- Accession Number
- DBCAT002135 (DBCAT000164)
Drugs used to treat or prevent skin disorders or for the routine care of skin.
- ATC Classification
Drug Drug Description Meclocycline A tetracycline antibiotic indicated in the treatment of susceptible skin infections, bacterial vaginitis, vulvovaginitis, and cervicitis. Mercuric iodide Not Available Tiratricol A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. Fluticasone propionate A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. Infliximab A monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Cyclosporine A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. Alefacept A recombinant fusion protein that binds CD2 and is used treat moderate to severe plaque psoriasis. Riboflavin A vitamin used to correct vitamin B2 deficiency. Cyproheptadine A combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome. Loratadine A second generation antihistamine used to manage the symptoms of allergic rhinitis. Verteporfin A benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration. Bentoquatam Used to prevent or reduce the severity of allergic contact dermatitis due to urushiol, the allergenic resin of poison ivy, poison oak, and poison sumac. Hydroxyzine An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria. Methotrexate An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis. Porfimer sodium A hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus. Carprofen For use as a pain reliever in the treatment of joint pain and post-surgical pain. Aminolevulinic acid A porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Chlorpheniramine A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. Alimemazine An antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria. Oxybenzone A sunscreen agent found in sunscreens that absorbs UV rays. Benzophenone An ingredient used in sunscreens to absorb UV radiation. Protoporphyrin Not Available Glycolic acid Not Available Acetophenone Not Available Lawsone Not Available Benoxaprofen The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... Motexafin lutetium Investigated for use/treatment in brain cancer, breast cancer, cervical dysplasia/cancer, prostate cancer, cancer/tumors (unspecified), coronary artery disease, macular degeneration, and peripheral vascular disease. Motexafin gadolinium Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's). Ustekinumab A targeted antibody therapy used to manage inflammatory conditions such as plaque psoriasis, psoriatic arthritis, Crohn's Disease, and ulcerative colitis. Maxacalcitol Not Annotated Rostaporfin Investigated for use/treatment in macular degeneration. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Dimethyl fumarate A medication used to treat patients with the relapsing-remitting form of multiple sclerosis. Podophyllin A cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata). Zinc oxide A mineral ingredient of various pharmacological preparations to treat diaper dermatitis and other skin conditions, to protect the epidermis, and to prevent sunburn. Zinc sulfate A drug used to replenish low levels of zinc or prevent zinc deficiency, or to test for zinc deficiency. Avobenzone A sunscreen agent found in sunscreens that absorbs UV rays. Simethicone An anti-flatulence agent used to relieve pressure, bloating, and symptoms referred to as gas. Ecamsule A sunscreen agent found in sunscreens that absorbs UV rays. Titanium dioxide A sunscreen agent found in sunscreens that absorbs UV rays. Mineral oil Mineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive... Petrolatum For use as an over the counter skin protectant [FDA Label]. Commonly used to treat diaper rash and chapped lips [FDA Label] . Coal tar Relieving itching, irritation, redness, dryness, scaling, and flaking of the skin caused by psoriasis, seborrhea, or eczema. Allantoin An ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Padimate O An ingredient used in sunscreens to absorb UV radiation. Temoporfin A photosensitizer used to treat squamous cell carcinomas of the head and neck. Talaporfin Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia. Liarozole Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar. Collagenase clostridium histolyticum A collagenase enzyme used to promote debridement of necrotic tissue in burns and skin ulcers as well as to treat Dupuytren's contracture and Peyronie's disease. Becaplermin A recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area. Adapalene A third-generation topical retinoid with anti-comedogenic, comedolytic, and anti-inflammatory properties used to treat acne vulgaris in adolescents and adults. Diflorasone A topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort. Alclometasone A topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses. Idoxuridine A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Amcinonide A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses. Pimecrolimus A topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons. Beclomethasone dipropionate An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. Griseofulvin An antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes. Mupirocin An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes. Acitretin An oral retinoid used in the treatment of severe psoriasis. Brimonidine An alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea. Tolnaftate An antifungal agent used to treat various skin infections caused by fungi. Desoximetasone A glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Azelaic acid A saturated dicarboxylic acid used to treat mild to moderate acne vulgaris. Methoxsalen A furocoumarin used to treat psoriasis and vitiligo. Ulobetasol A lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Monobenzone A hydroquinone derivative used to treat vitiligo. Ivermectin An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. Demeclocycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Docosanol An antiviral used to treat orofacial herpes sores. Sulfacetamide A corticosteroid used to treat inflammatory ocular conditions and acne vulgaris. Imiquimod A toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata. Naftifine An antifungal