Coagulation factor VII

BE0000333ProteinHumansF7

Initiates the extrinsic pathway of blood coagulation. It is acted on by 28 drugs in DrugBank.

Gene name
F7
UniProtKB entry
P08709Swiss-Prot
Cellular location
Secreted
Residues / weight
466 residues · 51,593 Da
Also known as
3.4.21.21 · Proconvertin · Serum prothrombin conversion accelerator · SPCA

Resolves to

Protein
UniProtP08709UniProt nameFA7_HUMAN
Gene
HGNCHGNC:3544NCBI Gene2155GenBank182801GeneCardsF7
Pharmacology
IUPHAR/GtoPdb2363KEGGhsa:2155
Structure
PDB1BF9PDB1CVWPDB1DAN
Drugs

What you can answer from here — as of September 07, 2019

28DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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18GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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94+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Coagulation factor VII, how selective are they, and which programs against it are still in active trials?

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