Steroids
- Name
- Steroids
- Accession Number
- DBCAT000309
- Description
A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
- Drugs
Drug Drug Description 1-Testosterone 1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring. 16-Bromoepiandrosterone Investigated for use/treatment in cystic fibrosis, HIV infection, hepatitis (viral, B), and malaria. 19-norandrostenedione The claim that supplemental 19-norandrostenedione has anabolic effects is unsubstantiated. 1alpha-Hydroxyvitamin D5 1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity. 1alpha,24S-Dihydroxyvitamin D2 Investigated for use/treatment in parathyroid disorders. 2-Hydroxyestradiol 2-Hydroxyestradiol is classified as an endogenous steroid, catechol estrogen, and metabolite of estradiol. It is also a positional isomer of estriol. 2-Methoxyestradiol For the treatment of breast cancer and inflammatory diseases such as rheumatoid arthritis. 20-hydroxycholesterol Not Available 20-Hydroxyecdysone Not Annotated 24-Homo-1,25-dihydroxyvitamin D3 24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue. 24,25-Dihydroxycholecalciferol Not Annotated 25-Hydroxycholesterol Not Available 4-Hydroxytestosterone 4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by... 5-androstenedione 5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its... 5alpha-androstane-3beta,17alpha-diol 5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite of testosterone with androgenic activity. It has been implicated as a regulator of gonadotropin secretion. 7beta-hydroxycholesterol Not Available Abiraterone An antiandrogen used in the treatment of metastatic castration-resistant prostate cancer and metastatic high-risk castration-sensitive prostate cancer. Acetyldigitoxin Used for fast digitalization in congestive heart failure. Acetyldigoxin Not Annotated Acrihellin Acrihellin is a small molecule drug. Acrihellin has a monoisotopic molecular weight of 498.26 Da. Actodigin Actodigin is a small molecule drug. Actodigin has a monoisotopic molecular weight of 536.3 Da. Afimoxifene For the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring. Alclometasone A topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses. Aldosterone A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. Alfacalcidol A vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure, as well as some types of rickets and osteomalacia. Alfaxalone Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use... Algestone Not Available Algestone acetophenide A progestin indicated in combination with an estrogen as an injectable contraceptive. Allylestrenol A steroid used to prevent premature labour in pregnant women. Altrenogest Altrenogest, also known as allyltrenbolone, is a steroidal progestin that is widely used in veterinary medicine to suppress estrus in animals. Amafolone Amafolone is a small molecule drug. Amafolone has a monoisotopic molecular weight of 305.24 Da. Amcinonide A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses. Anagestone Anagestone is a small molecule drug. Anagestone has a monoisotopic molecular weight of 330.26 Da. Androstenediol Androstenediol is an intermediate in testosterone biosynthesis, found in the testis or the adrenal glands. Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted... Androstenedione A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as... Anecortave Anecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension). Anecortave acetate Investigated for use/treatment in glaucoma and macular degeneration. Apoptone Investigated for use/treatment in cancer/tumors (unspecified). Aramchol Aramchol has been used in trials studying the treatment of HIV, Gallstones, Fatty Liver, Metabolic Syndrome, and Nonalcoholic Steatohepatitis, among others. Asoprisnil Investigated for use/treatment in uterine fibroids. Atamestane Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent. Azacosterol Azacosterol is a small molecule drug. Azacosterol has a monoisotopic molecular weight of 388.35 Da. Azastene Azastene is a small molecule drug. Azastene has a monoisotopic molecular weight of 355.25 Da. Bamet-UD2 Bamet-UD2 is a novel bile acid-platinum derivative. Beclomethasone 17-monopropionate An ester of beclomethasone. Beclomethasone dipropionate An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. Becocalcidiol For topical treatment of psoriasis and psoriatic disorders. Bendacort Not Annotated beta-Sitosterol Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity. Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. Betamethasone phosphate A fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions. Bezisterim For the treatment of rheumatoid arthritis and type 2 diabetes. Bolandiol Not Available Bolasterone Not Available Boldenone Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through... Boldenone undecylenate Not Annotated Boldione Not Available Brexanolone Brexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label] . Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Bufogenin Bufogenin is a small molecule drug. Bufogenin has a monoisotopic molecular weight of 384.23 Da. Calcifediol An active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients. Calcipotriol A topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis. Calcitriol An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Calusterone An anabolic steroid which can theoretically aid in restauration and buildup of certain tissues, especially muscle. It is similar to synthetic testosterone and is still in early investigation. It was... Canrenoic acid An aldosterone antagonist used in primary hyperaldosteronism and other disorders related to aberrant aldosterone levels. Canrenone An antimineralocorticoid and active metabolite of spironolactone used in the treatment of primary hyperaldosteronism and edematous states caused by secondary hyperaldosteronism (e.g. heart failure). Caprospinol Alzheimer's Disease Chenodeoxycholic acid A bile acid used for the treatment of primary biliary cirrhosis. Chlormadinone A progestin indicated in combination with an estrogen for oral combined hormonal contraceptive therapy. Chlormadinone acetate A progestin indicated in combination with an estrogen for birth control. