This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Tetroxoprim
- DrugBank Accession Number
- DB15976
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Tetroxoprim (DB15976)
- Weight
- Average: 334.376
Monoisotopic: 334.164105204 - Chemical Formula
- C16H22N4O4
- Synonyms
- Tetroxoprim
- Tetroxoprima
- Tetroxoprime
- Tetroxoprimum
- External IDs
- He 781
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- ATC Codes
- J01EE06 — Sulfadiazine and tetroxoprim
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 5R6712AY0K
- CAS number
- 53808-87-0
- InChI Key
- WSWJIZXMAUYHOE-UHFFFAOYSA-N
- InChI
- InChI=1S/C16H22N4O4/c1-21-4-5-24-14-12(22-2)7-10(8-13(14)23-3)6-11-9-19-16(18)20-15(11)17/h7-9H,4-6H2,1-3H3,(H4,17,18,19,20)
- IUPAC Name
- 5-{[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]methyl}pyrimidine-2,4-diamine
- SMILES
- COCCOC1=C(OC)C=C(CC2=C(N)N=C(N)N=C2)C=C1OC
References
- General References
- Not Available
- External Links
- ChemSpider
- 58910
- BindingDB
- 50029760
- 37999
- ChEBI
- 135420
- ChEMBL
- CHEMBL32039
- ZINC
- ZINC000002020087
- Wikipedia
- Tetroxoprim
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.126 mg/mL ALOGPS logP 1.14 ALOGPS logP 1.24 Chemaxon logS -3.4 ALOGPS pKa (Strongest Acidic) 17.33 Chemaxon pKa (Strongest Basic) 7.16 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 114.74 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 92.55 m3·mol-1 Chemaxon Polarizability 34.88 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at December 03, 2020 16:04 / Updated at February 21, 2021 18:55