agent used to treat infections of the Tinea, Trichophyton, and Epidermophyton species. Tretinoin A vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles. Hexachlorophene A chlorinated bisphenol antiseptic used as a surgical scrub and skin cleanser. Mometasone A corticosteroid with no indications. Tripelennamine A histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold. Haloprogin Used to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor. Tazarotene An acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis. Clocortolone A corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp. Flurandrenolide A corticosteroid used to treat corticosteroid-responsive dermatoses. Chlorphenesin A phenol ether used to treat painful muscular conditions. Terbinafine An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections. Prednisolone A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. Chlorhexidine An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis. Oxybuprocaine A local anesthetic used in ophthalmology. Etretinate For the treatment of severe psoriasis in adults. Selenium Sulfide An antifungal used to treat dandruff, seborrheic dermatitis of the scalp, and tinea capitis. Isotretinoin A retinoid used to treat severe recalcitrant acne. Tioconazole An imidazole antifungal used to treat vulvovaginal candidiasis. Butenafine A topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis. Miconazole An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis. Prednicarbate A medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions. Podofilox A topical agent used for the treatment of external genital warts and perianal warts. Ciclopirox A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients. Clindamycin A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Retapamulin A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes. Desonide A topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Sinecatechins A topical agent used to treat external genital and perianal warts in immunocompetent adult patients. Pheniramine An antihistamine used to treat allergic rhinitis and pruritus. Fumaric acid Not Available Cetrimonium A compound that can be used as a topical antiseptic. Calcipotriol A topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis. Isopropyl alcohol An antiseptic and disinfectant used in a variety of clinical and domestic settings. Aminobenzoic acid A drug used to reduce the progression of penile deviation in Peyronie's Disease in adults. Inosine A nutritional supplement touted to improve athletic performance and a drug used in vitro as a red blood cell rejuvenator for a unit of red blood cells that will be used in a clinical setting. Trioxsalen A psoralen derivative that has been used in combination with UV light to treat vitiligo, but has been discontinued by its manufacturer. Bifonazole An azole antifungal drug used to treat fungal skin infections, such as dermatomycosis. Afamelanotide An injectable subcutaneous implant used to mitigate phototoxicity secondary to erythropoietic protoporphyria (EPP). Ingenol mebutate A topical agent used for the treatment of actinic keratosis. Iodine An ingredient of nutritional supplements that is also used for disinfection. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Mepyramine An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. Beta carotene A vitamin A precursor found in various nutritional supplements and health products. Difluprednate A topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery. Halcinonide A corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Pyrithione An antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis. Sulconazole A topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains. Triclosan An antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew. Dimetindene A 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies. Hyaluronic acid A glycosaminoglycan used for the relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications. Luliconazole A topical antifungal agent used to treat fungal infections. Fluprednidene Fluprednidene is a corticosteroid. Chlorphenoxamine An antihistamine used as an antipruritic. Efinaconazole An antifungal agent used to treat onychomycosis, a fungal infection of the nail. Amorolfine A morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis. Chlortetracycline The first tetracycline antibiotic most commonly used for veterinary purposes. Difluocortolone A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis. Benzoyl peroxide An antibacterial and anti-inflammatory agent used for the symptomatic treatment of mild to moderate acne vulgaris and rosacea. Pramocaine A local anesthetic and antipruritic agent found in various topical preparations. Octinoxate A sunscreen agent found in sunscreens that absorbs UV rays. Mequinol A topical agent used in combination with tretinoin to treat solar lentigines. Hydroquinone A topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles. Silver nitrate Silver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a... Resorcinol Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L2727, F61] or as topical antibacterial skin... Undecylenic acid An antifungal used to treat tinea species infections. Chloroxylenol An antimicrobial used to treat cuts, bites, stings, abrasions, and used as an antiseptic hand cleaner. Hypochlorite An antimicrobial used to treat and prevent infections of the skin and tissue. Anthralin An anthracene used to treat stable plaque psoriasis. Trypsin A naturally occurring proteolytic enzyme found in the digestive tract of mammals. Used clinically in combination with bromelain and rutosides in the treatment of some inflammatory conditions. Aluminum oxide Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in... Chlorophetanol Chlorophetanol is an agent known to have antifungal activities. Virginiamycin Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent... Aminacrine A slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties. Aluminum chlorohydrate A compound used as an antiperspirant. Thimerosal Used as preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes vaccines [L1671, L1672, L1673]. Clobetasol Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. Bergapten Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis). Polihexanide Polihexanide has been used in trials studying the treatment, prevention, and supportive care of Caries, Neoplasm, Skin Diseases, Nail Diseases, and Dental Plaque, among others. Nadifloxacin A topical fluoroquinolone used in the treatment of acne and topical bacterial skin infections. Silver Indicated for the treatment of acne for topical use or the management of dental caries for dental use. Enoxolone Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME). Ethacridine Not Annotated Sodium chlorite Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food... Fluocortin Fluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain . Lysozyme An enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex. Bromelains A protease indicated in the treatment of inflammation and for eschar removal. Benzododecinium Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic. Tromantadine Tromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex. Propamidine Not Annotated Hachimycin Not Annotated Tolpropamine Not Annotated Euflavine A topical disinfectant indicated in the treatment of wounds, blisters, insect bites, and infected wounds. Tioxolone Not Annotated Mercuric amidochloride Not Annotated Tolciclate Not Annotated Oxaceprol Not Annotated Motretinide Not Annotated Diiodohydroxypropane Not Annotated Phenylmercuric nitrate Not Annotated Merbromin A topical antiseptic indicated in the disinfection of lacerations. Edoxudine A deoxythymidine analog used to treat herpetic keratitis. Fenticonazole An imidazole antifungal used to treat a variety of topical fungal infections. Pecilocin Not Annotated Fluperolone Not Annotated Tribromometacresol Not Annotated Dextranomer Not Annotated Pyrrolnitrin Not Annotated Chlormidazole Not Annotated Ticlatone Not Annotated Ethyl hydroxybenzoate Not Annotated Eberconazole Not Annotated Sulbentine Not Annotated Quinisocaine Not Annotated Tacalcitol A vitamin D analog indicated in the treatment of mild to moderate plaque psoriasis. Bromochlorosalicylanilide Not Annotated Decamethoxine Not Annotated Eosin A medication used to disinfect small skin wounds, bug bites, and sores. Halometasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses. Biphenylol Not Annotated Trolamine Trolamine is used as an alkalizing agent, surfactant, and counter-ion in cosmetic and pharmaceutical formulations . It is not considered to be an active pharmacological ingredient and so has no... Mercuric chloride Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a... Ibacitabine Not Annotated Iodoform No approved therapeutic indications. Xenysalate Not Annotated Potassium permanganate Not Annotated Phenylmercuric borate Not Annotated Gamolenic acid An ingredient found in a variety of nutritional products. Fluclorolone Not Annotated Dimazole Dimazole (diamthazole) is an antifungal. It was withdrawn in Franch in 1972 due to neuropsychiatric reactions. Fluticasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD. Vitamin A A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. Fluconazole A triazole antifungal used to treat various fungal infections including candidiasis. Erythromycin A macrolide antibiotic used to treat and prevent a variety of bacterial infections. Oxiconazole A topical antifungal used to treat a variety of dermatophyte infections. Dapsone A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis. Clotrimazole A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Clemastine An antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis. Penciclovir A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. Fluorometholone An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye. Nitrofural A topical antibacterial for the prevention and treatment of bacterial infections of the skin. Minoxidil An antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage. Gentian violet cation An antiseptic violet dye used to prevent various infections, including fungal and bacterial infections. Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Framycetin An aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus. Alitretinoin A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. Cinchocaine An anesthetic used for local or regional anesthesia. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Fluocinolone acetonide A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye. Oxytetracycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Triamcinolone A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Nystatin A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Flumethasone A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions. Thiabendazole A benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections. Tetracycline An antibiotic used to treat a wide variety of susceptible infections. Acyclovir A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body. Natamycin A macrolide antifungal used to treat fungal infections of the eye. Tacrolimus A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. Ethanol For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical... Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Salicylic acid An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Methylprednisolone A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. Neomycin An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. Cromoglicic acid A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions. Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. Fluocinonide A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions. Promethazine A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. Benzocaine A topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations. Flucytosine An antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus. Econazole A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor. Sertaconazole A topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients. Finasteride An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase. Rifaximin A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Pantothenic acid A vitamin B5 found in various nutritional supplements. Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Phenol An antiseptic and disinfectant used in a variety of settings. Dequalinium A quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat that has been studied in the treatment of vaginal candidiasis. Bithionol Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the... Clioquinol An antifungal cream used to treat a variety of fungal infections. Thenalidine Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia. Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Eflornithine A medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin. Mafenide An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Povidone-iodine A topical antiseptic agent used for the treatment and prevention of infection in wounds. Chloropyramine For the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Isothipendyl A 1st generation histamine H1 antagonist primarily applied topically as an antipruritic. Isoconazole An imidazole antifungal used for superficial skin and vaginal infections. Fluocortolone A glucocorticoid used topically for localized skin reactions and also orally for systemic use. Tetracaine A local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. Dexpanthenol An alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). Cetylpyridinium A compound used to reduce plaque and gingivitis, as well as whiten teeth. Hydrogen peroxide A compound used as a disinfectant and sterilizer. Benzalkonium An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products. Benzethonium A medication used as to clean hands and clean minor cuts and scrapes. Calcium gluconate An ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning. Oxyquinoline A medication used in combination with other medications to restore vaginal pH. Thonzylamine Thozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms [FDA Label]. It is typically a part of combination over the counter... Octenidine An antiseptic agent used topically, on mucous membranes, and prior to surgery. Clobetasone A corticosteroid used to treat dry eyes, eczema, and dermatitis. Chlorquinaldol Chlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment... Mesulfen Not Annotated Flutrimazole A topical antifungal used to treat pityriasis capitis and seborrheic dermatitis. Bamipine An H1 antihistamine used topically to relieve mild to moderate symptoms associated with insect bites. Policresulen Not Annotated Tyrothricin A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections. Dibrompropamidine Not Annotated Benzoxonium An antiseptic indicated in skin disinfection and prevention of infections. Metandienone An anabolic steroid indicated for appetite stimulation in patients with anorexia. Mepartricin A medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis. Omoconazole Not Annotated Mometasone furoate A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. Hydrocortisone butyrate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. Lithium succinate Not Available Hydrocortisone aceponate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone probutate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Methylprednisolone aceponate A corticosteroid indicated in the treatment of corticosteroid-responsive dermatoses. Tosylchloramide A chlorinated disinfectant of the genitals and injured skin. Urea A keratolytic emollient used to treat hyperkeratotic lesions and moisturize the skin. Propyl alcohol An antiseptic and disinfectant used in a variety of clinical and domestic settings. Hexamidine An antiseptic drug used for dermatomycoses and superficial bacterial infections alone or in combination with clotrimazole. Didecyldimethylammonium A disinfectant and microbicidal agent used in a variety of products. Methyl aminolevulinate A porphyrin precursor used to treat non-hyperkeratotic, non-pigmented actinic keratosis of the face and scalp. Doxepin A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Deoxycholic acid A cytolytic agent injected subcutaneously to improve the appearance submental fat. Crisaborole A non-steroidal topical medication used for the treatment of mild-moderate atopic dermatitis. Tavaborole An antifungal agent used to treat onychomycosis, a fungal infection of the nail. Dupilumab A monoclonal antibody used to treat moderate to severe atopic dermatitis, asthma, and nasal polyps accompanied by chronic rhinosinusitis in adolescents and adults. Trifarotene A topical retinoid indicated for the treatment of acne vulgaris. Ozenoxacin A quinolone antibiotic used to treat impetigo caused by susceptible bacteria. Dihematoporphyrin ether Dihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma). Etanercept A protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis. Citraconic acid Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. Octisalate Ingredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer. Homosalate As ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer. Ichthammol Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed... Ixekizumab A monoclonal antibody used to treat moderate to severe plaque psoriasis. Brodalumab A monoclonal antibody used to treat moderate to severe plaque psoriasis. Sarecycline A tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris. Fezakinumab Fezakinumab has been used in trials studying the treatment of Atopic Dermatitis and Rheumatoid Arthritis. Aluminum chloride Indicated for the control of minor hemorrhage during dental restorative procedures. Indicated to reduce underarm perspiration. Levomenthol An organic compound used to treat mild to moderate muscle and joint pain. Glycopyrronium An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. Rifamycin An antibacterial used to treat traveler's diarrhea. Calcium monoethylfumarate Not Annotated Zinc monoethylfumarate Not Annotated Hemoporfin A porphyrin derivative combined with vitamin B12 for the treatment of asthenia. Cadexomer iodine Not Annotated Deucravacitinib Deucravacitinib is under investigation in clinical trial NCT04772079 (A Study to Evaluate the Drug Levels, Efficacy and Safety of BMS-986165 in Adolescent Participants With Moderate to Severe Plaque Psoriasis).
- Drugs & Drug Targets