- Accession Number
Organic compounds that contain the (-NH2OH) radical.
Drug Drug Description Aminooxyacetic acid A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem] Dabrafenib A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. Fluvoxamine A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. Acetohydroxamic acid A synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. Pralidoxime A cholinesterase reactivator used to treat organophosphate poisoning. Deferoxamine A chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias. Marimastat For the treatment of various cancers SC-74020 Not Available Coprogen Not Available Benzhydroxamic Acid Not Available Indirubin-3'-monoxime Not Available WAY-151693 Not Available Ilomastat Not Available Glutamine hydroxamate Not Available Vorinostat A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Not Available Filaminast Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). As such, has potential in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Gallichrome Not Available 6-bromoindirubin-3'-oxime Not Available Xylarohydroxamate Not Available Trichostatin A Not Available Bb-3497 Not Available 4-Phospho-D-erythronohydroxamic acid Not Available Brasofensine For the treatment of Parkinson's Disease. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). PG-530742 Investigated for use/treatment in osteoarthritis. LX-2931 Investigated for use/treatment in rheumatoid arthritis, inflammatory disorders (unspecified), and autoimmune diseases. Darapladib Investigated for use/treatment in atherosclerosis. Panobinostat A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. Asoprisnil Investigated for use/treatment in uterine fibroids. Norelgestromin A progestin used for the prevention of pregnancy in women who elect to use a transdermal patch as a method of contraception. CGS-27023 Not Available CTS-1027 CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection. Adrafinil Used to relieve excessive sleepiness and inattention in elderly patients. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Technetium Tc-99m exametazime A radiopharmaceutical diagnostic agent used as an adjunct for scintigraphy in the detection of altered regional cerebral perfusion in stroke. Epacadostat Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others. Tosedostat Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the... Lanopepden Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial. CUDC-101 CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others. CG-200745 Cg200745 has been used in trials studying the treatment of Solid Tumour. Ricolinostat Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer. R-306465 R306465 has been used in trials studying the treatment of Neoplasms. Resminostat Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others. Abexinostat Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase... Pyroxamide Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others. Didox Didox has been used in trials studying the supportive care of Gastric Cancer. Quisinostat Quisinostat has been used in trials studying the treatment of Lymphoma, Neoplasms, Myelodysplastic Syndromes, and Advanced or Refractory Leukemia. Upamostat Upamostat has been used in trials studying the treatment of Pancreatic Cancer. Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Obidoxime Not Annotated Reposal Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia. Martinostat Martinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer). Tefinostat Tefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)). Glucoraphanin Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]). TRO40303 TRO40303 is under investigation in clinical trial NCT01374321 (Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction). GSK2256098 GSK2256098 is under investigation in clinical trial NCT02523014 (Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas). Nolasiban Nolasiban is under investigation in clinical trial NCT03081208 (Phase 3 Placebo Controlled Study of Nolasiban to Improve Pregnancy Rates in Women Undergoing IVF/ICSI). Caprylhydroxamic acid Not Annotated NP-51 Not Annotated Dacinostat Dacinostat is a novel histone deacetylase inhibitor.
- Drugs & Drug Targets