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Cholesterol The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Cholesterol sulfate Component of human seminal plasma & spermatozoa. Cholesteryl chloride Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol. It is presented as a liquid crystal that forms clockwise liquid crystals. Cholesteryl Linoleate Not Available Cholesteryl oleate Not Annotated Cholic Acid A bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. Ciclesonide A glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents. cis-Diamminechlorocholylglycinateplatinum(II) Not Annotated Clascoterone An androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older. Clobetasol Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. Clobetasol propionate A corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis. Clobetasone A corticosteroid used to treat dry eyes, eczema, and dermatitis. Clocortolone A corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp. Clocortolone acetate Not Annotated Clogestone Clogestone is a small molecule drug. Clogestone has a monoisotopic molecular weight of 364.18 Da. Cloprednol A glucocorticoid indicated in the treatment of arthritis and asthma. Clostebol Not Available Clostebol acetate A steroid combined with neomycin in topical formulations for the treatment of minor skin wounds. Colestilan chloride Colestilan is an ingredient in the EMA-withdrawn product BindRen. Corticosterone An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) Corticotropin A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Cortisone A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to... Cortisone acetate A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones. Cortivazol Cortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)). Cymarin Not Annotated Cyproterone acetate A steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer Danazol A synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts. Deflazacort A corticosteroid used to treat Duchenne muscular dystrophy. Dehydrocholic acid No approved therapeutic indications. Demegestone Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued. Deoxycholic acid A cytolytic agent injected subcutaneously to improve the appearance submental fat. Deslanoside For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure. Desogestrel A synthetic progestin used in contraception, often in combination with ethinyl estradiol. Desonide A topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Desoximetasone A glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Desoxycorticosterone acetate Not Annotated Desoxycorticosterone pivalate Examined for treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis. Currently only approved in treating cats and dogs for the treatment of... Desoxycortone Not Annotated Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. Dexamethasone acetate Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. Developed in 1957, dexamethasone is... Dexamethasone isonicotinate Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention. Dexamethasone metasulfobenzoate An ophthalmic and auricular corticosteroid used with antibiotics for the treatment of otitis externa, blepharitis, and other inflammatory eye conditions. Dexamethasone palmitate Dexamethasone palmitate is under investigation in clinical trial NCT05693467 (Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery). Dicirenone Dicirenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Dicirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. Dicirenone has... Dienogest An oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol. Diflorasone A topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort. Difluocortolone A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis. Difluprednate A topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery. Digitoxigenin Digitoxigenin is a cardenolide which is the aglycon of digitoxin. Digitoxin A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. Digoxigenin Digoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh. Dihydrotachysterol A synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3. Doxercalciferol A synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis. Drospirenone A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions. Drostanolone Drostanolone (also known as dromostanolone) is a potent synthetic androgenic anabolic steroid similar to testosterone. Drostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy. Drostanolone propionate For use in females, for palliation of androgenresponsive recurrent mammary cancer in women who are more than one year but less than five years postmenopausal. Dutasteride An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase. Dydrogesterone A synthetic progesterone for menstrual cycle regulation, infertility treatment, prevention of miscarriage, and other conditions. Ecalcidene Ecalcidene is a small molecule drug. Ecalcidene has a monoisotopic molecular weight of 455.34 Da. Edogestrone Edogestrone is a small molecule drug. Edogestrone has a monoisotopic molecular weight of 430.27 Da. Eldecalcitol Investigated for use/treatment in osteoporosis. Elocalcitol Investigated for use/treatment in benign prostatic hyperplasia, urinary incontinence, prostate disorders, and infertility. Eltanolone Eltanolone is under investigation in clinical trial NCT02603926 (Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone). EM-1745 Not Available ENMD-1198 Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors. Epimestrol Not Annotated Epitestosterone Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone... Epitiostanol Epitiostanol is a small molecule drug. Epitiostanol has a monoisotopic molecular weight of 306.2 Da. Eplerenone An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. Epristeride Epristeride is a small molecule drug. The usage of the INN stem '-steride' in the name indicates that Epristeride is a androgen/anabolic steroid. Epristeride has a monoisotopic molecular weight of... Equilenin Equilenin is an estrogenic steroid produced by horses. