SunitinibCytochrome P450 3A5enzyme
SunitinibCytochrome P450 3A7enzyme
SunitinibMultidrug resistance-associated protein 4transporter
SunitinibP-glycoprotein 1transporter
SunitinibCanalicular multispecific organic anion transporter 1transporter
SunitinibATP-binding cassette sub-family G member 2transporter
SunitinibHepatocyte growth factor receptortarget
PanobinostatCytochrome P450 2D6enzyme
PanobinostatCytochrome P450 3A4enzyme
PanobinostatP-glycoprotein 1transporter
PanobinostatHistone deacetylasetarget
VemurafenibSerum albumincarrier
VemurafenibAlpha-1-acid glycoprotein 1carrier
VemurafenibCytochrome P450 1A2enzyme
VemurafenibCytochrome P450 2D6enzyme
VemurafenibCytochrome P450 3A4enzyme
VemurafenibSerine/threonine-protein kinase B-raftarget
VemurafenibMultidrug resistance-associated protein 1transporter
VemurafenibATP-binding cassette sub-family G member 2transporter
VemurafenibCytochrome P450 2C9enzyme
VemurafenibCytochrome P450 2C8enzyme
VemurafenibCytochrome P450 2B6enzyme
VemurafenibP-glycoprotein 1transporter
Tropisetron5-hydroxytryptamine receptor 3Atarget
Indoxyl sulfateSerum albumincarrier
Flortaucipir F-18Microtubule-associated protein tautarget
Flortaucipir F-18Amine oxidase [flavin-containing] Atarget
Flortaucipir F-18Amine oxidase [flavin-containing] Btarget
Indocyanine green acid formCanalicular multispecific organic anion transporter 1transporter
Indocyanine green acid formIsocitrate dehydrogenase [NADP] cytoplasmicenzyme
Indocyanine green acid formBile salt export pumptransporter
Eletriptan5-hydroxytryptamine receptor 1Dtarget
Eletriptan5-hydroxytryptamine receptor 1Atarget
Eletriptan5-hydroxytryptamine receptor 1Ftarget
Eletriptan5-hydroxytryptamine receptor 1Btarget
EletriptanCytochrome P450 3A4enzyme
EletriptanCytochrome P450 2D6enzyme
EletriptanCytochrome P450 2C9enzyme
EletriptanCytochrome P450 2C19enzyme
EletriptanProstaglandin G/H synthase 1enzyme
EletriptanCytochrome P450 2A6enzyme
EletriptanP-glycoprotein 1transporter
DelavirdineCytochrome P450 3A4enzyme
DelavirdineCytochrome P450 2C9enzyme
DelavirdineCytochrome P450 2D6enzyme
DelavirdineCytochrome P450 3A5enzyme
DelavirdineCytochrome P450 3A7enzyme
DelavirdineCytochrome P450 2C19enzyme
DelavirdineReverse transcriptase/RNaseHtarget
Almotriptan5-hydroxytryptamine receptor 1Dtarget
Almotriptan5-hydroxytryptamine receptor 1Btarget
AlmotriptanCytochrome P450 3A4enzyme
AlmotriptanCytochrome P450 2D6enzyme
AlmotriptanAmine oxidase [flavin-containing] Aenzyme
AlmotriptanDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
AlmotriptanCytochrome P450 2C19enzyme
AlmotriptanCytochrome P450 2E1enzyme
AlmotriptanCytochrome P450 2C8enzyme
Naratriptan5-hydroxytryptamine receptor 1Dtarget
Naratriptan5-hydroxytryptamine receptor 1Btarget
Naratriptan5-hydroxytryptamine receptor 1Ftarget
Naratriptan5-hydroxytryptamine receptor 1Atarget
NaratriptanAmine oxidase [flavin-containing] Aenzyme
Rizatriptan5-hydroxytryptamine receptor 1Dtarget
Rizatriptan5-hydroxytryptamine receptor 1Btarget
Rizatriptan5-hydroxytryptamine receptor 1Ftarget
RizatriptanAmine oxidase [flavin-containing] Aenzyme
RizatriptanCytochrome P450 2D6enzyme
Rizatriptan5-hydroxytryptamine receptor 1Atarget
Rizatriptan5-hydroxytryptamine receptor 1Etarget
Rizatriptan5-hydroxytryptamine receptor 7target
Frovatriptan5-hydroxytryptamine receptor 1Dtarget
Frovatriptan5-hydroxytryptamine receptor 1Btarget
FrovatriptanCytochrome P450 1A2enzyme
BufotenineAmine oxidase [flavin-containing] Aenzyme
Dimethyltryptamine5-hydroxytryptamine receptor 6target
Dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
DimethyltryptamineSigma non-opioid intracellular receptor 1target
N-acetylserotoninSepiapterin reductasetarget
TryptamineAralkylamine dehydrogenase light chaintarget
TryptamineAralkylamine dehydrogenase heavy chaintarget
SerotoninSolute carrier family 22 member 2transporter
SerotoninSodium-dependent serotonin transportertarget
Serotonin5-hydroxytryptamine receptor 2Atarget
Serotonin5-hydroxytryptamine receptor 3Atarget
