- Nitro Compounds
- Accession Number
Compounds having the nitro group, -NO2, attached to carbon. When attached to nitrogen they are nitramines and attached to oxygen they are NITRATES.
Drug Drug Description Tolcapone A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. Nitrofural A topical antibacterial for the prevention and treatment of bacterial infections of the skin. Nitrofurantoin An antibiotic used to treat urinary tract infections. Nitroglycerin A nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures. Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Pretomanid Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis. Chloramphenicol succinate A broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains. Nifurtimox An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). Fexinidazole An orally bioavailable 2-substituted 5-nitroimidazole used to treat early- and late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense. Secnidazole A nitroimidazole antibiotic used to treat bacterial vaginosis. Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Furazolidone A drug for the treatment of infectious diarrhea. Tinidazole A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. Nitroxoline Nitroxoline is an antibiotic agent. 1,3-Dinitrobenzene Not Available Picric acid Used as antiseptic, astringent, and stimulant for epitheliazation. 4-Nitrophenyl Phosphate Not Available P-Nitrophenol Not Available 2,4-Dinitrophenol A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman,... Evofosfamide Investigated for use/treatment in solid tumors. Bromamphenicol Not Available Thiamphenicol A semisynthetic derivative of chloramphenicol with a broad spectrum of antibacterial activity. Efonidipine For the treatment of hypertension. Manidipine A dihydropyridine calcium channel blocker used to treat hypertension. Florfenicol Florfenicol is a fluorinated synthetic analog of thiamphenicol. Nifurpirinol Not Annotated Delamanid An antibiotic used to treat multidrug resistant tuberculosis. Misonidazole Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole). Dinitrochlorobenzene Dinitrochlorobenzene has been used in trials studying the treatment of HIV Infections. Benznidazole A trypanocidal agent used to treat Chagas disease. Nimorazole Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others. Pimonidazole Pimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer. Etanidazole Etanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others. Ornidazole A nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis. Azidamfenicol Not Annotated Nifurzide Not Annotated Azanidazole Not Annotated Furazidin Not Annotated Clefamide Not Annotated Nifuratel A nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections. Nifurtoinol Not Annotated Nifuroxazide An antibiotic indicated in the treatment of susceptible gastrointestinal infections. NS-398 NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. Chloramphenicol palmitate Not Annotated Morinidazole Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis). Fluoroazomycin arabinoside F-18 Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer). Metronidazole benzoate Not Annotated Furaltadone Indicated in combination with other drugs for the treatment of otitis media and externa.
- Drugs & Drug Targets