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine... Equilin For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and... Ergosterol A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS... Escherichia coli strain Nissle 1917 An oral bacterial suspension indicated to treat diarrhea in patients up to 12 years old and tube fed children. Estetrol An estrogen used in combination with drospirenone for oral contraception. Estradiol An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. Estradiol benzoate An estrogen indicated in combination with progesterone for the treatment of irregular menstruation. Estradiol cypionate An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism. Estradiol dienanthate An estrogen used in some combined hormonal oral contraceptives. Estradiol sulfamate Investigated for use/treatment in endometriosis. Estradiol valerate An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception. Estramustine An antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting. Estramustine phosphate A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties. Estrane-3,17-dione Estrane-3,17-dione is a potent inhibitor of isomerase. Estrapronicate Estrapronicate is a small molecule drug. Estrapronicate has a monoisotopic molecular weight of 433.23 Da. Estriol A weak estrogen used to treat vaginal dryness and estrogen deficiency conditions, such as vaginitis and vulvar itching. Estriol succinate Estriol succinate is a small molecule drug. Estriol succinate has a monoisotopic molecular weight of 488.2 Da. Estrone An estrogen used to treat perimenopausal and postmenopausal symptoms. Estrone sulfate An estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders. Ethinylestradiol An estradiol used as a contraceptive. Ethylestrenol An anabolic steroid with some progestational activity and little androgenic effect. [PubChem] Ethynerone Ethynerone is a small molecule drug. Ethynerone has a monoisotopic molecular weight of 330.14 Da. Ethynodiol diacetate An oral contraceptive used to prevent pregnancy. Etonogestrel A long-acting synthetic derived progestin contraceptive used in various devices such as contraceptive rings and intradermal implants. Etynodiol Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers... Exemestane An aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen. Falecalcitriol Falecalcitriol is a small molecule drug. Falecalcitriol has a monoisotopic molecular weight of 524.27 Da. Finasteride An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase. Fluasterone Investigated for use/treatment in psoriasis and psoriatic disorders, hyperlipidemia, metabolic disease, cancer/tumors (unspecified), and obesity. Fluclorolone Not Annotated Fluclorolone acetonide Fluclorolone acetonide (INN) or flucloronide (USAN) is a topical corticosteroid. It is marketed under the brand names Cutanit and Topicon. Fludrocortisone A mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome. Flumedroxone Not Annotated Flumethasone A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions. Flunisolide An inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma. Flunisolide acetate Not Annotated Fluocinolone Fluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral Lichen Planus, Macular Degeneration, and Choroidal Neovascularization. Fluocinolone acetonide A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye. Fluocinonide A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions. Fluocortin Fluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain . Fluocortolone A glucocorticoid used topically for localized skin reactions and also orally for systemic use. Fluocortolone caproate A corticosteroid indicated in the treatment of hemorrhoids, anal fissures, and corticosteroid-responsive dermatoses. Fluocortolone pivalate A corticosteroid used to treat corticosteroid-responsive dermatoses and hemorrhoids. Fluoroestradiol F-18 A radiolabeled analog of estradiol used as a contrast agent in the PET imaging of estrogen receptor-positive breast cancer lesions. Fluorometholone An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye. Fluoxymesterone A synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women. Fluperolone Not Annotated Fluprednidene Fluprednidene is a corticosteroid. Fluprednidene acetate A corticosteroid indicated in the treatment of corticosteroid-responsive dermatoses. Fluprednisolone A synthetic glucocorticoid with anti-inflammatory properties. Flurandrenolide A corticosteroid used to treat corticosteroid-responsive dermatoses. Fluticasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD. Fluticasone furoate An inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis. Fluticasone propionate A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. Formebolone No approved indications. Studied experimentally as a treatment for non-pituitary growth retardation. Formestane For the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formocortal Not Annotated Fulvestrant An estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-. Furazabol