Antiinfectives for Systemic Use
- Name
- Antiinfectives for Systemic Use
- Accession Number
- DBCAT002131
- Description
Not Available
- ATC Classification
- Drugs
Drug Drug Description Varicella zoster vaccine (live/attenuated) Zostavax vaccine is indicated for the prevention of herpes zoster (shingles) in immunocompetent adults aged 50 years and older. Varivax vaccine is indicated for active immunization for the prevention of... Daptomycin A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus. Enfuvirtide An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. Palivizumab A monoclonal anti respiratory syncytial virus F protein antibody used to prevent serious sequelae caused by respiratory syncytial virus infection in pediatric patients. Fluconazole A triazole antifungal used to treat various fungal infections including candidiasis. Oseltamivir A neuraminidase inhibitor used in the prophylaxis and treatment of influenza. Azithromycin A macrolide antibiotic used to treat a variety of bacterial infections. Nelfinavir A viral protease inhibitor used in the treatment of HIV infection. Indinavir A protease inhibitor used to treat HIV infection. Cefotiam A cephalosporin antibiotic used to treat a variety of bacterial infections. Aminosalicylic acid An aminosalicylate drug used to induce remission in ulcerative colitis. Nevirapine A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. Dapsone A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis. Doxycycline A tetracycline antibiotic used to treat a wide variety of bacterial infections. Lymecycline A tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections. Cycloserine A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI). Cefmenoxime Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria. Cefmetazole A cephalosporin antibiotic used to treat a variety of bacterial infections. Penciclovir A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. Tenofovir disoproxil A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection. Flucloxacillin A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA). Ertapenem A carbapenem antibiotic used for the treatment of moderate to severe infections caused by susceptible bacteria. Capreomycin An aminoglycoside antibiotic used as an adjunct drug in tuberculosis. Piperacillin A penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam susceptible, β-lactamase generating strains of several bacteria. Ethambutol An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). Pyrazinamide An antituberculosis agent used as a component of tuberculosis (TB) treatment. Aztreonam A beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Anidulafungin An antifungal used in the treatment of several types of candida infections. Grepafloxacin A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections. Cidofovir An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS. Ampicillin A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. Phenoxymethylpenicillin A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. Famciclovir A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster. Cefpiramide For treatment of severe infections caused by susceptible bacteria such as P. aeruginosa. Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others. Trimethoprim An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. Entecavir A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases. Loracarbef Used to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,... Clomocycline For the treatment and management of Brucellosis, mycoplasma infection, acne vulgaris, chlamydial infection;Chronic bronchitis Cefalotin A broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. Enoxacin For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria... Rimantadine An RNA synthesis inhibitor used to prevent influenza A infection. Amikacin An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria. Dicloxacillin A penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug. Pefloxacin An antibiotic used to treat a variety of bacterial infections. Cefotaxime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Zidovudine A dideoxynucleoside used in the treatment of HIV infection. Ritonavir An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. Vancomycin A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. Caspofungin An echinocandin used to treat a variety of fungal infections. Foscarnet An antiviral used to treat CMV, HIV, and HSV infections. Cefdinir A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Ciprofloxacin A second generation fluoroquinolone used to treat various susceptible bacterial infections. Zanamivir A neuraminidase inhibitor used to treat influenza A and B. Tigecycline A glycylcycline antibiotic used to treat a number of susceptible bacterial infections. Cephalexin A first generation cephalosporin used to treat certain susceptible bacterial infections. Valaciclovir An guanine nucleoside antiviral used to treat herpes exacerbations. Carbenicillin For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria. Voriconazole A triazole compound used to treat fungal infections. Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. Nafcillin A penicillin derivative antibiotic used to treat susceptible staphylococcal infections. Ethionamide A second line antitubercular agent used to treat tuberculosis when other treatments have failed. Rifabutin An antibiotic used to treat mycobacterium avium complex disease in patients with HIV. Efavirenz A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. Stavudine A dideoxynucleoside used in the treatment of HIV infection. Cefixime A third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Tobramycin An aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. Trovafloxacin An antibiotic used to treat gonorrhea and chlamydia. Nitrofurantoin An antibiotic used to treat urinary tract infections. Amprenavir A protease inhibitor used to treat HIV infection. Delavirdine A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. Lamivudine A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. Oxacillin A penicillin antibiotic used to treat a number of susceptible bacterial infections. Adefovir dipivoxil A nucleotide analog used to treat chronic hepatitis B. Hetacillin Hetacillin is a beta-lactam antibiotic prodrug used to treat bacterial infections. In the body it gets converted to ampicillin. Tetracycline An antibiotic used to treat a wide variety of susceptible infections. Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body. Roxithromycin An antibiotic used to treat a variety of susceptible bacterial infections. Nalidixic acid A quinolone antibiotic used to treat urinary tract infections. Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Ribavirin A guanosine nucleoside used to treat some forms of Hepatitis C. Rosoxacin For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Cinoxacin For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and... Fosfomycin A broad spectrum antibiotic used to treat uncomplicated urinary tract infections. Cefaclor A second generation cephalosporin used to treat a wide variety of infections in the body. Clofazimine A riminophenazine antimycobacterial used to treat leprosy. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Didanosine A reverse transcriptase inhibitor used to treat HIV. Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Spectinomycin An aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. Ceforanide For the treatment of infections caused by susceptible organisms. Metacycline For the treatment of acute bacterial exacerbations of chronic bronchitis Tipranavir A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. Zalcitabine A dideoxynucleoside used to treat HIV. Mezlocillin Used to treat serious gram–negative infections of the lungs, urinary tract, and skin. Isoniazid An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. Dirithromycin An antibiotic used to treat a variety of respiratory, skin, and other infections. Netilmicin An aminoglycoside used to treat a wide variety of infections in the body. Telithromycin An ketolide used to treat community acquired pneumonia of mild to moderate severity. Cyclacillin For the treatment of bacterial infections caused by susceptible organisms. Minocycline A tetracycline analog used to treat a wide variety of infections in the body. Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. Gatifloxacin A fourth generation fluoroquinolone used to treat a wide variety of infections in the body. Rifampicin An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. Abacavir An antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. Norfloxacin A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine. Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Azlocillin For the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae. Cefditoren A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract. Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. Flucytosine An antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus. Cefuroxime A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. Levofloxacin A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. Cefapirin A first generation cephalosporin indicated in the treatment of susceptible bacterial infections. Cefadroxil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis. Micafungin An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. Sulfoxone For the treatment of leprosy and dermatitis herpetiformis Cloxacillin An antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections. Cefprozil A cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. Gemifloxacin A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria. Amdinocillin Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms. Ofloxacin An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. Itraconazole An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. Rifapentine An antibiotic agent used in the treatment of pulmonary tuberculosis. Sparfloxacin A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis. Ceftriaxone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. Saquinavir An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. Posaconazole A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. Telbivudine A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). Rolitetracycline A broad-spectrum tetracycline antibiotic used in cases needing high concentrations or when oral administration is impractical. Fosamprenavir An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. Josamycin A macrolide antibiotic used for the treatment of various susceptible bacterial infections. Cefamandole A beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. Cefazolin A broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract. Cefonicid For the treatment of bacterial infections caused by susceptible microorganisms. Cefoperazone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Cefotetan An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections. Cefoxitin A semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. Ceftizoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea. Cefradine A first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues. Temafloxacin For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. Cefepime A fourth-generation cephalosporin antibiotic used in the treatment of infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. Cefacetrile A broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections. Ceftibuten A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis. Cefpodoxime A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis. Nitroxoline Nitroxoline is an antibiotic agent. Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Imipenem A carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. Lopinavir An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. Bacampicillin An ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections. Meticillin Used to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as Staphylococcus aureus that would otherwise be resistant to most penicillins. Pivampicillin An ampicillin prodrug used to treat a variety of infections. Pivmecillinam A prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs). Tazobactam A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. Ticarcillin A beta lactam antibiotic used to treat a variety of infections in the body. Valganciclovir An antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). Lincomycin An antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate. Ribostamycin A broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. Latamoxef Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,... Fleroxacin Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. Maraviroc A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. Oritavancin An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria. Pleconaril Investigated for use/treatment in upper respiratory infection. Telaprevir An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. Spiramycin A macrolide antimicrobial agent used in the treatment of various bacterial infections. Teicoplanin A glycopeptide antibiotic with a similar mechanism of action and spectrum of activity to vancomycin used to treat various infections caused by gram-positive bacteria. Sulfadimethoxine For use in the treatment of infections. Garenoxacin Investigated for use/treatment in bacterial infection. Doripenem An antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. Dalbavancin An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria. Maribavir A cytomegalovirus (CMV) pUL97 kinase inhibitor used for the treatment of refractory post-transplant CMV infection. Motavizumab Investigated for use/treatment in viral infection and pediatric indications. Iclaprim Investigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia. Telavancin An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia. Etravirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. Ceftaroline fosamil An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. Nemonoxacin Investigated for use/treatment in bacterial infection and pneumonia. Clevudine Investigated for use/treatment in hepatitis (viral, B). Arbekacin Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA). Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Raltegravir An antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Thiamphenicol A semisynthetic derivative of chloramphenicol with a broad spectrum of antibacterial activity. Azidocillin For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including... Sulfamoxole For the treatment of bacterial infection. Rilpivirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). Boceprevir A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. Raxibacumab A monoclonal antibody used in conjunction with an antibacterial regimen to treat patients with inhalational anthrax caused by Bacillus anthracis and for prophylaxis of inhalational anthrax when appropriate. Bedaquiline A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). Dolutegravir An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents. Sofosbuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Flumequine Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. Cefaloridine Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH. Ledipasvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Cefminox Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan. Cobicistat A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. Elvitegravir An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Daclatasvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Paritaprevir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Tenofovir alafenamide A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease. Carindacillin A penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA. Procaine benzylpenicillin A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Sulbactam An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Rabies virus inactivated antigen, B Inactivated rabies virus antigen B is indicated for pre- and post-exposure prophylaxis against rabies. Rotavirus vaccine Rotarix is indicated for prevention of rotavirus gastroenteritis caused by G1, G3, G4, and G9 types in infants aged 6-24 weeks [FDA Label]. Rotateq is indicated for the prevention of... Rabies virus inactivated antigen, A Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the... Rubella virus vaccine A vaccine used to prevent Rubella. Clostridium tetani toxoid antigen (formaldehyde inactivated) Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention... Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) Not Annotated Cefroxadine Was used for the treatment of bacterial infections. Oleandomycin Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus. Asunaprevir An NS3 protease inhibitor used to treat hepatitis C genotype 1b. Tetanus immune globulin, human A solution of antibodies used to prevent tetanus after an injury. Isavuconazole Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of... Delamanid An antibiotic used to treat multidrug resistant tuberculosis. Pazufloxacin Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol). Faldaprevir Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. Prulifloxacin A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections. Flomoxef Flomoxef has been used in trials studying the treatment of Urinary Tract Infection. Sultamicillin A mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria. Faropenem Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia. Temocillin Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. Sisomicin Sisomicin has been used in trials studying the treatment of Pyoderma. Protionamide An antitubercular thioamide-derivative used in the treatment of multi-drug resistant (MDR) tuberculosis and leprosy. Amithiozone Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection. Secnidazole A nitroimidazole antibiotic used to treat bacterial vaginosis. Terizidone Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug Resistant Tuberculosis, and Extensively-drug Resistant Tuberculosis. Ornidazole A nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis. Biapenem A carbapenem antibiotic indicated in the treatment of bacterial infections. Inosine pranobex A medication used to treat subacute sclerosing panencephalitis. Troleandomycin For the treatment of bacterial infection. Clofoctol An antibacterial agent indicated in the treatment of respiratory infections; or prevention of infections after ear, nose, and throat surgery. Sitafloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections. Penimepicycline Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification... Cefatrizine Not Annotated Dibekacin Dibekacin is an aminoglycoside antibiotic marketed in Japan . Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Miocamycin Miocamycin is a macrolide type antimicrobial . This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia . It has shown to... Epicillin Not Annotated Sulfaperin Not Annotated Pheneticillin Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally. Flurithromycin Not Annotated Rokitamycin Not Annotated Morinamide A second-line pyrazine anti-tuberculosis agent. Midecamycin A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria. Cefcapene Not Annotated Cefodizime A broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria. Furazidin Not Annotated Sulfametomidine Not Annotated Cefsulodin Not Annotated Cefetamet Not Annotated Nebacumab Not Annotated Isepamicin Not Annotated Carumonam Not Annotated Sulfamazone Not Annotated Moroxydine Not Annotated Tiocarlide Not Annotated Umifenovir A dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses. Oxolinic acid Not Annotated Cefbuperazone Not Annotated Metisazone Not Annotated Propicillin Not Annotated Cefozopran Not Annotated Bekanamycin An aminoglycoside antibiotic indicated in the treatment of eye infections. Cefpirome An antibiotic indicated in the treatment of a wide variety of infections in the body. Clometocillin Not Annotated Sulbenicillin Not Annotated Sulfathiourea Not Annotated Pristinamycin Not Annotated Xibornol A lipophilic antiseptic indicated as an adjunct in the treatment of susceptible oral infections. Nifurtoinol Not Annotated Penamecillin Not Annotated Piromidic acid Not Annotated Rufloxacin A fluoroquinolone antibiotic indicated in the treatment of susceptible respiratory infections and uncomplicated cystitis. Sulfamethoxypyridazine A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis. Cefazedone Not Annotated Brodimoprim Not Annotated Talampicillin Not Annotated Aspoxicillin Not Annotated Ceftezole Not Annotated Pipemidic acid