Tryptamines

Name
Tryptamines
Accession Number
DBCAT001049
Description

Derivatives of TRYPTAMINES that are SEROTONIN RECEPTOR AGONISTS acting at 5-HT1 RECEPTORS. Some are used to treat MIGRAINE DISORDERS.

Drugs
DrugDrug Description
5-Methoxy-N,N-diisopropyltryptamine5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a...
5-methoxy-N,N-dimethyltryptamine5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug,...
BufotenineA hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a...
DimethyltryptamineSome people use this compound as a psychedelic inducing agent.
MelatoninAn endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement.
N-acetylserotoninNot Available
PsilocybinPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
SerotoninFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
SumatriptanA serotonin receptor agonist used to treat migraines and cluster headaches.
TIK-301Not Annotated
Drugs & Drug Targets
DrugTargetType
5-Methoxy-N,N-diisopropyltryptamineCytochrome P450 2C9enzyme
5-Methoxy-N,N-diisopropyltryptamineCytochrome P450 1A1enzyme
5-Methoxy-N,N-diisopropyltryptamineCytochrome P450 2C19enzyme
5-Methoxy-N,N-diisopropyltryptamineCytochrome P450 3A4enzyme
5-Methoxy-N,N-diisopropyltryptamineCytochrome P450 2C8enzyme
5-Methoxy-N,N-diisopropyltryptamineCytochrome P450 1A2enzyme
5-Methoxy-N,N-diisopropyltryptamineCytochrome P450 2D6enzyme
5-Methoxy-N,N-diisopropyltryptamine5-hydroxytryptamine receptor 2Ctarget
5-Methoxy-N,N-diisopropyltryptamine5-hydroxytryptamine receptor 2Atarget
5-Methoxy-N,N-diisopropyltryptamineSodium-dependent serotonin transportertarget
5-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 2Ctarget
5-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 2Btarget
5-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 6target
5-methoxy-N,N-dimethyltryptamineCytochrome P450 2D6enzyme
5-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
5-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 1Atarget
Bufotenine5-hydroxytryptamine receptor 5Atarget
Bufotenine5-hydroxytryptamine receptor 7target
Bufotenine5-hydroxytryptamine receptor 6target
Bufotenine5-hydroxytryptamine receptor 2Atarget
Bufotenine5-hydroxytryptamine receptor 1Dtarget
BufotenineAmine oxidase [flavin-containing] Aenzyme
Dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
Dimethyltryptamine5-hydroxytryptamine receptor 6target
DimethyltryptamineSigma non-opioid intracellular receptor 1target
MelatoninOrganic anion transporter 3transporter
MelatoninAromataseenzyme
MelatoninCalmodulintarget
MelatoninMelatonin receptor type 1Btarget
MelatoninCytochrome P450 1B1enzyme
MelatoninMyeloperoxidaseenzyme
MelatoninIndoleamine 2,3-dioxygenase 1enzyme
MelatoninAcetylserotonin O-methyltransferaseenzyme
MelatoninCytochrome P450 2C9enzyme
MelatoninCytochrome P450 2C19enzyme
MelatoninCytochrome P450 1A2enzyme
MelatoninCytochrome P450 1A1enzyme
MelatoninEosinophil peroxidasetarget
MelatoninEstrogen receptortarget
MelatoninMyeloperoxidasetarget
MelatoninRibosyldihydronicotinamide dehydrogenase [quinone]target
MelatoninCalreticulintarget
MelatoninNuclear receptor ROR-betatarget
MelatoninMelatonin receptor type 1Atarget
N-acetylserotoninSepiapterin reductasetarget
N-acetylserotoninMelatonin receptor type 1Atarget
Psilocybin5-hydroxytryptamine receptor 2Atarget
SerotoninSolute carrier family 22 member 2transporter
SerotoninSodium-dependent serotonin transportertarget
Serotonin5-hydroxytryptamine receptor 2Atarget
Serotonin5-hydroxytryptamine receptor 3Atarget
Serotonin5-hydroxytryptamine receptor 3Btarget
SerotoninSynaptic vesicular amine transportertarget
Serotonin5-hydroxytryptamine receptor 1Btarget
Serotonin5-hydroxytryptamine receptor 2Ctarget
Serotonin5-hydroxytryptamine receptor 4target
Serotonin5-hydroxytryptamine receptor 5Atarget
Serotonin5-hydroxytryptamine receptor 1Dtarget
Serotonin5-hydroxytryptamine receptor 6target
Serotonin5-hydroxytryptamine receptor 1Atarget
Serotonin5-hydroxytryptamine receptor 2Btarget
SerotoninAdenosine receptor A3target
Serotonin5-hydroxytryptamine receptor 7target
Sumatriptan5-hydroxytryptamine receptor 1Dtarget
SumatriptanSolute carrier organic anion transporter family member 1B1transporter
SumatriptanBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
SumatriptanATP-dependent translocase ABCB1transporter
SumatriptanSolute carrier organic anion transporter family member 1A2transporter
Sumatriptan5-hydroxytryptamine receptor 1Atarget
SumatriptanAmine oxidase [flavin-containing] Aenzyme
Sumatriptan5-hydroxytryptamine receptor 1Ftarget
Sumatriptan5-hydroxytryptamine receptor 1Btarget
TIK-301Melatonin receptor type 1Atarget