Not Available Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Galeterone Galeterone has been used in trials studying the treatment of Prostate Cancer. Ganaxolone A neuroactive steroid GABA-A receptor modulator used for the treatment of seizures associated with CDKL5 deficiency disorder (CDD). Gestodene Gestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol... Gestonorone caproate Not Annotated Gestrinone Endometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime . Gitoformate Not Annotated Glycochenodeoxycholic Acid A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed.... Glycocholic acid The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Halcinonide A corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Halometasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses. HE-2200 Investigated for use/treatment in adverse effects (chemotherapy), hyperlipidemia, autoimmune diseases, and hepatitis (viral, B). Hydrocortisone A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. Hydrocortisone aceponate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone acetate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis. Hydrocortisone butyrate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone cypionate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone phosphate A corticosteroid used to treat congenital adrenal hyperplasia, for emergency asthma treatment, hypersensitivity, and inflammation. Hydrocortisone probutate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone succinate A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Hydrocortisone valerate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydroxydione Hydroxydione (Viadril) is a neuroactive steroid used as a general anesthetic. Hydroxyprogesterone Not Annotated Hydroxyprogesterone caproate A synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. Hyodeoxycholic Acid Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia. ICI-164384 Not Available Ifidancitinib Ifidancitinib is under investigation in clinical trial NCT03585296 (A Study of ATI-502 Topical Solution for the Treatment of Atopic Dermatitis). Inecalcitol Investigated for use/treatment in prostate cancer, psoriasis and hyperparathyroidism. Inotodiol Not Annotated Iodine (131I) norcholesterol A radioiodine-labeled cholesterol analogue that accumulates in areas where steroid hormones are produced and is used in certain diagnostic procedures. Isoflupredone Not Annotated Isoflupredone acetate Not Annotated Istaroxime Investigated for use/treatment in heart disease. KB3305 Investigated for use/treatment in diabetes mellitus type 2. Lanatoside C Not Annotated Lanosterol Not Available Larsucosterol Not Annotated Levonorgestrel A progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives. Lexacalcitol Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known... Lonaprisan Lonaprisan is under investigation in clinical trial NCT00555919 (ZK 230211 in Postmenopausal Woman With Metastatic Breast Cancer). Loteprednol A corticosteroid indicated in the treatment of pain and inflammation after cataract surgery. Loteprednol etabonate A corticosteroid used to treat allergic conjunctivitis as well as inflammation and pain after ocular surgery. Lynestrenol A progestin used for contraception and in the treatment of menstrual disorders. Maxacalcitol Not Annotated Mazipredone Mazipredone is a small molecule drug. Mazipredone has a monoisotopic molecular weight of 442.28 Da. Mebolazine Mebolazine is a small molecule drug. Mebolazine has a monoisotopic molecular weight of 632.53 Da. Medrogestone A progestin used as an adjunct to control secondary amenorrhea and dysfunctional bleeding in adolescent and adult females, and treat endometrial shedding in menopausal women. Medroxyprogesterone acetate A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty. Medrysone A topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions. Megestrol Not Annotated Megestrol acetate A progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy. Melengestrol Melengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals. Melengestrol acetate A 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus. Mepitiostane Mepitiostane is a small molecule drug. Mepitiostane has a monoisotopic molecular weight of 404.27 Da. Meprednisone Not Annotated Mespirenone Mespirenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Mespirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. Mespirenone has... Mesterolone An anabolic steroid indicated in the treatment of low testosterone, hypogonadism, oligozoospermia, and Leydig cell failure. Mestranol A synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding. Metandienone An anabolic steroid indicated for appetite stimulation in patients with anorexia. Metenolone An anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes. Methylestrenolone Not Annotated Methylhexaneamine Not Annotated Methylprednisolone A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. Methylprednisolone aceponate A corticosteroid indicated in the treatment of corticosteroid-responsive dermatoses. Methylprednisolone hemisuccinate A water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Methyltestosterone A synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females. Metildigoxin A digitalis glycoside indicated in the treatment of acute and chronic heart failure. Metribolone A synthetic non-aromatizable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate... Mibolerone Mibolerone is a potent anabolic steroid which is both higher affinity and more selective for the androgen receptor than metribolone. Mifepristone A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. Minamestane Minamestane is a small molecule drug. The usage