Folitixorin
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Folitixorin
- DrugBank Accession Number
- DB17113
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 457.447
Monoisotopic: 457.170981489 - Chemical Formula
- C20H23N7O6
- Synonyms
- 5,10-methylene-(6rs)-tetrahydrofolic acid
- 5,10-methylene-5,6,7,8-tetrahydrofolic acid
- 5,10-methylenetetrafolate
- 5,10-methylenetetrahydrofolic acid
- Folic acid, tetrahydro-n5,n10-methylene-
- L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)-
- N5,n10-methylene-5,6,7,8-tetrahydrofolic acid
- N5,n10-methylenetetrahydrofolic acid
- N5,n10-methylenetetrahydropteroylglutamic acid
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0SXY5ET48B
- CAS number
- 3432-99-3
- InChI Key
- QYNUQALWYRSVHF-ABLWVSNPSA-N
- InChI
- InChI=1S/C20H23N7O6/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29/h1-4,12-13H,5-9H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31)/t12?,13-/m0/s1
- IUPAC Name
- (2S)-2-[(4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid
- SMILES
- NC1=NC2=C(N3CN(CC3CN2)C2=CC=C(C=C2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)C(=O)N1
References
- General References
- Not Available
- External Links
- ChemSpider
- 97272
- ChEBI
- 20502
- ChEMBL
- CHEMBL117348
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.823 mg/mL ALOGPS logP -0.94 ALOGPS logP -0.42 Chemaxon logS -2.8 ALOGPS pKa (Strongest Acidic) 3.24 Chemaxon pKa (Strongest Basic) 0.69 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 11 Chemaxon Hydrogen Donor Count 6 Chemaxon Polar Surface Area 189.69 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 123.96 m3·mol-1 Chemaxon Polarizability 45.76 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at November 15, 2022 22:53 / Updated at December 01, 2022 11:35