Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen
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Overview
- Description
- A component of a live influenza vaccine that utilizes weakened influenza virus to generate an immune response.
- Description
- A component of a live influenza vaccine that utilizes weakened influenza virus to generate an immune response.
- DrugBank ID
- DB18661
- Type
- Biotech
- Clinical Trials
- Phase 0
- 0
- Phase 1
- 0
- Phase 2
- 0
- Phase 3
- 0
- Phase 4
- 0
Identification
- Summary
Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is a component of a live attenuated influenza vaccine.
- Brand Names
- FluMist, FluMist Quadrivalent
- Generic Name
- Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen
- DrugBank Accession Number
- DB18661
- Background
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in an immunological defense against future exposure to the virus, or "antigen". This defense includes the production of humoral immunity through the development of antibodies and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus.
There are three basic types of vaccines available: inactivated influenza vaccine (IIV), live attenuated influenza vaccine (LAIV), and recombinant influenza vaccines (RIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde. Inactivated viruses cannot replicate and thus cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability. Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes.
- Type
- Biotech
- Groups
- Approved
- Biologic Classification
- Vaccines
Attenuated - Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcetylsalicylic acid The risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Acetylsalicylic acid. Aminosalicylic acid The risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Aminosalicylic acid. Balsalazide The risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Balsalazide. Bismuth subsalicylate The risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Bismuth subsalicylate. Choline salicylate The risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Choline salicylate. - Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image FluMist Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza A Virus A/Thailand/8/2022 IVR-237 (H3N2) whole (10000000 [FFU]/0.2mL) + Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen (10000000 [FFU]/0.2mL) Spray Nasal MedImmune, LLC 2024-08-06 Not applicable US FluMist Quadrivalent Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza A virus A/Norway/16606/2021 (H3N2) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen (10000000 [FFU]/0.2mL) Spray Nasal MedImmune, LLC 2023-08-14 2025-03-03 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Not Available
- CAS number
- Not Available
References
- General References
- Not Available
- External Links
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Spray Nasal - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at October 10, 2023 20:29 / Updated at October 11, 2023 10:34