Antibacterials for Systemic Use
- Name
- Antibacterials for Systemic Use
- Accession Number
- DBCAT002130
- Description
Not Available
- ATC Classification
- Drugs
Drug Drug Description Daptomycin A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus. Azithromycin A macrolide antibiotic used to treat a variety of bacterial infections. Cefotiam A cephalosporin antibiotic used to treat a variety of bacterial infections. Doxycycline A tetracycline antibiotic used to treat a wide variety of bacterial infections. Lymecycline A tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections. Cefmenoxime Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria. Cefmetazole A cephalosporin antibiotic used to treat a variety of bacterial infections. Flucloxacillin A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA). Ertapenem A carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. Piperacillin A penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam susceptible, β-lactamase generating strains of several bacteria. Aztreonam A beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Grepafloxacin A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections. Ampicillin A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. Phenoxymethylpenicillin A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. Cefpiramide For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa. Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others. Trimethoprim An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. Loracarbef Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,... Clomocycline For the treatment and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection;Chronic bronchitis Cefalotin A broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. Enoxacin For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria... Amikacin An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria. Dicloxacillin A penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug. Pefloxacin An antibiotic used to treat a variety of bacterial infections. Cefotaxime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Vancomycin A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. Cefdinir A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Ciprofloxacin A second generation fluoroquinolone used to treat various susceptible bacterial infections. Tigecycline A glycylcycline antibiotic used to treat a number of susceptible bacterial infections. Cephalexin A first generation cephalosporin used to treat certain susceptible bacterial infections. Carbenicillin For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria. Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. Nafcillin A penicillin derivative antibiotic used to treat susceptible staphylococcal infections. Cefixime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Tobramycin An aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. Trovafloxacin An antibiotic used to treat gonorrhea and chlamydia. Nitrofurantoin An antibiotic used to treat urinary tract infections. Oxacillin A penicillin antibiotic used to treat a number of susceptible bacterial infections. Hetacillin Hetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin. Tetracycline An antibiotic used to treat a wide variety of susceptible infections. Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body. Roxithromycin An antibiotic used to treat a variety of susceptible bacterial infections. Nalidixic acid A quinolone antibiotic used to treat urinary tract infections. Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Rosoxacin For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Cinoxacin For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and... Fosfomycin A broad spectrum antibiotic used to treat uncomplicated urinary tract infections. Cefaclor A second generation cephalosporin used to treat a wide variety of infections in the body. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Spectinomycin An aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. Ceforanide For the treatment of infections caused by susceptible organisms. Metacycline For the treatment of acute bacterial exacerbations of chronic bronchitis Mezlocillin Used to treat serious gram–negative infections of the lungs, urinary tract, and skin. Dirithromycin An antibiotic used to treat a variety of respiratory, skin, and other infections. Netilmicin An aminoglycoside used to treat a wide variety of infections in the body. Telithromycin An ketolide used to treat community acquired pneumonia of mild to moderate severity. Cyclacillin For the treatment of bacterial infections caused by susceptible organisms. Minocycline A tetracycline analog used to treat a wide variety of infections in the body. Gatifloxacin A fourth generation fluoroquinolone used to treat a wide variety of infections in the body. Norfloxacin A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine. Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Azlocillin For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae. Cefditoren A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract. Cefuroxime A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. Levofloxacin A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. Cefapirin A first generation cephalosporin indicated in the treatment of susceptible bacterial infections. Cefadroxil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis. Cloxacillin An antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections. Cefprozil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. Gemifloxacin A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria. Amdinocillin Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms. Ofloxacin An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. Sparfloxacin A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis. Ceftriaxone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. Rolitetracycline A broad-spectrum tetracycline antibiotic used in cases needing high concentrations or when oral administration is impractical. Josamycin A macrolide antibiotic used for the treatment of various susceptible bacterial infections. Cefamandole A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. Cefazolin A broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract. Cefonicid For the treatment of bacterial infections caused by susceptible microorganisms. Cefoperazone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Cefotetan An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections. Cefoxitin A semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. Ceftizoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea. Cefradine A first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues. Temafloxacin For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. Cefepime A fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. Cefacetrile A broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections. Ceftibuten A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis. Cefpodoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis. Nitroxoline Nitroxoline is an antibiotic agent. Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Imipenem A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. Bacampicillin An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections. Meticillin Used to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as Staphylococcus aureus that would otherwise be resistant to most penicillins. Pivampicillin An ampicillin prodrug used to treat a variety of infections. Pivmecillinam A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs). Tazobactam A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. Ticarcillin A beta lactam antibiotic used to treat a variety of infections in the body. Lincomycin An antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate. Ribostamycin A broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. Latamoxef Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,... Fleroxacin Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. Oritavancin An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria. Spiramycin A macrolide antimicrobial agent used in the treatment of various bacterial infections. Teicoplanin A glycopeptide antibiotic with a similar mechanism of action and spectrum of activity to vancomycin used to treat various infections caused by gram-positive bacteria. Sulfadimethoxine For use in the treatment of infections. Garenoxacin Investigated for use/treatment in bacterial infection. Doripenem An antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. Dalbavancin An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria. Iclaprim Investigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia. Telavancin An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia. Ceftaroline fosamil An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. Nemonoxacin Investigated for use/treatment in bacterial infection and pneumonia. Arbekacin Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA). Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Thiamphenicol A semisynthetic derivative of chloramphenicol with a broad spectrum of antibacterial activity. Azidocillin For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including... Sulfamoxole For the treatment of bacterial infection. Flumequine Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. Cefaloridine Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH. Cefminox Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan. Carindacillin A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA. Procaine benzylpenicillin A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Sulbactam An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Cefroxadine Was used for the treatment of bacterial infections. Oleandomycin Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus. Pazufloxacin Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol). Prulifloxacin A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections. Flomoxef Flomoxef has been used in trials studying the treatment of Urinary Tract Infection. Sultamicillin A mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria. Faropenem Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia. Temocillin Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. Sisomicin Sisomicin has been used in trials studying the treatment of Pyoderma. Secnidazole A nitroimidazole antibiotic used to treat bacterial vaginosis. Ornidazole A nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis. Biapenem A carbapenem antibiotic indicated in the treatment of bacterial infections. Troleandomycin For the treatment of bacterial infection. Clofoctol An antibacterial agent indicated in the treatment of respiratory infections; or prevention of infections after ear, nose, and throat surgery. Sitafloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections. Penimepicycline Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification... Cefatrizine Not Annotated Dibekacin Dibekacin is an aminoglycoside antibiotic marketed in Japan . Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Miocamycin Miocamycin is a macrolide type antimicrobial . This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia . It has shown to... Epicillin Not Annotated Sulfaperin Not Annotated Pheneticillin Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally. Flurithromycin Not Annotated Rokitamycin Not Annotated Midecamycin A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria. Cefcapene Not Annotated Cefodizime A broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria. Furazidin Not Annotated Sulfametomidine Not Annotated Cefsulodin Not Annotated Cefetamet Not Annotated Isepamicin Not Annotated Carumonam Not Annotated Sulfamazone Not Annotated Oxolinic acid Not Annotated Cefbuperazone Not Annotated Propicillin Not Annotated Cefozopran Not Annotated Bekanamycin An aminoglycoside antibiotic indicated in the treatment of eye infections. Cefpirome An antibiotic indicated in the treatment of a wide variety of infections in the body. Clometocillin Not Annotated Sulbenicillin Not Annotated Sulfathiourea Not Annotated Pristinamycin Not Annotated Xibornol A lipophilic antiseptic indicated as an adjunct in the treatment of susceptible oral infections. Nifurtoinol Not Annotated Penamecillin Not Annotated Piromidic acid Not Annotated Rufloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible respiratory infections and uncomplicated cystitis. Sulfamethoxypyridazine A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis. Cefazedone Not Annotated Brodimoprim Not Annotated Talampicillin Not Annotated Aspoxicillin Not Annotated Ceftezole Not Annotated Pipemidic acid A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections. Metampicillin Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the... Erythromycin A macrolide antibiotic used to treat and prevent a variety of bacterial infections. Moxifloxacin A fluoroquinolone antibiotic used to treat various bacterial infections. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Oxytetracycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Demeclocycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Sulfametopyrazine An antibiotic used in the treatment or prevention of bacterial infections and malaria. Tinidazole A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. Lomefloxacin A fluoroquinolone used to prevent and treat a wide variety of infections in the body. Neomycin An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Benzylpenicillin A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. Streptomycin An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. Kanamycin An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. Clindamycin A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. Clarithromycin A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Sulfaphenazole For the treatment bacterial infections. Chlortetracycline The first tetracycline antibiotic most commonly used for veterinary purposes. Mandelic acid Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically. Tedizolid An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections. Sarecycline A tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris. Omadacycline A tetracycline antibiotic used to treat community acquired bacterial pneumonia. Ceftobiprole medocaril A cephalosporin indicated in the treatment of pneumonia. Solithromycin Investigated for the treatment of community-acquired pneumonia (CAP). Delafloxacin A fluoroquinolone antibiotic used to treat skin and skin structure infections. Vaborbactam A beta lactamase inhibitor used to treat complicated urinary tract infections. Eravacycline A tetracycline antibiotic used to treat complicated intra-abdominal infections. Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. Plazomicin An aminoglycoside antibiotic used to treat complicated urinary tract infections. Lefamulin A pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP). Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Tetroxoprim Not Annotated - Drugs & Drug Targets