of the INN stem '-mestane' in the name indicates that Minamestane is a aromatase inhibitor. Minamestane has a monoisotopic molecular weight of... Minaxolone Minaxolone is a small molecule drug. Minaxolone has a monoisotopic molecular weight of 405.32 Da. MK-0773 MK-0773 is under investigation in clinical trial NCT00529659 (A Study of the Safety and Efficacy of MK-0773 in Women With Sarcopenia (Loss of Muscle Mass)(mk-0773-005)). MK-4541 MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor. Mometasone A corticosteroid with no indications. Mometasone furoate A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. Moxestrol Not Annotated Nandrolone An anabolic steroid indicated to increase bone density and muscle mass in patients with osteoporosis. Nandrolone decanoate An anabolic steroid indicated for the management of the anemia of renal insufficiency by increasing hemoglobin and red cell mass. Nandrolone phenpropionate For the treatment of refractory deficient red cell production anemias, breast carcinoma, hereditary angioedema, antithrombin III deficiency, fibrinogen excess, growth failure and Turner's syndrome. It is also indicated in the... NCX 1015 Investigated for use/treatment in arthritis and arthritic pain and inflammatory bowel disease. NCX 1022 Investigated for use/treatment in atopic dermatitis. NCX-1000 NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure). Nivazol Nivazol is a small molecule drug. Nivazol has a monoisotopic molecular weight of 430.24 Da. Nomegestrol Nomegestrol is an ingredient in the EMA-authorised product Zoely. Nomegestrol acetate Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders. Nordinone Nordinone is a small molecule drug. Nordinone has a monoisotopic molecular weight of 300.21 Da. Norelgestromin A progestin used as the progestational component of a transdermal combined hormonal contraceptive, preventing pregnancy primarily through suppression of ovulation. Norethandrolone Norethandrolone is under investigation in clinical trial NCT00700544 (Treatment Outcome in Elderly Patients). Norethindrone enanthate A synthetic progestogen indicated for contraceptive therapy. Norethisterone A synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis. Norethynodrel A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it... Norgesterone Norgesterone is a small molecule drug. The usage of the INN stem '-terone' in the name indicates that Norgesterone is a antiandrogen. Norgesterone has a monoisotopic molecular weight of 300.21... Norgestimate A progesterone used as a contraceptive and to treat acne vulgaris. Norgestomet Norgestomet, also known as 11β-methyl-17-hydroxy-19-norprogesterone acetate, is a steroidal progestin used in veterinary medicine to control estrus and ovulation in cattle. Norgestrel A progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women. Norgestrienone Not Annotated norUrsodeoxycholic acid norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid vs Placebo in PSC). Oleandrin Oleandrin has been used in trials studying the treatment of Lung Cancer and Chemotherapeutic Agent Toxicity. Oleoyl-estrone For the treatment of obesity. Olesoxime Investigated for use/treatment in neurologic disorders. Onapristone Onapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 Line of... ORG-31710 ORG-31710 is a progestational hormone antagonist. Ouabain For the treatment of atrial fibrillation and flutter and heart failure Ox bile extract Not Annotated Oxabolone cipionate Used as a performance enhancing drug illicitly in athletes. Oxandrolone An androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis. Oxymetholone An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias. Pancuronium A neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Paramethasone For the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary... Paramethasone acetate Not Annotated Paricalcitol A vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease. Peruvoside Not Annotated Plomestane Plomestane is a small molecule drug. The usage of the INN stem '-mestane' in the name indicates that Plomestane is a aromatase inhibitor. Plomestane has a monoisotopic molecular weight of... Polyestradiol phosphate Polymeric phosphoric acid ester of estradiol. Posovolone Posovolone is a small molecule drug. Posovolone has a monoisotopic molecular weight of 428.3 Da. Prasterone A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. Prasterone enantate An estrogen indicated for hormone replacement therapy in postmenopausal women. Prasterone sulfate Investigated for use/treatment in asthma and burns and burn infections. Prednicarbate A medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions. Prednimustine Prednimustine has been used in trials studying the treatment of Lymphoma. Prednisolone A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. Prednisolone acetate A glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions. Prednisolone hemisuccinate A corticosteroid indicated in the treatment of anaphylaxis, asthma, edema, organ rejection, and other indications. Prednisolone phosphate A corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions. Prednisolone tebutate Not Annotated Prednisone A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. Prednisone acetate Not Annotated Prednylidene Prednylidene is an experimental systemic glucocorticoid. Pregnenolone A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. Previtamin D(3) Not Annotated Progesterone A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. Promegestone Not Annotated Promestriene A synthetic estrogen applied topically for the treatment of vulvovaginal atrophic symptoms and to speed wound healing following vulvovaginal surgery or trauma (e.g. post-partum). Proscillaridin Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,... Quinbolone