Biological Products
- Name
- Biological Products
- Accession Number
- DBCAT000108
- Description
Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.
- Drugs
Drug Drug Description Menotropins A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Ethiodized oil A contrast agent used in imaging procedures. Camphor A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed. Ricinoleic acid Not Available Choline alfoscerate A natural choline that is used to manage declining cognitive function associated with neurodegenerative and vascular diseases. BZL101 Investigated for use/treatment in breast cancer. Andrographolide Investigated for use/treatment in ulcerative colitis. LLL-3348 Investigated for use/treatment in psoriasis and psoriatic disorders. Podophyllin A cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata). Soybean oil An oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency. Safflower oil No approved therapeutic indications. Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Olive oil In a clinical context, olive oil is used as a source of calories and fatty acids in patients requiring parenteral nutrition. A formulation called Clinolipid, comprising olive oil and soybean... Plantago seed An ingredient used in a variety of natural health products. Castor oil An ingredient used in a variety of natural health products. Opium A medication used to treat moderate to severe pain. Capsicum oleoresin A medication used to treat minor aches and pains of muscles and joints. Pectin Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary... Sesame oil Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic... Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Tea tree oil Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications. Benzoin resin A compound used to protect small wounds or canker sores. Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Rice bran oil Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It... Clove oil Clove oil is primarily indicated in conditions like colic, flatulence, and toothache . Linseed oil Linseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic... Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Sennosides A laxative used to treat constipation. Levomenol Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain... Ipecac An emetic agent used to induce vomiting in poisoning. Peanut oil A compound used to lubricate ear wax, as an emollient, and used in laxatives. Turmeric Turmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Panax notoginseng root Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Meadowfoam seed oil Meadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Argan oil Argan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Tangerine peel Tangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Coconut oil Coconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Sunflower oil Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Nelumbo nucifera flower Nelumbo nucifera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Bergamot oil Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Angelica sinensis root Angelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Forsythia suspensa fruit Forsythia suspensa fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Saw palmetto Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Scutellaria baicalensis root Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Palm oil Palm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Sophora flavescens root Not Annotated Lavender oil Not Annotated Plantago ovata seed A plant extract indicated in the treatment of occasional constipation. Emodin Emodin has been investigated for the treatment of Polycystic Kidney. Ginkgo biloba A herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders. Etanercept A protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Adalimumab A monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Eucalyptus oil An ingredient used in a variety of natural health products. Alloin Not Annotated Frangula purshiana bark Not Annotated Onasemnogene abeparvovec A gene therapy used to treat neonatal and infant patients with spinal muscular atrophy caused by bi-allelic mutations in the survival motor neuron 1 (SMN1) gene. beta-Apopicropodophyllin beta-Apopicropodophyllin is a component of the freshwater plant Micranthemum umbrosum. Maritime pine extract A plant extract in nutritional supplements for healthy hair, skin, and nails. Lecithin Fatty substances commonly found in nutritional supplements. Hawthorn leaf with flower Not Annotated Cajuput oil An ingredient used in topical products for mild analgesia. Wheat germ oil Not Annotated Citronella oil Not Annotated Vitis vinifera seed Not Annotated Juniper tar Not Annotated Salvia miltiorrhiza root Salvia miltiorrhiza root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Cedar oil An extract from Juniperus virginiana used in allergy testing. Garlic oil Not Annotated Curcuma aromatica root oil Curcuma aromatica root oil is obtained from the roots of Curcuma aromatica, or more commonly called wild tumeric, via steamed distillation. Curcuma aromatica belongs to the family Zingiberaceae. The wild... Jojoba oil Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Rosemary oil Not Annotated Panax ginseng root oil Panax ginseng root oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Panax ginseng fruit Panax ginseng fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Ginseng A herbal supplement used in many health products. Panax ginseng whole Panax ginseng whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Panax quinquefolius whole Panax quinquefolius whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Chorionic Gonadotropin (Human) A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women. Green tea leaf Green tea leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Infliximab A monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Antithymocyte immunoglobulin (rabbit) A purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants. St. John's Wort An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. Ephedra sinica root An alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest. G17DT Immunogen Intended for the treatment of various forms of cancer. INGN 201 Investigated for use/treatment in bladder cancer, brain cancer, breast cancer, esophageal cancer, head and neck cancer, lung cancer, oral cavity cancer, ovarian cancer, and prostate cancer. INGN 225 Investigated for use/treatment in breast cancer, head and neck cancer, and lung cancer. Obiltoxaximab A monoclonal antibody used for prophylaxis or treatment of inhalational anthrax. Rindopepimut Investigated for use/treatment in brain cancer. SRP 299 Investigated for use/treatment in asthma, atopic dermatitis, and pediatric atopic dermatitis indications. TA-NIC Investigated for use/treatment in tobacco dependence. GI-5005 Investigated for use/treatment in hepatitis (viral, C). Vitespen Investigated for use/treatment in kidney cancer, melanoma, renal cell carcinoma, lymphoma (unspecified), colorectal cancer, and brain cancer. TG4010 Investigated for use/treatment in breast cancer, renal cell carcinoma, prostate cancer, and lung cancer. Antilymphocyte immunoglobulin (horse) A primarily IgG immune globulin used to manage allograft rejection in renal transplant patients. Rotavirus vaccine Rotarix is indicated for prevention of rotavirus gastroenteritis caused by G1, G3, G4, and G9 types in infants aged 6-24 weeks [FDA Label]. Rotateq is indicated for the prevention of... Rabies virus inactivated antigen, A Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the... Varicella zoster vaccine (live/attenuated) Zostavax vaccine is indicated for the prevention of herpes zoster (shingles) in immunocompetent adults aged 50 years and older. Varivax vaccine is indicated for active immunization for the prevention of... Phleum pratense pollen An extract from Phleum pratense pollen used in allergy testing. Acacia An extract from Acacia used in allergy testing. Karaya gum An extract from Karaya gum used in allergy testing. Clostridium tetani toxoid antigen (formaldehyde inactivated) Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention... Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) Not Annotated Tragacanth An extract from Tragacanth used in allergy testing. Clove An extract from Clove used in allergy testing. Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated) Not Annotated Yellow fever vaccine Yellow Fever Vaccine is indicated for active immunization for the prevention of yellow fever in persons 9 months of age and older in the following categories: Persons Living in or... Carob An extract from Carob used in allergy testing. Hepatitis A Vaccine An inactivated vaccine against infection with the Hepatitis A virus. Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects... Anthrax vaccine A vaccine indicated for the pre- and post-exposure prophylaxis treatment of diseases caused by exposure to Bacillus anthracis Turpentine A medication used to treat minor aches and pains of muscles and joints. Rosin An extract from Rosin used in allergy testing. Tolu balsam Not Annotated Balsam of Peru Balsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of... Myrrh FDA approved only for use in food. Historically used for indigestion, ulcers, colds, cough, asthma, bronchial congestion, arthritic pain, cancer, leprosy, and syphilis. It is also used orally as a... Human varicella-zoster immune globulin A solution of antibodies used for post exposure prophylaxis of varicella infections in high risk populations, as well as to reduce the severity of infections. Hepatitis B Vaccine (Recombinant) A solution of Hepatitis B surface antigen used to immunize patients against Hepatitis B. Tecemotide Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung. Aviscumine Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy). BCG vaccine A vaccine indicated in the prevention of tuberculosis and the treatment of non-invasive urothelial bladder cancer. Vitex agnus-castus fruit extract A herbal product used to treat an irregular menstrual period, premenstrual symptoms, and mastodynia Horse chestnut A plant extract indicated in the treatment of venous insufficiency and other disorders caused by poor circulation. Valerian A plant used in some non-prescription natural health products. Guar gum Not Annotated Black cohosh A herbal product indicated in the symptomatic treatment of menopause. Typhoid vaccine A vaccine used to prevent typhoid. Bilberry Not Annotated Echinacea purpurea flowering top Not Annotated Echinacea purpurea Not Annotated Centella asiatica Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Calendula officinalis flower Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Rosemary Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Phellinus linteus mycelium Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Rehmannia glutinosa root Rehmannia glutinosa root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Arnica montana Arnica montana is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Eleuthero Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Tribulus terrestris fruit Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Amber Amber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Chamaemelum nobile flower Chamaemelum nobile flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Prunus armeniaca seed Prunus armeniaca seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Arnica