- Accession Number
A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.
Drug Drug Description Creatine For nutritional supplementation, also for treating dietary shortage or imbalance. Bethanidine For the treatment of hypertension. Metformin A biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS). Cimetidine A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. Guanidine A strong organic base used to treat muscle weakness and fatigue associated with the myasthenic complications of Eaton-Lambert syndrome. Zanamivir A neuraminidase inhibitor used to treat influenza A and B. Guanabenz An alpha-2 adrenergic agonist used to treat hypertension. Chlorhexidine An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis. Phenformin For the reatment of type II diabetes mellitus. Guanfacine An alpha-2A adrenergic receptor agonist used to treat ADHD. Proguanil A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria. Guanethidine An antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension. Buformin Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of... Iobenguane A radiopharmaceutical agent used for the diagnosis of primary and metastatic pheochromocytoma or neuroblastoma. Pinacidil Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood... Agmatine Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,... Robenidine Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. Robenidine is used to control coccidiosis, a lethal infection in poultry which... Laninamivir octanoate Laninamivir octanoate has been used in trials studying the treatment of Asthma. Polihexanide Polihexanide has been used in trials studying the treatment, prevention, and supportive care of Caries, Neoplasm, Skin Diseases, Nail Diseases, and Dental Plaque, among others. Chlorproguanil Chlorproguanil has been used in trials studying the treatment of MALARIA. It is a dichloro-derivative of chloroguanide. Laninamivir Laninamivir has been used in trials studying the treatment of Influenza. Gabexate A protease inhibitor indicated in the treatment of acute pancreatitis. Mitoguazone Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin. Phosphocreatine A cardioprotective agent indicated for use in cardiac surgery. Guanoxabenz Not Annotated Guanazodine Not Annotated Ambazone Not Annotated Sulfaguanidine Not Annotated Camostat A serine protease indicated in Japan to treat chronic pancreatitis. Cycloguanil Cycloguanil is the active metabolite of proguanil. Polyaminopropyl biguanide Not Annotated
- Drugs & Drug Targets