A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections. Metampicillin Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the... Human cytomegalovirus immune globulin A solution of immune globulin G against cytomegalovirus used to prevent transmission of cytomegalovirus after organ transplants. Vidarabine An antiviral agent used to treat various viral infections. Erythromycin A macrolide antibiotic used to treat and prevent a variety of bacterial infections. Moxifloxacin A fluoroquinolone antibiotic used to treat various bacterial infections. Idoxuridine A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Oxytetracycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Demeclocycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Sulfametopyrazine An antibiotic used in the treatment or prevention of bacterial infections and malaria. Amphotericin B An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. Acyclovir A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. Tinidazole A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. Lomefloxacin A fluoroquinolone used to prevent and treat a wide variety of infections in the body. Neomycin An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. Ganciclovir A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Benzylpenicillin A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. Streptomycin An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. Kanamycin An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. Clindamycin A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. Clarithromycin A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Simeprevir A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. Sulfaphenazole For the treatment bacterial infections. Chlortetracycline The first tetracycline antibiotic most commonly used for veterinary purposes. Mandelic acid Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically. Lysozyme An enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex. Tromantadine Tromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex. Hachimycin Not Annotated Tedizolid An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections. Sarecycline A tetracycline antibiotic used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris. Omadacycline A tetracycline antibiotic used to treat community acquired bacterial pneumonia. Brivudine A drug used to treat herpes zoster. Yellow fever vaccine Yellow Fever Vaccine is indicated for active immunization for the prevention of yellow fever in persons 9 months of age and older in the following categories: Persons Living in or... Rifamycin An antibacterial used to treat traveler's diarrhea. Ceftobiprole medocaril A cephalosporin indicated in the treatment of pneumonia. Obiltoxaximab A monoclonal antibody used for prophylaxis or treatment of inhalational anthrax. Peramivir An intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days. Solithromycin Investigated for the treatment of community-acquired pneumonia (CAP). Elbasvir An antiviral and NS5A inhibitor used to treat hepatitis C infections. Grazoprevir An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. Velpatasvir A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis. Bictegravir An integrase inhibitor used to treat HIV infections. Delafloxacin A fluoroquinolone antibiotic used to treat skin and skin structure infections. Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Letermovir An antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). Vaborbactam A beta lactamase inhibitor used to treat complicated urinary tract infections. Doravirine A non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections. Eravacycline A tetracycline antibiotic used to treat complicated intra-abdominal infections. Ibalizumab A CD4-specific antibody used to treat HIV infections. Bezlotoxumab A monoclonal antibody used to reduce the recurrence of Clostridium difficile infections. Pibrentasvir A Hepatitis C NS5A inhibitor used to treat Hepatitis C. Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. Pyridoxine A vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy. Enviomycin Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin. Amenamevir Amenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir. Tecovirimat An antiviral medication used to treat smallpox, monkeypox, and cowpox. Beclabuvir Beclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic. Favipiravir An antiviral used to manage influenza, and that has the potential to target other viral infections. Plazomicin An aminoglycoside antibiotic used to treat complicated urinary tract infections. Laninamivir Laninamivir has been used in trials studying the treatment of Influenza. Lefamulin A pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP). Baloxavir marboxil A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza. Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Tetroxoprim Not Annotated Hepatitis B immune globulin An injection of immunoglobulin G (IgG) antibodies to prevent the development of chronic Hepatitis B infection. Typhoid Vi polysaccharide vaccine Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for... Human Rho(D) immune globulin A solution of antibodies used to prevent isoimmunization of Rho(D) negative patients exposed to Rho(D) positive blood in pregnancy or transfusion. Hepatitis B Vaccine (Recombinant) A solution of Hepatitis B surface antigen used to immunize patients against Hepatitis B. Tebipenem pivoxil Not Annotated Tosufloxacin Not Annotated Pretomanid Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis. Cabotegravir An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection. Fostemsavir An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein. Brincidofovir An oral lipid prodrug of cidofovir used in the treatment of human smallpox disease. Relebactam A beta-lactamase inhibitor used to prevent hydrolysis of beta-lactam antibiotics, leading to increased effectiveness. Oteseconazole An azole antifungal used to prevent recurrent vulvovaginal candidiasis in females who are not of reproductive potential. Remdesivir A nucleoside analog used to treat RNA virus infections including COVID-19. Cefiderocol A cephalosporin antibiotic used in complicated urinary tract infections. Bulevirtide A drug for the treatment of chronic Hepatitis D infection in adults with compensated liver disease. Coblopasvir Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C). Lenacapavir A first-in-class capsid inhibitor being investigated for use in HIV-1 treatment. Levonadifloxacin Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)). Cilgavimab An extended half-life recombinant monoclonal IgG1κ antibody directed against the SARS-CoV-2 S protein for COVID-19 prophylaxis in individuals unable to undergo COVID-19 immunization. Tixagevimab An extended half-life recombinant monoclonal IgG1κ antibody directed against the SARS-CoV-2 S protein for COVID-19 prophylaxis in individuals unable to undergo COVID-19 immunization. - Drugs & Drug Targets