Serotonin5-hydroxytryptamine receptor 3Btarget
SerotoninSynaptic vesicular amine transportertarget
IndoraminAlpha-1A adrenergic receptortarget
ReserpineSynaptic vesicular amine transportertarget
ReserpineP-glycoprotein 1transporter
ReserpineSolute carrier family 22 member 1transporter
ReserpineBile salt export pumptransporter
ReserpineCanalicular multispecific organic anion transporter 1transporter
ReserpineSolute carrier family 22 member 2transporter
ReserpineCytochrome P450 3A5enzyme
ReserpineChromaffin granule amine transportertarget
ReserpineBaculoviral IAP repeat-containing protein 5target
ReserpineSolute carrier organic anion transporter family member 1B1transporter
ReserpineSolute carrier organic anion transporter family member 2B1transporter
VindesineTubulin beta-1 chaintarget
VindesineCytochrome P450 3A4enzyme
VinorelbineTubulin beta chaintarget
VinorelbineCytochrome P450 3A4enzyme
VinorelbineCytochrome P450 2D6enzyme
VincristineTubulin beta chaintarget
VincristineCytochrome P450 3A4enzyme
VincristineCytochrome P450 3A5enzyme
VincristineCytochrome P450 3A7enzyme
VincristineP-glycoprotein 1transporter
VincristineCanalicular multispecific organic anion transporter 2transporter
VincristineSolute carrier family 22 member 3transporter
VincristineMultidrug resistance-associated protein 1transporter
VincristineMultidrug resistance-associated protein 7transporter
VincristineCanalicular multispecific organic anion transporter 1transporter
VincristineBile salt export pumptransporter
VincristineATP-binding cassette sub-family G member 2transporter
VincristineTubulin alpha-4A chaintarget
VincristineRalA-binding protein 1transporter
VincristineSolute carrier organic anion transporter family member 1B1transporter
VincristineSolute carrier organic anion transporter family member 1B3transporter
VinblastineTubulin beta chaintarget
VinblastineTranscription factor AP-1target
VinblastineCytochrome P450 3A4enzyme
VinblastineP-glycoprotein 1transporter
VinblastineMultidrug resistance-associated protein 1transporter
VinblastineCanalicular multispecific organic anion transporter 1transporter
VinblastineMultidrug resistance-associated protein 6transporter
VinblastineBile salt export pumptransporter
VinblastineTubulin alpha-1A chaintarget
VinblastineTubulin delta chaintarget
VinblastineTubulin epsilon chaintarget
VinblastineTubulin gamma-1 chaintarget
VinblastineCytochrome P450 2D6enzyme
VinblastineSolute carrier organic anion transporter family member 1B1transporter
EtodolacProstaglandin G/H synthase 1target
EtodolacProstaglandin G/H synthase 2target
EtodolacCytochrome P450 2C9enzyme
EtodolacUDP-glucuronosyltransferase 1-9enzyme
EtodolacRetinoic acid receptor RXR-alphatarget
EtodolacSerum albumincarrier
EtodolacSolute carrier family 22 member 6transporter
EtodolacUDP-glucuronosyltransferase 1-3enzyme
EtodolacUDP-glucuronosyltransferase 1-10enzyme
EtodolacUDP-glucuronosyltransferase 2B7enzyme
CarprofenProstaglandin G/H synthase 2target
CarprofenProstaglandin G/H synthase 1target
CarprofenSolute carrier family 22 member 6transporter
Alosetron5-hydroxytryptamine receptor 3Atarget
AlosetronCytochrome P450 1A2enzyme
AlosetronCytochrome P450 2C9enzyme
AlosetronCytochrome P450 3A4enzyme
AlosetronCytochrome P450 2E1enzyme
PhysostigmineNeuronal acetylcholine receptor subunit alpha-4target
PhysostigmineNeuronal acetylcholine receptor subunit beta-2target
DeserpidineSynaptic vesicular amine transportertarget
RescinnamineAngiotensin-converting enzymetarget
YohimbineAlpha-2A adrenergic receptortarget
YohimbineAlpha-2B adrenergic receptortarget
YohimbineAlpha-2C adrenergic receptortarget
Yohimbine5-hydroxytryptamine receptor 1Atarget
Yohimbine5-hydroxytryptamine receptor 1Btarget
Yohimbine5-hydroxytryptamine receptor 1Dtarget
YohimbineDopamine D2 receptortarget
YohimbineDopamine D3 receptortarget
Yohimbine5-hydroxytryptamine receptor 2Atarget
Yohimbine5-hydroxytryptamine receptor 2Ctarget
YohimbineCytochrome P450 2D6enzyme
YohimbineCytochrome P450 3A4enzyme