Not Annotated Quinestrol Used in hormone replacement therapy, treating symptoms of menopause such as hot flashes. Also used to treat breast and prostate cancer. Quingestanol Not Annotated Quingestanol acetate Not Annotated Rapacuronium A nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures. Rimexolone A glucocorticoid used to treat inflammation of the eye. RO-23-7553 Not Annotated Rocuronium A vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery. Rostafuroxin Rostafuroxin has been used in trials studying the treatment of Essential Hypertension. Roxibolone Roxibolone is a small molecule drug. Roxibolone has a monoisotopic molecular weight of 360.19 Da. Ruscogenin An anti-inflammatory steroid used in combination with local anesthetics for the treatment of hemorrhoids and for local anesthesia. Sarsagenin Not Annotated Segesterone acetate Segesterone acetate in combination with ethinyl estradiol is indicated for use by females of reproductive potential to prevent pregnancy as a combination hormonal contraceptive (CHC). It induces contraception for thirteen... Seocalcitol Not Available Sepranolone Sepranolone has been investigated for the treatment of Premenstrual Dysphoric Disorder. Sitogluside Sitogluside is a small molecule drug. Sitogluside has a monoisotopic molecular weight of 576.44 Da. Smilagenin Investigated for use/treatment in alzheimer's disease, parkinson's disease and other neurodegenerative diseases. Sonolisib Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid Tumors, Advanced BRAF-mutant Cancers, and Non Small Cell Lung Cancer (NSCLC), among others. Soy sterol Not Annotated Spironolactone An aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism. Squalamine Investigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration. Stanolone A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure... Stanozolol An anabolic steroid used to manage hereditary angioedema. Tacalcitol A vitamin D analog indicated in the treatment of mild to moderate plaque psoriasis. Taurochenodeoxycholic acid Taurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy. Taurocholic acid The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats... Telapristone acetate For the treatment of uterine fibroids and endometriosis. Testolactone A medication used to treat advanced breast cancer. Testosterone A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. Testosterone cypionate An androgen used to treat low or absent testosterone. Testosterone decanoate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone enantate benzilic acid hydrazone Not Annotated Testosterone enanthate An androgen used to treat low or absent testosterone. Testosterone isocaproate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone phenylpropionate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone propionate A slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles. Testosterone succinate Not Available Testosterone undecanoate An androgen indicated for testosterone replacement therapy in adult males with primary hypogonadism and hypogonadotropic hypogonadism. Tetrahydrogestrinone Not Available Tibolone For the relief of post-menopausal symptoms and for the prevention of osteoporosis . Tiomesterone Tiomesterone is a small molecule drug. The usage of the INN stem '-terone' in the name indicates that Tiomesterone is a antiandrogen. Tiomesterone has a monoisotopic molecular weight of 450.19... Tipredane Tipredane is a small molecule drug. Tipredane has a monoisotopic molecular weight of 410.17 Da. Tirilazad Tirilazad has been used in trials studying the treatment of Spinal Cord Injury. Tixocortol A corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis. Trenbolone Trenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite. To increase its effective half-life, trenbolone is administered as a prodrug... Trenbolone acetate Not Annotated Trestolone Investigated for use/treatment in contraception and male hormonal deficiencies/abnormalities. Trestolone acetate Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate... Triamcinolone A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. Trilostane Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Trimegestone Trimegestone has been used in trials studying the treatment of Postmenopause. TRO40303 TRO40303 is under investigation in clinical trial NCT01374321 (Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction). Trodusquemine Investigated for use/treatment in obesity and diabetes mellitus type 2. Turosteride Turosteride is a small molecule drug. The usage of the INN stem '-steride' in the name indicates that Turosteride is a androgen/anabolic steroid. Turosteride has a monoisotopic molecular weight of... Ulipristal A selective progesterone receptor modulator used for emergency contraception after unprotected intercourse or in a situation where a planned method of contraception has failed. Ulobetasol A lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. UniPR129 Not Annotated Ursodeoxycholic acid A bile acid used for the treatment of primary biliary cirrhosis (PBC). Vamorolone A synthetic glucocorticoid used as an anti-inflammatory and immunosuppressant in the management of Duchenne muscular dystrophy (DMD). Vecuronium A nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures. Vitamin D An ingredient found in a variety of supplements and vitamins. Wortmannin Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks). Zanoterone Zanoterone is a small molecule drug. The usage of the INN stem '-terone' in the name indicates that Zanoterone is a antiandrogen. Zanoterone has a monoisotopic molecular weight of 416.21... Zuranolone A neuroactive steroid drug used to treat postpartum depression - Drugs & Drug Targets