Primary Hyperoxaluria Type 1 (PH1)
Also known as: Primary Hyperoxaluria Type I / Primary Hyperoxaluria Type 1 / Primary hyperoxaluria, type I (disorder)
Drug | Drug Name | Drug Description |
---|---|---|
DB15935 | Lumasiran | Lumasiran is an interfering RNA that silences hydroxyacid oxidase 1 for the treatment of primary hypoxaluria type 1. |
DB17635 | Nedosiran | An antisense oligonucleotide used to treat primary hyperoxaluria type 1 in adults and high oxalate levels in children |
Drug | Drug Name | Target | Type |
---|---|---|---|
DB15935 | Lumasiran | Hydroxyacid oxidase 1 | target |
DB15935 | Lumasiran | Serum albumin | carrier |
DB15935 | Lumasiran | Cytochrome P450 2C8 | enzyme |
DB17635 | Nedosiran | L-lactate dehydrogenase A chain | target |