YohimbineATP-sensitive potassium channeltarget
Yohimbine5-hydroxytryptamine receptor 2Btarget
AjmalineAlpha-1-acid glycoprotein 1carrier
AjmalineSodium channel protein type 5 subunit alphatarget
AlmitrineSodium/potassium-transporting ATPase subunit alpha-1target
7-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
StaurosporineTyrosine-protein kinase Lcktarget
StaurosporineSerine/threonine-protein kinase pim-1target
StaurosporineTyrosine-protein kinase ITK/TSKtarget
StaurosporineTyrosine-protein kinase SYKtarget
StaurosporineMAP kinase-activated protein kinase 2target
StaurosporineGlycogen synthase kinase-3 betatarget
StaurosporineTyrosine-protein kinase CSKtarget
StaurosporineCyclin-dependent kinase 2target
StaurosporinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
Staurosporine3-phosphoinositide-dependent protein kinase 1target
StaurosporineProtein kinase C theta typetarget
StaurosporineTyrosine-protein kinase ZAP-70target
StaurosporineP-glycoprotein 1transporter
StaurosporineMuscarinic acetylcholine receptor M1target
StaurosporineProtein kinase Ctarget
K-252aHepatocyte growth factor receptortarget
K-252aDual specificity mitogen-activated protein kinase kinase 1target
LintitriptCholecystokinin receptor type Atarget
VoacamineP-glycoprotein 1target
VoacamineP-glycoprotein 1transporter
EdotecarinDNA topoisomerase 1target
Cilansetron5-hydroxytryptamine receptor 3Atarget
PhenserineAmyloid beta A4 proteintarget
VintafolideFolate receptor betatarget
VintafolideFolate receptor gammatarget
VintafolideFolate receptor alphatarget
CEP-1347Mitogen-activated protein kinase 12target
BecatecarinDNA topoisomerase 2-alphatarget
BecatecarinDNA topoisomerase 2-betatarget
LestaurtinibReceptor-type tyrosine-protein kinase FLT3target
LestaurtinibCytochrome P450 3A4enzyme
PorfiromycinXanthine dehydrogenase/oxidaseenzyme
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
LidorestatAldose reductasetarget
CarbazoleFerredoxin CarActarget
CarbazoleTerminal oxygenase component of carbazoletarget
HarmineAmine oxidase [flavin-containing] Atarget
Indoleacetic acidGroup IIE secretory phospholipase A2target
Indoleacetic acidS-phase kinase-associated protein 1target
Indoleacetic acidKynurenine--oxoglutarate transaminase 1target
N-(indole-3-acetyl)-L-aspartic acidTryptophan synthase alpha chaintarget
N-(indole-3-acetyl)-L-aspartic acidTryptophan synthase beta chaintarget
IndoleacetamideAralkylamine dehydrogenase light chaintarget
IndoleacetamideAralkylamine dehydrogenase heavy chaintarget
PirlindoleAmine oxidase [flavin-containing] Atarget
Pirlindole5-hydroxytryptamine receptor 1Atarget
PirlindoleAlpha-2A adrenergic receptortarget
PirlindoleAmine oxidase [flavin-containing] Aenzyme
Rauwolfia serpentina rootSynaptic vesicular amine transportertarget
Rauwolfia serpentina rootMonoamine oxidaseenzyme
Rauwolfia serpentina rootSodium-dependent noradrenaline transportertransporter
Rauwolfia serpentina rootSynaptic vesicular amine transportertransporter
AlectinibALK tyrosine kinase receptortarget
AlectinibATP-binding cassette sub-family G member 2transporter
AlectinibP-glycoprotein 1transporter
VinflunineATP-binding cassette sub-family B member 5transporter
VinflunineP-glycoprotein 1transporter
VinflunineSerum albumincarrier
Vinfluninealpha1-acid glycoproteincarrier
VinflunineCytochrome P450 3A4enzyme
VinflunineTubulin beta chaintarget
VinpocetineCytochrome P450 3A4enzyme
TAK-901Aurora kinase Btarget
TAK-901Apoptosis regulator BAXtarget
RamatrobanProstaglandin D2 receptor 2target
AcemetacinProstaglandin G/H synthase 1target
AcemetacinProstaglandin G/H synthase 2target
AcemetacinUDP-glucuronosyltransferase 2B7enzyme
AcemetacinMultidrug resistance-associated protein 1transporter
HarmalineHistamine N-methyltransferasetarget
SelisistatNAD-dependent protein deacetylase sirtuin-1target
5-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 1Atarget
5-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
5-methoxy-N,N-dimethyltryptamineCytochrome P450 2D6enzyme
IndigoAryl hydrocarbon receptortarget