Familial Cold Autoinflammatory Syndrome (FCAS)
Also known as: Familial Cold Autoinflam Syn (FCAS) / Familial Cold Autoinflammatory Syndromes / Familial Cold Urticaria / Familial Cold Auto-inflammatory Syndrome / Familial Cold Autoinflammatory Syndrome / Chronic infantile neurological, cutaneous and articular syndrome [CINCA] / FCAS / Familial cold urticaria (disorder)
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB06168 | Canakinumab | An interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA). |
| DB06372 | Rilonacept | An IL-1 inhibitor used to treat cryopyrin-associated periodic syndrome, a rare hereditary inflammatory disorder. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB06168 | Canakinumab | Interleukin-1 beta | target |
| DB06372 | Rilonacept | Interleukin-1 beta | target |
| DB06372 | Rilonacept | Interleukin-1 alpha | target |
| DB06372 | Rilonacept | Interleukin-1 receptor antagonist protein | target |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB00026 | Anakinra | 1 | Completed | 1 |
| DB06168 | Canakinumab | 3 | Completed | 4 |
| DB06372 | Rilonacept | 3 | Completed | 1 |