montana flower Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Platycodon grandiflorus root Platycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Chamomile Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Milk thistle Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Vibrio cholerae CVD 103-HgR strain live antigen A live, attenuated vaccine indicated for active immunization against disease caused by Vibrio cholerae serogroup O1. Sambucus nigra flower Not Annotated Willow bark Not Annotated Smallpox (Vaccinia) Vaccine, Live The live antigen of the New York City Board of Health strain of Vaccinia is indicated (within the ACAM2000 formulation) for active immunization against smallpox disease in patients determined to... Olea europaea leaf Not Annotated Polygala senega root Not Annotated Dengue tetravalent vaccine, live Not Annotated Belapectin Belapectin is under investigation in clinical trial NCT02575404 (GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients). Pertussis vaccine Pertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy). Yersinia pestis 195/p antigen (formaldehyde inactivated) Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine). Moderna COVID-19 Vaccine An mRNA vaccine for the prevention of COVID-19 caused by the SARS-CoV-2 virus. AstraZeneca COVID-19 Vaccine A two-dose replication-deficient adenovirus vector vaccine used to prevent COVID-19 caused by SARS-CoV-2. INO-4800 INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that... BNT162b1 SARS-CoV-2 Vaccine BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding... Tozinameran An mRNA vaccine for the prevention of COVID-19 caused by the SARS-CoV-2 virus. Anise oil Not Annotated VPM1002 The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. This recombinant... BBIBP-CorV BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in... Nuvaxovid A recombinant spike (S) protein vaccine for the prevention of COVID-19 caused by SARS-CoV-2. IMM-101 IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma[A220013,A220018,A220023]. Studies... Janssen COVID-19 Vaccine An adenovirus-based vaccine used for active immunization against COVID-19 caused by SARS-CoV-2 infection. Senna leaf A stimulant laxative indicated in the treatment of occasional constipation. Bizalimogene ralaplasmid Bizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related Anal or Anal/peri-anal, High Grade... Pidacmeran Pidacmeran is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults). BNT-162A1 BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults). VidPrevtyn Beta A recombinant, adjuvanted DNA vaccine given as a booster dose to prevent COVID-19. EpiVacCorona EpiVacCorona Vaccine, developed by the Vektor State Research Center of Virology and Biotechnology in Russia, is based on peptide-antigens that facilitate immunity to the SARS-CoV-2 virus . It is currently... Gentiana lutea extract A medication used to treat bloating and gas. Pygeum africanum bark A plant extract indicated in the symptomatic treatment of prostatic hypertrophy. Frankincense Not Annotated Paeonia lactiflora root Not Annotated Thyme oil Not Annotated Gastrodia elata whole Not Annotated Birch bark extract A herbal medicinal product used to treat partial thickness wounds. Algenpantucel-L Not Annotated Leuvectin Leuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE). Onamelatucel-L Not Annotated Gemogenovatucel-T Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine. Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2. Gemogenovatucel-T is being... GI-6207 Not Annotated Picibanil Not Annotated Trastuzumab A monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers. Picrotoxin Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates. Liquidambar styraciflua resin Not Annotated Glycyrrhiza glabra Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Ephedra sinica stem Not Annotated Modified vaccinia ankara A live, non-replicating orthopoxvirus vaccine used to prevent smallpox, monkeypox, and other diseases caused by vaccinia virus. SCB-2019 SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The... CoronaVac CoronaVac, previously known as PiCoVacc, is a SARS-CoV-2 purified, inactivated, and adsorbed vaccine candidate developed by SinoVac Biotech Corporation . It was developed by propagating the SARS-CoV-2 CN2 strain inside... CVnCoV Vaccine The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate... BBV152 BBV152 is a vaccine candidate created by the Indian Council of Medical Research (ICMR). The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and... Rocakinogene sifuplasmid Rocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma (GBM)). CoVac-1 Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein . It is... UB-612 The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components . The vaccine... Famtozinameran A component of a bivalent COVID-19 mRNA vaccine encoding the viral spike protein of Omicron variant lineages BA.4 and BA.5. Nix-0699 Not Annotated Tubimod Not Available Remune Not Available Mycobacterium w. Vaccine The Mycobacterium w (M.w) vaccine is a heat-killed suspension derived from a non-pathogenic mycobacterium: mycobacterium indicus pranii. As an immunotherapy, M.w is used against leprosy; the compound also shares antigens... OM85 OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity. mRNA-1345 mRNA-1345 is an investigational RSV vaccine. Modified vaccinia virus Ankara-85A antigen Modified vaccinia virus Ankara-85A antigen is under investigation in clinical trial NCT00953927 (A Study of MVA85A in Healthy Infants). Lapuleucel-t Not Annotated OXB-301 OXB-301 is under investigation in clinical trial NCT00397345 (Trovax Renal Immunotherapy Survival Trial). - Drugs & Drug Targets