Amidines

DBCAT000343Pharmacologic class

Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. Amidines include carboxamidines, sulfinamidines and phosphinamidines. A DrugBank category of 83 drugs. 24 of them are approved.

Drugs: 2-butyl-1-hydroxyguanidine
4-guanidinobenzoic acid
Agmatine
Ambazone
Anisperimus
Aptiganel
Avoralstat
Benzamidine
Bethanidine
Biguanide
Brilacidin
Brostallicin
Buformin
Camostat
Cariporide
Chlorhexidine
Chlorproguanil
CHS-828
Cimetidine
Creatine
Cycloguanil
Deoxyspergualin
Dibrompropamidine
Diminazene
Diphenylguanidine
and 58 more with a free account

What you can answer from here — as of August 24, 2016

83DrugsEach linked to its full drug card

121Drug targetsEvery drug–target pair in the class, with bond type

6,670Marketed productsAcross the regions we cover, with dosage forms and routes

30Routes of administrationHow the drugs in this class are given

Which targets do Amidines share, and which companies have late-stage candidates in this class?

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